| UniProt: | P39361 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12552 | ||
| Length: | 260 (249) | ||
| Sequences: | 3441 | ||
| Seq/Len: | 13.82 |
| SGCR
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 111_L | 209_M | 3.602 | 1.00 | |
| 98_D | 171_R | 3.228 | 1.00 | |
| 89_L | 92_T | 3.033 | 1.00 | |
| 172_A | 203_S | 2.75 | 1.00 | |
| 103_D | 196_K | 2.726 | 1.00 | |
| 140_E | 147_L | 2.53 | 1.00 | |
| 171_R | 207_I | 2.189 | 1.00 | |
| 15_Y | 30_L | 2.162 | 1.00 | |
| 113_K | 132_E | 2.111 | 1.00 | |
| 200_I | 224_A | 2.059 | 1.00 | |
| 101_F | 169_V | 1.989 | 1.00 | |
| 207_I | 231_T | 1.924 | 1.00 | |
| 171_R | 205_E | 1.906 | 1.00 | |
| 231_T | 254_F | 1.9 | 1.00 | |
| 222_A | 225_T | 1.896 | 1.00 | |
| 90_A | 173_F | 1.896 | 1.00 | |
| 90_A | 209_M | 1.893 | 1.00 | |
| 169_V | 199_I | 1.85 | 1.00 | |
| 123_I | 169_V | 1.837 | 1.00 | |
| 15_Y | 19_H | 1.835 | 1.00 | |
| 96_D | 118_A | 1.828 | 1.00 | |
| 238_L | 243_A | 1.817 | 1.00 | |
| 101_F | 199_I | 1.817 | 1.00 | |
| 27_A | 38_V | 1.802 | 1.00 | |
| 94_I | 115_L | 1.798 | 1.00 | |
| 200_I | 206_V | 1.78 | 1.00 | |
| 122_V | 139_V | 1.757 | 1.00 | |
| 212_H | 235_D | 1.755 | 1.00 | |
| 11_Q | 14_H | 1.751 | 1.00 | |
| 95_K | 98_D | 1.746 | 1.00 | |
| 205_E | 231_T | 1.744 | 1.00 | |
| 102_L | 108_C | 1.723 | 1.00 | |
| 88_A | 114_C | 1.716 | 1.00 | |
| 243_A | 247_Q | 1.712 | 1.00 | |
| 111_L | 173_F | 1.709 | 1.00 | |
| 84_R | 110_E | 1.702 | 1.00 | |
| 98_D | 170_E | 1.68 | 1.00 | |
| 162_E | 165_N | 1.656 | 1.00 | |
| 79_Q | 213_S | 1.644 | 1.00 | |
| 91_R | 114_C | 1.642 | 1.00 | |
| 144_I | 160_A | 1.635 | 1.00 | |
| 225_T | 228_C | 1.634 | 1.00 | |
| 110_E | 113_K | 1.607 | 1.00 | |
| 165_N | 198_R | 1.587 | 1.00 | |
| 33_Y | 38_V | 1.571 | 1.00 | |
| 87_A | 114_C | 1.57 | 1.00 | |
| 104_S | 154_S | 1.57 | 1.00 | |
| 170_E | 204_R | 1.569 | 1.00 | |
| 143_I | 155_V | 1.557 | 1.00 | |
| 130_A | 143_I | 1.545 | 1.00 | |
| 9_I | 48_Q | 1.507 | 1.00 | |
| 185_I | 208_L | 1.507 | 1.00 | |
| 79_Q | 82_A | 1.506 | 1.00 | |
| 42_F | 59_L | 1.493 | 1.00 | |
| 13_L | 16_L | 1.483 | 1.00 | |
| 13_L | 52_M | 1.479 | 1.00 | |
| 11_Q | 15_Y | 1.47 | 1.00 | |
| 97_G | 119_R | 1.455 | 1.00 | |
| 162_E | 166_A | 1.451 | 1.00 | |
| 21_H | 60_D | 1.449 | 1.00 | |
| 144_I | 163_M | 1.443 | 1.00 | |
| 89_L | 254_F | 1.438 | 1.00 | |
| 148_I | 155_V | 1.421 | 1.00 | |
| 173_F | 207_I | 1.42 | 1.00 | |
| 122_V | 133_L | 1.388 | 0.99 | |
| 244_Q | 248_R | 1.372 | 0.99 | |
| 144_I | 155_V | 1.371 | 0.99 | |
| 19_H | 26_Q | 1.371 | 0.99 | |
| 93_M | 233_I | 1.369 | 0.99 | |
| 48_Q | 52_M | 1.368 | 0.99 | |
| 36_A | 40_R | 1.363 | 0.99 | |
| 161_L | 194_G | 1.349 | 0.99 | |
| 215_F | 232_I | 1.347 | 0.99 | |
| 165_N | 201_Q | 1.344 | 0.99 | |
| 198_R | 201_Q | 1.341 | 0.99 | |
| 198_R | 202_R | 1.333 | 0.99 | |
| 206_V | 229_I | 1.331 | 0.99 | |
| 10_K | 14_H | 1.329 | 0.99 | |
| 208_L | 229_I | 1.315 | 0.99 | |
| 91_R | 111_L | 1.314 | 0.99 | |
| 93_M | 207_I | 1.308 | 0.99 | |
| 15_Y | 22_L | 1.289 | 0.99 | |
| 96_D | 117_D | 1.28 | 0.99 | |
| 87_A | 91_R | 1.276 | 0.99 | |
| 239_P | 242_I | 1.275 | 0.99 | |
| 121_K | 142_Y | 1.253 | 0.99 | |
| 84_R | 114_C | 1.249 | 0.99 | |
| 11_Q | 31_F | 1.245 | 0.98 | |
| 215_F | 238_L | 1.234 | 0.98 | |
| 147_L | 191_F | 1.226 | 0.98 | |
| 12_M | 27_A | 1.225 | 0.98 | |
| 185_I | 229_I | 1.217 | 0.98 | |
| 72_F | 106_S | 1.213 | 0.98 | |
| 160_A | 195_V | 1.196 | 0.98 | |
| 178_A | 186_T | 1.196 | 0.98 | |
| 96_D | 119_R | 1.194 | 0.98 | |
| 91_R | 94_I | 1.185 | 0.98 | |
| 205_E | 230_K | 1.181 | 0.98 | |
| 24_T | 42_F | 1.179 | 0.98 | |
| 23_S | 26_Q | 1.175 | 0.98 | |
| 16_L | 53_I | 1.167 | 0.97 | |
| 80_S | 110_E | 1.164 | 0.97 | |
| 176_C | 223_V | 1.163 | 0.97 | |
| 179_L | 215_F | 1.16 | 0.97 | |
| 11_Q | 30_L | 1.158 | 0.97 | |
| 112_A | 133_L | 1.15 | 0.97 | |
| 22_L | 27_A | 1.139 | 0.97 | |
| 83_K | 106_S | 1.136 | 0.97 | |
| 105_G | 108_C | 1.132 | 0.97 | |
| 176_C | 210_A | 1.128 | 0.97 | |
| 16_L | 61_F | 1.122 | 0.97 | |
| 179_L | 210_A | 1.121 | 0.97 | |
| 82_A | 235_D | 1.117 | 0.96 | |
| 224_A | 228_C | 1.115 | 0.96 | |
| 15_Y | 18_Q | 1.108 | 0.96 | |
| 25_Q | 35_E | 1.107 | 0.96 | |
| 176_C | 208_L | 1.105 | 0.96 | |
| 121_K | 140_E | 1.095 | 0.96 | |
| 55_G | 58_C | 1.085 | 0.96 | |
| 53_I | 59_L | 1.082 | 0.96 | |
| 108_C | 111_L | 1.081 | 0.95 | |
| 90_A | 233_I | 1.06 | 0.95 | |
| 90_A | 111_L | 1.057 | 0.95 | |
| 207_I | 233_I | 1.041 | 0.94 | |
| 107_T | 211_D | 1.031 | 0.94 | |
| 201_Q | 228_C | 1.029 | 0.94 | |
| 9_I | 44_Y | 1.026 | 0.94 | |
| 112_A | 132_E | 1.025 | 0.93 | |
| 149_R | 192_E | 1.021 | 0.93 | |
| 244_Q | 247_Q | 1.019 | 0.93 | |
| 82_A | 212_H | 1.013 | 0.93 | |
| 93_M | 254_F | 1.004 | 0.93 | |
| 17_W | 61_F | 1.003 | 0.93 | |
| 164_I | 198_R | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9346 | 100 | 0.506 | Contact Map | 0.271 |
| 3rrlB | 2 | 0.6654 | 100 | 0.518 | Contact Map | 0.587 |
| 2w48A | 4 | 0.9038 | 100 | 0.59 | Contact Map | 0.611 |
| 4io1A | 2 | 0.65 | 100 | 0.608 | Contact Map | 0.699 |
| 4gmkA | 2 | 0.6077 | 100 | 0.61 | Contact Map | 0.748 |
| 3l7oA | 2 | 0.5962 | 100 | 0.612 | Contact Map | 0.735 |
| 1o8bA | 2 | 0.6038 | 100 | 0.618 | Contact Map | 0.607 |
| 1uj6A | 1 | 0.6038 | 100 | 0.623 | Contact Map | 0.678 |
| 1lk5A | 4 | 0.6 | 100 | 0.624 | Contact Map | 0.758 |
| 1m0sA | 2 | 0.6038 | 100 | 0.624 | Contact Map | 0.734 |
Sequence Conservation (Image Generated using WebLogo v3)