| UniProt: | P76034 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13905 | ||
| Length: | 249 (246) | ||
| Sequences: | 3479 | ||
| Seq/Len: | 14.14 |
| YCIT
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 101_L | 200_L | 3.583 | 1.00 | |
| 88_E | 162_K | 3.244 | 1.00 | |
| 79_F | 82_S | 3.061 | 1.00 | |
| 163_A | 194_E | 2.769 | 1.00 | |
| 93_E | 187_V | 2.716 | 1.00 | |
| 131_E | 138_V | 2.559 | 1.00 | |
| 11_M | 26_A | 2.243 | 1.00 | |
| 162_K | 198_I | 2.167 | 1.00 | |
| 191_L | 215_G | 2.068 | 1.00 | |
| 103_R | 124_L | 2.021 | 1.00 | |
| 198_I | 222_R | 2.009 | 1.00 | |
| 91_F | 160_F | 2.006 | 1.00 | |
| 162_K | 196_E | 1.953 | 1.00 | |
| 213_S | 216_P | 1.924 | 1.00 | |
| 80_A | 164_F | 1.89 | 1.00 | |
| 80_A | 200_L | 1.885 | 1.00 | |
| 11_M | 15_Q | 1.884 | 1.00 | |
| 160_F | 190_V | 1.849 | 1.00 | |
| 23_L | 34_I | 1.849 | 1.00 | |
| 203_S | 226_D | 1.844 | 1.00 | |
| 115_I | 160_F | 1.842 | 1.00 | |
| 84_V | 105_L | 1.824 | 1.00 | |
| 222_R | 245_H | 1.81 | 1.00 | |
| 229_I | 234_L | 1.809 | 1.00 | |
| 91_F | 190_V | 1.798 | 1.00 | |
| 191_L | 197_A | 1.795 | 1.00 | |
| 78_E | 104_T | 1.774 | 1.00 | |
| 85_Q | 88_E | 1.754 | 1.00 | |
| 196_E | 222_R | 1.747 | 1.00 | |
| 92_I | 98_N | 1.737 | 1.00 | |
| 234_L | 238_E | 1.736 | 1.00 | |
| 114_I | 130_C | 1.73 | 1.00 | |
| 7_T | 10_Q | 1.714 | 1.00 | |
| 74_R | 100_L | 1.705 | 1.00 | |
| 216_P | 219_R | 1.705 | 1.00 | |
| 101_L | 164_F | 1.702 | 1.00 | |
| 88_E | 161_S | 1.693 | 1.00 | |
| 153_Q | 156_Q | 1.635 | 1.00 | |
| 100_L | 103_R | 1.628 | 1.00 | |
| 156_Q | 189_A | 1.623 | 1.00 | |
| 29_V | 34_I | 1.621 | 1.00 | |
| 81_A | 104_T | 1.621 | 1.00 | |
| 94_N | 145_S | 1.621 | 1.00 | |
| 135_L | 151_T | 1.613 | 1.00 | |
| 161_S | 195_C | 1.591 | 1.00 | |
| 69_N | 204_S | 1.591 | 1.00 | |
| 77_A | 104_T | 1.575 | 1.00 | |
| 122_A | 134_L | 1.545 | 1.00 | |
| 5_Q | 44_L | 1.537 | 1.00 | |
| 69_N | 72_L | 1.532 | 1.00 | |
| 134_L | 146_M | 1.531 | 1.00 | |
| 38_L | 54_A | 1.526 | 1.00 | |
| 9_L | 46_Y | 1.526 | 1.00 | |
| 17_Q | 55_V | 1.51 | 1.00 | |
| 9_L | 12_V | 1.509 | 1.00 | |
| 135_L | 154_C | 1.485 | 1.00 | |
| 7_T | 11_M | 1.447 | 1.00 | |
| 164_F | 198_I | 1.446 | 1.00 | |
| 153_Q | 157_Q | 1.444 | 1.00 | |
| 86_P | 109_K | 1.433 | 1.00 | |
| 139_Y | 146_M | 1.43 | 1.00 | |
| 176_F | 199_V | 1.43 | 1.00 | |
| 87_G | 111_N | 1.41 | 1.00 | |
| 83_L | 224_I | 1.398 | 0.99 | |
| 32_V | 36_Q | 1.395 | 0.99 | |
| 206_F | 223_V | 1.388 | 0.99 | |
| 189_A | 193_K | 1.387 | 0.99 | |
| 197_A | 220_F | 1.377 | 0.99 | |
| 235_M | 239_H | 1.36 | 0.99 | |
| 135_L | 146_M | 1.357 | 0.99 | |
| 15_Q | 22_D | 1.356 | 0.99 | |
| 189_A | 192_E | 1.343 | 0.99 | |
| 11_M | 18_V | 1.339 | 0.99 | |
| 199_V | 220_F | 1.338 | 0.99 | |
| 83_L | 198_I | 1.329 | 0.99 | |
| 6_Q | 10_Q | 1.322 | 0.99 | |
| 152_R | 185_D | 1.317 | 0.99 | |
| 81_A | 101_L | 1.302 | 0.99 | |
| 86_P | 108_Q | 1.297 | 0.99 | |
| 176_F | 220_F | 1.272 | 0.99 | |
| 196_E | 221_N | 1.271 | 0.99 | |
| 7_T | 27_T | 1.268 | 0.99 | |
| 156_Q | 192_E | 1.266 | 0.99 | |
| 74_R | 104_T | 1.259 | 0.99 | |
| 113_T | 133_I | 1.243 | 0.98 | |
| 50_A | 53_F | 1.239 | 0.98 | |
| 114_I | 125_L | 1.237 | 0.98 | |
| 230_R | 233_D | 1.23 | 0.98 | |
| 81_A | 84_V | 1.229 | 0.98 | |
| 77_A | 81_A | 1.227 | 0.98 | |
| 8_I | 23_L | 1.223 | 0.98 | |
| 169_G | 177_T | 1.213 | 0.98 | |
| 206_F | 229_I | 1.212 | 0.98 | |
| 170_W | 206_F | 1.199 | 0.98 | |
| 79_F | 245_H | 1.197 | 0.98 | |
| 138_V | 182_M | 1.184 | 0.98 | |
| 12_V | 47_L | 1.183 | 0.98 | |
| 73_K | 96_S | 1.182 | 0.98 | |
| 19_S | 22_D | 1.176 | 0.98 | |
| 167_I | 214_I | 1.173 | 0.98 | |
| 70_Y | 100_L | 1.17 | 0.97 | |
| 167_I | 199_V | 1.161 | 0.97 | |
| 151_T | 186_V | 1.161 | 0.97 | |
| 20_V | 38_L | 1.158 | 0.97 | |
| 47_L | 54_A | 1.157 | 0.97 | |
| 21_T | 31_E | 1.149 | 0.97 | |
| 95_G | 98_N | 1.142 | 0.97 | |
| 167_I | 201_T | 1.141 | 0.97 | |
| 170_W | 201_T | 1.135 | 0.97 | |
| 102_A | 125_L | 1.134 | 0.97 | |
| 18_V | 23_L | 1.13 | 0.97 | |
| 7_T | 26_A | 1.122 | 0.97 | |
| 86_P | 111_N | 1.116 | 0.96 | |
| 72_L | 226_D | 1.109 | 0.96 | |
| 80_A | 224_I | 1.101 | 0.96 | |
| 102_A | 124_L | 1.098 | 0.96 | |
| 113_T | 131_E | 1.096 | 0.96 | |
| 98_N | 101_L | 1.095 | 0.96 | |
| 11_M | 14_D | 1.095 | 0.96 | |
| 72_L | 203_S | 1.093 | 0.96 | |
| 235_M | 238_E | 1.074 | 0.95 | |
| 5_Q | 40_T | 1.071 | 0.95 | |
| 215_G | 219_R | 1.064 | 0.95 | |
| 198_I | 224_I | 1.058 | 0.95 | |
| 62_V | 96_S | 1.057 | 0.95 | |
| 97_S | 202_D | 1.056 | 0.95 | |
| 12_V | 56_S | 1.037 | 0.94 | |
| 76_L | 97_S | 1.033 | 0.94 | |
| 192_E | 219_R | 1.031 | 0.94 | |
| 203_S | 228_K | 1.018 | 0.93 | |
| 140_Q | 183_R | 1.016 | 0.93 | |
| 135_L | 155_I | 1.012 | 0.93 | |
| 73_K | 205_K | 1.011 | 0.93 | |
| 155_I | 189_A | 1.001 | 0.92 | |
| 80_A | 101_L | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9357 | 100 | 0.506 | Contact Map | 0.271 |
| 3rrlB | 2 | 0.6827 | 100 | 0.521 | Contact Map | 0.58 |
| 2w48A | 4 | 0.9357 | 100 | 0.587 | Contact Map | 0.599 |
| 4io1A | 2 | 0.6546 | 100 | 0.595 | Contact Map | 0.711 |
| 3l7oA | 2 | 0.6225 | 100 | 0.601 | Contact Map | 0.742 |
| 1o8bA | 2 | 0.6305 | 100 | 0.603 | Contact Map | 0.6 |
| 4gmkA | 2 | 0.6345 | 100 | 0.603 | Contact Map | 0.754 |
| 1m0sA | 2 | 0.6305 | 100 | 0.61 | Contact Map | 0.731 |
| 2o0mA | 1 | 0.9478 | 100 | 0.616 | Contact Map | 0.537 |
| 1lk5A | 4 | 0.6265 | 100 | 0.616 | Contact Map | 0.762 |
Sequence Conservation (Image Generated using WebLogo v3)