| UniProt: | P76114 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13773 | ||
| Length: | 221 (206) | ||
| Sequences: | 9927 | ||
| Seq/Len: | 48.19 |
| MCBR
Paralog alert: 0.80 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: CSIR DGOR EXUR FADR GLCC LLDR MCBR NANR PDHR UXUR YDFH YIEP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 113_Q | 193_K | 4.201 | 1.00 | |
| 98_A | 201_R | 3.259 | 1.00 | |
| 196_D | 199_G | 3.16 | 1.00 | |
| 30_K | 33_A | 3.143 | 1.00 | |
| 120_Q | 186_H | 2.935 | 1.00 | |
| 23_Q | 28_A | 2.68 | 1.00 | |
| 23_Q | 43_Q | 2.632 | 1.00 | |
| 84_E | 149_P | 2.521 | 1.00 | |
| 91_E | 95_M | 2.377 | 1.00 | |
| 17_E | 57_R | 2.309 | 1.00 | |
| 37_T | 48_I | 2.298 | 1.00 | |
| 16_V | 46_M | 2.11 | 1.00 | |
| 21_K | 61_V | 2.101 | 1.00 | |
| 16_V | 44_L | 2.011 | 1.00 | |
| 191_A | 199_G | 1.99 | 1.00 | |
| 105_T | 108_D | 1.987 | 1.00 | |
| 102_E | 197_K | 1.926 | 1.00 | |
| 111_E | 141_A | 1.913 | 1.00 | |
| 108_D | 147_N | 1.888 | 1.00 | |
| 109_L | 193_K | 1.883 | 1.00 | |
| 87_R | 99_L | 1.881 | 1.00 | |
| 127_D | 130_Q | 1.837 | 1.00 | |
| 66_V | 72_F | 1.79 | 1.00 | |
| 199_G | 203_C | 1.724 | 1.00 | |
| 65_S | 75_P | 1.702 | 1.00 | |
| 19_D | 23_Q | 1.671 | 1.00 | |
| 141_A | 144_H | 1.652 | 1.00 | |
| 22_H | 26_I | 1.623 | 1.00 | |
| 190_A | 194_A | 1.577 | 1.00 | |
| 40_L | 51_V | 1.576 | 1.00 | |
| 144_H | 152_C | 1.576 | 1.00 | |
| 90_Y | 209_Q | 1.548 | 1.00 | |
| 116_L | 189_L | 1.534 | 1.00 | |
| 139_R | 185_Y | 1.529 | 1.00 | |
| 88_I | 154_M | 1.518 | 1.00 | |
| 17_E | 61_V | 1.515 | 1.00 | |
| 140_L | 156_E | 1.5 | 1.00 | |
| 98_A | 198_E | 1.495 | 1.00 | |
| 94_L | 201_R | 1.476 | 1.00 | |
| 194_A | 199_G | 1.474 | 1.00 | |
| 201_R | 205_A | 1.445 | 1.00 | |
| 115_L | 134_V | 1.433 | 1.00 | |
| 98_A | 197_K | 1.427 | 1.00 | |
| 67_A | 70_Q | 1.417 | 1.00 | |
| 97_V | 101_V | 1.412 | 1.00 | |
| 10_V | 18_N | 1.378 | 0.99 | |
| 186_H | 190_A | 1.368 | 0.99 | |
| 118_K | 137_L | 1.358 | 0.99 | |
| 95_M | 98_A | 1.358 | 0.99 | |
| 84_E | 150_I | 1.338 | 0.99 | |
| 108_D | 145_R | 1.329 | 0.99 | |
| 135_N | 139_R | 1.311 | 0.99 | |
| 89_R | 93_E | 1.309 | 0.99 | |
| 104_L | 109_L | 1.295 | 0.99 | |
| 142_I | 192_L | 1.294 | 0.99 | |
| 39_N | 43_Q | 1.294 | 0.99 | |
| 19_D | 22_H | 1.29 | 0.99 | |
| 90_Y | 94_L | 1.288 | 0.99 | |
| 202_H | 206_E | 1.279 | 0.99 | |
| 153_E | 157_Q | 1.27 | 0.99 | |
| 143_Y | 155_I | 1.267 | 0.99 | |
| 114_E | 118_K | 1.263 | 0.99 | |
| 94_L | 205_A | 1.262 | 0.99 | |
| 97_V | 200_C | 1.25 | 0.99 | |
| 97_V | 204_L | 1.247 | 0.99 | |
| 197_K | 201_R | 1.246 | 0.98 | |
| 104_L | 195_K | 1.245 | 0.98 | |
| 38_K | 42_E | 1.24 | 0.98 | |
| 84_E | 148_M | 1.224 | 0.98 | |
| 36_I | 39_N | 1.217 | 0.98 | |
| 146_S | 152_C | 1.21 | 0.98 | |
| 199_G | 202_H | 1.206 | 0.98 | |
| 113_Q | 117_E | 1.19 | 0.98 | |
| 118_K | 134_V | 1.187 | 0.98 | |
| 23_Q | 44_L | 1.181 | 0.98 | |
| 87_R | 103_N | 1.18 | 0.98 | |
| 113_Q | 189_L | 1.179 | 0.98 | |
| 104_L | 145_R | 1.177 | 0.98 | |
| 96_A | 143_Y | 1.173 | 0.98 | |
| 111_E | 144_H | 1.169 | 0.97 | |
| 104_L | 192_L | 1.16 | 0.97 | |
| 59_V | 66_V | 1.159 | 0.97 | |
| 141_A | 145_R | 1.157 | 0.97 | |
| 15_Q | 19_D | 1.157 | 0.97 | |
| 67_A | 73_T | 1.155 | 0.97 | |
| 137_L | 141_A | 1.15 | 0.97 | |
| 94_L | 98_A | 1.148 | 0.97 | |
| 59_V | 64_L | 1.134 | 0.97 | |
| 55_L | 64_L | 1.134 | 0.97 | |
| 87_R | 148_M | 1.133 | 0.97 | |
| 189_L | 193_K | 1.131 | 0.97 | |
| 184_N | 207_I | 1.13 | 0.97 | |
| 19_D | 44_L | 1.129 | 0.97 | |
| 24_L | 74_V | 1.125 | 0.97 | |
| 90_Y | 205_A | 1.123 | 0.97 | |
| 109_L | 195_K | 1.119 | 0.96 | |
| 109_L | 189_L | 1.117 | 0.96 | |
| 191_A | 196_D | 1.117 | 0.96 | |
| 150_I | 161_R | 1.114 | 0.96 | |
| 138_F | 189_L | 1.086 | 0.96 | |
| 115_L | 141_A | 1.073 | 0.95 | |
| 187_L | 203_C | 1.073 | 0.95 | |
| 188_L | 204_L | 1.067 | 0.95 | |
| 104_L | 108_D | 1.054 | 0.95 | |
| 187_L | 199_G | 1.053 | 0.95 | |
| 140_L | 144_H | 1.049 | 0.94 | |
| 53_E | 56_L | 1.047 | 0.94 | |
| 34_R | 73_T | 1.045 | 0.94 | |
| 117_E | 121_Q | 1.044 | 0.94 | |
| 101_V | 197_K | 1.031 | 0.94 | |
| 70_Q | 73_T | 1.022 | 0.93 | |
| 21_K | 63_A | 1.018 | 0.93 | |
| 117_E | 120_Q | 1.016 | 0.93 | |
| 106_P | 195_K | 1.016 | 0.93 | |
| 17_E | 21_K | 1.013 | 0.93 | |
| 29_L | 74_V | 1.013 | 0.93 | |
| 64_L | 72_F | 1.011 | 0.93 | |
| 78_G | 81_Q | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3sxyA | 2 | 0.9548 | 100 | 0.123 | Contact Map | 0.779 |
| 3ihuA | 2 | 0.9774 | 100 | 0.128 | Contact Map | 0.652 |
| 2hs5A | 1 | 0.9774 | 100 | 0.129 | Contact Map | 0.588 |
| 3c7jA | 2 | 0.9774 | 100 | 0.14 | Contact Map | 0.792 |
| 2di3A | 2 | 0.9502 | 100 | 0.183 | Contact Map | 0.659 |
| 1hw1A | 2 | 0.9457 | 100 | 0.205 | Contact Map | 0.653 |
| 4hamA | 1 | 0.5747 | 99.9 | 0.513 | Contact Map | 0.692 |
| 3ic7A | 2 | 0.552 | 99.9 | 0.523 | Contact Map | 0.664 |
| 3by6A | 5 | 0.5611 | 99.9 | 0.543 | Contact Map | 0.844 |
| 3neuA | 1 | 0.543 | 99.8 | 0.561 | Contact Map | 0.655 |
Sequence Conservation (Image Generated using WebLogo v3)