| UniProt: | P0ACM2 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13820 | ||
| Length: | 228 (208) | ||
| Sequences: | 9910 | ||
| Seq/Len: | 47.64 |
| YDFH
Paralog alert: 0.80 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: CSIR DGOR EXUR FADR GLCC LLDR MCBR NANR PDHR UXUR YDFH YIEP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 114_E | 192_Q | 4.171 | 1.00 | |
| 99_R | 200_E | 3.324 | 1.00 | |
| 195_D | 198_A | 3.142 | 1.00 | |
| 31_A | 34_T | 3.095 | 1.00 | |
| 121_R | 185_L | 2.946 | 1.00 | |
| 24_D | 29_L | 2.627 | 1.00 | |
| 24_D | 44_R | 2.616 | 1.00 | |
| 85_N | 150_Q | 2.371 | 1.00 | |
| 92_A | 96_A | 2.359 | 1.00 | |
| 18_Y | 58_K | 2.276 | 1.00 | |
| 38_E | 49_R | 2.269 | 1.00 | |
| 17_I | 47_V | 2.111 | 1.00 | |
| 22_R | 62_N | 2.067 | 1.00 | |
| 106_T | 109_Q | 2.033 | 1.00 | |
| 17_I | 45_F | 2.022 | 1.00 | |
| 91_Q | 208_Q | 1.992 | 1.00 | |
| 190_A | 198_A | 1.963 | 1.00 | |
| 103_S | 196_G | 1.904 | 1.00 | |
| 109_Q | 148_D | 1.831 | 1.00 | |
| 112_Q | 142_L | 1.828 | 1.00 | |
| 128_Q | 131_D | 1.827 | 1.00 | |
| 198_A | 202_A | 1.806 | 1.00 | |
| 67_I | 73_S | 1.796 | 1.00 | |
| 110_C | 192_Q | 1.792 | 1.00 | |
| 88_F | 100_R | 1.764 | 1.00 | |
| 66_Q | 76_N | 1.635 | 1.00 | |
| 142_L | 145_Q | 1.619 | 1.00 | |
| 23_R | 27_H | 1.614 | 1.00 | |
| 20_I | 24_D | 1.599 | 1.00 | |
| 41_V | 52_V | 1.548 | 1.00 | |
| 189_S | 193_K | 1.544 | 1.00 | |
| 140_H | 184_H | 1.539 | 1.00 | |
| 200_E | 204_T | 1.539 | 1.00 | |
| 145_Q | 153_W | 1.53 | 1.00 | |
| 117_L | 188_F | 1.516 | 1.00 | |
| 99_R | 197_D | 1.494 | 1.00 | |
| 95_C | 200_E | 1.491 | 1.00 | |
| 89_I | 155_T | 1.484 | 1.00 | |
| 18_Y | 62_N | 1.462 | 1.00 | |
| 141_Q | 157_E | 1.452 | 1.00 | |
| 201_R | 205_Q | 1.433 | 1.00 | |
| 68_R | 71_R | 1.43 | 1.00 | |
| 185_L | 189_S | 1.428 | 1.00 | |
| 193_K | 198_A | 1.424 | 1.00 | |
| 116_N | 135_L | 1.417 | 1.00 | |
| 95_C | 204_T | 1.382 | 0.99 | |
| 98_A | 102_A | 1.368 | 0.99 | |
| 183_Q | 206_H | 1.367 | 0.99 | |
| 11_Q | 19_R | 1.357 | 0.99 | |
| 96_A | 99_R | 1.356 | 0.99 | |
| 99_R | 196_G | 1.355 | 0.99 | |
| 98_A | 203_M | 1.328 | 0.99 | |
| 143_L | 191_L | 1.326 | 0.99 | |
| 115_Q | 119_Q | 1.32 | 0.99 | |
| 109_Q | 146_I | 1.315 | 0.99 | |
| 105_I | 110_C | 1.313 | 0.99 | |
| 85_N | 151_L | 1.304 | 0.99 | |
| 119_Q | 138_N | 1.304 | 0.99 | |
| 40_E | 44_R | 1.295 | 0.99 | |
| 196_G | 200_E | 1.286 | 0.99 | |
| 198_A | 201_R | 1.286 | 0.99 | |
| 114_E | 118_H | 1.279 | 0.99 | |
| 98_A | 199_V | 1.266 | 0.99 | |
| 105_I | 194_R | 1.262 | 0.99 | |
| 20_I | 23_R | 1.254 | 0.99 | |
| 154_D | 158_N | 1.251 | 0.99 | |
| 91_Q | 95_C | 1.242 | 0.98 | |
| 183_Q | 209_E | 1.23 | 0.98 | |
| 144_T | 156_I | 1.227 | 0.98 | |
| 91_Q | 204_T | 1.227 | 0.98 | |
| 186_D | 202_A | 1.224 | 0.98 | |
| 147_A | 153_W | 1.213 | 0.98 | |
| 85_N | 149_C | 1.209 | 0.98 | |
| 39_K | 43_V | 1.209 | 0.98 | |
| 90_R | 94_E | 1.204 | 0.98 | |
| 136_D | 140_H | 1.203 | 0.98 | |
| 138_N | 142_L | 1.198 | 0.98 | |
| 97_V | 144_T | 1.198 | 0.98 | |
| 68_R | 74_Y | 1.194 | 0.98 | |
| 24_D | 45_F | 1.192 | 0.98 | |
| 105_I | 146_I | 1.174 | 0.98 | |
| 105_I | 191_L | 1.163 | 0.97 | |
| 37_S | 40_E | 1.163 | 0.97 | |
| 114_E | 188_F | 1.16 | 0.97 | |
| 110_C | 194_R | 1.156 | 0.97 | |
| 16_Q | 20_I | 1.146 | 0.97 | |
| 119_Q | 135_L | 1.13 | 0.97 | |
| 188_F | 192_Q | 1.127 | 0.97 | |
| 56_F | 65_I | 1.124 | 0.97 | |
| 60_A | 65_I | 1.124 | 0.97 | |
| 60_A | 67_I | 1.123 | 0.97 | |
| 112_Q | 145_Q | 1.122 | 0.97 | |
| 187_I | 203_M | 1.121 | 0.97 | |
| 95_C | 99_R | 1.119 | 0.96 | |
| 187_I | 202_A | 1.116 | 0.96 | |
| 25_I | 75_V | 1.111 | 0.96 | |
| 110_C | 188_F | 1.107 | 0.96 | |
| 142_L | 146_I | 1.106 | 0.96 | |
| 20_I | 45_F | 1.105 | 0.96 | |
| 190_A | 195_D | 1.093 | 0.96 | |
| 35_P | 74_Y | 1.082 | 0.96 | |
| 186_D | 198_A | 1.072 | 0.95 | |
| 102_A | 196_G | 1.056 | 0.95 | |
| 139_F | 188_F | 1.056 | 0.95 | |
| 91_Q | 211_S | 1.055 | 0.95 | |
| 116_N | 142_L | 1.053 | 0.95 | |
| 88_F | 104_M | 1.051 | 0.94 | |
| 105_I | 109_Q | 1.048 | 0.94 | |
| 141_Q | 145_Q | 1.043 | 0.94 | |
| 118_H | 121_R | 1.041 | 0.94 | |
| 184_H | 206_H | 1.034 | 0.94 | |
| 107_E | 194_R | 1.033 | 0.94 | |
| 117_L | 120_Q | 1.031 | 0.94 | |
| 186_D | 205_Q | 1.027 | 0.94 | |
| 54_E | 57_I | 1.019 | 0.93 | |
| 18_Y | 22_R | 1.017 | 0.93 | |
| 22_R | 64_L | 1.008 | 0.93 | |
| 189_S | 192_Q | 1.002 | 0.92 | |
| 204_T | 208_Q | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3sxyA | 2 | 0.943 | 100 | 0.2 | Contact Map | 0.775 |
| 2hs5A | 1 | 0.9737 | 100 | 0.204 | Contact Map | 0.6 |
| 3ihuA | 2 | 0.9518 | 100 | 0.209 | Contact Map | 0.664 |
| 3c7jA | 2 | 0.9737 | 100 | 0.218 | Contact Map | 0.789 |
| 1hw1A | 2 | 0.9518 | 100 | 0.223 | Contact Map | 0.64 |
| 2di3A | 2 | 0.9342 | 100 | 0.248 | Contact Map | 0.664 |
| 4hamA | 1 | 0.5614 | 99.9 | 0.556 | Contact Map | 0.696 |
| 3ic7A | 2 | 0.5307 | 99.8 | 0.582 | Contact Map | 0.643 |
| 3by6A | 5 | 0.5395 | 99.8 | 0.585 | Contact Map | 0.839 |
| 1ulyA | 1 | 0.7149 | 99.8 | 0.599 | Contact Map | 0.275 |
Sequence Conservation (Image Generated using WebLogo v3)