| UniProt: | P31475 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11733 | ||
| Length: | 230 (219) | ||
| Sequences: | 9944 | ||
| Seq/Len: | 45.41 |
| YIEP
Paralog alert: 0.80 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: CSIR DGOR EXUR FADR GLCC LLDR MCBR NANR PDHR UXUR YDFH YIEP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 135_N | 210_I | 4.374 | 1.00 | |
| 120_L | 218_F | 3.467 | 1.00 | |
| 213_D | 216_A | 3.2 | 1.00 | |
| 32_E | 35_T | 3.184 | 1.00 | |
| 142_A | 203_Q | 3.061 | 1.00 | |
| 25_R | 30_E | 2.698 | 1.00 | |
| 25_R | 46_Q | 2.673 | 1.00 | |
| 106_H | 171_P | 2.64 | 1.00 | |
| 40_E | 51_R | 2.408 | 1.00 | |
| 113_C | 117_Q | 2.344 | 1.00 | |
| 19_A | 60_T | 2.277 | 1.00 | |
| 23_A | 64_K | 2.174 | 1.00 | |
| 18_L | 49_V | 2.161 | 1.00 | |
| 18_L | 47_F | 2.125 | 1.00 | |
| 127_T | 130_Q | 2.088 | 1.00 | |
| 208_A | 216_A | 2.065 | 1.00 | |
| 112_I | 226_R | 1.98 | 1.00 | |
| 124_T | 214_G | 1.975 | 1.00 | |
| 133_H | 163_H | 1.94 | 1.00 | |
| 130_Q | 169_A | 1.927 | 1.00 | |
| 216_A | 220_A | 1.9 | 1.00 | |
| 109_V | 121_L | 1.88 | 1.00 | |
| 131_K | 210_I | 1.878 | 1.00 | |
| 149_R | 152_R | 1.874 | 1.00 | |
| 69_P | 75_T | 1.791 | 1.00 | |
| 68_L | 78_M | 1.737 | 1.00 | |
| 24_Q | 28_K | 1.668 | 1.00 | |
| 161_H | 202_H | 1.658 | 1.00 | |
| 163_H | 166_E | 1.657 | 1.00 | |
| 207_D | 211_Q | 1.623 | 1.00 | |
| 120_L | 215_D | 1.612 | 1.00 | |
| 21_K | 25_R | 1.569 | 1.00 | |
| 138_M | 206_V | 1.564 | 1.00 | |
| 166_E | 174_T | 1.559 | 1.00 | |
| 116_P | 218_F | 1.551 | 1.00 | |
| 110_M | 176_F | 1.55 | 1.00 | |
| 43_L | 54_V | 1.54 | 1.00 | |
| 218_F | 222_Q | 1.536 | 1.00 | |
| 137_L | 156_V | 1.528 | 1.00 | |
| 219_K | 223_A | 1.461 | 1.00 | |
| 211_Q | 216_A | 1.458 | 1.00 | |
| 201_L | 224_L | 1.452 | 1.00 | |
| 162_E | 178_S | 1.44 | 1.00 | |
| 119_C | 123_A | 1.434 | 1.00 | |
| 119_C | 221_C | 1.428 | 1.00 | |
| 140_E | 159_A | 1.42 | 1.00 | |
| 203_Q | 207_D | 1.415 | 1.00 | |
| 70_R | 73_I | 1.413 | 1.00 | |
| 120_L | 214_G | 1.413 | 1.00 | |
| 12_K | 20_E | 1.411 | 1.00 | |
| 116_P | 222_Q | 1.403 | 0.99 | |
| 106_H | 172_F | 1.394 | 0.99 | |
| 126_G | 131_K | 1.392 | 0.99 | |
| 19_A | 64_K | 1.384 | 0.99 | |
| 117_Q | 120_L | 1.371 | 0.99 | |
| 42_E | 46_Q | 1.356 | 0.99 | |
| 216_A | 219_K | 1.352 | 0.99 | |
| 119_C | 217_A | 1.343 | 0.99 | |
| 164_I | 209_I | 1.343 | 0.99 | |
| 168_S | 174_T | 1.343 | 0.99 | |
| 130_Q | 167_M | 1.33 | 0.99 | |
| 214_G | 218_F | 1.323 | 0.99 | |
| 21_K | 24_Q | 1.311 | 0.99 | |
| 112_I | 116_P | 1.31 | 0.99 | |
| 112_I | 222_Q | 1.295 | 0.99 | |
| 126_G | 212_S | 1.29 | 0.99 | |
| 126_G | 209_I | 1.277 | 0.99 | |
| 157_D | 161_H | 1.261 | 0.99 | |
| 136_T | 140_E | 1.258 | 0.99 | |
| 106_H | 170_N | 1.253 | 0.99 | |
| 165_Y | 177_A | 1.25 | 0.99 | |
| 111_R | 115_E | 1.25 | 0.99 | |
| 118_A | 165_Y | 1.244 | 0.98 | |
| 126_G | 167_M | 1.24 | 0.98 | |
| 70_R | 76_R | 1.227 | 0.98 | |
| 204_A | 220_A | 1.226 | 0.98 | |
| 25_R | 47_F | 1.224 | 0.98 | |
| 159_A | 163_H | 1.218 | 0.98 | |
| 135_N | 206_V | 1.216 | 0.98 | |
| 41_I | 45_E | 1.215 | 0.98 | |
| 109_V | 125_V | 1.213 | 0.98 | |
| 133_H | 166_E | 1.208 | 0.98 | |
| 135_N | 139_A | 1.191 | 0.98 | |
| 109_V | 170_N | 1.186 | 0.98 | |
| 21_K | 47_F | 1.186 | 0.98 | |
| 205_I | 221_C | 1.163 | 0.97 | |
| 17_V | 21_K | 1.162 | 0.97 | |
| 205_I | 220_A | 1.162 | 0.97 | |
| 131_K | 206_V | 1.158 | 0.97 | |
| 206_V | 210_I | 1.155 | 0.97 | |
| 175_S | 179_L | 1.153 | 0.97 | |
| 163_H | 167_M | 1.152 | 0.97 | |
| 131_K | 212_S | 1.147 | 0.97 | |
| 58_V | 67_V | 1.143 | 0.97 | |
| 116_P | 120_L | 1.141 | 0.97 | |
| 62_T | 67_V | 1.134 | 0.97 | |
| 62_T | 69_P | 1.133 | 0.97 | |
| 140_E | 156_V | 1.132 | 0.97 | |
| 201_L | 227_S | 1.132 | 0.97 | |
| 26_I | 77_V | 1.12 | 0.96 | |
| 126_G | 130_Q | 1.117 | 0.96 | |
| 202_H | 224_L | 1.108 | 0.96 | |
| 123_A | 214_G | 1.107 | 0.96 | |
| 204_A | 216_A | 1.106 | 0.96 | |
| 128_A | 212_S | 1.104 | 0.96 | |
| 208_A | 213_D | 1.094 | 0.96 | |
| 137_L | 163_H | 1.092 | 0.96 | |
| 56_E | 59_K | 1.091 | 0.96 | |
| 39_G | 42_E | 1.088 | 0.96 | |
| 31_Y | 77_V | 1.075 | 0.95 | |
| 67_V | 75_T | 1.064 | 0.95 | |
| 162_E | 166_E | 1.064 | 0.95 | |
| 139_A | 143_A | 1.062 | 0.95 | |
| 160_W | 206_V | 1.053 | 0.95 | |
| 139_A | 142_A | 1.044 | 0.94 | |
| 36_I | 76_R | 1.039 | 0.94 | |
| 73_I | 76_R | 1.038 | 0.94 | |
| 204_A | 223_A | 1.035 | 0.94 | |
| 143_A | 147_N | 1.031 | 0.94 | |
| 138_M | 203_Q | 1.02 | 0.93 | |
| 215_D | 219_K | 1.02 | 0.93 | |
| 19_A | 23_A | 1.02 | 0.93 | |
| 68_L | 76_R | 1.009 | 0.93 | |
| 123_A | 212_S | 1.004 | 0.93 | |
| 161_H | 224_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3ihuA | 2 | 0.913 | 100 | 0.158 | Contact Map | 0.647 |
| 3sxyA | 2 | 0.8913 | 100 | 0.172 | Contact Map | 0.775 |
| 2hs5A | 1 | 0.9043 | 100 | 0.181 | Contact Map | 0.582 |
| 3c7jA | 2 | 0.9 | 100 | 0.185 | Contact Map | 0.793 |
| 2di3A | 2 | 0.9261 | 100 | 0.2 | Contact Map | 0.67 |
| 1hw1A | 2 | 0.9391 | 100 | 0.222 | Contact Map | 0.648 |
| 4hamA | 1 | 0.5739 | 99.9 | 0.516 | Contact Map | 0.697 |
| 3ic7A | 2 | 0.5348 | 99.9 | 0.531 | Contact Map | 0.661 |
| 3by6A | 5 | 0.5478 | 99.9 | 0.538 | Contact Map | 0.842 |
| 3neuA | 1 | 0.5435 | 99.8 | 0.563 | Contact Map | 0.665 |
Sequence Conservation (Image Generated using WebLogo v3)