| UniProt: | P0ACL9 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11088 | ||
| Length: | 254 (230) | ||
| Sequences: | 9491 | ||
| Seq/Len: | 41.27 |
| PDHR
Paralog alert: 0.78 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: CSIR DGOR EXUR FADR GLCC LLDR MCBR NANR PDHR UXUR YDFH YIEP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 128_R | 210_M | 4.514 | 1.00 | |
| 113_Y | 218_R | 3.492 | 1.00 | |
| 213_K | 216_E | 3.323 | 1.00 | |
| 29_R | 32_E | 3.272 | 1.00 | |
| 134_I | 203_T | 2.746 | 1.00 | |
| 22_L | 43_Q | 2.735 | 1.00 | |
| 22_L | 27_T | 2.735 | 1.00 | |
| 99_D | 164_V | 2.73 | 1.00 | |
| 37_E | 48_R | 2.418 | 1.00 | |
| 16_E | 57_R | 2.376 | 1.00 | |
| 106_A | 110_I | 2.363 | 1.00 | |
| 15_I | 46_V | 2.262 | 1.00 | |
| 15_I | 44_F | 2.183 | 1.00 | |
| 20_E | 61_K | 2.18 | 1.00 | |
| 208_A | 216_E | 2.138 | 1.00 | |
| 120_T | 123_D | 2.132 | 1.00 | |
| 105_H | 226_A | 2.078 | 1.00 | |
| 123_D | 162_H | 2 | 1.00 | |
| 142_D | 145_A | 1.976 | 1.00 | |
| 117_L | 214_P | 1.964 | 1.00 | |
| 216_E | 220_A | 1.938 | 1.00 | |
| 126_R | 156_A | 1.936 | 1.00 | |
| 124_K | 210_M | 1.903 | 1.00 | |
| 102_E | 114_Y | 1.839 | 1.00 | |
| 66_R | 72_T | 1.833 | 1.00 | |
| 65_L | 75_Q | 1.718 | 1.00 | |
| 21_F | 25_E | 1.702 | 1.00 | |
| 156_A | 159_E | 1.685 | 1.00 | |
| 113_Y | 215_E | 1.66 | 1.00 | |
| 154_Q | 202_R | 1.65 | 1.00 | |
| 207_E | 211_A | 1.645 | 1.00 | |
| 131_H | 206_F | 1.632 | 1.00 | |
| 159_E | 167_L | 1.602 | 1.00 | |
| 218_R | 222_H | 1.587 | 1.00 | |
| 18_Q | 22_L | 1.585 | 1.00 | |
| 103_T | 169_L | 1.579 | 1.00 | |
| 130_L | 149_A | 1.572 | 1.00 | |
| 155_I | 171_R | 1.567 | 1.00 | |
| 109_G | 218_R | 1.554 | 1.00 | |
| 40_L | 51_L | 1.551 | 1.00 | |
| 201_H | 224_H | 1.523 | 1.00 | |
| 211_A | 216_E | 1.523 | 1.00 | |
| 9_P | 17_Q | 1.514 | 1.00 | |
| 112_A | 116_A | 1.477 | 1.00 | |
| 219_E | 223_R | 1.47 | 1.00 | |
| 99_D | 165_V | 1.464 | 1.00 | |
| 67_R | 70_G | 1.453 | 1.00 | |
| 203_T | 207_E | 1.449 | 1.00 | |
| 113_Y | 214_P | 1.426 | 1.00 | |
| 109_G | 222_H | 1.425 | 1.00 | |
| 112_A | 221_S | 1.42 | 1.00 | |
| 214_P | 218_R | 1.415 | 1.00 | |
| 110_I | 113_Y | 1.412 | 1.00 | |
| 133_A | 152_Q | 1.407 | 0.99 | |
| 161_A | 167_L | 1.379 | 0.99 | |
| 216_E | 219_E | 1.379 | 0.99 | |
| 16_E | 61_K | 1.375 | 0.99 | |
| 112_A | 217_A | 1.369 | 0.99 | |
| 119_S | 209_I | 1.364 | 0.99 | |
| 119_S | 124_K | 1.359 | 0.99 | |
| 157_V | 209_I | 1.352 | 0.99 | |
| 119_S | 212_G | 1.349 | 0.99 | |
| 123_D | 160_A | 1.347 | 0.99 | |
| 18_Q | 21_F | 1.337 | 0.99 | |
| 158_T | 170_L | 1.334 | 0.99 | |
| 104_R | 108_E | 1.307 | 0.99 | |
| 39_E | 43_Q | 1.301 | 0.99 | |
| 105_H | 109_G | 1.299 | 0.99 | |
| 99_D | 163_N | 1.279 | 0.99 | |
| 38_R | 42_K | 1.269 | 0.99 | |
| 102_E | 118_R | 1.268 | 0.99 | |
| 129_E | 133_A | 1.265 | 0.99 | |
| 119_S | 160_A | 1.259 | 0.99 | |
| 111_A | 158_T | 1.259 | 0.99 | |
| 204_R | 220_A | 1.257 | 0.99 | |
| 105_H | 222_H | 1.25 | 0.99 | |
| 126_R | 159_E | 1.242 | 0.98 | |
| 128_R | 206_F | 1.239 | 0.98 | |
| 55_I | 64_L | 1.232 | 0.98 | |
| 168_H | 172_C | 1.226 | 0.98 | |
| 22_L | 44_F | 1.224 | 0.98 | |
| 152_Q | 156_A | 1.222 | 0.98 | |
| 201_H | 227_F | 1.216 | 0.98 | |
| 67_R | 73_F | 1.216 | 0.98 | |
| 128_R | 132_H | 1.203 | 0.98 | |
| 18_Q | 44_F | 1.194 | 0.98 | |
| 124_K | 206_F | 1.192 | 0.98 | |
| 14_V | 18_Q | 1.191 | 0.98 | |
| 121_D | 212_G | 1.19 | 0.98 | |
| 23_I | 74_V | 1.178 | 0.98 | |
| 109_G | 113_Y | 1.175 | 0.98 | |
| 150_V | 154_Q | 1.174 | 0.98 | |
| 205_I | 221_S | 1.168 | 0.97 | |
| 102_E | 163_N | 1.167 | 0.97 | |
| 204_R | 216_E | 1.166 | 0.97 | |
| 206_F | 210_M | 1.158 | 0.97 | |
| 124_K | 212_G | 1.158 | 0.97 | |
| 205_I | 220_A | 1.157 | 0.97 | |
| 59_E | 64_L | 1.156 | 0.97 | |
| 156_A | 160_A | 1.153 | 0.97 | |
| 105_H | 229_E | 1.145 | 0.97 | |
| 153_Y | 206_F | 1.139 | 0.97 | |
| 202_R | 224_H | 1.127 | 0.97 | |
| 59_E | 66_R | 1.124 | 0.97 | |
| 130_L | 156_A | 1.12 | 0.96 | |
| 119_S | 123_D | 1.12 | 0.96 | |
| 64_L | 72_T | 1.109 | 0.96 | |
| 116_A | 214_P | 1.103 | 0.96 | |
| 53_E | 56_Q | 1.092 | 0.96 | |
| 208_A | 213_K | 1.091 | 0.96 | |
| 70_G | 73_F | 1.086 | 0.96 | |
| 28_L | 74_V | 1.086 | 0.96 | |
| 155_I | 159_E | 1.085 | 0.96 | |
| 33_K | 73_F | 1.074 | 0.95 | |
| 204_R | 223_R | 1.07 | 0.95 | |
| 165_V | 176_M | 1.056 | 0.95 | |
| 16_E | 20_E | 1.051 | 0.94 | |
| 36_P | 39_E | 1.049 | 0.94 | |
| 20_E | 63_L | 1.047 | 0.94 | |
| 95_E | 99_D | 1.046 | 0.94 | |
| 154_Q | 224_H | 1.04 | 0.94 | |
| 131_H | 203_T | 1.037 | 0.94 | |
| 116_A | 212_G | 1.036 | 0.94 | |
| 148_N | 152_Q | 1.035 | 0.94 | |
| 222_H | 226_A | 1.031 | 0.94 | |
| 215_E | 219_E | 1.023 | 0.93 | |
| 65_L | 73_F | 1.02 | 0.93 | |
| 46_V | 51_L | 1.018 | 0.93 | |
| 127_I | 156_A | 1.014 | 0.93 | |
| 116_A | 217_A | 1.003 | 0.93 | |
| 133_A | 149_A | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3sxyA | 2 | 0.8425 | 100 | 0.236 | Contact Map | 0.787 |
| 3c7jA | 2 | 0.8661 | 100 | 0.241 | Contact Map | 0.798 |
| 3ihuA | 2 | 0.8425 | 100 | 0.243 | Contact Map | 0.655 |
| 2hs5A | 1 | 0.8661 | 100 | 0.247 | Contact Map | 0.587 |
| 2di3A | 2 | 0.9252 | 100 | 0.247 | Contact Map | 0.657 |
| 1hw1A | 2 | 0.9252 | 100 | 0.284 | Contact Map | 0.643 |
| 4hamA | 1 | 0.4961 | 99.9 | 0.564 | Contact Map | 0.705 |
| 3by6A | 5 | 0.4921 | 99.9 | 0.585 | Contact Map | 0.839 |
| 3ic7A | 2 | 0.4764 | 99.9 | 0.586 | Contact Map | 0.646 |
| 3neuA | 1 | 0.4803 | 99.8 | 0.596 | Contact Map | 0.674 |
Sequence Conservation (Image Generated using WebLogo v3)