| UniProt: | P0ACL7 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11962 | ||
| Length: | 258 (224) | ||
| Sequences: | 8945 | ||
| Seq/Len: | 39.93 |
| LLDR
Paralog alert: 0.78 [within 20: 0.19] - ratio of genomes with paralogs Cluster includes: CSIR DGOR EXUR FADR GLCC LLDR MCBR NANR PDHR UXUR YDFH YIEP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 129_Q | 207_F | 4.556 | 1.00 | |
| 114_W | 215_R | 3.521 | 1.00 | |
| 210_D | 213_G | 3.331 | 1.00 | |
| 26_E | 29_M | 3.321 | 1.00 | |
| 19_L | 40_Q | 2.745 | 1.00 | |
| 100_D | 161_I | 2.738 | 1.00 | |
| 19_L | 24_N | 2.73 | 1.00 | |
| 34_E | 45_R | 2.402 | 1.00 | |
| 107_A | 111_S | 2.347 | 1.00 | |
| 13_A | 54_K | 2.345 | 1.00 | |
| 12_V | 43_V | 2.257 | 1.00 | |
| 17_R | 58_E | 2.24 | 1.00 | |
| 205_A | 213_G | 2.181 | 1.00 | |
| 12_V | 41_L | 2.164 | 1.00 | |
| 121_T | 124_D | 2.141 | 1.00 | |
| 124_D | 159_H | 2.052 | 1.00 | |
| 118_M | 211_A | 2.021 | 1.00 | |
| 106_Y | 223_S | 1.98 | 1.00 | |
| 125_K | 207_F | 1.959 | 1.00 | |
| 139_D | 142_I | 1.954 | 1.00 | |
| 127_K | 153_A | 1.928 | 1.00 | |
| 213_G | 217_A | 1.927 | 1.00 | |
| 63_S | 69_T | 1.862 | 1.00 | |
| 103_E | 115_H | 1.819 | 1.00 | |
| 153_A | 156_E | 1.686 | 1.00 | |
| 132_F | 203_I | 1.685 | 1.00 | |
| 114_W | 212_D | 1.669 | 1.00 | |
| 18_A | 22_E | 1.665 | 1.00 | |
| 215_R | 219_M | 1.663 | 1.00 | |
| 204_D | 208_A | 1.616 | 1.00 | |
| 151_H | 199_H | 1.61 | 1.00 | |
| 37_L | 48_L | 1.606 | 1.00 | |
| 131_C | 146_A | 1.606 | 1.00 | |
| 156_E | 164_L | 1.604 | 1.00 | |
| 15_R | 19_L | 1.552 | 1.00 | |
| 152_L | 168_R | 1.55 | 1.00 | |
| 62_L | 74_R | 1.536 | 1.00 | |
| 110_A | 215_R | 1.531 | 1.00 | |
| 198_Q | 221_H | 1.528 | 1.00 | |
| 104_A | 166_T | 1.512 | 1.00 | |
| 216_K | 220_A | 1.496 | 1.00 | |
| 208_A | 213_G | 1.476 | 1.00 | |
| 113_A | 117_A | 1.436 | 1.00 | |
| 110_A | 219_M | 1.427 | 1.00 | |
| 113_A | 218_M | 1.423 | 1.00 | |
| 136_L | 200_Q | 1.422 | 1.00 | |
| 114_W | 211_A | 1.419 | 1.00 | |
| 6_R | 14_D | 1.411 | 1.00 | |
| 200_Q | 204_D | 1.404 | 0.99 | |
| 100_D | 162_V | 1.399 | 0.99 | |
| 113_A | 214_A | 1.399 | 0.99 | |
| 120_A | 209_G | 1.399 | 0.99 | |
| 15_R | 18_A | 1.395 | 0.99 | |
| 111_S | 114_W | 1.389 | 0.99 | |
| 13_A | 58_E | 1.388 | 0.99 | |
| 213_G | 216_K | 1.381 | 0.99 | |
| 64_R | 67_G | 1.38 | 0.99 | |
| 120_A | 125_K | 1.371 | 0.99 | |
| 211_A | 215_R | 1.369 | 0.99 | |
| 36_Q | 40_Q | 1.364 | 0.99 | |
| 154_I | 206_I | 1.359 | 0.99 | |
| 158_S | 164_L | 1.356 | 0.99 | |
| 124_D | 157_A | 1.346 | 0.99 | |
| 103_E | 119_R | 1.345 | 0.99 | |
| 120_A | 206_I | 1.344 | 0.99 | |
| 112_T | 155_A | 1.304 | 0.99 | |
| 106_Y | 110_A | 1.291 | 0.99 | |
| 100_D | 160_N | 1.282 | 0.99 | |
| 155_A | 167_M | 1.274 | 0.99 | |
| 105_R | 109_E | 1.262 | 0.99 | |
| 19_L | 41_L | 1.248 | 0.99 | |
| 129_Q | 203_I | 1.247 | 0.99 | |
| 120_A | 157_A | 1.247 | 0.99 | |
| 202_V | 218_M | 1.244 | 0.98 | |
| 201_A | 217_A | 1.242 | 0.98 | |
| 52_L | 61_L | 1.237 | 0.98 | |
| 106_Y | 219_M | 1.227 | 0.98 | |
| 127_K | 156_E | 1.226 | 0.98 | |
| 64_R | 70_F | 1.226 | 0.98 | |
| 149_R | 153_A | 1.226 | 0.98 | |
| 20_I | 71_I | 1.223 | 0.98 | |
| 35_R | 39_M | 1.214 | 0.98 | |
| 203_I | 207_F | 1.212 | 0.98 | |
| 11_E | 15_R | 1.197 | 0.98 | |
| 106_Y | 226_H | 1.195 | 0.98 | |
| 122_P | 209_G | 1.194 | 0.98 | |
| 125_K | 209_G | 1.189 | 0.98 | |
| 150_F | 203_I | 1.188 | 0.98 | |
| 165_Q | 169_G | 1.186 | 0.98 | |
| 202_V | 217_A | 1.184 | 0.98 | |
| 198_Q | 224_F | 1.184 | 0.98 | |
| 103_E | 160_N | 1.179 | 0.98 | |
| 147_D | 151_H | 1.177 | 0.98 | |
| 125_K | 203_I | 1.176 | 0.98 | |
| 61_L | 69_T | 1.173 | 0.98 | |
| 129_Q | 133_E | 1.173 | 0.98 | |
| 110_A | 114_W | 1.166 | 0.97 | |
| 201_A | 213_G | 1.166 | 0.97 | |
| 153_A | 157_A | 1.16 | 0.97 | |
| 15_R | 41_L | 1.16 | 0.97 | |
| 199_H | 221_H | 1.157 | 0.97 | |
| 131_C | 153_A | 1.146 | 0.97 | |
| 120_A | 124_D | 1.139 | 0.97 | |
| 56_V | 61_L | 1.132 | 0.97 | |
| 205_A | 210_D | 1.131 | 0.97 | |
| 201_A | 220_A | 1.12 | 0.96 | |
| 50_E | 53_A | 1.1 | 0.96 | |
| 67_G | 70_F | 1.096 | 0.96 | |
| 56_V | 63_S | 1.084 | 0.96 | |
| 17_R | 60_V | 1.078 | 0.95 | |
| 132_F | 200_Q | 1.062 | 0.95 | |
| 151_H | 221_H | 1.061 | 0.95 | |
| 212_D | 216_K | 1.057 | 0.95 | |
| 152_L | 156_E | 1.056 | 0.95 | |
| 162_V | 173_V | 1.055 | 0.95 | |
| 117_A | 211_A | 1.05 | 0.94 | |
| 13_A | 17_R | 1.05 | 0.94 | |
| 43_V | 48_L | 1.044 | 0.94 | |
| 96_D | 100_D | 1.036 | 0.94 | |
| 128_I | 153_A | 1.034 | 0.94 | |
| 25_L | 71_I | 1.033 | 0.94 | |
| 30_K | 70_F | 1.03 | 0.94 | |
| 117_A | 209_G | 1.025 | 0.93 | |
| 62_L | 70_F | 1.023 | 0.93 | |
| 127_K | 130_L | 1.018 | 0.93 | |
| 164_L | 168_R | 1.017 | 0.93 | |
| 145_Q | 149_R | 1.011 | 0.93 | |
| 37_L | 52_L | 1.007 | 0.93 | |
| 197_E | 201_A | 1.006 | 0.93 | |
| 134_A | 149_R | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3c7jA | 2 | 0.8411 | 100 | 0.273 | Contact Map | 0.795 |
| 2di3A | 2 | 0.9031 | 100 | 0.276 | Contact Map | 0.651 |
| 3ihuA | 2 | 0.8062 | 100 | 0.277 | Contact Map | 0.654 |
| 2hs5A | 1 | 0.8295 | 100 | 0.283 | Contact Map | 0.585 |
| 3sxyA | 2 | 0.814 | 100 | 0.284 | Contact Map | 0.779 |
| 1hw1A | 2 | 0.9109 | 100 | 0.295 | Contact Map | 0.636 |
| 4hamA | 1 | 0.4767 | 99.9 | 0.588 | Contact Map | 0.709 |
| 3by6A | 5 | 0.469 | 99.8 | 0.611 | Contact Map | 0.843 |
| 3ic7A | 2 | 0.4612 | 99.8 | 0.611 | Contact Map | 0.642 |
| 3neuA | 1 | 0.4612 | 99.8 | 0.624 | Contact Map | 0.669 |
Sequence Conservation (Image Generated using WebLogo v3)