| UniProt: | P0A8V6 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10281 | ||
| Length: | 239 (222) | ||
| Sequences: | 9717 | ||
| Seq/Len: | 43.77 |
| FADR
Paralog alert: 0.78 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: CSIR DGOR EXUR FADR GLCC LLDR MCBR NANR PDHR UXUR YDFH YIEP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 128_L | 201_S | 4.354 | 1.00 | |
| 114_R | 209_Y | 3.556 | 1.00 | |
| 204_A | 207_Q | 3.309 | 1.00 | |
| 26_P | 29_T | 3.3 | 1.00 | |
| 135_A | 194_H | 2.895 | 1.00 | |
| 19_S | 24_R | 2.741 | 1.00 | |
| 19_S | 40_L | 2.735 | 1.00 | |
| 100_N | 159_P | 2.689 | 1.00 | |
| 34_E | 45_R | 2.434 | 1.00 | |
| 107_N | 111_I | 2.394 | 1.00 | |
| 13_E | 54_R | 2.306 | 1.00 | |
| 12_A | 43_V | 2.233 | 1.00 | |
| 17_I | 58_D | 2.187 | 1.00 | |
| 12_A | 41_I | 2.155 | 1.00 | |
| 199_L | 207_Q | 2.116 | 1.00 | |
| 106_T | 217_H | 2.085 | 1.00 | |
| 120_H | 123_K | 2.031 | 1.00 | |
| 207_Q | 211_T | 1.931 | 1.00 | |
| 103_S | 115_T | 1.849 | 1.00 | |
| 63_I | 69_T | 1.831 | 1.00 | |
| 126_E | 151_G | 1.826 | 1.00 | |
| 124_A | 201_S | 1.794 | 1.00 | |
| 62_T | 72_N | 1.777 | 1.00 | |
| 123_K | 157_G | 1.762 | 1.00 | |
| 137_H | 140_A | 1.718 | 1.00 | |
| 149_F | 193_Y | 1.712 | 1.00 | |
| 151_G | 154_F | 1.674 | 1.00 | |
| 18_E | 22_N | 1.669 | 1.00 | |
| 198_A | 202_E | 1.637 | 1.00 | |
| 209_Y | 213_R | 1.63 | 1.00 | |
| 150_R | 166_N | 1.626 | 1.00 | |
| 15_Y | 19_S | 1.614 | 1.00 | |
| 114_R | 206_D | 1.602 | 1.00 | |
| 154_F | 162_G | 1.596 | 1.00 | |
| 104_V | 164_I | 1.57 | 1.00 | |
| 130_T | 144_L | 1.556 | 1.00 | |
| 131_A | 197_S | 1.549 | 1.00 | |
| 37_L | 48_L | 1.549 | 1.00 | |
| 210_E | 214_R | 1.539 | 1.00 | |
| 110_T | 209_Y | 1.53 | 1.00 | |
| 113_I | 117_F | 1.506 | 1.00 | |
| 202_E | 207_Q | 1.492 | 1.00 | |
| 100_N | 160_I | 1.466 | 1.00 | |
| 194_H | 198_A | 1.452 | 1.00 | |
| 192_F | 215_Y | 1.448 | 1.00 | |
| 64_Q | 67_K | 1.444 | 1.00 | |
| 110_T | 213_R | 1.421 | 1.00 | |
| 207_Q | 210_E | 1.42 | 1.00 | |
| 113_I | 212_V | 1.405 | 0.99 | |
| 13_E | 58_D | 1.402 | 0.99 | |
| 205_H | 209_Y | 1.395 | 0.99 | |
| 133_E | 147_N | 1.394 | 0.99 | |
| 114_R | 205_H | 1.387 | 0.99 | |
| 152_L | 200_C | 1.37 | 0.99 | |
| 111_I | 114_R | 1.364 | 0.99 | |
| 113_I | 208_V | 1.357 | 0.99 | |
| 15_Y | 18_E | 1.354 | 0.99 | |
| 106_T | 110_T | 1.352 | 0.99 | |
| 153_A | 165_L | 1.346 | 0.99 | |
| 36_E | 40_L | 1.326 | 0.99 | |
| 156_S | 162_G | 1.325 | 0.99 | |
| 6_Q | 14_E | 1.287 | 0.99 | |
| 100_N | 158_N | 1.282 | 0.99 | |
| 35_R | 39_E | 1.282 | 0.99 | |
| 124_A | 128_L | 1.278 | 0.99 | |
| 112_F | 153_A | 1.275 | 0.99 | |
| 163_L | 167_G | 1.27 | 0.99 | |
| 195_K | 211_T | 1.26 | 0.99 | |
| 129_A | 133_E | 1.259 | 0.99 | |
| 119_Q | 124_A | 1.254 | 0.99 | |
| 106_T | 213_R | 1.247 | 0.99 | |
| 147_N | 151_G | 1.231 | 0.98 | |
| 64_Q | 70_K | 1.229 | 0.98 | |
| 123_K | 155_A | 1.221 | 0.98 | |
| 15_Y | 41_I | 1.219 | 0.98 | |
| 52_L | 61_L | 1.218 | 0.98 | |
| 151_G | 155_A | 1.215 | 0.98 | |
| 145_D | 149_F | 1.215 | 0.98 | |
| 133_E | 144_L | 1.213 | 0.98 | |
| 197_S | 201_S | 1.212 | 0.98 | |
| 196_L | 211_T | 1.204 | 0.98 | |
| 105_R | 109_S | 1.197 | 0.98 | |
| 19_S | 41_I | 1.19 | 0.98 | |
| 110_T | 114_R | 1.188 | 0.98 | |
| 119_Q | 200_C | 1.185 | 0.98 | |
| 11_F | 15_Y | 1.183 | 0.98 | |
| 196_L | 212_V | 1.181 | 0.98 | |
| 56_A | 61_L | 1.168 | 0.97 | |
| 103_S | 158_N | 1.165 | 0.97 | |
| 192_F | 218_E | 1.165 | 0.97 | |
| 103_S | 118_R | 1.163 | 0.97 | |
| 126_E | 154_F | 1.162 | 0.97 | |
| 128_L | 132_N | 1.158 | 0.97 | |
| 117_F | 205_H | 1.148 | 0.97 | |
| 124_A | 203_G | 1.133 | 0.97 | |
| 195_K | 207_Q | 1.122 | 0.97 | |
| 56_A | 63_I | 1.12 | 0.96 | |
| 119_Q | 155_A | 1.117 | 0.96 | |
| 20_I | 71_V | 1.115 | 0.96 | |
| 148_I | 197_S | 1.113 | 0.96 | |
| 128_L | 197_S | 1.112 | 0.96 | |
| 199_L | 204_A | 1.105 | 0.96 | |
| 124_A | 197_S | 1.101 | 0.96 | |
| 61_L | 69_T | 1.095 | 0.96 | |
| 119_Q | 203_G | 1.091 | 0.96 | |
| 121_P | 203_G | 1.089 | 0.96 | |
| 206_D | 210_E | 1.089 | 0.96 | |
| 25_F | 71_V | 1.088 | 0.96 | |
| 130_T | 151_G | 1.085 | 0.96 | |
| 119_Q | 123_K | 1.083 | 0.96 | |
| 50_E | 53_Q | 1.083 | 0.96 | |
| 195_K | 214_R | 1.075 | 0.95 | |
| 67_K | 70_K | 1.075 | 0.95 | |
| 30_I | 70_K | 1.073 | 0.95 | |
| 150_R | 154_F | 1.073 | 0.95 | |
| 33_A | 36_E | 1.07 | 0.95 | |
| 160_I | 171_L | 1.066 | 0.95 | |
| 13_E | 17_I | 1.054 | 0.95 | |
| 94_V | 97_L | 1.046 | 0.94 | |
| 117_F | 208_V | 1.043 | 0.94 | |
| 117_F | 203_G | 1.043 | 0.94 | |
| 193_Y | 215_Y | 1.038 | 0.94 | |
| 17_I | 60_W | 1.036 | 0.94 | |
| 213_R | 217_H | 1.035 | 0.94 | |
| 131_A | 194_H | 1.018 | 0.93 | |
| 143_E | 147_N | 1.008 | 0.93 | |
| 162_G | 166_N | 1.004 | 0.93 | |
| 62_T | 70_K | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1hw1A | 2 | 0.9958 | 100 | 0.116 | Contact Map | 0.638 |
| 3c7jA | 2 | 0.887 | 100 | 0.172 | Contact Map | 0.796 |
| 3sxyA | 2 | 0.8703 | 100 | 0.174 | Contact Map | 0.791 |
| 3ihuA | 2 | 0.8619 | 100 | 0.179 | Contact Map | 0.653 |
| 2hs5A | 1 | 0.8912 | 100 | 0.18 | Contact Map | 0.569 |
| 2di3A | 2 | 0.9414 | 100 | 0.188 | Contact Map | 0.658 |
| 4hamA | 1 | 0.5063 | 99.9 | 0.53 | Contact Map | 0.694 |
| 3by6A | 5 | 0.5063 | 99.9 | 0.548 | Contact Map | 0.85 |
| 3ic7A | 2 | 0.4937 | 99.8 | 0.55 | Contact Map | 0.66 |
| 3neuA | 1 | 0.4854 | 99.8 | 0.565 | Contact Map | 0.656 |
Sequence Conservation (Image Generated using WebLogo v3)