| UniProt: | P10906 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11049 | ||
| Length: | 281 (264) | ||
| Sequences: | 22143 | ||
| Seq/Len: | 83.88 |
| UGPE
Paralog alert: 0.95 [within 20: 0.80] - ratio of genomes with paralogs Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 186_R | 190_D | 4.765 | 1.00 | |
| 34_A | 58_I | 3.873 | 1.00 | |
| 78_L | 82_V | 3.255 | 1.00 | |
| 183_S | 186_R | 2.968 | 1.00 | |
| 185_M | 189_C | 2.861 | 1.00 | |
| 178_R | 187_F | 2.766 | 1.00 | |
| 56_E | 59_H | 2.756 | 1.00 | |
| 174_V | 192_V | 2.679 | 1.00 | |
| 163_R | 167_M | 2.673 | 1.00 | |
| 56_E | 60_N | 2.607 | 1.00 | |
| 162_F | 200_L | 2.484 | 1.00 | |
| 75_R | 78_L | 2.479 | 1.00 | |
| 96_M | 188_F | 2.403 | 1.00 | |
| 104_W | 174_V | 2.373 | 1.00 | |
| 74_W | 78_L | 2.367 | 1.00 | |
| 166_F | 196_S | 2.333 | 1.00 | |
| 184_P | 187_F | 2.274 | 1.00 | |
| 76_M | 233_G | 2.215 | 1.00 | |
| 59_H | 63_V | 2.18 | 1.00 | |
| 88_T | 204_F | 2.086 | 1.00 | |
| 31_F | 255_L | 2.081 | 1.00 | |
| 182_A | 186_R | 2.067 | 1.00 | |
| 177_A | 187_F | 2.038 | 1.00 | |
| 158_A | 203_L | 1.992 | 1.00 | |
| 103_V | 167_M | 1.981 | 1.00 | |
| 186_R | 189_C | 1.937 | 1.00 | |
| 96_M | 196_S | 1.877 | 1.00 | |
| 75_R | 79_N | 1.868 | 1.00 | |
| 84_A | 208_F | 1.864 | 1.00 | |
| 90_G | 153_M | 1.856 | 1.00 | |
| 178_R | 184_P | 1.853 | 1.00 | |
| 95_S | 158_A | 1.83 | 1.00 | |
| 107_F | 110_R | 1.805 | 1.00 | |
| 32_V | 36_L | 1.796 | 1.00 | |
| 177_A | 182_A | 1.787 | 1.00 | |
| 173_L | 195_L | 1.782 | 1.00 | |
| 92_I | 204_F | 1.759 | 1.00 | |
| 60_N | 249_S | 1.756 | 1.00 | |
| 246_E | 249_S | 1.75 | 1.00 | |
| 28_Y | 32_V | 1.749 | 1.00 | |
| 174_V | 187_F | 1.739 | 1.00 | |
| 96_M | 162_F | 1.734 | 1.00 | |
| 165_F | 199_N | 1.723 | 1.00 | |
| 58_I | 255_L | 1.693 | 1.00 | |
| 193_F | 200_L | 1.667 | 1.00 | |
| 82_V | 86_S | 1.636 | 1.00 | |
| 202_A | 206_I | 1.587 | 1.00 | |
| 106_R | 110_R | 1.574 | 1.00 | |
| 54_L | 57_N | 1.568 | 1.00 | |
| 57_N | 248_N | 1.542 | 1.00 | |
| 87_I | 211_G | 1.539 | 1.00 | |
| 55_L | 59_H | 1.537 | 1.00 | |
| 103_V | 163_R | 1.51 | 1.00 | |
| 86_S | 149_T | 1.5 | 1.00 | |
| 98_S | 159_T | 1.499 | 1.00 | |
| 104_W | 171_D | 1.492 | 1.00 | |
| 99_A | 162_F | 1.487 | 1.00 | |
| 174_V | 178_R | 1.479 | 1.00 | |
| 215_Y | 219_L | 1.469 | 1.00 | |
| 25_F | 29_V | 1.466 | 1.00 | |
| 158_A | 207_T | 1.441 | 1.00 | |
| 230_T | 238_I | 1.439 | 1.00 | |
| 102_I | 159_T | 1.432 | 1.00 | |
| 183_S | 187_F | 1.429 | 1.00 | |
| 162_F | 203_L | 1.422 | 1.00 | |
| 177_A | 191_I | 1.41 | 1.00 | |
| 109_L | 112_L | 1.407 | 0.99 | |
| 171_D | 174_V | 1.341 | 0.99 | |
| 93_T | 97_L | 1.339 | 0.99 | |
| 169_L | 195_L | 1.325 | 0.99 | |
| 81_F | 85_F | 1.318 | 0.99 | |
| 80_S | 231_V | 1.318 | 0.99 | |
| 35_T | 53_H | 1.311 | 0.99 | |
| 166_F | 192_V | 1.298 | 0.99 | |
| 61_I | 256_L | 1.291 | 0.99 | |
| 29_V | 33_A | 1.276 | 0.99 | |
| 58_I | 252_V | 1.273 | 0.99 | |
| 143_D | 224_D | 1.273 | 0.99 | |
| 96_M | 200_L | 1.272 | 0.99 | |
| 188_F | 193_F | 1.271 | 0.99 | |
| 33_A | 251_M | 1.27 | 0.99 | |
| 165_F | 196_S | 1.266 | 0.99 | |
| 217_W | 221_I | 1.265 | 0.99 | |
| 233_G | 237_M | 1.26 | 0.99 | |
| 182_A | 187_F | 1.258 | 0.99 | |
| 228_G | 236_G | 1.255 | 0.99 | |
| 195_L | 198_T | 1.249 | 0.99 | |
| 91_K | 95_S | 1.246 | 0.98 | |
| 91_K | 207_T | 1.245 | 0.98 | |
| 60_N | 63_V | 1.237 | 0.98 | |
| 229_T | 232_A | 1.217 | 0.98 | |
| 30_A | 255_L | 1.217 | 0.98 | |
| 172_E | 175_E | 1.212 | 0.98 | |
| 112_L | 116_M | 1.201 | 0.98 | |
| 86_S | 89_L | 1.196 | 0.98 | |
| 162_F | 199_N | 1.182 | 0.98 | |
| 85_F | 89_L | 1.182 | 0.98 | |
| 79_N | 82_V | 1.18 | 0.98 | |
| 100_F | 166_F | 1.175 | 0.98 | |
| 129_I | 220_L | 1.172 | 0.98 | |
| 86_S | 90_G | 1.169 | 0.97 | |
| 60_N | 246_E | 1.162 | 0.97 | |
| 169_L | 196_S | 1.155 | 0.97 | |
| 145_Y | 227_L | 1.148 | 0.97 | |
| 174_V | 184_P | 1.125 | 0.97 | |
| 215_Y | 235_K | 1.1 | 0.96 | |
| 83_M | 229_T | 1.095 | 0.96 | |
| 114_F | 163_R | 1.091 | 0.96 | |
| 78_L | 81_F | 1.088 | 0.96 | |
| 62_W | 74_W | 1.087 | 0.96 | |
| 82_V | 145_Y | 1.085 | 0.96 | |
| 97_L | 101_A | 1.076 | 0.95 | |
| 82_V | 85_F | 1.071 | 0.95 | |
| 89_L | 93_T | 1.063 | 0.95 | |
| 100_F | 188_F | 1.063 | 0.95 | |
| 13_H | 17_I | 1.055 | 0.95 | |
| 17_I | 21_A | 1.048 | 0.94 | |
| 197_K | 200_L | 1.047 | 0.94 | |
| 84_A | 88_T | 1.04 | 0.94 | |
| 30_A | 251_M | 1.038 | 0.94 | |
| 214_Q | 218_P | 1.033 | 0.94 | |
| 29_V | 32_V | 1.03 | 0.94 | |
| 112_L | 115_W | 1.03 | 0.94 | |
| 224_D | 227_L | 1.028 | 0.94 | |
| 87_I | 91_K | 1.026 | 0.94 | |
| 230_T | 234_I | 1.025 | 0.93 | |
| 132_T | 135_V | 1.025 | 0.93 | |
| 35_T | 54_L | 1.024 | 0.93 | |
| 161_L | 203_L | 1.015 | 0.93 | |
| 158_A | 162_F | 1.015 | 0.93 | |
| 197_K | 271_A | 1.015 | 0.93 | |
| 92_I | 200_L | 1.013 | 0.93 | |
| 110_R | 167_M | 1.007 | 0.93 | |
| 189_C | 193_F | 1.002 | 0.92 | |
| 188_F | 192_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3rlfG | 1 | 0.9822 | 100 | 0.299 | Contact Map | 0.759 |
| 2onkC | 4 | 0.8861 | 100 | 0.37 | Contact Map | 0.732 |
| 3d31C | 2 | 0.8968 | 100 | 0.387 | Contact Map | 0.663 |
| 3rlfF | 1 | 0.9644 | 100 | 0.416 | Contact Map | 0.612 |
| 3tuiA | 4 | 0.7367 | 99.9 | 0.569 | Contact Map | 0.745 |
| 2k1eA | 4 | 0.3594 | 1.6 | 0.967 | Contact Map | 0.422 |
| 2jwaA | 2 | 0.1566 | 1.5 | 0.968 | Contact Map | 0.521 |
| 3buaE | 4 | 0.1281 | 1.4 | 0.968 | Contact Map | |
| 1iq5B | 1 | 0.0427 | 1.3 | 0.969 | Contact Map | |
| 3ne5A | 1 | 0.3096 | 1.3 | 0.969 | Contact Map | 0.546 |
Sequence Conservation (Image Generated using WebLogo v3)