| UniProt: | P0AFL1 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11632 | ||
| Length: | 281 (248) | ||
| Sequences: | 22747 | ||
| Seq/Len: | 91.72 |
| POTI
Paralog alert: 0.95 [within 20: 0.83] - ratio of genomes with paralogs Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 183_K | 187_V | 4.309 | 1.00 | |
| 34_S | 52_Y | 3.75 | 1.00 | |
| 66_G | 70_T | 3.205 | 1.00 | |
| 180_T | 183_K | 2.761 | 1.00 | |
| 182_L | 186_F | 2.696 | 1.00 | |
| 50_R | 53_G | 2.572 | 1.00 | |
| 175_M | 184_V | 2.553 | 1.00 | |
| 160_S | 164_R | 2.498 | 1.00 | |
| 50_R | 54_E | 2.463 | 1.00 | |
| 64_A | 229_L | 2.418 | 1.00 | |
| 171_E | 189_T | 2.404 | 1.00 | |
| 62_M | 66_G | 2.288 | 1.00 | |
| 159_I | 197_I | 2.273 | 1.00 | |
| 78_A | 148_V | 2.27 | 1.00 | |
| 63_S | 66_G | 2.264 | 1.00 | |
| 181_P | 184_V | 2.229 | 1.00 | |
| 92_R | 171_E | 2.221 | 1.00 | |
| 174_A | 184_V | 2.215 | 1.00 | |
| 163_L | 193_I | 2.187 | 1.00 | |
| 53_G | 57_R | 2.181 | 1.00 | |
| 84_T | 185_F | 2.137 | 1.00 | |
| 74_C | 144_W | 2.095 | 1.00 | |
| 76_A | 201_W | 2.048 | 1.00 | |
| 224_T | 232_S | 2.022 | 1.00 | |
| 179_A | 183_K | 1.962 | 1.00 | |
| 155_V | 200_G | 1.941 | 1.00 | |
| 31_V | 247_T | 1.924 | 1.00 | |
| 183_K | 186_F | 1.906 | 1.00 | |
| 91_V | 164_R | 1.899 | 1.00 | |
| 162_R | 196_A | 1.883 | 1.00 | |
| 170_I | 192_M | 1.767 | 1.00 | |
| 96_F | 99_S | 1.756 | 1.00 | |
| 72_A | 205_F | 1.713 | 1.00 | |
| 83_G | 155_V | 1.711 | 1.00 | |
| 174_A | 179_A | 1.706 | 1.00 | |
| 175_M | 181_P | 1.705 | 1.00 | |
| 84_T | 193_I | 1.694 | 1.00 | |
| 80_A | 201_W | 1.693 | 1.00 | |
| 32_I | 36_N | 1.684 | 1.00 | |
| 63_S | 67_L | 1.667 | 1.00 | |
| 84_T | 159_I | 1.665 | 1.00 | |
| 171_E | 184_V | 1.65 | 1.00 | |
| 28_L | 32_I | 1.641 | 1.00 | |
| 238_V | 241_E | 1.638 | 1.00 | |
| 54_E | 241_E | 1.612 | 1.00 | |
| 70_T | 74_C | 1.61 | 1.00 | |
| 70_T | 140_M | 1.595 | 1.00 | |
| 52_Y | 247_T | 1.585 | 1.00 | |
| 190_L | 197_I | 1.584 | 1.00 | |
| 212_L | 231_F | 1.531 | 1.00 | |
| 91_V | 160_S | 1.461 | 1.00 | |
| 95_R | 99_S | 1.46 | 1.00 | |
| 75_A | 208_S | 1.459 | 1.00 | |
| 139_G | 223_A | 1.437 | 1.00 | |
| 125_F | 142_T | 1.436 | 1.00 | |
| 155_V | 204_A | 1.431 | 1.00 | |
| 171_E | 175_M | 1.426 | 1.00 | |
| 48_S | 51_W | 1.425 | 1.00 | |
| 87_A | 159_I | 1.42 | 1.00 | |
| 86_A | 156_A | 1.411 | 1.00 | |
| 174_A | 188_I | 1.406 | 0.99 | |
| 92_R | 168_R | 1.381 | 0.99 | |
| 49_T | 53_G | 1.381 | 0.99 | |
| 159_I | 200_G | 1.376 | 0.99 | |
| 199_S | 203_L | 1.376 | 0.99 | |
| 180_T | 184_V | 1.367 | 0.99 | |
| 25_A | 29_M | 1.344 | 0.99 | |
| 168_R | 171_E | 1.337 | 0.99 | |
| 98_G | 101_G | 1.331 | 0.99 | |
| 140_M | 223_A | 1.327 | 0.99 | |
| 90_L | 156_A | 1.324 | 0.99 | |
| 81_I | 85_I | 1.306 | 0.99 | |
| 51_W | 240_P | 1.305 | 0.99 | |
| 212_L | 216_S | 1.296 | 0.99 | |
| 163_L | 189_T | 1.29 | 0.99 | |
| 71_I | 225_T | 1.284 | 0.99 | |
| 166_L | 192_M | 1.256 | 0.99 | |
| 192_M | 195_P | 1.251 | 0.99 | |
| 84_T | 197_I | 1.224 | 0.98 | |
| 29_M | 33_Y | 1.224 | 0.98 | |
| 69_L | 73_A | 1.221 | 0.98 | |
| 225_T | 228_M | 1.219 | 0.98 | |
| 54_E | 57_R | 1.21 | 0.98 | |
| 169_S | 172_E | 1.196 | 0.98 | |
| 141_L | 145_L | 1.194 | 0.98 | |
| 65_V | 226_L | 1.189 | 0.98 | |
| 146_A | 218_V | 1.186 | 0.98 | |
| 68_S | 227_P | 1.179 | 0.98 | |
| 162_R | 193_I | 1.169 | 0.97 | |
| 55_L | 248_L | 1.163 | 0.97 | |
| 52_Y | 244_A | 1.161 | 0.97 | |
| 73_A | 77_T | 1.157 | 0.97 | |
| 229_L | 233_S | 1.154 | 0.97 | |
| 74_C | 77_T | 1.145 | 0.97 | |
| 30_L | 247_T | 1.135 | 0.97 | |
| 147_H | 208_S | 1.126 | 0.97 | |
| 75_A | 147_H | 1.123 | 0.97 | |
| 33_Y | 243_N | 1.123 | 0.97 | |
| 103_A | 160_S | 1.12 | 0.96 | |
| 179_A | 184_V | 1.115 | 0.96 | |
| 74_C | 78_A | 1.107 | 0.96 | |
| 54_E | 238_V | 1.104 | 0.96 | |
| 152_T | 156_A | 1.101 | 0.96 | |
| 79_A | 83_G | 1.1 | 0.96 | |
| 79_A | 204_A | 1.093 | 0.96 | |
| 101_G | 105_M | 1.083 | 0.96 | |
| 185_F | 190_L | 1.081 | 0.95 | |
| 194_M | 197_I | 1.081 | 0.95 | |
| 67_L | 70_T | 1.079 | 0.95 | |
| 35_F | 47_W | 1.063 | 0.95 | |
| 171_E | 181_P | 1.056 | 0.95 | |
| 88_V | 163_L | 1.053 | 0.95 | |
| 233_S | 245_L | 1.047 | 0.94 | |
| 233_S | 238_V | 1.046 | 0.94 | |
| 101_G | 104_F | 1.038 | 0.94 | |
| 155_V | 159_I | 1.028 | 0.94 | |
| 68_S | 226_L | 1.022 | 0.93 | |
| 233_S | 236_M | 1.021 | 0.93 | |
| 78_A | 144_W | 1.02 | 0.93 | |
| 56_L | 62_M | 1.014 | 0.93 | |
| 159_I | 196_A | 1.011 | 0.93 | |
| 66_G | 69_L | 1.008 | 0.93 | |
| 85_I | 89_V | 1.008 | 0.93 | |
| 80_A | 197_I | 1.006 | 0.93 | |
| 166_L | 193_I | 1.004 | 0.93 | |
| 77_T | 81_I | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2onkC | 4 | 0.9288 | 100 | 0.386 | Contact Map | 0.754 |
| 3d31C | 2 | 0.9288 | 100 | 0.407 | Contact Map | 0.667 |
| 3rlfG | 1 | 0.9715 | 100 | 0.412 | Contact Map | 0.771 |
| 3rlfF | 1 | 0.9537 | 100 | 0.444 | Contact Map | 0.642 |
| 3tuiA | 4 | 0.7438 | 99.9 | 0.579 | Contact Map | 0.758 |
| 2l53B | 1 | 0.0641 | 4.4 | 0.962 | Contact Map | |
| 2kxwB | 1 | 0.0641 | 3.7 | 0.963 | Contact Map | |
| 3hd7A | 2 | 0.1174 | 3.3 | 0.964 | Contact Map | |
| 3qf4B | 1 | 0.3879 | 1.9 | 0.969 | Contact Map | 0.446 |
| 4gn0A | 4 | 0.2135 | 1.9 | 0.969 | Contact Map | 0.464 |
Sequence Conservation (Image Generated using WebLogo v3)