| UniProt: | P0AF01 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10002 | ||
| Length: | 229 (220) | ||
| Sequences: | 24543 | ||
| Seq/Len: | 111.56 |
| MODB
Paralog alert: 0.93 [within 20: 0.81] - ratio of genomes with paralogs Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 135_R | 139_T | 4.234 | 1.00 | |
| 12_L | 16_K | 3.339 | 1.00 | |
| 132_G | 135_R | 2.68 | 1.00 | |
| 134_W | 138_F | 2.656 | 1.00 | |
| 112_R | 116_E | 2.591 | 1.00 | |
| 127_R | 136_V | 2.577 | 1.00 | |
| 123_E | 141_T | 2.575 | 1.00 | |
| 10_A | 184_A | 2.402 | 1.00 | |
| 126_A | 136_V | 2.293 | 1.00 | |
| 38_R | 123_E | 2.287 | 1.00 | |
| 133_R | 136_V | 2.279 | 1.00 | |
| 24_F | 100_A | 2.267 | 1.00 | |
| 9_Q | 12_L | 2.226 | 1.00 | |
| 111_I | 149_I | 2.204 | 1.00 | |
| 115_L | 145_T | 2.133 | 1.00 | |
| 20_L | 96_V | 2.129 | 1.00 | |
| 179_R | 187_T | 2.116 | 1.00 | |
| 8_W | 12_L | 2.109 | 1.00 | |
| 22_V | 153_T | 2.086 | 1.00 | |
| 131_A | 135_R | 2.068 | 1.00 | |
| 30_I | 137_F | 2.044 | 1.00 | |
| 114_A | 148_G | 2.03 | 1.00 | |
| 107_M | 152_G | 1.977 | 1.00 | |
| 127_R | 133_R | 1.914 | 1.00 | |
| 37_V | 116_E | 1.912 | 1.00 | |
| 135_R | 138_F | 1.87 | 1.00 | |
| 194_G | 197_G | 1.83 | 1.00 | |
| 18_S | 157_F | 1.77 | 1.00 | |
| 16_K | 92_W | 1.765 | 1.00 | |
| 26_L | 153_T | 1.747 | 1.00 | |
| 30_I | 145_T | 1.745 | 1.00 | |
| 41_F | 44_K | 1.731 | 1.00 | |
| 122_L | 144_L | 1.707 | 1.00 | |
| 126_A | 131_A | 1.695 | 1.00 | |
| 123_E | 136_V | 1.666 | 1.00 | |
| 80_L | 86_I | 1.638 | 1.00 | |
| 91_S | 178_T | 1.614 | 1.00 | |
| 30_I | 111_I | 1.581 | 1.00 | |
| 29_G | 107_M | 1.578 | 1.00 | |
| 16_K | 20_L | 1.57 | 1.00 | |
| 40_T | 44_K | 1.527 | 1.00 | |
| 123_E | 127_R | 1.521 | 1.00 | |
| 164_F | 186_Y | 1.509 | 1.00 | |
| 9_Q | 13_L | 1.496 | 1.00 | |
| 142_L | 149_I | 1.496 | 1.00 | |
| 27_P | 31_F | 1.485 | 1.00 | |
| 33_A | 111_I | 1.477 | 1.00 | |
| 132_G | 136_V | 1.443 | 1.00 | |
| 21_A | 160_S | 1.435 | 1.00 | |
| 37_V | 112_R | 1.413 | 1.00 | |
| 69_S | 76_I | 1.408 | 1.00 | |
| 32_F | 108_V | 1.397 | 0.99 | |
| 38_R | 120_V | 1.388 | 0.99 | |
| 107_M | 156_A | 1.384 | 0.99 | |
| 36_L | 108_V | 1.371 | 0.99 | |
| 171_V | 174_I | 1.334 | 0.99 | |
| 111_I | 152_G | 1.331 | 0.99 | |
| 151_V | 155_L | 1.331 | 0.99 | |
| 173_N | 177_E | 1.329 | 0.99 | |
| 43_G | 46_L | 1.328 | 0.99 | |
| 126_A | 140_I | 1.324 | 0.99 | |
| 164_F | 168_I | 1.318 | 0.99 | |
| 115_L | 141_T | 1.313 | 0.99 | |
| 120_V | 123_E | 1.294 | 0.99 | |
| 11_V | 181_I | 1.293 | 0.99 | |
| 48_D | 112_R | 1.289 | 0.99 | |
| 93_R | 97_L | 1.275 | 0.99 | |
| 70_M | 94_G | 1.264 | 0.99 | |
| 214_L | 218_W | 1.263 | 0.99 | |
| 92_W | 178_T | 1.245 | 0.98 | |
| 17_V | 180_T | 1.243 | 0.98 | |
| 78_E | 82_D | 1.242 | 0.98 | |
| 118_V | 144_L | 1.236 | 0.98 | |
| 104_F | 108_V | 1.216 | 0.98 | |
| 98_A | 170_F | 1.201 | 0.98 | |
| 13_L | 16_K | 1.199 | 0.98 | |
| 121_K | 124_Q | 1.193 | 0.98 | |
| 30_I | 149_I | 1.19 | 0.98 | |
| 77_G | 80_L | 1.187 | 0.98 | |
| 180_T | 183_S | 1.159 | 0.97 | |
| 20_L | 24_F | 1.155 | 0.97 | |
| 24_F | 96_V | 1.15 | 0.97 | |
| 25_S | 156_A | 1.146 | 0.97 | |
| 144_L | 147_P | 1.136 | 0.97 | |
| 79_R | 84_F | 1.136 | 0.97 | |
| 184_A | 188_L | 1.135 | 0.97 | |
| 92_W | 96_V | 1.133 | 0.97 | |
| 15_L | 19_S | 1.119 | 0.96 | |
| 79_R | 82_D | 1.114 | 0.96 | |
| 167_T | 180_T | 1.11 | 0.96 | |
| 34_W | 115_L | 1.109 | 0.96 | |
| 19_S | 23_L | 1.106 | 0.96 | |
| 23_L | 27_P | 1.103 | 0.96 | |
| 137_F | 142_L | 1.101 | 0.96 | |
| 131_A | 136_V | 1.1 | 0.96 | |
| 166_A | 170_F | 1.1 | 0.96 | |
| 20_L | 23_L | 1.097 | 0.96 | |
| 31_F | 35_L | 1.087 | 0.96 | |
| 184_A | 201_L | 1.075 | 0.95 | |
| 46_L | 50_V | 1.068 | 0.95 | |
| 188_L | 194_G | 1.059 | 0.95 | |
| 16_K | 19_S | 1.042 | 0.94 | |
| 21_A | 99_A | 1.04 | 0.94 | |
| 37_V | 115_L | 1.033 | 0.94 | |
| 138_F | 142_L | 1.027 | 0.94 | |
| 46_L | 49_S | 1.025 | 0.93 | |
| 25_S | 29_G | 1.022 | 0.93 | |
| 99_A | 160_S | 1.022 | 0.93 | |
| 14_S | 181_I | 1.021 | 0.93 | |
| 146_L | 149_I | 1.021 | 0.93 | |
| 120_V | 124_Q | 1.02 | 0.93 | |
| 14_S | 182_P | 1.02 | 0.93 | |
| 114_A | 145_T | 1.017 | 0.93 | |
| 78_E | 81_Y | 1.014 | 0.93 | |
| 12_L | 15_L | 1.006 | 0.93 | |
| 188_L | 192_P | 1.004 | 0.93 | |
| 111_I | 148_G | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2onkC | 4 | 0.9607 | 100 | 0.281 | Contact Map | 0.76 |
| 3d31C | 2 | 0.9694 | 100 | 0.282 | Contact Map | 0.696 |
| 3rlfF | 1 | 0.9825 | 100 | 0.312 | Contact Map | 0.704 |
| 3rlfG | 1 | 0.9563 | 100 | 0.383 | Contact Map | 0.785 |
| 3tuiA | 4 | 0.8996 | 99.9 | 0.453 | Contact Map | 0.766 |
| 2m20A | 2 | 0.1659 | 3.7 | 0.954 | Contact Map | 0.211 |
| 2yl4A | 1 | 0.4105 | 1.8 | 0.961 | Contact Map | 0.269 |
| 2kluA | 1 | 0.1703 | 1.5 | 0.963 | Contact Map | 0 |
| 3qf4B | 1 | 0.4716 | 1.2 | 0.965 | Contact Map | 0.406 |
| 2vqeH | 1 | 0.2009 | 1.2 | 0.965 | Contact Map | 0.25 |
Sequence Conservation (Image Generated using WebLogo v3)