| UniProt: | P0AFR9 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13765 | ||
| Length: | 264 (245) | ||
| Sequences: | 24571 | ||
| Seq/Len: | 100.29 |
| YDCV
Paralog alert: 0.96 [within 20: 0.88] - ratio of genomes with paralogs Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 176_Q | 180_Y | 4.352 | 1.00 | |
| 32_A | 52_F | 3.381 | 1.00 | |
| 66_T | 70_K | 3.276 | 1.00 | |
| 173_N | 176_Q | 2.733 | 1.00 | |
| 175_W | 179_R | 2.699 | 1.00 | |
| 50_R | 53_S | 2.581 | 1.00 | |
| 168_M | 177_T | 2.547 | 1.00 | |
| 164_V | 182_V | 2.503 | 1.00 | |
| 153_I | 157_R | 2.487 | 1.00 | |
| 50_R | 54_V | 2.425 | 1.00 | |
| 64_A | 221_W | 2.367 | 1.00 | |
| 63_D | 66_T | 2.339 | 1.00 | |
| 78_I | 141_A | 2.333 | 1.00 | |
| 62_L | 66_T | 2.27 | 1.00 | |
| 92_R | 164_V | 2.231 | 1.00 | |
| 152_V | 190_L | 2.231 | 1.00 | |
| 167_S | 177_T | 2.22 | 1.00 | |
| 174_G | 177_T | 2.212 | 1.00 | |
| 84_T | 178_F | 2.18 | 1.00 | |
| 53_S | 57_Q | 2.168 | 1.00 | |
| 76_T | 194_G | 2.164 | 1.00 | |
| 156_F | 186_L | 2.137 | 1.00 | |
| 74_L | 137_V | 2.096 | 1.00 | |
| 216_R | 224_N | 2.048 | 1.00 | |
| 172_A | 176_Q | 2.03 | 1.00 | |
| 155_R | 189_A | 1.997 | 1.00 | |
| 148_V | 193_G | 1.933 | 1.00 | |
| 176_Q | 179_R | 1.93 | 1.00 | |
| 29_A | 240_L | 1.859 | 1.00 | |
| 91_W | 157_R | 1.839 | 1.00 | |
| 72_A | 198_F | 1.806 | 1.00 | |
| 168_M | 174_G | 1.785 | 1.00 | |
| 95_F | 98_K | 1.775 | 1.00 | |
| 231_D | 234_V | 1.775 | 1.00 | |
| 163_L | 185_N | 1.77 | 1.00 | |
| 84_T | 186_L | 1.734 | 1.00 | |
| 167_S | 172_A | 1.706 | 1.00 | |
| 26_L | 30_A | 1.686 | 1.00 | |
| 70_K | 133_F | 1.685 | 1.00 | |
| 63_D | 67_L | 1.681 | 1.00 | |
| 80_L | 194_G | 1.677 | 1.00 | |
| 83_G | 148_V | 1.657 | 1.00 | |
| 164_V | 177_T | 1.655 | 1.00 | |
| 70_K | 74_L | 1.605 | 1.00 | |
| 30_A | 34_N | 1.598 | 1.00 | |
| 84_T | 152_V | 1.587 | 1.00 | |
| 52_F | 240_L | 1.579 | 1.00 | |
| 54_V | 234_V | 1.545 | 1.00 | |
| 183_L | 190_L | 1.538 | 1.00 | |
| 205_I | 223_L | 1.51 | 1.00 | |
| 94_D | 98_K | 1.503 | 1.00 | |
| 75_A | 201_S | 1.495 | 1.00 | |
| 164_V | 168_M | 1.472 | 1.00 | |
| 49_L | 53_S | 1.462 | 1.00 | |
| 48_T | 51_W | 1.425 | 1.00 | |
| 173_N | 177_T | 1.419 | 1.00 | |
| 92_R | 161_W | 1.399 | 0.99 | |
| 91_W | 153_I | 1.397 | 0.99 | |
| 87_A | 152_V | 1.382 | 0.99 | |
| 192_A | 196_L | 1.377 | 0.99 | |
| 167_S | 181_V | 1.377 | 0.99 | |
| 81_V | 85_L | 1.374 | 0.99 | |
| 124_F | 135_T | 1.366 | 0.99 | |
| 86_A | 149_F | 1.364 | 0.99 | |
| 23_F | 27_I | 1.351 | 0.99 | |
| 148_V | 197_A | 1.35 | 0.99 | |
| 97_G | 100_A | 1.349 | 0.99 | |
| 161_W | 164_V | 1.326 | 0.99 | |
| 152_V | 193_G | 1.305 | 0.99 | |
| 51_W | 233_P | 1.287 | 0.99 | |
| 156_F | 182_V | 1.28 | 0.99 | |
| 90_L | 149_F | 1.279 | 0.99 | |
| 134_F | 138_V | 1.265 | 0.99 | |
| 65_V | 218_L | 1.263 | 0.99 | |
| 159_T | 185_N | 1.245 | 0.98 | |
| 205_I | 209_T | 1.233 | 0.98 | |
| 71_V | 217_T | 1.222 | 0.98 | |
| 162_S | 165_E | 1.215 | 0.98 | |
| 54_V | 57_Q | 1.206 | 0.98 | |
| 27_I | 31_Y | 1.201 | 0.98 | |
| 84_T | 190_L | 1.199 | 0.98 | |
| 217_T | 220_L | 1.182 | 0.98 | |
| 67_L | 70_K | 1.175 | 0.98 | |
| 69_L | 73_A | 1.174 | 0.98 | |
| 139_G | 211_T | 1.172 | 0.98 | |
| 185_N | 188_S | 1.152 | 0.97 | |
| 178_F | 183_L | 1.151 | 0.97 | |
| 74_L | 78_I | 1.146 | 0.97 | |
| 73_A | 77_L | 1.145 | 0.97 | |
| 102_S | 153_I | 1.141 | 0.97 | |
| 55_A | 241_L | 1.141 | 0.97 | |
| 79_A | 197_A | 1.135 | 0.97 | |
| 33_F | 47_L | 1.134 | 0.97 | |
| 221_W | 225_Q | 1.125 | 0.97 | |
| 251_L | 255_W | 1.116 | 0.96 | |
| 35_T | 38_A | 1.115 | 0.96 | |
| 88_A | 156_F | 1.114 | 0.96 | |
| 145_V | 149_F | 1.1 | 0.96 | |
| 52_F | 237_V | 1.096 | 0.96 | |
| 31_Y | 236_N | 1.095 | 0.96 | |
| 172_A | 177_T | 1.093 | 0.96 | |
| 85_L | 89_A | 1.092 | 0.96 | |
| 74_L | 77_L | 1.086 | 0.96 | |
| 221_W | 238_V | 1.083 | 0.96 | |
| 155_R | 186_L | 1.077 | 0.95 | |
| 208_T | 217_T | 1.074 | 0.95 | |
| 75_A | 140_H | 1.071 | 0.95 | |
| 78_I | 137_V | 1.07 | 0.95 | |
| 79_A | 83_G | 1.068 | 0.95 | |
| 187_S | 190_L | 1.068 | 0.95 | |
| 225_Q | 231_D | 1.063 | 0.95 | |
| 100_A | 104_L | 1.062 | 0.95 | |
| 68_S | 219_P | 1.05 | 0.94 | |
| 28_I | 240_L | 1.047 | 0.94 | |
| 133_F | 137_V | 1.042 | 0.94 | |
| 100_A | 103_L | 1.037 | 0.94 | |
| 152_V | 189_A | 1.035 | 0.94 | |
| 164_V | 174_G | 1.035 | 0.94 | |
| 77_L | 81_V | 1.031 | 0.94 | |
| 60_D | 63_D | 1.024 | 0.93 | |
| 88_A | 178_F | 1.021 | 0.93 | |
| 70_K | 73_A | 1.021 | 0.93 | |
| 140_H | 201_S | 1.02 | 0.93 | |
| 54_V | 231_D | 1.018 | 0.93 | |
| 68_S | 218_L | 1.017 | 0.93 | |
| 136_I | 208_T | 1 | 0.92 | |
| 66_T | 69_L | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2onkC | 4 | 0.947 | 100 | 0.331 | Contact Map | 0.756 |
| 3d31C | 2 | 0.9508 | 100 | 0.348 | Contact Map | 0.681 |
| 3rlfG | 1 | 0.9924 | 100 | 0.357 | Contact Map | 0.761 |
| 3rlfF | 1 | 0.9924 | 100 | 0.382 | Contact Map | 0.646 |
| 3tuiA | 4 | 0.7879 | 99.9 | 0.533 | Contact Map | 0.768 |
| 1jb0K | 1 | 0.1553 | 2.4 | 0.964 | Contact Map | 0 |
| 1iijA | 1 | 0.1326 | 1.7 | 0.966 | Contact Map | 0.662 |
| 2jdjA | 2 | 0.1326 | 1.7 | 0.966 | Contact Map | 0.15 |
| 4b19A | 1 | 0.1136 | 1.5 | 0.967 | Contact Map | 0.459 |
| 2m20A | 2 | 0.1326 | 1.3 | 0.968 | Contact Map | 0.124 |
Sequence Conservation (Image Generated using WebLogo v3)