| UniProt: | P07654 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10782 | ||
| Length: | 296 (256) | ||
| Sequences: | 22442 | ||
| Seq/Len: | 87.66 |
| PSTA
Paralog alert: 0.97 [within 20: 0.79] - ratio of genomes with paralogs Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 196_K | 200_A | 4.352 | 1.00 | |
| 52_T | 70_P | 3.303 | 1.00 | |
| 84_A | 88_L | 2.998 | 1.00 | |
| 193_P | 196_K | 2.866 | 1.00 | |
| 195_W | 199_S | 2.715 | 1.00 | |
| 173_E | 177_K | 2.576 | 1.00 | |
| 92_W | 157_V | 2.567 | 1.00 | |
| 188_Y | 197_M | 2.539 | 1.00 | |
| 110_E | 184_R | 2.494 | 1.00 | |
| 68_M | 71_P | 2.448 | 1.00 | |
| 102_I | 198_I | 2.377 | 1.00 | |
| 187_A | 197_M | 2.374 | 1.00 | |
| 82_A | 252_T | 2.345 | 1.00 | |
| 184_R | 202_T | 2.33 | 1.00 | |
| 172_T | 210_I | 2.329 | 1.00 | |
| 96_F | 161_A | 2.304 | 1.00 | |
| 80_A | 84_A | 2.269 | 1.00 | |
| 68_M | 72_P | 2.263 | 1.00 | |
| 81_N | 84_A | 2.25 | 1.00 | |
| 194_K | 197_M | 2.117 | 1.00 | |
| 176_L | 206_S | 2.079 | 1.00 | |
| 247_A | 255_K | 2.03 | 1.00 | |
| 109_A | 177_K | 1.922 | 1.00 | |
| 192_T | 196_K | 1.894 | 1.00 | |
| 90_I | 218_I | 1.893 | 1.00 | |
| 71_P | 75_E | 1.87 | 1.00 | |
| 98_T | 214_I | 1.868 | 1.00 | |
| 196_K | 199_S | 1.83 | 1.00 | |
| 175_M | 209_G | 1.812 | 1.00 | |
| 101_G | 168_V | 1.793 | 1.00 | |
| 50_M | 54_T | 1.774 | 1.00 | |
| 49_L | 273_L | 1.766 | 1.00 | |
| 94_T | 214_I | 1.766 | 1.00 | |
| 46_I | 50_M | 1.748 | 1.00 | |
| 115_S | 118_A | 1.741 | 1.00 | |
| 188_Y | 194_K | 1.74 | 1.00 | |
| 152_S | 246_I | 1.729 | 1.00 | |
| 81_N | 85_G | 1.728 | 1.00 | |
| 168_V | 213_G | 1.694 | 1.00 | |
| 102_I | 172_T | 1.674 | 1.00 | |
| 187_A | 192_T | 1.65 | 1.00 | |
| 183_L | 205_A | 1.595 | 1.00 | |
| 105_G | 172_T | 1.579 | 1.00 | |
| 88_L | 153_G | 1.577 | 1.00 | |
| 225_T | 254_F | 1.563 | 1.00 | |
| 203_L | 210_I | 1.56 | 1.00 | |
| 184_R | 197_M | 1.557 | 1.00 | |
| 109_A | 173_E | 1.529 | 1.00 | |
| 104_A | 169_I | 1.514 | 1.00 | |
| 153_G | 246_I | 1.439 | 1.00 | |
| 112_G | 118_A | 1.436 | 1.00 | |
| 43_F | 47_W | 1.434 | 1.00 | |
| 122_R | 173_E | 1.427 | 1.00 | |
| 93_A | 221_I | 1.405 | 0.99 | |
| 187_A | 201_I | 1.392 | 0.99 | |
| 144_V | 155_A | 1.374 | 0.99 | |
| 108_L | 169_I | 1.367 | 0.99 | |
| 234_S | 245_P | 1.364 | 0.99 | |
| 102_I | 206_S | 1.363 | 0.99 | |
| 176_L | 202_T | 1.36 | 0.99 | |
| 99_P | 103_M | 1.358 | 0.99 | |
| 212_T | 216_L | 1.35 | 0.99 | |
| 244_Q | 247_A | 1.348 | 0.99 | |
| 172_T | 213_G | 1.339 | 0.99 | |
| 88_L | 92_W | 1.33 | 0.99 | |
| 110_E | 181_Y | 1.319 | 0.99 | |
| 225_T | 229_L | 1.314 | 0.99 | |
| 168_V | 217_A | 1.309 | 0.99 | |
| 117_L | 120_V | 1.305 | 0.99 | |
| 263_E | 267_L | 1.304 | 0.99 | |
| 193_P | 197_M | 1.303 | 0.99 | |
| 184_R | 188_Y | 1.295 | 0.99 | |
| 179_V | 205_A | 1.294 | 0.99 | |
| 86_S | 250_P | 1.293 | 0.99 | |
| 102_I | 210_I | 1.284 | 0.99 | |
| 89_L | 248_N | 1.264 | 0.99 | |
| 205_A | 208_S | 1.251 | 0.99 | |
| 72_P | 267_L | 1.225 | 0.98 | |
| 252_T | 271_G | 1.219 | 0.98 | |
| 47_W | 51_S | 1.208 | 0.98 | |
| 227_P | 231_T | 1.199 | 0.98 | |
| 95_V | 99_P | 1.199 | 0.98 | |
| 181_Y | 184_R | 1.192 | 0.98 | |
| 87_G | 91_L | 1.177 | 0.98 | |
| 284_I | 288_V | 1.176 | 0.98 | |
| 175_M | 206_S | 1.176 | 0.98 | |
| 70_P | 273_L | 1.162 | 0.97 | |
| 92_W | 96_F | 1.148 | 0.97 | |
| 252_T | 256_F | 1.147 | 0.97 | |
| 198_I | 203_L | 1.143 | 0.97 | |
| 62_L | 66_T | 1.138 | 0.97 | |
| 83_L | 249_L | 1.137 | 0.97 | |
| 91_L | 95_V | 1.135 | 0.97 | |
| 66_T | 69_T | 1.131 | 0.97 | |
| 151_F | 234_S | 1.13 | 0.97 | |
| 116_W | 119_E | 1.129 | 0.97 | |
| 96_F | 157_V | 1.128 | 0.97 | |
| 159_A | 231_T | 1.124 | 0.97 | |
| 165_V | 169_I | 1.116 | 0.96 | |
| 51_S | 269_W | 1.115 | 0.96 | |
| 288_V | 291_A | 1.101 | 0.96 | |
| 112_G | 115_S | 1.1 | 0.96 | |
| 92_W | 95_V | 1.097 | 0.96 | |
| 72_P | 75_E | 1.095 | 0.96 | |
| 120_V | 123_F | 1.09 | 0.96 | |
| 72_P | 263_E | 1.087 | 0.96 | |
| 86_S | 249_L | 1.086 | 0.96 | |
| 48_I | 273_L | 1.084 | 0.96 | |
| 153_G | 157_V | 1.082 | 0.96 | |
| 106_I | 198_I | 1.082 | 0.96 | |
| 248_N | 251_V | 1.071 | 0.95 | |
| 154_W | 158_I | 1.068 | 0.95 | |
| 192_T | 197_M | 1.067 | 0.95 | |
| 97_G | 217_A | 1.066 | 0.95 | |
| 232_A | 246_I | 1.066 | 0.95 | |
| 67_E | 71_P | 1.066 | 0.95 | |
| 182_S | 185_E | 1.064 | 0.95 | |
| 103_M | 107_Y | 1.061 | 0.95 | |
| 181_Y | 185_E | 1.059 | 0.95 | |
| 120_V | 124_I | 1.056 | 0.95 | |
| 97_G | 101_G | 1.054 | 0.95 | |
| 98_T | 210_I | 1.051 | 0.94 | |
| 73_N | 274_I | 1.039 | 0.94 | |
| 247_A | 251_V | 1.039 | 0.94 | |
| 93_A | 160_L | 1.038 | 0.94 | |
| 69_T | 266_Q | 1.037 | 0.94 | |
| 156_G | 228_L | 1.035 | 0.94 | |
| 137_G | 230_F | 1.032 | 0.94 | |
| 106_I | 176_L | 1.027 | 0.94 | |
| 84_A | 87_G | 1.019 | 0.93 | |
| 105_G | 109_A | 1.018 | 0.93 | |
| 168_V | 172_T | 1.016 | 0.93 | |
| 232_A | 235_N | 1.013 | 0.93 | |
| 35_M | 39_A | 1.009 | 0.93 | |
| 70_P | 270_A | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2onkC | 4 | 0.8885 | 100 | 0.428 | Contact Map | 0.759 |
| 3d31C | 2 | 0.9088 | 100 | 0.443 | Contact Map | 0.686 |
| 3rlfG | 1 | 0.9054 | 100 | 0.447 | Contact Map | 0.764 |
| 3rlfF | 1 | 0.9831 | 100 | 0.468 | Contact Map | 0.645 |
| 3tuiA | 4 | 0.7128 | 99.9 | 0.6 | Contact Map | 0.75 |
| 3hd7B | 2 | 0.1689 | 14.7 | 0.954 | Contact Map | 0.543 |
| 2m8rA | 1 | 0.1689 | 14.7 | 0.954 | Contact Map | 0.325 |
| 2dmtA | 1 | 0.0912 | 8.2 | 0.959 | Contact Map | |
| 2da3A | 1 | 0.0912 | 7.8 | 0.959 | Contact Map | |
| 3a02A | 1 | 0.0845 | 7 | 0.96 | Contact Map |
Sequence Conservation (Image Generated using WebLogo v3)