| UniProt: | P0AAG8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10592 | ||
| Length: | 506 (492) | ||
| Sequences: | 13979 | ||
| Seq/Len: | 28.41 |
| MGLA
Paralog alert: 0.93 [within 20: 0.27] - ratio of genomes with paralogs Cluster includes: ALSA ARAG GSIA LSRA MGLA MODF RBSA UUP XYLG YBHF YBIT YEJF YHES YJJK YPHE YTFR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 40_S | 218_E | 4.506 | 1.00 | |
| 18_G | 31_N | 4.398 | 1.00 | |
| 270_N | 281_D | 4.378 | 1.00 | |
| 267_E | 285_D | 4.182 | 1.00 | |
| 30_D | 226_Q | 3.972 | 1.00 | |
| 269_R | 319_T | 3.928 | 1.00 | |
| 290_E | 475_R | 3.708 | 1.00 | |
| 17_S | 69_T | 3.688 | 1.00 | |
| 306_V | 462_I | 3.479 | 1.00 | |
| 69_T | 76_E | 3.391 | 1.00 | |
| 42_H | 220_T | 3.36 | 1.00 | |
| 15_E | 35_K | 3.332 | 1.00 | |
| 268_V | 271_L | 3.315 | 1.00 | |
| 267_E | 321_T | 3.168 | 1.00 | |
| 16_M | 19_I | 3.157 | 1.00 | |
| 319_T | 326_Q | 3.025 | 1.00 | |
| 27_K | 30_D | 2.967 | 1.00 | |
| 307_E | 313_R | 2.863 | 1.00 | |
| 280_R | 483_L | 2.773 | 1.00 | |
| 292_L | 477_L | 2.734 | 1.00 | |
| 15_E | 71_L | 2.635 | 1.00 | |
| 122_D | 125_K | 2.572 | 1.00 | |
| 20_N | 31_N | 2.548 | 1.00 | |
| 43_A | 216_C | 2.538 | 1.00 | |
| 390_I | 400_H | 2.537 | 1.00 | |
| 293_G | 473_T | 2.526 | 1.00 | |
| 339_G | 426_E | 2.517 | 1.00 | |
| 129_E | 132_A | 2.5 | 1.00 | |
| 232_P | 235_G | 2.493 | 1.00 | |
| 323_H | 426_E | 2.489 | 1.00 | |
| 73_Q | 169_K | 2.488 | 1.00 | |
| 268_V | 284_F | 2.45 | 1.00 | |
| 193_R | 214_Q | 2.339 | 1.00 | |
| 127_Y | 144_R | 2.337 | 1.00 | |
| 270_N | 283_S | 2.3 | 1.00 | |
| 145_A | 149_T | 2.279 | 1.00 | |
| 269_R | 321_T | 2.279 | 1.00 | |
| 273_S | 308_T | 2.269 | 1.00 | |
| 56_L | 205_I | 2.255 | 1.00 | |
| 22_S | 27_K | 2.244 | 1.00 | |
| 136_E | 198_R | 2.219 | 1.00 | |
| 18_G | 33_N | 2.214 | 1.00 | |
| 264_V | 267_E | 2.198 | 1.00 | |
| 273_S | 316_S | 2.155 | 1.00 | |
| 463_S | 469_L | 2.115 | 1.00 | |
| 288_K | 426_E | 2.113 | 1.00 | |
| 23_F | 63_Y | 2.058 | 1.00 | |
| 125_K | 129_E | 2.053 | 1.00 | |
| 308_T | 315_K | 2.046 | 1.00 | |
| 272_T | 281_D | 2.026 | 1.00 | |
| 89_G | 169_K | 2.017 | 1.00 | |
| 305_I | 479_M | 1.995 | 1.00 | |
| 451_E | 455_K | 1.992 | 1.00 | |
| 477_L | 487_I | 1.969 | 1.00 | |
| 355_Y | 405_G | 1.958 | 1.00 | |
| 129_E | 167_N | 1.952 | 1.00 | |
| 20_N | 27_K | 1.949 | 1.00 | |
| 306_V | 429_M | 1.937 | 1.00 | |
| 272_T | 317_A | 1.93 | 1.00 | |
| 37_R | 40_S | 1.903 | 1.00 | |
| 220_T | 227_W | 1.835 | 1.00 | |
| 79_F | 88_N | 1.831 | 1.00 | |
| 16_M | 34_L | 1.828 | 1.00 | |
| 263_E | 288_K | 1.825 | 1.00 | |
| 216_C | 233_L | 1.805 | 1.00 | |
| 104_S | 107_D | 1.787 | 1.00 | |
| 286_L | 292_L | 1.782 | 1.00 | |
| 287_H | 290_E | 1.782 | 1.00 | |
| 16_M | 59_L | 1.779 | 1.00 | |
| 461_I | 472_I | 1.758 | 1.00 | |
| 81_S | 84_E | 1.747 | 1.00 | |
| 17_S | 71_L | 1.741 | 1.00 | |
| 128_R | 132_A | 1.737 | 1.00 | |
| 102_Q | 148_G | 1.718 | 1.00 | |
| 131_K | 135_D | 1.717 | 1.00 | |
| 109_M | 165_S | 1.714 | 1.00 | |
| 388_W | 392_S | 1.711 | 1.00 | |
| 277_P | 280_R | 1.711 | 1.00 | |
| 293_G | 469_L | 1.689 | 1.00 | |
| 269_R | 283_S | 1.689 | 1.00 | |
| 192_I | 202_I | 1.683 | 1.00 | |
| 91_S | 163_A | 1.682 | 1.00 | |
| 284_F | 477_L | 1.666 | 1.00 | |
| 38_P | 169_K | 1.664 | 1.00 | |
| 142_D | 145_A | 1.651 | 1.00 | |
| 389_V | 422_L | 1.645 | 1.00 | |
| 20_N | 67_S | 1.622 | 1.00 | |
| 286_L | 458_G | 1.612 | 1.00 | |
| 426_E | 457_K | 1.608 | 1.00 | |
| 359_G | 401_R | 1.607 | 1.00 | |
| 76_E | 79_F | 1.595 | 1.00 | |
| 310_F | 429_M | 1.587 | 1.00 | |
| 392_S | 451_E | 1.574 | 1.00 | |
| 489_D | 492_T | 1.569 | 1.00 | |
| 36_V | 170_I | 1.561 | 1.00 | |
| 146_R | 149_T | 1.553 | 1.00 | |
| 389_V | 418_G | 1.548 | 1.00 | |
| 41_I | 192_I | 1.545 | 1.00 | |
| 231_E | 236_L | 1.542 | 1.00 | |
| 93_V | 173_M | 1.539 | 1.00 | |
| 229_A | 244_M | 1.529 | 1.00 | |
| 18_G | 67_S | 1.528 | 1.00 | |
| 213_F | 234_A | 1.522 | 1.00 | |
| 390_I | 397_T | 1.515 | 1.00 | |
| 270_N | 317_A | 1.51 | 1.00 | |
| 169_K | 200_C | 1.51 | 1.00 | |
| 264_V | 285_D | 1.496 | 1.00 | |
| 407_L | 415_V | 1.494 | 1.00 | |
| 80_H | 84_E | 1.493 | 1.00 | |
| 13_L | 201_G | 1.489 | 1.00 | |
| 218_E | 230_T | 1.489 | 1.00 | |
| 477_L | 484_V | 1.487 | 1.00 | |
| 437_I | 445_I | 1.486 | 1.00 | |
| 486_G | 501_L | 1.48 | 1.00 | |
| 136_E | 194_K | 1.48 | 1.00 | |
| 404_I | 415_V | 1.471 | 1.00 | |
| 399_G | 402_T | 1.463 | 1.00 | |
| 268_V | 309_L | 1.462 | 1.00 | |
| 264_V | 287_H | 1.456 | 1.00 | |
| 17_S | 35_K | 1.448 | 1.00 | |
| 17_S | 33_N | 1.448 | 1.00 | |
| 271_L | 315_K | 1.444 | 1.00 | |
| 21_K | 58_C | 1.443 | 1.00 | |
| 353_Y | 364_I | 1.44 | 1.00 | |
| 133_I | 165_S | 1.431 | 1.00 | |
| 378_D | 381_R | 1.428 | 1.00 | |
| 269_R | 285_D | 1.417 | 1.00 | |
| 288_K | 458_G | 1.414 | 1.00 | |
| 356_L | 360_F | 1.412 | 1.00 | |
| 274_L | 316_S | 1.408 | 1.00 | |
| 125_K | 128_R | 1.383 | 0.99 | |
| 36_V | 42_H | 1.376 | 0.99 | |
| 19_I | 58_C | 1.372 | 0.99 | |
| 387_Q | 400_H | 1.368 | 0.99 | |
| 34_L | 220_T | 1.366 | 0.99 | |
| 60_F | 92_M | 1.363 | 0.99 | |
| 357_D | 360_F | 1.362 | 0.99 | |
| 499_L | 502_A | 1.351 | 0.99 | |
| 343_V | 430_L | 1.346 | 0.99 | |
| 240_K | 243_A | 1.341 | 0.99 | |
| 99_L | 147_V | 1.341 | 0.99 | |
| 151_S | 154_Q | 1.336 | 0.99 | |
| 194_K | 198_R | 1.333 | 0.99 | |
| 286_L | 427_I | 1.33 | 0.99 | |
| 186_N | 214_Q | 1.32 | 0.99 | |
| 196_K | 217_D | 1.316 | 0.99 | |
| 385_D | 388_W | 1.312 | 0.99 | |
| 279_I | 282_V | 1.31 | 0.99 | |
| 268_V | 320_I | 1.309 | 0.99 | |
| 475_R | 487_I | 1.309 | 0.99 | |
| 190_T | 194_K | 1.307 | 0.99 | |
| 21_K | 54_T | 1.297 | 0.99 | |
| 291_I | 449_I | 1.296 | 0.99 | |
| 72_F | 170_I | 1.287 | 0.99 | |
| 62_I | 94_H | 1.272 | 0.99 | |
| 206_S | 212_I | 1.271 | 0.99 | |
| 132_A | 136_E | 1.266 | 0.99 | |
| 194_K | 197_E | 1.262 | 0.99 | |
| 273_S | 313_R | 1.261 | 0.99 | |
| 14_L | 72_F | 1.261 | 0.99 | |
| 363_L | 382_M | 1.253 | 0.99 | |
| 290_E | 474_D | 1.251 | 0.99 | |
| 493_T | 497_E | 1.243 | 0.98 | |
| 387_Q | 391_D | 1.241 | 0.98 | |
| 358_I | 415_V | 1.233 | 0.98 | |
| 359_G | 400_H | 1.23 | 0.98 | |
| 402_T | 406_S | 1.223 | 0.98 | |
| 193_R | 196_K | 1.217 | 0.98 | |
| 110_W | 130_T | 1.217 | 0.98 | |
| 12_Y | 37_R | 1.192 | 0.98 | |
| 71_L | 76_E | 1.189 | 0.98 | |
| 322_L | 427_I | 1.188 | 0.98 | |
| 322_L | 327_I | 1.179 | 0.98 | |
| 127_Y | 131_K | 1.178 | 0.98 | |
| 403_Q | 406_S | 1.176 | 0.98 | |
| 237_T | 240_K | 1.174 | 0.98 | |
| 58_C | 70_I | 1.167 | 0.97 | |
| 384_S | 388_W | 1.163 | 0.97 | |
| 22_S | 67_S | 1.16 | 0.97 | |
| 449_I | 459_I | 1.158 | 0.97 | |
| 271_L | 308_T | 1.157 | 0.97 | |
| 340_F | 427_I | 1.15 | 0.97 | |
| 430_L | 449_I | 1.15 | 0.97 | |
| 490_T | 493_T | 1.149 | 0.97 | |
| 110_W | 126_M | 1.146 | 0.97 | |
| 488_V | 501_L | 1.145 | 0.97 | |
| 56_L | 172_I | 1.141 | 0.97 | |
| 40_S | 217_D | 1.135 | 0.97 | |
| 264_V | 288_K | 1.134 | 0.97 | |
| 31_N | 226_Q | 1.134 | 0.97 | |
| 131_K | 143_P | 1.125 | 0.97 | |
| 134_F | 143_P | 1.122 | 0.97 | |
| 281_D | 483_L | 1.122 | 0.97 | |
| 292_L | 460_I | 1.12 | 0.96 | |
| 23_F | 54_T | 1.119 | 0.96 | |
| 58_C | 65_K | 1.118 | 0.96 | |
| 106_M | 130_T | 1.117 | 0.96 | |
| 56_L | 92_M | 1.116 | 0.96 | |
| 106_M | 127_Y | 1.113 | 0.96 | |
| 20_N | 30_D | 1.11 | 0.96 | |
| 231_E | 235_G | 1.105 | 0.96 | |
| 294_I | 477_L | 1.102 | 0.96 | |
| 361_N | 419_R | 1.1 | 0.96 | |
| 186_N | 190_T | 1.098 | 0.96 | |
| 352_I | 404_I | 1.098 | 0.96 | |
| 16_M | 70_I | 1.095 | 0.96 | |
| 100_V | 111_L | 1.092 | 0.96 | |
| 216_C | 219_V | 1.092 | 0.96 | |
| 274_L | 277_P | 1.086 | 0.96 | |
| 72_F | 90_I | 1.085 | 0.96 | |
| 381_R | 384_S | 1.082 | 0.96 | |
| 383_K | 387_Q | 1.078 | 0.95 | |
| 353_Y | 356_L | 1.078 | 0.95 | |
| 29_L | 32_V | 1.078 | 0.95 | |
| 14_L | 59_L | 1.076 | 0.95 | |
| 341_A | 425_P | 1.074 | 0.95 | |
| 137_L | 161_A | 1.072 | 0.95 | |
| 272_T | 280_R | 1.067 | 0.95 | |
| 91_S | 168_A | 1.066 | 0.95 | |
| 264_V | 321_T | 1.064 | 0.95 | |
| 321_T | 326_Q | 1.063 | 0.95 | |
| 19_I | 65_K | 1.063 | 0.95 | |
| 265_I | 458_G | 1.062 | 0.95 | |
| 101_L | 155_M | 1.062 | 0.95 | |
| 284_F | 305_I | 1.061 | 0.95 | |
| 75_K | 84_E | 1.06 | 0.95 | |
| 155_M | 346_E | 1.06 | 0.95 | |
| 195_L | 200_C | 1.06 | 0.95 | |
| 84_E | 87_E | 1.049 | 0.94 | |
| 494_T | 497_E | 1.049 | 0.94 | |
| 150_L | 158_I | 1.045 | 0.94 | |
| 38_P | 201_G | 1.044 | 0.94 | |
| 167_N | 198_R | 1.031 | 0.94 | |
| 21_K | 63_Y | 1.028 | 0.94 | |
| 265_I | 323_H | 1.027 | 0.94 | |
| 279_I | 308_T | 1.026 | 0.94 | |
| 23_F | 28_A | 1.024 | 0.93 | |
| 43_A | 212_I | 1.022 | 0.93 | |
| 53_S | 57_K | 1.02 | 0.93 | |
| 132_A | 135_D | 1.016 | 0.93 | |
| 135_D | 140_D | 1.008 | 0.93 | |
| 147_V | 158_I | 1.007 | 0.93 | |
| 42_H | 230_T | 1.004 | 0.93 | |
| 295_A | 469_L | 1.003 | 0.93 | |
| 240_K | 244_M | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4finA | 2 | 0.9032 | 100 | 0.23 | Contact Map | 0.754 |
| 3g5uA | 2 | 0.9644 | 100 | 0.246 | Contact Map | 0.65 |
| 4f4cA | 1 | 0.9625 | 100 | 0.251 | Contact Map | 0.709 |
| 1yqtA | 1 | 0.9249 | 100 | 0.287 | Contact Map | 0.641 |
| 2iw3A | 2 | 0.8893 | 100 | 0.299 | Contact Map | 0.72 |
| 3bk7A | 1 | 0.9229 | 100 | 0.3 | Contact Map | 0.62 |
| 3ozxA | 2 | 0.8933 | 100 | 0.302 | Contact Map | 0.674 |
| 3ux8A | 1 | 0.9466 | 100 | 0.317 | Contact Map | 0.589 |
| 3j16B | 1 | 0.9229 | 100 | 0.317 | Contact Map | 0.471 |
| 2vf7A | 3 | 0.9684 | 100 | 0.414 | Contact Map | 0.558 |
Sequence Conservation (Image Generated using WebLogo v3)