| UniProt: | P0A9W3 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12343 | ||
| Length: | 555 (531) | ||
| Sequences: | 15028 | ||
| Seq/Len: | 28.30 |
| YJJK
Paralog alert: 0.93 [within 20: 0.27] - ratio of genomes with paralogs Cluster includes: ALSA ARAG GSIA LSRA MGLA MODF RBSA UUP XYLG YBHF YBIT YEJF YHES YJJK YPHE YTFR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 33_A | 228_W | 5.103 | 1.00 | |
| 10_R | 24_N | 5.015 | 1.00 | |
| 328_N | 341_D | 4.976 | 1.00 | |
| 325_E | 345_S | 4.676 | 1.00 | |
| 23_K | 236_E | 4.615 | 1.00 | |
| 327_S | 379_T | 4.54 | 1.00 | |
| 366_F | 497_I | 4.176 | 1.00 | |
| 9_H | 62_E | 3.998 | 1.00 | |
| 350_A | 510_H | 3.978 | 1.00 | |
| 326_V | 329_L | 3.96 | 1.00 | |
| 35_I | 230_L | 3.801 | 1.00 | |
| 7_T | 28_S | 3.669 | 1.00 | |
| 8_M | 11_V | 3.656 | 1.00 | |
| 325_E | 381_T | 3.548 | 1.00 | |
| 20_H | 23_K | 3.516 | 1.00 | |
| 367_R | 373_E | 3.268 | 1.00 | |
| 36_G | 226_A | 3.025 | 1.00 | |
| 352_V | 512_L | 2.985 | 1.00 | |
| 12_G | 24_N | 2.916 | 1.00 | |
| 326_V | 344_F | 2.903 | 1.00 | |
| 49_L | 215_I | 2.799 | 1.00 | |
| 353_G | 508_A | 2.754 | 1.00 | |
| 328_N | 343_S | 2.736 | 1.00 | |
| 223_D | 245_S | 2.634 | 1.00 | |
| 7_T | 64_R | 2.628 | 1.00 | |
| 331_K | 368_M | 2.569 | 1.00 | |
| 428_V | 438_Q | 2.566 | 1.00 | |
| 10_R | 26_S | 2.529 | 1.00 | |
| 327_S | 381_T | 2.523 | 1.00 | |
| 498_S | 504_L | 2.49 | 1.00 | |
| 368_M | 375_P | 2.469 | 1.00 | |
| 14_V | 20_H | 2.415 | 1.00 | |
| 401_S | 443_G | 2.406 | 1.00 | |
| 322_K | 325_E | 2.393 | 1.00 | |
| 158_A | 162_N | 2.351 | 1.00 | |
| 103_R | 124_E | 2.343 | 1.00 | |
| 330_R | 341_D | 2.342 | 1.00 | |
| 143_Q | 146_R | 2.331 | 1.00 | |
| 66_Q | 182_D | 2.323 | 1.00 | |
| 206_H | 224_N | 2.292 | 1.00 | |
| 15_V | 56_D | 2.272 | 1.00 | |
| 337_L | 340_D | 2.268 | 1.00 | |
| 331_K | 376_D | 2.268 | 1.00 | |
| 366_F | 467_L | 2.264 | 1.00 | |
| 8_M | 27_L | 2.259 | 1.00 | |
| 348_K | 464_N | 2.238 | 1.00 | |
| 70_K | 182_D | 2.225 | 1.00 | |
| 12_G | 20_H | 2.189 | 1.00 | |
| 34_K | 205_L | 2.168 | 1.00 | |
| 330_R | 377_S | 2.136 | 1.00 | |
| 496_V | 507_I | 2.13 | 1.00 | |
| 346_I | 352_V | 2.074 | 1.00 | |
| 379_T | 385_T | 2.056 | 1.00 | |
| 30_F | 33_A | 2.05 | 1.00 | |
| 365_L | 514_Y | 2.032 | 1.00 | |
| 321_D | 348_K | 2.02 | 1.00 | |
| 85_T | 88_E | 2.007 | 1.00 | |
| 72_G | 176_L | 1.999 | 1.00 | |
| 387_K | 464_N | 1.947 | 1.00 | |
| 83_E | 161_A | 1.946 | 1.00 | |
| 8_M | 52_M | 1.939 | 1.00 | |
| 9_H | 64_R | 1.93 | 1.00 | |
| 90_I | 178_L | 1.925 | 1.00 | |
| 230_L | 237_G | 1.902 | 1.00 | |
| 347_P | 350_A | 1.893 | 1.00 | |
| 150_A | 207_D | 1.892 | 1.00 | |
| 327_S | 343_S | 1.868 | 1.00 | |
| 353_G | 504_L | 1.864 | 1.00 | |
| 427_Y | 460_Q | 1.845 | 1.00 | |
| 143_Q | 180_K | 1.845 | 1.00 | |
| 12_G | 60_E | 1.832 | 1.00 | |
| 475_L | 483_L | 1.817 | 1.00 | |
| 145_E | 149_D | 1.812 | 1.00 | |
| 29_F | 183_M | 1.809 | 1.00 | |
| 370_S | 467_L | 1.8 | 1.00 | |
| 351_I | 487_L | 1.799 | 1.00 | |
| 326_V | 380_I | 1.795 | 1.00 | |
| 428_V | 435_G | 1.794 | 1.00 | |
| 74_L | 186_L | 1.793 | 1.00 | |
| 329_L | 375_P | 1.782 | 1.00 | |
| 31_P | 182_D | 1.776 | 1.00 | |
| 426_A | 430_R | 1.748 | 1.00 | |
| 344_F | 512_L | 1.744 | 1.00 | |
| 203_R | 207_D | 1.729 | 1.00 | |
| 10_R | 60_E | 1.714 | 1.00 | |
| 159_K | 162_N | 1.71 | 1.00 | |
| 328_N | 377_S | 1.705 | 1.00 | |
| 332_S | 376_D | 1.699 | 1.00 | |
| 340_D | 518_G | 1.689 | 1.00 | |
| 399_D | 410_G | 1.686 | 1.00 | |
| 445_L | 453_L | 1.679 | 1.00 | |
| 9_H | 28_S | 1.677 | 1.00 | |
| 430_R | 489_E | 1.667 | 1.00 | |
| 403_T | 406_E | 1.658 | 1.00 | |
| 391_V | 468_L | 1.634 | 1.00 | |
| 136_D | 139_N | 1.628 | 1.00 | |
| 9_H | 26_S | 1.623 | 1.00 | |
| 5_V | 211_T | 1.616 | 1.00 | |
| 437_D | 440_K | 1.616 | 1.00 | |
| 29_F | 35_I | 1.606 | 1.00 | |
| 13_K | 51_I | 1.602 | 1.00 | |
| 53_A | 73_Y | 1.601 | 1.00 | |
| 442_V | 453_L | 1.598 | 1.00 | |
| 405_W | 439_G | 1.59 | 1.00 | |
| 322_K | 347_P | 1.586 | 1.00 | |
| 427_Y | 456_A | 1.562 | 1.00 | |
| 13_K | 47_T | 1.548 | 1.00 | |
| 322_K | 345_S | 1.545 | 1.00 | |
| 512_L | 522_F | 1.544 | 1.00 | |
| 147_A | 178_L | 1.538 | 1.00 | |
| 164_S | 167_E | 1.535 | 1.00 | |
| 326_V | 369_I | 1.533 | 1.00 | |
| 327_S | 345_S | 1.529 | 1.00 | |
| 6_Y | 65_P | 1.522 | 1.00 | |
| 339_I | 342_L | 1.507 | 1.00 | |
| 80_L | 160_I | 1.506 | 1.00 | |
| 55_I | 75_P | 1.488 | 1.00 | |
| 273_L | 277_R | 1.479 | 1.00 | |
| 331_K | 373_E | 1.466 | 1.00 | |
| 117_D | 120_K | 1.463 | 1.00 | |
| 226_A | 244_Y | 1.458 | 1.00 | |
| 11_V | 51_I | 1.457 | 1.00 | |
| 402_K | 406_E | 1.442 | 1.00 | |
| 485_N | 489_E | 1.426 | 1.00 | |
| 65_P | 183_M | 1.424 | 1.00 | |
| 27_L | 230_L | 1.422 | 1.00 | |
| 346_I | 493_C | 1.419 | 1.00 | |
| 382_L | 386_V | 1.414 | 1.00 | |
| 441_R | 444_E | 1.405 | 0.99 | |
| 122_A | 157_D | 1.399 | 0.99 | |
| 382_L | 465_M | 1.397 | 0.99 | |
| 440_K | 444_E | 1.387 | 0.99 | |
| 352_V | 495_M | 1.386 | 0.99 | |
| 216_T | 222_L | 1.383 | 0.99 | |
| 163_L | 171_V | 1.368 | 0.99 | |
| 332_S | 337_L | 1.349 | 0.99 | |
| 402_K | 410_G | 1.348 | 0.99 | |
| 322_K | 348_K | 1.34 | 0.99 | |
| 199_A | 224_N | 1.334 | 0.99 | |
| 36_G | 222_L | 1.332 | 0.99 | |
| 14_V | 60_E | 1.331 | 0.99 | |
| 425_R | 438_Q | 1.331 | 0.99 | |
| 348_K | 493_C | 1.328 | 0.99 | |
| 329_L | 368_M | 1.323 | 0.99 | |
| 404_V | 453_L | 1.32 | 0.99 | |
| 24_N | 236_E | 1.316 | 0.99 | |
| 12_G | 23_K | 1.315 | 0.99 | |
| 389_A | 463_G | 1.312 | 0.99 | |
| 346_I | 465_M | 1.311 | 0.99 | |
| 226_A | 229_I | 1.311 | 0.99 | |
| 51_I | 63_A | 1.311 | 0.99 | |
| 423_P | 426_A | 1.31 | 0.99 | |
| 81_N | 92_E | 1.31 | 0.99 | |
| 399_D | 402_K | 1.302 | 0.99 | |
| 141_N | 157_D | 1.294 | 0.99 | |
| 15_V | 47_T | 1.288 | 0.99 | |
| 49_L | 73_Y | 1.283 | 0.99 | |
| 49_L | 185_L | 1.28 | 0.99 | |
| 405_W | 438_Q | 1.275 | 0.99 | |
| 132_I | 137_G | 1.269 | 0.99 | |
| 468_L | 487_L | 1.268 | 0.99 | |
| 330_R | 340_D | 1.266 | 0.99 | |
| 354_I | 512_L | 1.263 | 0.99 | |
| 146_R | 150_A | 1.263 | 0.99 | |
| 168_R | 394_F | 1.262 | 0.99 | |
| 487_L | 494_A | 1.256 | 0.99 | |
| 205_L | 212_V | 1.247 | 0.99 | |
| 199_A | 203_R | 1.245 | 0.98 | |
| 74_L | 176_L | 1.244 | 0.98 | |
| 33_A | 227_G | 1.233 | 0.98 | |
| 505_D | 528_T | 1.231 | 0.98 | |
| 350_A | 509_T | 1.226 | 0.98 | |
| 368_M | 380_I | 1.219 | 0.98 | |
| 22_L | 25_I | 1.216 | 0.98 | |
| 50_R | 55_I | 1.213 | 0.98 | |
| 243_N | 246_S | 1.213 | 0.98 | |
| 242_G | 247_W | 1.212 | 0.98 | |
| 407_E | 457_K | 1.207 | 0.98 | |
| 425_R | 429_G | 1.205 | 0.98 | |
| 422_M | 426_A | 1.202 | 0.98 | |
| 246_S | 250_Q | 1.197 | 0.98 | |
| 202_E | 224_N | 1.191 | 0.98 | |
| 11_V | 58_D | 1.185 | 0.98 | |
| 46_S | 50_R | 1.184 | 0.98 | |
| 120_K | 143_Q | 1.184 | 0.98 | |
| 51_I | 58_D | 1.177 | 0.98 | |
| 388_L | 465_M | 1.176 | 0.98 | |
| 6_Y | 183_M | 1.175 | 0.98 | |
| 504_L | 508_A | 1.17 | 0.97 | |
| 145_E | 156_W | 1.169 | 0.97 | |
| 91_E | 144_L | 1.168 | 0.97 | |
| 87_R | 144_L | 1.161 | 0.97 | |
| 321_D | 347_P | 1.16 | 0.97 | |
| 31_P | 211_T | 1.16 | 0.97 | |
| 467_L | 495_M | 1.159 | 0.97 | |
| 72_G | 181_P | 1.158 | 0.97 | |
| 470_E | 499_H | 1.157 | 0.97 | |
| 203_R | 206_H | 1.151 | 0.97 | |
| 526_N | 529_E | 1.139 | 0.97 | |
| 15_V | 21_I | 1.138 | 0.97 | |
| 8_M | 63_A | 1.138 | 0.97 | |
| 362_K | 470_E | 1.137 | 0.97 | |
| 344_F | 365_L | 1.137 | 0.97 | |
| 339_I | 368_M | 1.134 | 0.97 | |
| 95_S | 99_N | 1.131 | 0.97 | |
| 238_I | 254_R | 1.127 | 0.97 | |
| 398_M | 442_V | 1.124 | 0.97 | |
| 416_K | 419_N | 1.112 | 0.96 | |
| 276_V | 291_L | 1.106 | 0.96 | |
| 330_R | 337_L | 1.106 | 0.96 | |
| 262_E | 266_R | 1.105 | 0.96 | |
| 82_P | 168_R | 1.104 | 0.96 | |
| 160_I | 171_V | 1.097 | 0.96 | |
| 151_L | 174_C | 1.097 | 0.96 | |
| 370_S | 390_S | 1.096 | 0.96 | |
| 14_V | 59_I | 1.094 | 0.96 | |
| 354_I | 365_L | 1.091 | 0.96 | |
| 120_K | 124_E | 1.088 | 0.96 | |
| 428_V | 433_F | 1.081 | 0.95 | |
| 100_A | 128_L | 1.08 | 0.95 | |
| 363_S | 393_Q | 1.079 | 0.95 | |
| 129_E | 133_Q | 1.079 | 0.95 | |
| 6_Y | 52_M | 1.074 | 0.95 | |
| 13_K | 56_D | 1.071 | 0.95 | |
| 268_S | 271_K | 1.057 | 0.95 | |
| 29_F | 211_T | 1.056 | 0.95 | |
| 480_L | 500_D | 1.055 | 0.95 | |
| 355_I | 504_L | 1.051 | 0.94 | |
| 322_K | 381_T | 1.051 | 0.94 | |
| 13_K | 59_I | 1.051 | 0.94 | |
| 389_A | 458_L | 1.044 | 0.94 | |
| 405_W | 424_S | 1.042 | 0.94 | |
| 404_V | 435_G | 1.036 | 0.94 | |
| 406_E | 409_S | 1.034 | 0.94 | |
| 83_E | 159_K | 1.033 | 0.94 | |
| 363_S | 469_D | 1.031 | 0.94 | |
| 358_N | 499_H | 1.028 | 0.94 | |
| 176_L | 184_L | 1.027 | 0.94 | |
| 85_T | 159_K | 1.016 | 0.93 | |
| 155_D | 158_A | 1.015 | 0.93 | |
| 35_I | 213_V | 1.012 | 0.93 | |
| 163_L | 167_E | 1.01 | 0.93 | |
| 34_K | 212_V | 1.006 | 0.93 | |
| 142_V | 146_R | 1.005 | 0.93 | |
| 25_I | 237_G | 1.003 | 0.93 | |
| 368_M | 373_E | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4finA | 2 | 1 | 100 | 0.158 | Contact Map | 0.762 |
| 2iw3A | 2 | 0.7982 | 100 | 0.326 | Contact Map | 0.749 |
| 3g5uA | 2 | 0.9009 | 100 | 0.35 | Contact Map | 0.664 |
| 4f4cA | 1 | 0.9009 | 100 | 0.353 | Contact Map | 0.747 |
| 1yqtA | 1 | 0.8414 | 100 | 0.362 | Contact Map | 0.683 |
| 3bk7A | 1 | 0.8739 | 100 | 0.366 | Contact Map | 0.644 |
| 3ozxA | 2 | 0.8685 | 100 | 0.371 | Contact Map | 0.714 |
| 3j16B | 1 | 0.8811 | 100 | 0.385 | Contact Map | 0.476 |
| 3ux8A | 1 | 0.8342 | 100 | 0.428 | Contact Map | 0.612 |
| 2vf7A | 3 | 0.8288 | 100 | 0.532 | Contact Map | 0.615 |
Sequence Conservation (Image Generated using WebLogo v3)