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YBHF - Uncharacterized ABC transporter ATP-binding protein YbhF
UniProt: P0A9U1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13314
Length: 578 (543)
Sequences: 14289
Seq/Len: 26.31
YBHF
Paralog alert: 0.93 [within 20: 0.26] - ratio of genomes with paralogs
Cluster includes: ALSA ARAG GSIA LSRA MGLA MODF RBSA UUP XYLG YBHF YBIT YEJF YHES YJJK YPHE YTFR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
34_Y 206_D 4.229 1.00
24_A 214_E 4.058 1.00
10_G 25_P 3.54 1.00
36_T 208_L 3.272 1.00
9_N 63_S 2.937 1.00
63_S 70_D 2.761 1.00
37_G 204_C 2.735 1.00
7_T 29_T 2.719 1.00
67_I 158_K 2.658 1.00
8_L 11_L 2.452 1.00
21_P 24_A 2.407 1.00
81_V 158_K 2.289 1.00
94_D 137_G 2.119 1.00
12_E 25_P 2.11 1.00
7_T 65_T 2.003 1.00
32_A 158_K 1.987 1.00
50_M 194_S 1.979 1.00
35_V 181_V 1.887 1.00
10_G 27_D 1.828 1.00
98_M 116_K 1.791 1.00
5_V 190_L 1.787 1.00
30_I 159_V 1.762 1.00
83_G 152_T 1.747 1.00
66_V 159_V 1.719 1.00
14_R 21_P 1.679 1.00
91_L 136_A 1.665 1.00
25_P 214_E 1.651 1.00
28_C 208_L 1.636 1.00
85_M 162_L 1.609 1.00
98_M 119_F 1.596 1.00
15_F 57_L 1.583 1.00
36_T 218_Q 1.582 1.00
98_M 133_G 1.581 1.00
31_H 206_D 1.577 1.00
94_D 135_L 1.565 1.00
12_E 21_P 1.542 1.00
8_L 28_C 1.512 1.00
98_M 132_T 1.507 1.00
31_H 34_Y 1.483 1.00
26_L 215_L 1.482 1.00
32_A 190_L 1.445 1.00
99_E 112_G 1.442 1.00
92_Y 103_L 1.439 1.00
93_E 144_K 1.435 1.00
96_T 135_L 1.412 1.00
93_E 137_G 1.405 0.99
9_N 65_T 1.381 0.99
36_T 206_D 1.38 0.99
96_T 99_E 1.363 0.99
31_H 190_L 1.361 0.99
34_Y 205_R 1.361 0.99
83_G 157_P 1.352 0.99
29_T 218_Q 1.339 0.99
8_L 53_L 1.297 0.99
29_T 206_D 1.279 0.99
6_I 159_V 1.278 0.99
27_D 215_L 1.261 0.99
83_G 155_G 1.248 0.99
100_N 151_C 1.246 0.98
50_M 161_L 1.236 0.98
35_V 185_A 1.235 0.98
35_V 182_H 1.231 0.98
12_E 61_S 1.23 0.98
98_M 102_N 1.212 0.98
90_G 144_K 1.201 0.98
90_G 410_K 1.198 0.98
39_V 198_L 1.19 0.98
35_V 203_Q 1.189 0.98
78_L 155_G 1.185 0.98
10_G 61_S 1.18 0.98
49_L 210_M 1.175 0.98
30_I 190_L 1.174 0.98
9_N 29_T 1.163 0.97
41_P 494_L 1.15 0.97
89_F 148_G 1.15 0.97
35_V 191_I 1.144 0.97
5_V 159_V 1.141 0.97
36_T 192_L 1.136 0.97
54_A 161_L 1.135 0.97
92_Y 137_G 1.135 0.97
90_G 155_G 1.129 0.97
24_A 212_E 1.128 0.97
81_V 156_E 1.12 0.96
91_L 144_K 1.118 0.96
9_N 27_D 1.111 0.96
26_L 210_M 1.108 0.96
90_G 148_G 1.108 0.96
38_L 208_L 1.105 0.96
21_P 214_E 1.102 0.96
30_I 36_T 1.101 0.96
92_Y 460_E 1.101 0.96
17_G 453_I 1.096 0.96
98_M 101_L 1.089 0.96
98_M 110_V 1.085 0.96
31_H 218_Q 1.082 0.96
34_Y 218_Q 1.082 0.96
90_G 504_N 1.081 0.95
94_D 414_Y 1.075 0.95
85_M 152_T 1.068 0.95
11_L 52_M 1.067 0.95
96_T 133_G 1.061 0.95
94_D 533_Y 1.061 0.95
94_D 416_N 1.06 0.95
56_L 86_P 1.059 0.95
90_G 417_L 1.054 0.95
94_D 424_R 1.054 0.95
98_M 107_L 1.051 0.94
98_M 120_A 1.049 0.94
13_K 52_M 1.049 0.94
41_P 211_N 1.047 0.94
72_I 227_T 1.044 0.94
30_I 208_L 1.04 0.94
94_D 477_H 1.04 0.94
53_L 192_L 1.04 0.94
94_D 417_L 1.039 0.94
65_T 455_S 1.038 0.94
100_N 136_A 1.034 0.94
99_E 102_N 1.033 0.94
92_Y 378_L 1.03 0.94
16_P 453_I 1.03 0.94
6_I 66_V 1.03 0.94
88_K 489_S 1.025 0.93
41_P 231_R 1.024 0.93
54_A 84_Y 1.022 0.93
94_D 521_D 1.018 0.93
92_Y 414_Y 1.016 0.93
80_A 155_G 1.015 0.93
90_G 193_W 1.015 0.93
98_M 115_R 1.013 0.93
35_V 205_R 1.012 0.93
75_D 231_R 1.012 0.93
95_L 155_G 1.01 0.93
8_L 208_L 1.008 0.93
9_N 387_L 1.008 0.93
31_H 124_E 1.007 0.93
92_Y 417_L 1.007 0.93
65_T 443_R 1.006 0.93
13_K 48_T 1.005 0.93
92_Y 415_G 1.004 0.93
90_G 533_Y 1.004 0.93
39_V 521_D 1.004 0.93
97_V 147_L 1.003 0.93
21_P 420_E 1 0.92
84_Y 155_G 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4finA20.88581000.269Contact Map0.57
3g5uA20.96711000.269Contact Map0.53
4f4cA10.94811000.278Contact Map0.572
1yqtA10.84261000.342Contact Map0.54
2iw3A20.76471000.345Contact Map0.586
3bk7A10.84261000.348Contact Map0.522
3ozxA20.83221000.35Contact Map0.511
3j16B10.83561000.363Contact Map0.411
3ux8A10.8271000.367Contact Map0.412
2vf7A30.82871000.47Contact Map0.01
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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