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OPENSEQ.org
GLXR - HYI
UniProt: P77161 - P30147
Length: 550
Sequences: 497
Seq/Len: 0.91
I_Prob: 0.00
GLXR - 2-hydroxy-3-oxopropionate reductase
Paralog alert: 0.78 [within 20: 0.06] - ratio of genomes with paralogs
Cluster includes: GARR GLXR YGBJ YIHU 		HYI - Hydroxypyruvate isomerase
Paralog alert: 0.70 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: END4 FRLC HYI SGBU ULAE YCJR YGBM
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1nvmBFHD:AECGContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
24_H 3_R 1.08 0.00
111_G 98_G 1.01 0.00
272_S 153_F 0.97 0.00
88_T 95_R 0.97 0.00
142_F 12_F 0.92 0.00
253_L 99_N 0.89 0.00
88_T 137_D 0.88 0.00
57_D 219_I 0.88 0.00
243_L 186_E 0.86 0.00
215_E 17_F 0.85 0.00
137_G 233_Y 0.84 0.00
26_L 212_G 0.83 0.00
94_S 142_I 0.83 0.00
164_D 173_L 0.82 0.00
60_F 205_I 0.82 0.00
19_L 145_I 0.82 0.00
77_N 19_A 0.82 0.00
280_V 59_H 0.82 0.00
143_E 131_N 0.82 0.00
39_L 194_T 0.81 0.00
262_L 18_L 0.81 0.00
54_E 50_A 0.80 0.00
115_L 124_E 0.80 0.00
33_P 124_E 0.80 0.00
46_V 239_C 0.80 0.00
81_K 25_A 0.78 0.00
48_T 117_Q 0.77 0.00
44_V 174_K 0.77 0.00
104_A 127_R 0.77 0.00
184_S 114_S 0.77 0.00
108_N 85_D 0.76 0.00
59_I 226_K 0.76 0.00
6_I 26_Q 0.76 0.00
60_F 116_E 0.76 0.00
71_E 234_N 0.75 0.00
259_C 12_F 0.75 0.00
202_Q 124_E 0.75 0.00
51_Q 47_H 0.75 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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