| UniProt: | P77161 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13265 | ||
| Length: | 292 (285) | ||
| Sequences: | 4711 | ||
| Seq/Len: | 16.53 |
| GLXR
Paralog alert: 0.78 [within 20: 0.06] - ratio of genomes with paralogs Cluster includes: GARR GLXR YGBJ YIHU |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 139_E | 143_E | 3.956 | 1.00 | |
| 70_E | 102_R | 3.508 | 1.00 | |
| 146_K | 150_E | 3.494 | 1.00 | |
| 27_H | 46_V | 2.849 | 1.00 | |
| 113_D | 144_R | 2.7 | 1.00 | |
| 47_E | 51_Q | 2.686 | 1.00 | |
| 4_G | 52_V | 2.68 | 1.00 | |
| 36_D | 40_S | 2.596 | 1.00 | |
| 2_K | 25_Q | 2.536 | 1.00 | |
| 113_D | 141_V | 2.493 | 1.00 | |
| 143_E | 146_K | 2.45 | 1.00 | |
| 39_L | 45_S | 2.372 | 1.00 | |
| 88_T | 145_V | 2.348 | 1.00 | |
| 17_I | 41_L | 2.305 | 1.00 | |
| 20_A | 43_A | 2.303 | 1.00 | |
| 107_V | 112_G | 2.14 | 1.00 | |
| 233_A | 273_Q | 2.107 | 1.00 | |
| 35_A | 45_S | 2.067 | 1.00 | |
| 105_R | 109_E | 1.988 | 1.00 | |
| 80_T | 107_V | 1.952 | 1.00 | |
| 106_Q | 109_E | 1.936 | 1.00 | |
| 191_S | 284_E | 1.91 | 1.00 | |
| 139_E | 158_L | 1.908 | 1.00 | |
| 61_I | 89_I | 1.892 | 1.00 | |
| 50_R | 54_E | 1.856 | 1.00 | |
| 62_M | 92_M | 1.845 | 1.00 | |
| 115_L | 137_G | 1.822 | 1.00 | |
| 48_T | 51_Q | 1.795 | 1.00 | |
| 28_V | 43_A | 1.79 | 1.00 | |
| 196_D | 199_R | 1.775 | 1.00 | |
| 210_S | 215_E | 1.752 | 1.00 | |
| 133_I | 152_L | 1.751 | 1.00 | |
| 98_I | 248_A | 1.737 | 1.00 | |
| 245_S | 248_A | 1.705 | 1.00 | |
| 115_L | 142_F | 1.703 | 1.00 | |
| 108_N | 138_D | 1.695 | 1.00 | |
| 53_T | 82_A | 1.675 | 1.00 | |
| 25_Q | 44_V | 1.673 | 1.00 | |
| 88_T | 141_V | 1.672 | 1.00 | |
| 57_D | 84_L | 1.664 | 1.00 | |
| 142_F | 146_K | 1.656 | 1.00 | |
| 18_N | 21_R | 1.652 | 1.00 | |
| 113_D | 138_D | 1.643 | 1.00 | |
| 170_V | 241_L | 1.598 | 1.00 | |
| 74_F | 106_Q | 1.59 | 1.00 | |
| 13_T | 37_E | 1.586 | 1.00 | |
| 198_V | 202_Q | 1.575 | 1.00 | |
| 52_V | 56_S | 1.574 | 1.00 | |
| 83_S | 87_K | 1.571 | 1.00 | |
| 24_H | 151_L | 1.57 | 1.00 | |
| 190_A | 200_V | 1.57 | 1.00 | |
| 73_L | 89_I | 1.566 | 1.00 | |
| 271_G | 274_L | 1.533 | 1.00 | |
| 60_F | 92_M | 1.531 | 1.00 | |
| 90_V | 145_V | 1.526 | 1.00 | |
| 257_A | 261_E | 1.519 | 1.00 | |
| 84_L | 87_K | 1.519 | 1.00 | |
| 22_A | 151_L | 1.504 | 1.00 | |
| 62_M | 119_V | 1.503 | 1.00 | |
| 104_A | 162_N | 1.499 | 1.00 | |
| 138_D | 141_V | 1.494 | 1.00 | |
| 233_A | 272_S | 1.477 | 1.00 | |
| 233_A | 267_A | 1.471 | 1.00 | |
| 4_G | 56_S | 1.468 | 1.00 | |
| 133_I | 153_G | 1.458 | 1.00 | |
| 18_N | 129_G | 1.458 | 1.00 | |
| 104_A | 108_N | 1.458 | 1.00 | |
| 36_D | 39_L | 1.452 | 1.00 | |
| 115_L | 135_V | 1.422 | 1.00 | |
| 219_E | 223_K | 1.382 | 0.99 | |
| 49_A | 82_A | 1.38 | 0.99 | |
| 27_H | 55_A | 1.369 | 0.99 | |
| 65_D | 68_Q | 1.361 | 0.99 | |
| 33_P | 36_D | 1.347 | 0.99 | |
| 88_T | 144_R | 1.347 | 0.99 | |
| 102_R | 106_Q | 1.346 | 0.99 | |
| 105_R | 108_N | 1.34 | 0.99 | |
| 178_L | 182_A | 1.335 | 0.99 | |
| 205_M | 215_E | 1.326 | 0.99 | |
| 232_I | 266_C | 1.323 | 0.99 | |
| 115_L | 145_V | 1.31 | 0.99 | |
| 145_V | 149_F | 1.303 | 0.99 | |
| 50_R | 82_A | 1.293 | 0.99 | |
| 142_F | 158_L | 1.283 | 0.99 | |
| 193_A | 249_L | 1.274 | 0.99 | |
| 159_V | 168_C | 1.273 | 0.99 | |
| 5_F | 15_M | 1.257 | 0.99 | |
| 27_H | 44_V | 1.249 | 0.99 | |
| 51_Q | 54_E | 1.243 | 0.98 | |
| 81_K | 110_L | 1.242 | 0.98 | |
| 246_A | 253_L | 1.24 | 0.98 | |
| 247_K | 257_A | 1.234 | 0.98 | |
| 161_G | 164_D | 1.212 | 0.98 | |
| 21_R | 41_L | 1.203 | 0.98 | |
| 117_A | 133_I | 1.189 | 0.98 | |
| 55_A | 84_L | 1.177 | 0.98 | |
| 6_I | 49_A | 1.175 | 0.98 | |
| 20_A | 42_G | 1.171 | 0.98 | |
| 92_M | 133_I | 1.169 | 0.97 | |
| 83_S | 112_G | 1.168 | 0.97 | |
| 252_N | 257_A | 1.167 | 0.97 | |
| 67_P | 71_E | 1.163 | 0.97 | |
| 260_Q | 264_N | 1.162 | 0.97 | |
| 100_T | 114_Y | 1.161 | 0.97 | |
| 123_E | 127_R | 1.15 | 0.97 | |
| 116_D | 163_G | 1.149 | 0.97 | |
| 130_T | 154_K | 1.14 | 0.97 | |
| 16_A | 26_L | 1.138 | 0.97 | |
| 5_F | 16_A | 1.134 | 0.97 | |
| 14_P | 127_R | 1.133 | 0.97 | |
| 60_F | 90_V | 1.126 | 0.97 | |
| 258_T | 261_E | 1.123 | 0.97 | |
| 75_G | 78_G | 1.122 | 0.97 | |
| 177_A | 239_L | 1.119 | 0.96 | |
| 66_T | 99_E | 1.111 | 0.96 | |
| 126_A | 131_L | 1.108 | 0.96 | |
| 30_T | 34_V | 1.107 | 0.96 | |
| 120_S | 134_M | 1.107 | 0.96 | |
| 92_M | 152_L | 1.107 | 0.96 | |
| 5_F | 60_F | 1.106 | 0.96 | |
| 107_V | 114_Y | 1.105 | 0.96 | |
| 83_S | 89_I | 1.101 | 0.96 | |
| 87_K | 112_G | 1.097 | 0.96 | |
| 37_E | 40_S | 1.084 | 0.96 | |
| 66_T | 96_S | 1.082 | 0.96 | |
| 58_I | 148_L | 1.076 | 0.95 | |
| 236_Q | 267_A | 1.075 | 0.95 | |
| 177_A | 235_H | 1.073 | 0.95 | |
| 274_L | 281_Q | 1.072 | 0.95 | |
| 138_D | 161_G | 1.069 | 0.95 | |
| 201_R | 218_G | 1.065 | 0.95 | |
| 60_F | 148_L | 1.059 | 0.95 | |
| 100_T | 166_Q | 1.057 | 0.95 | |
| 96_S | 99_E | 1.052 | 0.95 | |
| 135_V | 142_F | 1.048 | 0.94 | |
| 188_L | 192_K | 1.048 | 0.94 | |
| 18_N | 152_L | 1.048 | 0.94 | |
| 136_G | 165_G | 1.046 | 0.94 | |
| 58_I | 88_T | 1.045 | 0.94 | |
| 187_L | 201_R | 1.04 | 0.94 | |
| 15_M | 152_L | 1.034 | 0.94 | |
| 267_A | 272_S | 1.034 | 0.94 | |
| 46_V | 51_Q | 1.024 | 0.93 | |
| 178_L | 255_N | 1.018 | 0.93 | |
| 76_E | 81_K | 1.016 | 0.93 | |
| 2_K | 27_H | 1.014 | 0.93 | |
| 141_V | 145_V | 1.014 | 0.93 | |
| 120_S | 172_N | 1.012 | 0.93 | |
| 230_F | 234_L | 1.009 | 0.93 | |
| 143_E | 158_L | 1.004 | 0.93 | |
| 33_P | 47_E | 1.002 | 0.92 | |
| 122_G | 125_G | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pefA | 8 | 0.976 | 100 | 0.348 | Contact Map | 0.824 |
| 3ckyA | 4 | 1 | 100 | 0.35 | Contact Map | 0.805 |
| 1vpdA | 1 | 1 | 100 | 0.353 | Contact Map | 0.76 |
| 3pduA | 8 | 0.976 | 100 | 0.356 | Contact Map | 0.763 |
| 3dojA | 1 | 0.9863 | 100 | 0.358 | Contact Map | 0.799 |
| 4dllA | 2 | 0.9863 | 100 | 0.363 | Contact Map | 0.756 |
| 1yb4A | 2 | 0.9966 | 100 | 0.364 | Contact Map | 0.797 |
| 2h78A | 1 | 0.9966 | 100 | 0.366 | Contact Map | 0.723 |
| 2uyyA | 4 | 0.976 | 100 | 0.367 | Contact Map | 0.804 |
| 2gf2A | 4 | 0.9863 | 100 | 0.37 | Contact Map | 0.764 |
Sequence Conservation (Image Generated using WebLogo v3)