| UniProt: | P0A6C1 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10651 | ||
| Length: | 285 (277) | ||
| Sequences: | 5298 | ||
| Seq/Len: | 19.13 |
| END4
Paralog alert: 0.69 [within 20: 0.15] - ratio of genomes with paralogs Cluster includes: END4 FRLC HYI SGBU ULAE YCJR YGBM |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 240_G | 243_A | 3.544 | 1.00 | |
| 219_D | 235_G | 3.488 | 1.00 | |
| 53_K | 57_E | 3.457 | 1.00 | |
| 175_G | 213_R | 3.243 | 1.00 | |
| 92_I | 136_K | 3.085 | 1.00 | |
| 19_I | 59_Y | 2.989 | 1.00 | |
| 28_A | 257_P | 2.987 | 1.00 | |
| 96_Q | 136_K | 2.893 | 1.00 | |
| 127_A | 167_G | 2.79 | 1.00 | |
| 85_E | 89_D | 2.7 | 1.00 | |
| 54_A | 58_K | 2.698 | 1.00 | |
| 163_A | 167_G | 2.548 | 1.00 | |
| 195_E | 198_K | 2.422 | 1.00 | |
| 141_T | 175_G | 2.335 | 1.00 | |
| 19_I | 23_E | 2.31 | 1.00 | |
| 15_A | 55_A | 2.3 | 1.00 | |
| 201_A | 247_I | 2.246 | 1.00 | |
| 141_T | 213_R | 2.158 | 1.00 | |
| 88_R | 132_I | 2.156 | 1.00 | |
| 204_A | 210_K | 2.127 | 1.00 | |
| 135_D | 170_D | 2.127 | 1.00 | |
| 84_L | 129_S | 2.015 | 1.00 | |
| 13_G | 16_N | 1.966 | 1.00 | |
| 55_A | 59_Y | 1.966 | 1.00 | |
| 269_A | 273_A | 1.962 | 1.00 | |
| 143_V | 213_R | 1.944 | 1.00 | |
| 55_A | 58_K | 1.941 | 1.00 | |
| 105_L | 143_V | 1.878 | 1.00 | |
| 124_A | 167_G | 1.858 | 1.00 | |
| 123_L | 163_A | 1.845 | 1.00 | |
| 98_C | 103_L | 1.84 | 1.00 | |
| 247_I | 250_D | 1.78 | 1.00 | |
| 51_E | 54_A | 1.76 | 1.00 | |
| 121_D | 124_A | 1.759 | 1.00 | |
| 89_D | 93_D | 1.744 | 1.00 | |
| 22_A | 59_Y | 1.74 | 1.00 | |
| 46_T | 100_Q | 1.727 | 1.00 | |
| 123_L | 167_G | 1.715 | 1.00 | |
| 201_A | 250_D | 1.694 | 1.00 | |
| 56_C | 63_S | 1.686 | 1.00 | |
| 273_A | 277_A | 1.671 | 1.00 | |
| 93_D | 96_Q | 1.654 | 1.00 | |
| 215_M | 248_M | 1.653 | 1.00 | |
| 48_T | 51_E | 1.623 | 1.00 | |
| 162_A | 166_D | 1.608 | 1.00 | |
| 15_A | 51_E | 1.592 | 1.00 | |
| 134_L | 174_V | 1.583 | 1.00 | |
| 159_E | 202_D | 1.582 | 1.00 | |
| 146_N | 183_A | 1.575 | 1.00 | |
| 125_R | 128_E | 1.569 | 1.00 | |
| 143_V | 177_C | 1.566 | 1.00 | |
| 49_I | 100_Q | 1.566 | 1.00 | |
| 198_K | 202_D | 1.564 | 1.00 | |
| 50_D | 100_Q | 1.551 | 1.00 | |
| 175_G | 211_Y | 1.549 | 1.00 | |
| 138_Q | 170_D | 1.544 | 1.00 | |
| 19_I | 55_A | 1.543 | 1.00 | |
| 81_T | 85_E | 1.533 | 1.00 | |
| 127_A | 131_N | 1.509 | 1.00 | |
| 170_D | 173_R | 1.5 | 1.00 | |
| 246_W | 250_D | 1.487 | 1.00 | |
| 138_Q | 173_R | 1.483 | 1.00 | |
| 18_A | 59_Y | 1.472 | 1.00 | |
| 26_A | 260_L | 1.468 | 1.00 | |
| 221_K | 232_H | 1.463 | 1.00 | |
| 131_N | 169_E | 1.459 | 1.00 | |
| 21_A | 26_A | 1.45 | 1.00 | |
| 134_L | 168_V | 1.436 | 1.00 | |
| 15_A | 58_K | 1.433 | 1.00 | |
| 95_M | 137_T | 1.427 | 1.00 | |
| 118_S | 121_D | 1.421 | 1.00 | |
| 127_A | 168_V | 1.415 | 1.00 | |
| 124_A | 128_E | 1.409 | 1.00 | |
| 3_Y | 62_T | 1.403 | 0.99 | |
| 219_D | 237_G | 1.4 | 0.99 | |
| 88_R | 92_I | 1.399 | 0.99 | |
| 27_T | 276_K | 1.394 | 0.99 | |
| 50_D | 54_A | 1.387 | 0.99 | |
| 274_W | 277_A | 1.369 | 0.99 | |
| 96_Q | 99_E | 1.365 | 0.99 | |
| 274_W | 278_Q | 1.362 | 0.99 | |
| 128_E | 131_N | 1.35 | 0.99 | |
| 201_A | 205_R | 1.316 | 0.99 | |
| 18_A | 55_A | 1.306 | 0.99 | |
| 54_A | 57_E | 1.305 | 0.99 | |
| 91_F | 133_A | 1.3 | 0.99 | |
| 162_A | 202_D | 1.3 | 0.99 | |
| 92_I | 96_Q | 1.291 | 0.99 | |
| 242_D | 246_W | 1.277 | 0.99 | |
| 20_R | 23_E | 1.272 | 0.99 | |
| 197_E | 243_A | 1.267 | 0.99 | |
| 105_L | 141_T | 1.258 | 0.99 | |
| 89_D | 92_I | 1.24 | 0.98 | |
| 197_E | 201_A | 1.239 | 0.98 | |
| 85_E | 132_I | 1.233 | 0.98 | |
| 83_A | 86_K | 1.232 | 0.98 | |
| 51_E | 55_A | 1.23 | 0.98 | |
| 95_M | 140_V | 1.226 | 0.98 | |
| 166_D | 211_Y | 1.219 | 0.98 | |
| 119_E | 160_H | 1.215 | 0.98 | |
| 169_E | 172_S | 1.212 | 0.98 | |
| 247_I | 251_D | 1.209 | 0.98 | |
| 200_F | 251_D | 1.203 | 0.98 | |
| 16_N | 19_I | 1.2 | 0.98 | |
| 120_E | 124_A | 1.196 | 0.98 | |
| 156_F | 160_H | 1.183 | 0.98 | |
| 138_Q | 172_S | 1.17 | 0.97 | |
| 56_C | 61_Y | 1.165 | 0.97 | |
| 272_I | 276_K | 1.156 | 0.97 | |
| 92_I | 132_I | 1.156 | 0.97 | |
| 15_A | 19_I | 1.153 | 0.97 | |
| 53_K | 100_Q | 1.149 | 0.97 | |
| 98_C | 106_L | 1.149 | 0.97 | |
| 180_T | 244_F | 1.146 | 0.97 | |
| 243_A | 247_I | 1.129 | 0.97 | |
| 84_L | 128_E | 1.128 | 0.97 | |
| 18_A | 56_C | 1.124 | 0.97 | |
| 198_K | 201_A | 1.12 | 0.96 | |
| 84_L | 125_R | 1.11 | 0.96 | |
| 120_E | 163_A | 1.109 | 0.96 | |
| 22_A | 60_H | 1.101 | 0.96 | |
| 162_A | 203_F | 1.097 | 0.96 | |
| 21_A | 29_F | 1.092 | 0.96 | |
| 163_A | 166_D | 1.089 | 0.96 | |
| 161_L | 176_V | 1.087 | 0.96 | |
| 200_F | 247_I | 1.085 | 0.96 | |
| 236_E | 270_E | 1.073 | 0.95 | |
| 148_A | 185_A | 1.064 | 0.95 | |
| 95_M | 136_K | 1.06 | 0.95 | |
| 94_E | 106_L | 1.058 | 0.95 | |
| 159_E | 163_A | 1.036 | 0.94 | |
| 86_K | 89_D | 1.033 | 0.94 | |
| 157_K | 160_H | 1.028 | 0.94 | |
| 105_L | 213_R | 1.024 | 0.93 | |
| 99_E | 139_G | 1.02 | 0.93 | |
| 178_I | 200_F | 1.016 | 0.93 | |
| 82_E | 86_K | 1.015 | 0.93 | |
| 165_I | 211_Y | 1.013 | 0.93 | |
| 178_I | 183_A | 1.009 | 0.93 | |
| 69_H | 109_H | 1.008 | 0.93 | |
| 132_I | 135_D | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1qtwA | 1 | 0.9965 | 100 | 0.216 | Contact Map | 0.633 |
| 4hnoA | 1 | 0.993 | 100 | 0.227 | Contact Map | 0.673 |
| 3aalA | 1 | 0.9754 | 100 | 0.245 | Contact Map | 0.571 |
| 2hk0A | 4 | 0.8842 | 100 | 0.276 | Contact Map | 0.707 |
| 2qulA | 4 | 0.8807 | 100 | 0.282 | Contact Map | 0.744 |
| 3aamA | 1 | 0.9333 | 100 | 0.285 | Contact Map | 0.544 |
| 3cqjA | 2 | 0.9298 | 100 | 0.285 | Contact Map | 0.677 |
| 1k77A | 1 | 0.8667 | 100 | 0.289 | Contact Map | 0.698 |
| 3vylA | 8 | 0.8912 | 100 | 0.291 | Contact Map | 0.716 |
| 1i60A | 1 | 0.9158 | 100 | 0.292 | Contact Map | 0.665 |
Sequence Conservation (Image Generated using WebLogo v3)