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OPENSEQ.org

HEM4 - YQAB
UniProt: P09126 - P77475
Length: 434
Sequences: 266
Seq/Len: 0.62
I_Prob: 0.00

HEM4 - Uroporphyrinogen-III synthase
Paralog alert: 0.13 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: HEM4
YQAB - Fructose-1-phosphate phosphatase YqaB
Paralog alert: 0.91 [within 20: 0.23] - ratio of genomes with paralogs
Cluster includes: GPH PGMB YFBT YIEH YIGB YIHX YJJG YNIC YQAB YRFG
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
193_L 42_A 1.51 0.00
153_T 6_A 1.46 0.00
22_L 101_G 1.46 0.00
182_V 91_P 1.37 0.00
128_R 156_G 1.24 0.00
106_P 37_Q 1.12 0.00
66_F 165_F 1.11 0.00
17_S 81_S 1.11 0.00
184_V 45_A 1.09 0.00
133_R 124_G 1.08 0.00
116_L 27_W 1.07 0.00
187_G 79_V 1.04 0.00
9_S 39_D 1.02 0.00
32_I 102_R 1.01 0.00
20_R 121_A 1.00 0.00
186_S 10_F 0.98 0.00
142_G 79_V 0.97 0.00
75_D 47_N 0.96 0.00
185_T 37_Q 0.96 0.00
14_E 145_P 0.96 0.00
113_E 110_G 0.96 0.00
213_V 120_L 0.96 0.00
58_A 5_Y 0.95 0.00
17_S 145_P 0.94 0.00
100_G 89_P 0.93 0.00
214_V 148_F 0.92 0.00
206_L 84_L 0.92 0.00
189_M 95_V 0.91 0.00
131_I 172_I 0.90 0.00
206_L 56_Q 0.90 0.00
214_V 123_L 0.90 0.00
3_I 123_L 0.89 0.00
236_A 14_G 0.89 0.00
97_T 153_Q 0.89 0.00
228_Q 132_V 0.89 0.00
50_L 29_E 0.89 0.00
106_P 165_F 0.89 0.00
192_Q 176_R 0.89 0.00
146_T 73_R 0.89 0.00
3_I 96_V 0.89 0.00
106_P 155_M 0.88 0.00
14_E 157_V 0.88 0.00
70_Q 165_F 0.88 0.00
12_G 176_R 0.88 0.00
193_L 7_G 0.88 0.00
58_A 180_M 0.88 0.00
41_P 126_R 0.87 0.00
90_T 176_R 0.87 0.00
245_L 124_G 0.86 0.00
243_R 80_R 0.86 0.00
195_S 77_E 0.86 0.00
146_T 77_E 0.86 0.00
235_N 78_A 0.86 0.00
64_V 4_R 0.86 0.00
95_L 178_A 0.86 0.00
81_L 178_A 0.85 0.00
179_V 86_S 0.85 0.00
157_C 113_S 0.85 0.00
141_I 8_L 0.85 0.00
107_Q 6_A 0.85 0.00
86_A 165_F 0.85 0.00
131_I 119_L 0.85 0.00
117_Q 86_S 0.84 0.00
36_P 65_D 0.84 0.00
57_F 61_L 0.84 0.00
100_G 138_V 0.84 0.00
144_T 100_H 0.84 0.00
195_S 156_G 0.84 0.00
129_A 156_G 0.83 0.00
32_I 132_V 0.83 0.00
233_A 79_V 0.83 0.00
235_N 85_D 0.83 0.00
83_D 70_A 0.83 0.00
36_P 177_A 0.83 0.00
93_L 90_L 0.83 0.00
128_R 161_Q 0.82 0.00
113_E 15_T 0.82 0.00
142_G 78_A 0.82 0.00
124_I 160_T 0.82 0.00
156_E 109_T 0.82 0.00
221_L 46_L 0.82 0.00
22_L 39_D 0.82 0.00
58_A 178_A 0.82 0.00
223_R 94_D 0.82 0.00
242_L 21_P 0.82 0.00
147_A 61_L 0.81 0.00
232_V 86_S 0.81 0.00
183_V 19_T 0.81 0.00
45_D 173_Q 0.81 0.00
43_L 185_V 0.81 0.00
141_I 92_L 0.81 0.00
227_W 155_M 0.81 0.00
239_D 152_A 0.81 0.00
5_V 94_D 0.80 0.00
32_I 103_R 0.80 0.00
175_Q 29_E 0.80 0.00
138_R 125_L 0.80 0.00
216_E 156_G 0.80 0.00
215_S 83_L 0.80 0.00
175_Q 126_R 0.80 0.00
50_L 120_L 0.79 0.00
77_K 97_K 0.79 0.00
84_Y 109_T 0.79 0.00
218_L 107_V 0.79 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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