| UniProt: | P09126 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10430 | ||
| Length: | 246 (245) | ||
| Sequences: | 2084 | ||
| Seq/Len: | 8.51 |
| HEM4
Paralog alert: 0.13 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 19_L | 24_Q | 4.544 | 1.00 | |
| 53_S | 153_T | 3.795 | 1.00 | |
| 187_G | 221_L | 3.583 | 1.00 | |
| 213_V | 219_A | 3.54 | 1.00 | |
| 219_A | 232_V | 2.78 | 1.00 | |
| 135_N | 159_Q | 2.767 | 1.00 | |
| 55_L | 85_F | 2.758 | 1.00 | |
| 181_M | 212_L | 2.289 | 1.00 | |
| 133_R | 154_F | 2.251 | 1.00 | |
| 86_A | 92_A | 2.178 | 1.00 | |
| 128_R | 151_E | 2.159 | 1.00 | |
| 2_S | 25_V | 2.139 | 1.00 | |
| 54_D | 127_K | 2.059 | 1.00 | |
| 35_S | 159_Q | 2.027 | 1.00 | |
| 58_A | 64_V | 2.025 | 1.00 | |
| 53_S | 130_L | 1.997 | 1.00 | |
| 84_Y | 100_G | 1.932 | 1.00 | |
| 213_V | 232_V | 1.923 | 1.00 | |
| 144_T | 147_A | 1.919 | 1.00 | |
| 220_K | 223_R | 1.918 | 1.00 | |
| 5_V | 16_V | 1.896 | 1.00 | |
| 18_R | 22_L | 1.837 | 1.00 | |
| 44_A | 70_Q | 1.793 | 1.00 | |
| 214_V | 218_L | 1.765 | 1.00 | |
| 16_V | 28_H | 1.76 | 1.00 | |
| 213_V | 222_A | 1.741 | 1.00 | |
| 233_A | 240_A | 1.739 | 1.00 | |
| 236_A | 240_A | 1.736 | 1.00 | |
| 163_I | 192_Q | 1.728 | 1.00 | |
| 191_Q | 221_L | 1.726 | 1.00 | |
| 113_E | 138_R | 1.709 | 1.00 | |
| 35_S | 161_C | 1.694 | 1.00 | |
| 133_R | 137_G | 1.688 | 1.00 | |
| 112_S | 141_I | 1.688 | 1.00 | |
| 215_S | 218_L | 1.685 | 1.00 | |
| 219_A | 223_R | 1.679 | 1.00 | |
| 11_A | 62_H | 1.664 | 1.00 | |
| 116_L | 144_T | 1.662 | 1.00 | |
| 65_A | 94_A | 1.611 | 1.00 | |
| 211_L | 227_W | 1.607 | 1.00 | |
| 85_F | 115_L | 1.574 | 1.00 | |
| 184_V | 190_L | 1.563 | 1.00 | |
| 58_A | 67_A | 1.555 | 1.00 | |
| 19_L | 26_A | 1.543 | 1.00 | |
| 111_I | 114_V | 1.54 | 1.00 | |
| 135_N | 156_E | 1.536 | 1.00 | |
| 212_L | 241_L | 1.536 | 1.00 | |
| 184_V | 193_L | 1.521 | 1.00 | |
| 190_L | 222_A | 1.514 | 1.00 | |
| 160_R | 188_E | 1.507 | 1.00 | |
| 231_K | 244_A | 1.48 | 1.00 | |
| 34_F | 62_H | 1.454 | 0.99 | |
| 181_M | 245_L | 1.452 | 0.99 | |
| 16_V | 26_A | 1.448 | 0.99 | |
| 4_L | 179_V | 1.427 | 0.99 | |
| 185_T | 189_M | 1.402 | 0.99 | |
| 18_R | 239_D | 1.398 | 0.99 | |
| 34_F | 160_R | 1.394 | 0.99 | |
| 86_A | 95_L | 1.391 | 0.99 | |
| 55_L | 129_A | 1.379 | 0.99 | |
| 5_V | 12_G | 1.355 | 0.99 | |
| 187_G | 217_R | 1.336 | 0.99 | |
| 66_F | 157_C | 1.334 | 0.99 | |
| 106_P | 110_E | 1.334 | 0.99 | |
| 33_E | 163_I | 1.33 | 0.99 | |
| 184_V | 211_L | 1.319 | 0.99 | |
| 36_P | 66_F | 1.301 | 0.98 | |
| 33_E | 161_C | 1.297 | 0.98 | |
| 222_A | 227_W | 1.293 | 0.98 | |
| 212_L | 231_K | 1.284 | 0.98 | |
| 68_Q | 98_V | 1.279 | 0.98 | |
| 54_D | 128_R | 1.259 | 0.98 | |
| 49_A | 52_E | 1.257 | 0.98 | |
| 64_V | 91_T | 1.251 | 0.98 | |
| 5_V | 26_A | 1.247 | 0.98 | |
| 94_A | 97_T | 1.246 | 0.98 | |
| 96_H | 101_Q | 1.245 | 0.98 | |
| 142_G | 154_F | 1.245 | 0.98 | |
| 119_P | 148_R | 1.231 | 0.98 | |
| 137_G | 160_R | 1.231 | 0.98 | |
| 194_W | 225_L | 1.229 | 0.98 | |
| 32_I | 160_R | 1.225 | 0.98 | |
| 221_L | 225_L | 1.22 | 0.97 | |
| 220_K | 224_E | 1.212 | 0.97 | |
| 210_R | 231_K | 1.196 | 0.97 | |
| 58_A | 132_L | 1.185 | 0.97 | |
| 7_R | 189_M | 1.182 | 0.97 | |
| 128_R | 153_T | 1.177 | 0.97 | |
| 139_E | 143_D | 1.168 | 0.96 | |
| 124_I | 150_A | 1.167 | 0.96 | |
| 211_L | 222_A | 1.166 | 0.96 | |
| 27_W | 179_V | 1.162 | 0.96 | |
| 136_G | 160_R | 1.159 | 0.96 | |
| 96_H | 102_K | 1.154 | 0.96 | |
| 83_D | 103_I | 1.152 | 0.96 | |
| 112_S | 116_L | 1.131 | 0.96 | |
| 221_L | 224_E | 1.119 | 0.95 | |
| 136_G | 156_E | 1.112 | 0.95 | |
| 18_R | 21_T | 1.11 | 0.95 | |
| 56_L | 132_L | 1.106 | 0.95 | |
| 187_G | 218_L | 1.1 | 0.95 | |
| 9_S | 12_G | 1.09 | 0.94 | |
| 222_A | 229_D | 1.087 | 0.94 | |
| 143_D | 146_T | 1.082 | 0.94 | |
| 57_F | 145_L | 1.077 | 0.94 | |
| 233_A | 244_A | 1.065 | 0.93 | |
| 188_E | 215_S | 1.061 | 0.93 | |
| 112_S | 140_L | 1.057 | 0.93 | |
| 45_D | 48_A | 1.056 | 0.93 | |
| 174_W | 205_W | 1.052 | 0.93 | |
| 145_L | 150_A | 1.047 | 0.92 | |
| 183_V | 212_L | 1.043 | 0.92 | |
| 216_E | 236_A | 1.036 | 0.92 | |
| 136_G | 188_E | 1.032 | 0.92 | |
| 20_R | 26_A | 1.029 | 0.92 | |
| 62_H | 66_F | 1.017 | 0.91 | |
| 87_I | 115_L | 1.015 | 0.91 | |
| 5_V | 19_L | 1.013 | 0.91 | |
| 233_A | 236_A | 1.006 | 0.90 | |
| 2_S | 27_W | 1.004 | 0.90 | |
| 184_V | 189_M | 1.001 | 0.90 | |
| 61_Q | 90_T | 1 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3re1A | 2 | 0.9837 | 100 | 0.113 | Contact Map | 0.779 |
| 4es6A | 1 | 0.9837 | 100 | 0.117 | Contact Map | 0.76 |
| 3mw8A | 1 | 0.9634 | 100 | 0.134 | Contact Map | 0.763 |
| 1jr2A | 2 | 0.9837 | 100 | 0.141 | Contact Map | 0.733 |
| 1wcwA | 1 | 0.9675 | 100 | 0.141 | Contact Map | 0.791 |
| 3d8tA | 2 | 0.9675 | 100 | 0.143 | Contact Map | 0.813 |
| 3p9zA | 1 | 0.874 | 100 | 0.239 | Contact Map | 0.778 |
| 3clkA | 2 | 0.9187 | 94 | 0.891 | Contact Map | 0.306 |
| 3qk7A | 3 | 0.9187 | 93.9 | 0.892 | Contact Map | 0.373 |
| 2fepA | 1 | 0.9228 | 93.8 | 0.892 | Contact Map | 0.336 |
Sequence Conservation (Image Generated using WebLogo v3)