May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

YQAB - Fructose-1-phosphate phosphatase YqaB
UniProt: P77475 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13530
Length: 188 (184)
Sequences: 12783
Seq/Len: 69.47

YQAB
Paralog alert: 0.91 [within 20: 0.23] - ratio of genomes with paralogs
Cluster includes: GPH PGMB YFBT YIEH YIGB YIHX YJJG YNIC YQAB YRFG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
6_A 161_Q 4.018 1.00
166_E 171_G 3.436 1.00
175_A 182_A 2.83 1.00
150_L 154_R 2.749 1.00
121_A 126_R 2.712 1.00
140_H 144_A 2.562 1.00
113_S 117_E 2.401 1.00
7_G 157_V 2.371 1.00
97_K 128_Y 2.348 1.00
152_A 162_C 2.278 1.00
104_P 130_D 2.239 1.00
150_L 153_Q 2.225 1.00
33_H 74_E 2.222 1.00
172_I 182_A 2.177 1.00
5_Y 181_D 2.173 1.00
93_V 97_K 2.163 1.00
109_T 116_A 2.148 1.00
113_S 137_H 2.086 1.00
173_Q 177_A 2.005 1.00
108_G 147_T 1.959 1.00
100_H 130_D 1.954 1.00
163_V 183_V 1.926 1.00
10_F 105_M 1.924 1.00
106_A 131_A 1.909 1.00
152_A 180_M 1.908 1.00
140_H 146_D 1.869 1.00
158_Q 161_Q 1.832 1.00
131_A 154_R 1.801 1.00
39_D 42_A 1.676 1.00
9_I 108_G 1.67 1.00
8_L 103_R 1.651 1.00
100_H 128_Y 1.646 1.00
164_V 175_A 1.616 1.00
29_E 78_A 1.58 1.00
105_M 129_F 1.562 1.00
152_A 159_P 1.558 1.00
7_G 155_M 1.522 1.00
8_L 165_F 1.476 1.00
157_V 162_C 1.452 1.00
9_I 151_C 1.436 1.00
8_L 99_W 1.419 1.00
98_S 102_R 1.4 0.99
91_P 94_D 1.373 0.99
15_T 165_F 1.368 0.99
106_A 155_M 1.363 0.99
53_R 56_Q 1.355 0.99
12_M 17_L 1.352 0.99
169_D 173_Q 1.345 0.99
67_D 70_A 1.31 0.99
117_E 126_R 1.305 0.99
16_I 92_L 1.293 0.99
9_I 164_V 1.286 0.99
7_G 162_C 1.277 0.99
12_M 116_A 1.268 0.99
162_C 180_M 1.252 0.99
133_V 154_R 1.245 0.98
78_A 81_S 1.24 0.98
9_I 162_C 1.239 0.98
145_P 149_L 1.224 0.98
29_E 33_H 1.21 0.98
133_V 151_C 1.189 0.98
176_R 182_A 1.181 0.98
73_R 77_E 1.181 0.98
148_F 164_V 1.178 0.98
116_A 134_A 1.163 0.97
98_S 101_G 1.161 0.97
34_Y 74_E 1.142 0.97
12_M 107_V 1.14 0.97
172_I 184_D 1.132 0.97
107_V 129_F 1.123 0.97
148_F 166_E 1.108 0.96
88_E 125_L 1.108 0.96
100_H 105_M 1.106 0.96
146_D 150_L 1.098 0.96
25_K 29_E 1.091 0.96
94_D 97_K 1.087 0.96
5_Y 163_V 1.081 0.95
13_D 19_T 1.081 0.95
148_F 180_M 1.072 0.95
174_A 178_A 1.057 0.95
75_K 79_V 1.056 0.95
7_G 104_P 1.053 0.95
74_E 78_A 1.053 0.95
97_K 101_G 1.041 0.94
109_T 134_A 1.041 0.94
117_E 121_A 1.035 0.94
30_V 34_Y 1.022 0.93
25_K 28_R 1.015 0.93
74_E 77_E 1.013 0.93
108_G 151_C 1.012 0.93
164_V 180_M 1.007 0.93
165_F 183_V 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3l5kA111000.21Contact Map0.794
4eekA10.99471000.221Contact Map0.794
3s6jA611000.221Contact Map0.7
3iruA211000.23Contact Map0.683
4g9bA10.98941000.231Contact Map0.788
1te2A211000.233Contact Map0.881
1swvA211000.235Contact Map0.801
3nasA20.97341000.235Contact Map0.78
3qxgA20.98941000.237Contact Map0.832
3ed5A10.97871000.24Contact Map0.799

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0737 seconds.