| UniProt: | P32662 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11871 | ||
| Length: | 252 (231) | ||
| Sequences: | 9142 | ||
| Seq/Len: | 39.58 |
| GPH
Paralog alert: 0.89 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: GPH PGMB YFBT YIEH YIGB YIHX YJJG YNIC YQAB YRFG |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 8_R | 186_Q | 4.212 | 1.00 | |
| 200_A | 207_S | 3.265 | 1.00 | |
| 175_L | 179_R | 3.056 | 1.00 | |
| 146_E | 151_A | 2.929 | 1.00 | |
| 191_G | 196_D | 2.738 | 1.00 | |
| 201_K | 226_D | 2.719 | 1.00 | |
| 138_T | 142_A | 2.68 | 1.00 | |
| 165_N | 169_H | 2.647 | 1.00 | |
| 9_G | 182_I | 2.64 | 1.00 | |
| 121_G | 153_Y | 2.578 | 1.00 | |
| 177_A | 187_M | 2.53 | 1.00 | |
| 134_T | 141_V | 2.413 | 1.00 | |
| 129_P | 155_S | 2.396 | 1.00 | |
| 175_L | 178_E | 2.341 | 1.00 | |
| 35_A | 97_L | 2.306 | 1.00 | |
| 117_A | 121_G | 2.271 | 1.00 | |
| 230_Q | 234_D | 2.226 | 1.00 | |
| 124_Q | 155_S | 2.206 | 1.00 | |
| 7_I | 206_P | 2.146 | 1.00 | |
| 197_I | 207_S | 2.131 | 1.00 | |
| 138_T | 162_D | 2.118 | 1.00 | |
| 116_V | 232_I | 2.097 | 1.00 | |
| 133_V | 172_P | 2.068 | 1.00 | |
| 198_Q | 202_A | 2.066 | 1.00 | |
| 31_M | 101_Y | 1.99 | 1.00 | |
| 188_L | 208_V | 1.956 | 1.00 | |
| 177_A | 205_C | 1.947 | 1.00 | |
| 206_P | 226_D | 1.911 | 1.00 | |
| 11_A | 133_V | 1.906 | 1.00 | |
| 10_V | 190_V | 1.905 | 1.00 | |
| 183_A | 186_Q | 1.806 | 1.00 | |
| 130_L | 154_F | 1.787 | 1.00 | |
| 12_F | 130_L | 1.76 | 1.00 | |
| 10_V | 123_L | 1.721 | 1.00 | |
| 165_N | 171_D | 1.681 | 1.00 | |
| 124_Q | 153_Y | 1.68 | 1.00 | |
| 182_I | 187_M | 1.678 | 1.00 | |
| 131_G | 156_V | 1.657 | 1.00 | |
| 10_V | 128_L | 1.633 | 1.00 | |
| 211_T | 230_Q | 1.624 | 1.00 | |
| 189_F | 200_A | 1.602 | 1.00 | |
| 122_A | 126_K | 1.588 | 1.00 | |
| 9_G | 180_M | 1.568 | 1.00 | |
| 177_A | 184_P | 1.545 | 1.00 | |
| 18_L | 116_V | 1.507 | 1.00 | |
| 231_S | 234_D | 1.503 | 1.00 | |
| 156_V | 179_R | 1.468 | 1.00 | |
| 208_V | 229_Y | 1.455 | 1.00 | |
| 131_G | 180_M | 1.446 | 1.00 | |
| 42_G | 45_R | 1.425 | 1.00 | |
| 56_V | 59_E | 1.423 | 1.00 | |
| 122_A | 236_L | 1.418 | 1.00 | |
| 112_L | 150_I | 1.396 | 0.99 | |
| 11_A | 176_V | 1.392 | 0.99 | |
| 122_A | 125_A | 1.386 | 0.99 | |
| 187_M | 205_C | 1.382 | 0.99 | |
| 121_G | 125_A | 1.373 | 0.99 | |
| 14_L | 141_V | 1.355 | 0.99 | |
| 173_L | 205_C | 1.353 | 0.99 | |
| 31_M | 35_A | 1.338 | 0.99 | |
| 17_T | 190_V | 1.33 | 0.99 | |
| 36_L | 97_L | 1.309 | 0.99 | |
| 35_A | 101_Y | 1.299 | 0.99 | |
| 118_D | 233_N | 1.284 | 0.99 | |
| 208_V | 227_V | 1.282 | 0.99 | |
| 158_I | 176_V | 1.264 | 0.99 | |
| 217_G | 221_D | 1.253 | 0.99 | |
| 14_L | 19_V | 1.247 | 0.99 | |
| 197_I | 225_P | 1.244 | 0.98 | |
| 142_A | 151_A | 1.24 | 0.98 | |
| 119_T | 232_I | 1.235 | 0.98 | |
| 173_L | 189_F | 1.217 | 0.98 | |
| 119_T | 236_L | 1.215 | 0.98 | |
| 115_H | 118_D | 1.214 | 0.98 | |
| 141_V | 159_G | 1.211 | 0.98 | |
| 197_I | 209_G | 1.205 | 0.98 | |
| 229_Y | 235_L | 1.204 | 0.98 | |
| 158_I | 179_R | 1.2 | 0.98 | |
| 227_V | 238_A | 1.189 | 0.98 | |
| 123_L | 128_L | 1.18 | 0.98 | |
| 133_V | 176_V | 1.172 | 0.98 | |
| 218_E | 222_L | 1.167 | 0.97 | |
| 164_Q | 171_D | 1.153 | 0.97 | |
| 15_D | 21_S | 1.148 | 0.97 | |
| 134_T | 159_G | 1.146 | 0.97 | |
| 32_A | 36_L | 1.144 | 0.97 | |
| 142_A | 146_E | 1.142 | 0.97 | |
| 173_L | 191_G | 1.134 | 0.97 | |
| 195_N | 198_Q | 1.122 | 0.97 | |
| 34_Y | 40_V | 1.12 | 0.96 | |
| 113_F | 212_Y | 1.114 | 0.96 | |
| 112_L | 117_A | 1.105 | 0.96 | |
| 120_L | 153_Y | 1.099 | 0.96 | |
| 101_Y | 104_E | 1.094 | 0.96 | |
| 173_L | 199_A | 1.092 | 0.96 | |
| 194_R | 198_Q | 1.077 | 0.95 | |
| 190_V | 208_V | 1.068 | 0.95 | |
| 11_A | 187_M | 1.068 | 0.95 | |
| 174_L | 184_P | 1.058 | 0.95 | |
| 27_A | 105_V | 1.053 | 0.95 | |
| 98_F | 102_Y | 1.047 | 0.94 | |
| 27_A | 109_G | 1.043 | 0.94 | |
| 211_T | 228_I | 1.043 | 0.94 | |
| 105_V | 108_E | 1.042 | 0.94 | |
| 189_F | 205_C | 1.029 | 0.94 | |
| 143_P | 147_A | 1.028 | 0.94 | |
| 27_A | 31_M | 1.025 | 0.93 | |
| 115_H | 119_T | 1.023 | 0.93 | |
| 149_D | 152_K | 1.019 | 0.93 | |
| 101_Y | 105_V | 1.016 | 0.93 | |
| 115_H | 231_S | 1.015 | 0.93 | |
| 97_L | 100_R | 1.015 | 0.93 | |
| 9_G | 187_M | 1.009 | 0.93 | |
| 171_D | 175_L | 1.004 | 0.93 | |
| 30_D | 34_Y | 1.003 | 0.93 | |
| 138_T | 159_G | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1swvA | 2 | 0.9563 | 100 | 0.353 | Contact Map | 0.795 |
| 4eekA | 1 | 0.9087 | 100 | 0.355 | Contact Map | 0.749 |
| 3d6jA | 1 | 0.8929 | 100 | 0.359 | Contact Map | 0.84 |
| 3iruA | 2 | 0.9683 | 100 | 0.36 | Contact Map | 0.68 |
| 1te2A | 2 | 0.8849 | 100 | 0.361 | Contact Map | 0.846 |
| 3s6jA | 6 | 0.9206 | 100 | 0.363 | Contact Map | 0.706 |
| 3mc1A | 2 | 0.8968 | 100 | 0.37 | Contact Map | 0.794 |
| 4ex6A | 1 | 0.8849 | 100 | 0.37 | Contact Map | 0.723 |
| 3sd7A | 1 | 0.8532 | 100 | 0.37 | Contact Map | 0.781 |
| 2ah5A | 1 | 0.8333 | 100 | 0.378 | Contact Map | 0.812 |
Sequence Conservation (Image Generated using WebLogo v3)