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OPENSEQ.org

YFBT - Sugar phosphatase YfbT
UniProt: P77625 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14104
Length: 216 (204)
Sequences: 11366
Seq/Len: 55.72

YFBT
Paralog alert: 0.90 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: GPH PGMB YFBT YIEH YIGB YIHX YJJG YNIC YQAB YRFG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
4_K 157_E 4.218 1.00
162_E 167_G 3.134 1.00
146_L 150_L 3.076 1.00
171_G 178_V 3.064 1.00
136_R 140_E 2.706 1.00
172_L 194_D 2.588 1.00
5_G 153_L 2.533 1.00
106_T 113_A 2.522 1.00
148_A 158_C 2.487 1.00
110_M 114_R 2.465 1.00
146_L 149_Q 2.452 1.00
89_I 93_S 2.218 1.00
96_N 126_E 2.173 1.00
101_P 126_E 2.172 1.00
168_V 178_V 2.164 1.00
169_L 173_A 2.139 1.00
198_H 202_Q 2.11 1.00
93_S 124_A 2.088 1.00
105_V 143_A 2.064 1.00
148_A 176_C 2.031 1.00
110_M 133_R 2.022 1.00
159_V 179_I 1.979 1.00
8_F 102_W 1.928 1.00
136_R 142_D 1.904 1.00
3_C 177_H 1.903 1.00
7_L 105_V 1.872 1.00
154_A 157_E 1.823 1.00
103_A 127_V 1.783 1.00
177_H 194_D 1.769 1.00
88_A 200_L 1.743 1.00
160_V 171_G 1.742 1.00
127_V 150_L 1.692 1.00
153_L 158_C 1.675 1.00
6_F 100_I 1.665 1.00
148_A 155_P 1.623 1.00
182_N 198_H 1.601 1.00
5_G 151_L 1.6 1.00
94_H 98_A 1.589 1.00
6_F 161_V 1.581 1.00
50_T 53_R 1.58 1.00
102_W 125_P 1.569 1.00
6_F 95_L 1.507 1.00
7_L 147_G 1.505 1.00
13_T 161_V 1.468 1.00
31_R 67_E 1.417 1.00
96_N 124_A 1.41 1.00
103_A 151_L 1.392 0.99
60_S 63_D 1.386 0.99
14_L 88_A 1.359 0.99
199_S 202_Q 1.353 0.99
10_L 15_V 1.35 0.99
27_N 31_R 1.349 0.99
179_I 197_L 1.343 0.99
165_P 169_L 1.337 0.99
158_C 176_C 1.323 0.99
87_G 90_A 1.319 0.99
11_D 17_S 1.264 0.99
144_Y 160_V 1.25 0.99
77_T 80_E 1.231 0.98
10_L 113_A 1.22 0.98
93_S 97_K 1.218 0.98
129_V 150_L 1.197 0.98
142_D 146_L 1.187 0.98
144_Y 162_E 1.183 0.98
144_Y 176_C 1.178 0.98
90_A 201_E 1.177 0.98
105_V 147_G 1.177 0.98
5_G 158_C 1.177 0.98
129_V 147_G 1.175 0.98
28_W 32_H 1.174 0.98
94_H 204_T 1.174 0.98
7_L 160_V 1.159 0.97
135_K 142_D 1.157 0.97
7_L 158_C 1.155 0.97
179_I 195_L 1.151 0.97
91_L 200_L 1.14 0.97
94_H 97_K 1.135 0.97
160_V 176_C 1.13 0.97
168_V 180_A 1.124 0.97
95_L 100_I 1.12 0.96
90_A 93_S 1.116 0.96
106_T 130_T 1.102 0.96
141_P 145_L 1.094 0.96
114_R 118_K 1.092 0.96
23_R 27_N 1.087 0.96
166_A 169_L 1.086 0.96
161_V 179_I 1.068 0.95
5_G 101_P 1.062 0.95
96_N 102_W 1.057 0.95
84_A 89_I 1.05 0.94
3_C 159_V 1.048 0.94
84_A 122_L 1.045 0.94
23_R 81_G 1.045 0.94
10_L 104_I 1.039 0.94
113_A 130_T 1.038 0.94
197_L 203_I 1.031 0.94
145_L 155_P 1.029 0.94
110_M 130_T 1.028 0.94
31_R 70_R 1.016 0.93
23_R 26_S 1.014 0.93
144_Y 170_S 1.01 0.93
144_Y 167_G 1.007 0.93
49_I 53_R 1.005 0.93
159_V 177_H 1.005 0.93
172_L 178_V 1.004 0.93
26_S 30_R 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4eekA10.98151000.294Contact Map0.77
2hdoA10.94911000.296Contact Map0.836
4g9bA10.96761000.307Contact Map0.788
1te2A20.98151000.307Contact Map0.868
3l5kA10.97691000.311Contact Map0.796
3iruA211000.311Contact Map0.726
2hi0A20.97221000.315Contact Map0.795
3d6jA10.99071000.317Contact Map0.854
3s6jA611000.317Contact Map0.761
1swvA211000.317Contact Map0.848

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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