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TAUC - Taurine transport system permease protein TauC
UniProt: Q47539 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13301
Length: 275 (244)
Sequences: 4655
Seq/Len: 19.08

TAUC
Paralog alert: 0.65 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
39_W 43_T 4.318 1.00
39_W 56_Q 3.106 1.00
112_R 166_K 2.985 1.00
176_A 190_V 2.91 1.00
62_L 244_A 2.866 1.00
182_S 185_Q 2.634 1.00
134_M 147_L 2.627 1.00
184_A 188_W 2.542 1.00
93_A 150_Y 2.498 1.00
86_R 142_E 2.399 1.00
81_A 85_T 2.384 1.00
69_Q 75_T 2.329 1.00
83_S 214_L 2.281 1.00
85_T 89_L 2.269 1.00
164_G 198_E 2.24 1.00
238_A 241_V 2.212 1.00
138_F 147_L 2.107 1.00
230_V 245_G 2.075 1.00
59_L 63_L 2.005 1.00
95_V 203_L 1.948 1.00
94_A 153_I 1.94 1.00
102_G 106_G 1.94 1.00
79_H 229_M 1.913 1.00
97_F 154_F 1.91 1.00
97_F 150_Y 1.884 1.00
41_V 46_L 1.863 1.00
161_A 199_I 1.806 1.00
109_P 112_R 1.806 1.00
154_F 158_A 1.788 1.00
105_M 158_A 1.758 1.00
97_F 100_P 1.756 1.00
157_V 206_G 1.745 1.00
266_R 269_P 1.732 1.00
94_A 150_Y 1.711 1.00
63_L 68_P 1.686 1.00
89_L 146_I 1.669 1.00
195_A 199_I 1.652 1.00
233_A 241_V 1.645 1.00
176_A 181_A 1.637 1.00
183_R 186_V 1.624 1.00
66_A 77_W 1.62 1.00
259_G 263_L 1.61 1.00
102_G 165_V 1.602 1.00
57_Q 60_E 1.589 1.00
262_A 266_R 1.579 1.00
262_A 265_R 1.562 1.00
60_E 64_T 1.557 1.00
109_P 113_G 1.553 1.00
185_Q 189_F 1.544 1.00
143_T 147_L 1.53 1.00
165_V 191_I 1.499 1.00
56_Q 60_E 1.475 1.00
111_V 115_L 1.454 1.00
168_V 194_G 1.43 1.00
173_I 186_V 1.428 1.00
229_M 245_G 1.417 1.00
258_L 262_A 1.409 1.00
42_A 54_P 1.408 1.00
40_T 44_L 1.4 0.99
98_G 157_V 1.354 0.99
98_G 158_A 1.347 0.99
54_P 57_Q 1.344 0.99
204_R 264_Q 1.327 0.99
175_A 179_L 1.322 0.99
96_L 100_P 1.319 0.99
108_S 111_V 1.319 0.99
105_M 162_L 1.313 0.99
61_K 238_A 1.311 0.99
82_A 86_R 1.302 0.99
36_T 40_T 1.298 0.99
82_A 224_R 1.281 0.99
134_M 144_S 1.264 0.99
91_L 203_L 1.261 0.99
101_V 154_F 1.252 0.99
164_G 202_G 1.234 0.98
106_G 165_V 1.234 0.98
134_M 138_F 1.232 0.98
174_R 177_Q 1.223 0.98
43_T 56_Q 1.215 0.98
171_V 174_R 1.215 0.98
63_L 66_A 1.214 0.98
231_Q 234_G 1.214 0.98
80_L 252_I 1.211 0.98
134_M 151_L 1.195 0.98
133_L 137_W 1.184 0.98
49_P 57_Q 1.184 0.98
105_M 111_V 1.184 0.98
91_L 95_V 1.177 0.98
177_Q 186_V 1.164 0.97
61_K 64_T 1.163 0.97
77_W 81_A 1.16 0.97
185_Q 188_W 1.155 0.97
255_L 259_G 1.144 0.97
39_W 54_P 1.138 0.97
90_A 149_I 1.136 0.97
152_A 213_T 1.135 0.97
94_A 157_V 1.132 0.97
175_A 180_G 1.129 0.97
78_Q 224_R 1.124 0.97
99_I 199_I 1.123 0.97
101_V 158_A 1.121 0.97
128_L 216_A 1.12 0.96
107_L 183_R 1.114 0.96
84_L 252_I 1.113 0.96
80_L 226_L 1.111 0.96
84_L 88_M 1.111 0.96
120_E 123_R 1.102 0.96
95_V 99_I 1.1 0.96
107_L 110_T 1.097 0.96
61_K 240_D 1.095 0.96
263_L 267_L 1.094 0.96
88_M 92_F 1.093 0.96
215_V 249_I 1.092 0.96
181_A 185_Q 1.085 0.96
62_L 248_V 1.08 0.95
87_I 214_L 1.076 0.95
169_Q 172_R 1.055 0.95
160_S 201_T 1.055 0.95
104_A 111_V 1.055 0.95
98_G 161_A 1.054 0.95
202_G 206_G 1.04 0.94
258_L 261_R 1.036 0.94
226_L 245_G 1.034 0.94
181_A 186_V 1.025 0.93
207_L 256_L 1.021 0.93
170_Q 174_R 1.013 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3d31C20.9699.90.608Contact Map0.585
2onkC40.956499.90.627Contact Map0.64
3rlfF10.974599.90.635Contact Map0.661
3tuiA40.734599.90.647Contact Map0.752
3rlfG10.956499.80.68Contact Map0.542
2mc7A10.101850.965Contact Map0
3tdsE50.370930.969Contact Map0.378
3fymA10.16361.90.972Contact Map
2kv5A10.121.90.972Contact Map0.322
3arcK20.13091.80.972Contact Map0.291

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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