| UniProt: | P33359 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12009 | ||
| Length: | 243 (202) | ||
| Sequences: | 8131 | ||
| Seq/Len: | 40.25 |
| YEHW
Paralog alert: 0.86 [within 20: 0.44] - ratio of genomes with paralogs Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 156_G | 160_R | 3.485 | 1.00 | |
| 154_S | 157_Q | 3.217 | 1.00 | |
| 148_A | 162_V | 2.755 | 1.00 | |
| 63_F | 122_I | 2.547 | 1.00 | |
| 84_R | 138_G | 2.506 | 1.00 | |
| 149_K | 158_R | 2.477 | 1.00 | |
| 209_N | 212_Y | 2.224 | 1.00 | |
| 67_I | 122_I | 2.125 | 1.00 | |
| 51_L | 55_W | 2.116 | 1.00 | |
| 148_A | 153_M | 2.115 | 1.00 | |
| 136_G | 170_V | 2.07 | 1.00 | |
| 106_A | 119_I | 2.07 | 1.00 | |
| 110_I | 119_I | 2.004 | 1.00 | |
| 233_R | 237_A | 1.993 | 1.00 | |
| 65_V | 175_V | 1.992 | 1.00 | |
| 157_Q | 161_K | 1.916 | 1.00 | |
| 233_R | 236_Q | 1.859 | 1.00 | |
| 53_H | 56_L | 1.852 | 1.00 | |
| 72_G | 133_T | 1.846 | 1.00 | |
| 76_T | 137_L | 1.831 | 1.00 | |
| 201_I | 216_G | 1.814 | 1.00 | |
| 64_A | 125_G | 1.771 | 1.00 | |
| 49_L | 200_P | 1.762 | 1.00 | |
| 67_I | 70_G | 1.759 | 1.00 | |
| 55_W | 59_I | 1.744 | 1.00 | |
| 229_R | 233_R | 1.718 | 1.00 | |
| 72_G | 76_T | 1.702 | 1.00 | |
| 133_T | 171_I | 1.677 | 1.00 | |
| 61_S | 179_V | 1.674 | 1.00 | |
| 67_I | 126_V | 1.67 | 1.00 | |
| 145_T | 158_R | 1.653 | 1.00 | |
| 68_G | 130_L | 1.652 | 1.00 | |
| 66_I | 70_G | 1.646 | 1.00 | |
| 129_V | 178_S | 1.64 | 1.00 | |
| 81_A | 85_P | 1.638 | 1.00 | |
| 47_A | 51_L | 1.623 | 1.00 | |
| 155_R | 158_R | 1.594 | 1.00 | |
| 137_L | 163_E | 1.525 | 1.00 | |
| 230_L | 234_L | 1.503 | 1.00 | |
| 53_H | 186_A | 1.496 | 1.00 | |
| 49_L | 52_A | 1.491 | 1.00 | |
| 237_A | 240_Q | 1.491 | 1.00 | |
| 145_T | 163_E | 1.425 | 1.00 | |
| 115_Q | 119_I | 1.415 | 1.00 | |
| 59_I | 118_I | 1.405 | 0.99 | |
| 75_V | 130_L | 1.396 | 0.99 | |
| 183_I | 227_A | 1.385 | 0.99 | |
| 78_P | 83_F | 1.365 | 0.99 | |
| 68_G | 129_V | 1.359 | 0.99 | |
| 77_R | 155_R | 1.357 | 0.99 | |
| 136_G | 174_G | 1.346 | 0.99 | |
| 82_E | 86_L | 1.339 | 0.99 | |
| 64_A | 122_I | 1.337 | 0.99 | |
| 148_A | 158_R | 1.334 | 0.99 | |
| 126_V | 130_L | 1.333 | 0.99 | |
| 75_V | 134_L | 1.323 | 0.99 | |
| 204_G | 212_Y | 1.308 | 0.99 | |
| 52_A | 56_L | 1.296 | 0.99 | |
| 78_P | 81_A | 1.296 | 0.99 | |
| 81_A | 84_R | 1.263 | 0.99 | |
| 167_A | 171_I | 1.262 | 0.99 | |
| 84_R | 88_E | 1.259 | 0.99 | |
| 74_A | 83_F | 1.255 | 0.99 | |
| 72_G | 137_L | 1.252 | 0.99 | |
| 65_V | 69_T | 1.249 | 0.99 | |
| 200_P | 216_G | 1.246 | 0.98 | |
| 202_I | 205_L | 1.236 | 0.98 | |
| 71_A | 126_V | 1.223 | 0.98 | |
| 60_S | 121_L | 1.206 | 0.98 | |
| 114_L | 118_I | 1.177 | 0.98 | |
| 55_W | 114_L | 1.163 | 0.97 | |
| 49_L | 53_H | 1.155 | 0.97 | |
| 134_L | 138_G | 1.15 | 0.97 | |
| 78_P | 82_E | 1.14 | 0.97 | |
| 147_V | 152_G | 1.137 | 0.97 | |
| 77_R | 163_E | 1.134 | 0.97 | |
| 145_T | 149_K | 1.133 | 0.97 | |
| 50_A | 223_A | 1.125 | 0.97 | |
| 187_T | 220_V | 1.122 | 0.97 | |
| 140_I | 166_L | 1.12 | 0.96 | |
| 71_A | 130_L | 1.117 | 0.96 | |
| 147_V | 151_M | 1.117 | 0.96 | |
| 58_G | 62_L | 1.116 | 0.96 | |
| 117_A | 189_A | 1.115 | 0.96 | |
| 132_A | 174_G | 1.113 | 0.96 | |
| 202_I | 206_S | 1.113 | 0.96 | |
| 50_A | 197_L | 1.111 | 0.96 | |
| 176_R | 228_D | 1.102 | 0.96 | |
| 56_L | 114_L | 1.102 | 0.96 | |
| 84_R | 134_L | 1.101 | 0.96 | |
| 124_Y | 185_T | 1.094 | 0.96 | |
| 153_M | 157_Q | 1.088 | 0.96 | |
| 68_G | 72_G | 1.077 | 0.95 | |
| 176_R | 235_V | 1.076 | 0.95 | |
| 153_M | 158_R | 1.071 | 0.95 | |
| 61_S | 175_V | 1.069 | 0.95 | |
| 91_A | 130_L | 1.065 | 0.95 | |
| 74_A | 78_P | 1.06 | 0.95 | |
| 142_A | 146_E | 1.056 | 0.95 | |
| 53_H | 57_V | 1.054 | 0.95 | |
| 107_V | 111_G | 1.048 | 0.94 | |
| 69_T | 171_I | 1.04 | 0.94 | |
| 157_Q | 160_R | 1.04 | 0.94 | |
| 142_A | 149_K | 1.038 | 0.94 | |
| 52_A | 195_S | 1.034 | 0.94 | |
| 144_V | 147_V | 1.033 | 0.94 | |
| 106_A | 110_I | 1.03 | 0.94 | |
| 70_G | 74_A | 1.03 | 0.94 | |
| 172_L | 238_L | 1.028 | 0.94 | |
| 128_P | 181_I | 1.024 | 0.93 | |
| 225_I | 229_R | 1.023 | 0.93 | |
| 143_S | 146_E | 1.022 | 0.93 | |
| 146_E | 149_K | 1.017 | 0.93 | |
| 82_E | 85_P | 1.009 | 0.93 | |
| 179_V | 227_A | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3d31C | 2 | 0.9959 | 99.9 | 0.573 | Contact Map | 0.641 |
| 2onkC | 4 | 0.9959 | 99.9 | 0.574 | Contact Map | 0.674 |
| 3tuiA | 4 | 0.8395 | 99.9 | 0.587 | Contact Map | 0.8 |
| 3rlfF | 1 | 0.9835 | 99.9 | 0.615 | Contact Map | 0.688 |
| 3rlfG | 1 | 0.9959 | 99.8 | 0.648 | Contact Map | 0.576 |
| 4lz6A | 1 | 0.9342 | 10 | 0.954 | Contact Map | 0.331 |
| 3w4tA | 1 | 0.9218 | 8.2 | 0.956 | Contact Map | 0.27 |
| 3tdsE | 5 | 0.4033 | 7.5 | 0.957 | Contact Map | 0.412 |
| 3mktA | 2 | 0.9218 | 4.5 | 0.961 | Contact Map | 0.23 |
| 2kv5A | 1 | 0.1358 | 3.9 | 0.962 | Contact Map | 0.375 |
Sequence Conservation (Image Generated using WebLogo v3)