| UniProt: | P16683 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11283 | ||
| Length: | 259 (208) | ||
| Sequences: | 7064 | ||
| Seq/Len: | 33.96 |
| PHNE
Paralog alert: 0.88 [within 20: 0.35] - ratio of genomes with paralogs Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 174_N | 177_E | 3.718 | 1.00 | |
| 137_G | 209_V | 3.45 | 1.00 | |
| 82_L | 142_F | 3.217 | 1.00 | |
| 196_L | 251_S | 3.111 | 1.00 | |
| 229_Q | 232_Q | 2.932 | 1.00 | |
| 70_A | 74_Q | 2.597 | 1.00 | |
| 176_L | 180_L | 2.582 | 1.00 | |
| 168_I | 178_E | 2.565 | 1.00 | |
| 249_F | 253_R | 2.531 | 1.00 | |
| 76_A | 203_V | 2.5 | 1.00 | |
| 90_F | 146_T | 2.455 | 1.00 | |
| 117_I | 122_F | 2.425 | 1.00 | |
| 91_G | 153_L | 2.416 | 1.00 | |
| 253_R | 256_K | 2.285 | 1.00 | |
| 93_M | 107_V | 2.277 | 1.00 | |
| 102_W | 106_P | 2.202 | 1.00 | |
| 165_V | 178_E | 2.177 | 1.00 | |
| 164_P | 186_Q | 2.17 | 1.00 | |
| 66_L | 70_A | 2.15 | 1.00 | |
| 169_R | 178_E | 2.144 | 1.00 | |
| 111_M | 150_S | 2.094 | 1.00 | |
| 156_A | 191_L | 2.05 | 1.00 | |
| 90_F | 150_S | 1.999 | 1.00 | |
| 102_W | 105_Q | 1.995 | 1.00 | |
| 241_I | 245_S | 1.956 | 1.00 | |
| 221_L | 237_M | 1.911 | 1.00 | |
| 80_T | 199_F | 1.857 | 1.00 | |
| 69_M | 243_T | 1.849 | 1.00 | |
| 253_R | 257_H | 1.832 | 1.00 | |
| 86_L | 146_T | 1.819 | 1.00 | |
| 245_S | 249_F | 1.812 | 1.00 | |
| 78_W | 138_V | 1.743 | 1.00 | |
| 71_V | 74_Q | 1.713 | 1.00 | |
| 83_A | 145_T | 1.639 | 1.00 | |
| 85_V | 89_P | 1.638 | 1.00 | |
| 165_V | 169_R | 1.585 | 1.00 | |
| 168_I | 173_A | 1.538 | 1.00 | |
| 207_T | 240_I | 1.519 | 1.00 | |
| 159_A | 190_L | 1.511 | 1.00 | |
| 82_L | 138_V | 1.51 | 1.00 | |
| 149_L | 195_S | 1.5 | 1.00 | |
| 203_V | 247_L | 1.458 | 1.00 | |
| 169_R | 175_K | 1.453 | 1.00 | |
| 250_L | 253_R | 1.453 | 1.00 | |
| 74_Q | 78_W | 1.45 | 1.00 | |
| 95_A | 157_V | 1.446 | 1.00 | |
| 95_A | 158_E | 1.444 | 1.00 | |
| 168_I | 182_G | 1.426 | 1.00 | |
| 173_A | 177_E | 1.421 | 1.00 | |
| 94_S | 108_R | 1.415 | 1.00 | |
| 67_T | 70_A | 1.407 | 0.99 | |
| 123_A | 140_A | 1.402 | 0.99 | |
| 74_Q | 134_P | 1.397 | 0.99 | |
| 250_L | 254_L | 1.387 | 0.99 | |
| 134_P | 138_V | 1.373 | 0.99 | |
| 153_L | 191_L | 1.367 | 0.99 | |
| 89_P | 93_M | 1.361 | 0.99 | |
| 87_S | 149_L | 1.351 | 0.99 | |
| 249_F | 252_Q | 1.351 | 0.99 | |
| 86_L | 142_F | 1.341 | 0.99 | |
| 177_E | 181_Y | 1.318 | 0.99 | |
| 75_I | 209_V | 1.308 | 0.99 | |
| 149_L | 198_R | 1.304 | 0.99 | |
| 126_F | 140_A | 1.304 | 0.99 | |
| 117_I | 144_H | 1.277 | 0.99 | |
| 123_A | 208_V | 1.262 | 0.99 | |
| 88_I | 153_L | 1.258 | 0.99 | |
| 90_F | 107_V | 1.249 | 0.99 | |
| 157_V | 183_V | 1.242 | 0.98 | |
| 133_G | 214_A | 1.234 | 0.98 | |
| 64_D | 67_T | 1.229 | 0.98 | |
| 174_N | 178_E | 1.21 | 0.98 | |
| 246_L | 250_L | 1.202 | 0.98 | |
| 76_A | 206_A | 1.191 | 0.98 | |
| 79_G | 142_F | 1.19 | 0.98 | |
| 101_W | 105_Q | 1.19 | 0.98 | |
| 79_G | 202_N | 1.179 | 0.98 | |
| 91_G | 157_V | 1.168 | 0.97 | |
| 80_T | 202_N | 1.166 | 0.97 | |
| 106_P | 110_L | 1.143 | 0.97 | |
| 201_S | 205_S | 1.139 | 0.97 | |
| 224_A | 230_F | 1.117 | 0.96 | |
| 62_W | 66_L | 1.114 | 0.96 | |
| 109_R | 113_A | 1.098 | 0.96 | |
| 114_C | 143_I | 1.097 | 0.96 | |
| 77_V | 81_A | 1.089 | 0.96 | |
| 79_G | 141_L | 1.086 | 0.96 | |
| 175_K | 179_I | 1.086 | 0.96 | |
| 138_V | 142_F | 1.084 | 0.96 | |
| 81_A | 85_V | 1.079 | 0.95 | |
| 177_E | 180_L | 1.067 | 0.95 | |
| 123_A | 209_V | 1.063 | 0.95 | |
| 72_T | 203_V | 1.059 | 0.95 | |
| 221_L | 233_T | 1.045 | 0.94 | |
| 122_F | 144_H | 1.044 | 0.94 | |
| 104_Y | 108_R | 1.042 | 0.94 | |
| 151_K | 154_S | 1.04 | 0.94 | |
| 67_T | 71_V | 1.039 | 0.94 | |
| 141_L | 206_A | 1.034 | 0.94 | |
| 219_V | 222_W | 1.033 | 0.94 | |
| 87_S | 150_S | 1.026 | 0.94 | |
| 135_F | 139_L | 1.026 | 0.94 | |
| 124_M | 128_V | 1.024 | 0.93 | |
| 165_V | 183_V | 1.02 | 0.93 | |
| 144_H | 205_S | 1.009 | 0.93 | |
| 78_W | 81_A | 1.006 | 0.93 | |
| 160_I | 187_V | 1.003 | 0.93 | |
| 238_V | 242_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3tuiA | 4 | 0.7838 | 99.9 | 0.568 | Contact Map | 0.802 |
| 3d31C | 2 | 0.9575 | 99.9 | 0.574 | Contact Map | 0.595 |
| 2onkC | 4 | 0.9575 | 99.9 | 0.589 | Contact Map | 0.652 |
| 3rlfF | 1 | 0.9884 | 99.9 | 0.604 | Contact Map | 0.69 |
| 3rlfG | 1 | 0.9807 | 99.8 | 0.633 | Contact Map | 0.524 |
| 3rqwA | 10 | 0.4363 | 3.4 | 0.962 | Contact Map | 0.29 |
| 1rh5B | 1 | 0.2703 | 1.9 | 0.966 | Contact Map | 0.664 |
| 3w9iA | 6 | 0.8494 | 1.5 | 0.968 | Contact Map | 0.115 |
| 4dx5A | 3 | 0.861 | 1.4 | 0.969 | Contact Map | 0.192 |
| 2ksfA | 1 | 0.39 | 1.2 | 0.97 | Contact Map | 0.354 |
Sequence Conservation (Image Generated using WebLogo v3)