| UniProt: | P0AEU3 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10007 | ||
| Length: | 238 (223) | ||
| Sequences: | 8047 | ||
| Seq/Len: | 36.09 |
| HISM
Paralog alert: 0.91 [within 20: 0.54] - ratio of genomes with paralogs Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 36_I | 110_T | 3.561 | 1.00 | |
| 105_T | 177_A | 3.487 | 1.00 | |
| 164_S | 221_F | 3.073 | 1.00 | |
| 198_Q | 201_T | 2.951 | 1.00 | |
| 142_S | 145_K | 2.936 | 1.00 | |
| 47_G | 59_I | 2.812 | 1.00 | |
| 136_A | 146_M | 2.81 | 1.00 | |
| 189_A | 206_A | 2.726 | 1.00 | |
| 24_A | 28_W | 2.669 | 1.00 | |
| 69_T | 74_Q | 2.647 | 1.00 | |
| 44_L | 114_C | 2.5 | 1.00 | |
| 133_I | 146_M | 2.397 | 1.00 | |
| 132_E | 154_S | 2.384 | 1.00 | |
| 144_F | 148_R | 2.346 | 1.00 | |
| 54_Y | 58_P | 2.337 | 1.00 | |
| 54_Y | 57_F | 2.183 | 1.00 | |
| 30_L | 171_L | 2.162 | 1.00 | |
| 45_A | 121_F | 2.159 | 1.00 | |
| 44_L | 118_T | 2.129 | 1.00 | |
| 63_T | 118_T | 2.084 | 1.00 | |
| 124_A | 159_A | 2.068 | 1.00 | |
| 219_S | 223_R | 1.943 | 1.00 | |
| 48_R | 60_W | 1.914 | 1.00 | |
| 127_S | 158_I | 1.911 | 1.00 | |
| 211_L | 215_Y | 1.876 | 1.00 | |
| 23_V | 213_I | 1.783 | 1.00 | |
| 187_K | 191_D | 1.774 | 1.00 | |
| 25_I | 28_W | 1.752 | 1.00 | |
| 30_L | 174_T | 1.742 | 1.00 | |
| 40_L | 114_C | 1.739 | 1.00 | |
| 32_L | 106_V | 1.735 | 1.00 | |
| 133_I | 137_R | 1.731 | 1.00 | |
| 117_T | 163_Y | 1.703 | 1.00 | |
| 78_F | 108_A | 1.689 | 1.00 | |
| 193_N | 199_P | 1.682 | 1.00 | |
| 137_R | 146_M | 1.68 | 1.00 | |
| 28_W | 102_L | 1.665 | 1.00 | |
| 100_S | 103_N | 1.627 | 1.00 | |
| 223_R | 226_K | 1.618 | 1.00 | |
| 215_Y | 219_S | 1.601 | 1.00 | |
| 49_V | 125_I | 1.593 | 1.00 | |
| 34_V | 167_V | 1.535 | 1.00 | |
| 69_T | 112_N | 1.51 | 1.00 | |
| 29_L | 177_A | 1.5 | 1.00 | |
| 142_S | 146_M | 1.492 | 1.00 | |
| 143_T | 147_Y | 1.488 | 1.00 | |
| 220_L | 223_R | 1.487 | 1.00 | |
| 219_S | 222_R | 1.487 | 1.00 | |
| 74_Q | 112_N | 1.479 | 1.00 | |
| 189_A | 202_A | 1.472 | 1.00 | |
| 66_F | 111_L | 1.448 | 1.00 | |
| 42_L | 121_F | 1.431 | 1.00 | |
| 102_L | 106_V | 1.43 | 1.00 | |
| 53_K | 57_F | 1.422 | 1.00 | |
| 49_V | 126_R | 1.413 | 1.00 | |
| 220_L | 224_A | 1.394 | 0.99 | |
| 36_I | 106_V | 1.394 | 0.99 | |
| 44_L | 59_I | 1.39 | 0.99 | |
| 141_F | 145_K | 1.376 | 0.99 | |
| 119_E | 122_A | 1.374 | 0.99 | |
| 75_L | 108_A | 1.37 | 0.99 | |
| 47_G | 50_S | 1.363 | 0.99 | |
| 43_F | 47_G | 1.348 | 0.99 | |
| 145_K | 149_C | 1.347 | 0.99 | |
| 52_N | 57_F | 1.327 | 0.99 | |
| 53_K | 56_Q | 1.281 | 0.99 | |
| 145_K | 148_R | 1.266 | 0.99 | |
| 177_A | 184_D | 1.265 | 0.99 | |
| 25_I | 182_V | 1.243 | 0.98 | |
| 223_R | 227_R | 1.24 | 0.98 | |
| 193_N | 203_F | 1.217 | 0.98 | |
| 175_A | 210_Y | 1.216 | 0.98 | |
| 32_L | 110_T | 1.205 | 0.98 | |
| 48_R | 119_E | 1.194 | 0.98 | |
| 37_G | 113_T | 1.187 | 0.98 | |
| 121_F | 159_A | 1.187 | 0.98 | |
| 137_R | 143_T | 1.18 | 0.98 | |
| 117_T | 166_E | 1.173 | 0.98 | |
| 41_A | 117_T | 1.168 | 0.97 | |
| 47_G | 55_I | 1.158 | 0.97 | |
| 39_V | 43_F | 1.149 | 0.97 | |
| 28_W | 32_L | 1.147 | 0.97 | |
| 58_P | 61_L | 1.139 | 0.97 | |
| 57_F | 61_L | 1.127 | 0.97 | |
| 171_L | 217_L | 1.121 | 0.97 | |
| 183_P | 187_K | 1.121 | 0.97 | |
| 35_V | 39_V | 1.109 | 0.96 | |
| 128_V | 158_I | 1.106 | 0.96 | |
| 141_F | 149_C | 1.094 | 0.96 | |
| 169_L | 173_S | 1.093 | 0.96 | |
| 122_A | 126_R | 1.086 | 0.96 | |
| 64_Y | 215_Y | 1.077 | 0.95 | |
| 227_R | 230_Q | 1.074 | 0.95 | |
| 33_S | 110_T | 1.061 | 0.95 | |
| 56_Q | 60_W | 1.061 | 0.95 | |
| 136_A | 150_I | 1.056 | 0.95 | |
| 120_I | 166_E | 1.055 | 0.95 | |
| 187_K | 190_R | 1.045 | 0.94 | |
| 133_I | 151_I | 1.04 | 0.94 | |
| 188_I | 191_D | 1.037 | 0.94 | |
| 208_V | 212_I | 1.035 | 0.94 | |
| 58_P | 62_F | 1.03 | 0.94 | |
| 20_F | 24_A | 1.029 | 0.94 | |
| 147_Y | 152_L | 1.028 | 0.94 | |
| 75_L | 177_A | 1.027 | 0.94 | |
| 103_N | 107_L | 1.026 | 0.94 | |
| 61_L | 65_I | 1.023 | 0.93 | |
| 102_L | 182_V | 1.015 | 0.93 | |
| 171_L | 213_I | 1.009 | 0.93 | |
| 74_Q | 78_F | 1 | 0.92 | |
| 66_F | 115_A | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3tuiA | 4 | 0.8824 | 99.9 | 0.623 | Contact Map | 0.782 |
| 2onkC | 4 | 0.9664 | 99.9 | 0.648 | Contact Map | 0.59 |
| 3d31C | 2 | 0.9622 | 99.9 | 0.656 | Contact Map | 0.541 |
| 3rlfF | 1 | 0.9664 | 99.9 | 0.657 | Contact Map | 0.614 |
| 3rlfG | 1 | 0.9622 | 99.8 | 0.683 | Contact Map | 0.493 |
| 3e7lA | 4 | 0.2647 | 7 | 0.962 | Contact Map | 0.608 |
| 4f4lA | 4 | 0.3361 | 5 | 0.965 | Contact Map | 0.278 |
| 3zjzA | 4 | 0.4622 | 4.9 | 0.965 | Contact Map | 0.344 |
| 1g2hA | 1 | 0.2563 | 2.8 | 0.969 | Contact Map | 0.393 |
| 4l5eA | 1 | 0.1933 | 2.8 | 0.969 | Contact Map | 0.524 |
Sequence Conservation (Image Generated using WebLogo v3)