| UniProt: | P77616 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14229 | ||
| Length: | 249 (215) | ||
| Sequences: | 1320 | ||
| Seq/Len: | 6.14 |
| YQIH
Paralog alert: 0.90 [within 20: 0.51] - ratio of genomes with paralogs Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 102_L | 110_F | 2.915 | 1.00 | |
| 29_P | 135_L | 2.887 | 1.00 | |
| 178_T | 197_M | 2.805 | 1.00 | |
| 176_H | 199_T | 2.708 | 1.00 | |
| 109_L | 197_M | 2.701 | 1.00 | |
| 106_R | 201_F | 2.532 | 1.00 | |
| 37_N | 40_D | 2.525 | 1.00 | |
| 199_T | 202_S | 2.451 | 1.00 | |
| 138_F | 197_M | 2.427 | 1.00 | |
| 158_E | 170_N | 2.321 | 1.00 | |
| 170_N | 203_Y | 2.272 | 1.00 | |
| 34_I | 112_F | 2.252 | 1.00 | |
| 34_I | 93_M | 2.232 | 1.00 | |
| 62_I | 137_L | 2.196 | 1.00 | |
| 34_I | 43_E | 2.183 | 1.00 | |
| 56_Y | 116_E | 2.151 | 1.00 | |
| 61_W | 113_N | 2.097 | 1.00 | |
| 63_E | 134_A | 2.056 | 1.00 | |
| 55_P | 84_N | 1.991 | 1.00 | |
| 169_F | 206_T | 1.981 | 1.00 | |
| 38_E | 104_K | 1.933 | 1.00 | |
| 55_P | 82_R | 1.929 | 1.00 | |
| 103_P | 108_T | 1.884 | 1.00 | |
| 113_N | 134_A | 1.867 | 1.00 | |
| 144_I | 175_Y | 1.709 | 1.00 | |
| 159_I | 169_F | 1.694 | 1.00 | |
| 221_N | 227_S | 1.676 | 1.00 | |
| 39_S | 142_K | 1.648 | 1.00 | |
| 63_E | 113_N | 1.625 | 1.00 | |
| 115_R | 132_Q | 1.624 | 1.00 | |
| 109_L | 178_T | 1.609 | 1.00 | |
| 103_P | 106_R | 1.591 | 0.99 | |
| 37_N | 43_E | 1.586 | 0.99 | |
| 74_I | 93_M | 1.585 | 0.99 | |
| 168_R | 205_N | 1.562 | 0.99 | |
| 156_K | 173_M | 1.551 | 0.99 | |
| 95_T | 98_K | 1.549 | 0.99 | |
| 84_N | 87_E | 1.539 | 0.99 | |
| 93_M | 137_L | 1.518 | 0.99 | |
| 157_V | 169_F | 1.488 | 0.99 | |
| 27_I | 83_L | 1.483 | 0.99 | |
| 198_V | 204_A | 1.472 | 0.99 | |
| 151_V | 177_V | 1.456 | 0.99 | |
| 177_V | 219_Y | 1.448 | 0.99 | |
| 29_P | 114_V | 1.443 | 0.99 | |
| 221_N | 225_G | 1.392 | 0.98 | |
| 138_F | 176_H | 1.39 | 0.98 | |
| 178_T | 219_Y | 1.382 | 0.98 | |
| 109_L | 138_F | 1.376 | 0.98 | |
| 168_R | 203_Y | 1.357 | 0.98 | |
| 160_I | 168_R | 1.355 | 0.98 | |
| 29_P | 45_L | 1.351 | 0.98 | |
| 76_T | 91_I | 1.339 | 0.98 | |
| 34_I | 135_L | 1.325 | 0.97 | |
| 46_K | 88_Q | 1.323 | 0.97 | |
| 47_L | 58_A | 1.323 | 0.97 | |
| 28_I | 31_R | 1.312 | 0.97 | |
| 160_I | 170_N | 1.304 | 0.97 | |
| 36_M | 43_E | 1.3 | 0.97 | |
| 162_R | 168_R | 1.289 | 0.97 | |
| 52_K | 86_S | 1.284 | 0.97 | |
| 63_E | 111_Y | 1.281 | 0.97 | |
| 148_D | 151_V | 1.261 | 0.96 | |
| 146_L | 150_G | 1.257 | 0.96 | |
| 58_A | 81_V | 1.234 | 0.96 | |
| 26_A | 116_E | 1.207 | 0.95 | |
| 219_Y | 227_S | 1.174 | 0.94 | |
| 117_I | 131_M | 1.171 | 0.94 | |
| 89_I | 115_R | 1.168 | 0.93 | |
| 162_R | 165_G | 1.159 | 0.93 | |
| 159_I | 182_I | 1.151 | 0.93 | |
| 111_Y | 115_R | 1.145 | 0.93 | |
| 98_K | 101_Q | 1.143 | 0.93 | |
| 76_T | 112_F | 1.142 | 0.92 | |
| 91_I | 112_F | 1.141 | 0.92 | |
| 159_I | 197_M | 1.137 | 0.92 | |
| 76_T | 93_M | 1.136 | 0.92 | |
| 188_T | 191_P | 1.105 | 0.91 | |
| 179_L | 198_V | 1.098 | 0.90 | |
| 64_D | 68_N | 1.095 | 0.90 | |
| 60_T | 114_V | 1.091 | 0.90 | |
| 51_S | 116_E | 1.088 | 0.90 | |
| 91_I | 114_V | 1.083 | 0.90 | |
| 55_P | 119_P | 1.081 | 0.89 | |
| 165_G | 205_N | 1.074 | 0.89 | |
| 60_T | 91_I | 1.074 | 0.89 | |
| 107_E | 140_R | 1.058 | 0.88 | |
| 238_N | 241_N | 1.057 | 0.88 | |
| 157_V | 179_L | 1.055 | 0.88 | |
| 181_Y | 218_G | 1.051 | 0.88 | |
| 215_F | 219_Y | 1.048 | 0.87 | |
| 90_Q | 132_Q | 1.039 | 0.87 | |
| 198_V | 202_S | 1.038 | 0.87 | |
| 89_I | 116_E | 1.034 | 0.87 | |
| 114_V | 135_L | 1.022 | 0.86 | |
| 150_G | 155_E | 1.021 | 0.86 | |
| 125_N | 134_A | 1.02 | 0.85 | |
| 95_T | 139_W | 1.02 | 0.85 | |
| 56_Y | 115_R | 1.019 | 0.85 | |
| 57_L | 175_Y | 1.017 | 0.85 | |
| 57_L | 115_R | 1.016 | 0.85 | |
| 61_W | 134_A | 1 | 0.84 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2xg5A | 1 | 0.8675 | 100 | 0.164 | Contact Map | 0.794 |
| 4djmA | 8 | 0.8755 | 100 | 0.185 | Contact Map | 0.804 |
| 3gfuC | 2 | 0.8434 | 100 | 0.192 | Contact Map | 0.688 |
| 1klfA | 8 | 0.8072 | 100 | 0.195 | Contact Map | 0.784 |
| 2co7B | 1 | 0.8514 | 100 | 0.198 | Contact Map | 0.733 |
| 1l4iA | 2 | 0.8032 | 100 | 0.204 | Contact Map | 0.774 |
| 4ay0A | 2 | 0.8554 | 100 | 0.209 | Contact Map | 0.768 |
| 3q48A | 2 | 0.9438 | 100 | 0.229 | Contact Map | 0.803 |
| 1mspA | 2 | 0.4538 | 37.1 | 0.952 | Contact Map | 0.547 |
| 1z9lA | 1 | 0.4578 | 12.7 | 0.961 | Contact Map | 0.698 |
Sequence Conservation (Image Generated using WebLogo v3)