| UniProt: | P75856 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13710 | ||
| Length: | 233 (205) | ||
| Sequences: | 1342 | ||
| Seq/Len: | 6.55 |
| ELFD
Paralog alert: 0.90 [within 20: 0.51] - ratio of genomes with paralogs Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 104_L | 112_F | 2.917 | 1.00 | |
| 34_L | 139_I | 2.831 | 1.00 | |
| 179_T | 194_M | 2.795 | 1.00 | |
| 177_F | 196_S | 2.773 | 1.00 | |
| 42_S | 45_E | 2.556 | 1.00 | |
| 111_L | 194_M | 2.55 | 1.00 | |
| 196_S | 199_D | 2.527 | 1.00 | |
| 142_F | 194_M | 2.459 | 1.00 | |
| 171_S | 200_K | 2.373 | 1.00 | |
| 108_R | 198_F | 2.344 | 1.00 | |
| 160_R | 171_S | 2.268 | 1.00 | |
| 39_L | 114_T | 2.219 | 1.00 | |
| 67_V | 141_L | 2.198 | 1.00 | |
| 61_Y | 118_A | 2.173 | 1.00 | |
| 39_L | 48_I | 2.156 | 1.00 | |
| 66_W | 115_S | 2.111 | 1.00 | |
| 68_M | 138_V | 2.067 | 1.00 | |
| 39_L | 97_I | 2.057 | 1.00 | |
| 170_V | 203_F | 2.038 | 1.00 | |
| 60_P | 86_V | 2.015 | 1.00 | |
| 60_P | 88_N | 1.967 | 1.00 | |
| 43_E | 106_K | 1.911 | 1.00 | |
| 105_A | 110_T | 1.897 | 1.00 | |
| 115_S | 138_V | 1.82 | 1.00 | |
| 117_R | 136_Q | 1.707 | 1.00 | |
| 78_F | 97_I | 1.626 | 1.00 | |
| 152_L | 155_A | 1.624 | 1.00 | |
| 148_L | 176_Y | 1.614 | 1.00 | |
| 68_M | 115_S | 1.613 | 1.00 | |
| 105_A | 108_R | 1.588 | 1.00 | |
| 161_C | 170_V | 1.566 | 0.99 | |
| 88_N | 91_N | 1.545 | 0.99 | |
| 111_L | 179_T | 1.542 | 0.99 | |
| 99_Y | 102_A | 1.528 | 0.99 | |
| 158_K | 174_T | 1.52 | 0.99 | |
| 44_G | 146_K | 1.517 | 0.99 | |
| 97_I | 141_L | 1.508 | 0.99 | |
| 57_P | 90_A | 1.459 | 0.99 | |
| 32_I | 87_L | 1.449 | 0.99 | |
| 169_T | 202_Q | 1.437 | 0.99 | |
| 159_L | 170_V | 1.436 | 0.99 | |
| 164_S | 169_T | 1.417 | 0.99 | |
| 80_I | 95_L | 1.411 | 0.99 | |
| 42_S | 48_I | 1.408 | 0.99 | |
| 220_N | 224_A | 1.399 | 0.99 | |
| 169_T | 200_K | 1.396 | 0.99 | |
| 154_E | 157_A | 1.388 | 0.98 | |
| 156_P | 216_Y | 1.376 | 0.98 | |
| 195_I | 201_Y | 1.374 | 0.98 | |
| 155_A | 178_I | 1.359 | 0.98 | |
| 51_G | 92_E | 1.329 | 0.98 | |
| 164_S | 167_M | 1.32 | 0.98 | |
| 34_L | 116_V | 1.305 | 0.97 | |
| 162_T | 169_T | 1.304 | 0.97 | |
| 142_F | 177_F | 1.303 | 0.97 | |
| 39_L | 139_I | 1.295 | 0.97 | |
| 179_T | 218_T | 1.29 | 0.97 | |
| 34_L | 50_L | 1.282 | 0.97 | |
| 95_L | 114_T | 1.277 | 0.97 | |
| 220_N | 226_T | 1.269 | 0.97 | |
| 33_G | 36_A | 1.267 | 0.97 | |
| 52_V | 63_I | 1.254 | 0.96 | |
| 178_I | 218_T | 1.252 | 0.96 | |
| 111_L | 142_F | 1.243 | 0.96 | |
| 161_C | 183_L | 1.243 | 0.96 | |
| 41_Y | 48_I | 1.241 | 0.96 | |
| 155_A | 218_T | 1.223 | 0.96 | |
| 80_I | 114_T | 1.212 | 0.96 | |
| 162_T | 171_S | 1.208 | 0.95 | |
| 68_M | 113_F | 1.203 | 0.95 | |
| 63_I | 85_F | 1.194 | 0.95 | |
| 65_S | 95_L | 1.189 | 0.95 | |
| 26_A | 30_G | 1.187 | 0.95 | |
| 80_I | 97_I | 1.182 | 0.95 | |
| 93_N | 117_R | 1.172 | 0.94 | |
| 195_I | 199_D | 1.163 | 0.94 | |
| 95_L | 116_V | 1.155 | 0.94 | |
| 60_P | 121_S | 1.148 | 0.93 | |
| 65_S | 116_V | 1.139 | 0.93 | |
| 113_F | 117_R | 1.139 | 0.93 | |
| 119_V | 135_T | 1.133 | 0.93 | |
| 180_L | 195_I | 1.11 | 0.92 | |
| 99_Y | 143_W | 1.092 | 0.91 | |
| 94_L | 136_Q | 1.083 | 0.91 | |
| 150_Y | 154_E | 1.078 | 0.90 | |
| 31_G | 118_A | 1.071 | 0.90 | |
| 52_V | 87_L | 1.071 | 0.90 | |
| 129_N | 138_V | 1.065 | 0.90 | |
| 152_L | 156_P | 1.058 | 0.89 | |
| 99_Y | 103_P | 1.054 | 0.89 | |
| 159_L | 180_L | 1.044 | 0.88 | |
| 170_V | 180_L | 1.042 | 0.88 | |
| 109_E | 144_R | 1.032 | 0.88 | |
| 66_W | 138_V | 1.03 | 0.87 | |
| 87_L | 92_E | 1.029 | 0.87 | |
| 61_Y | 117_R | 1.028 | 0.87 | |
| 36_A | 117_R | 1.026 | 0.87 | |
| 116_V | 139_I | 1.014 | 0.86 | |
| 167_M | 202_Q | 1.01 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4djmA | 8 | 0.9571 | 100 | 0.202 | Contact Map | 0.805 |
| 1klfA | 8 | 0.8627 | 100 | 0.21 | Contact Map | 0.794 |
| 2co7B | 1 | 0.9142 | 100 | 0.218 | Contact Map | 0.731 |
| 1l4iA | 2 | 0.8627 | 100 | 0.218 | Contact Map | 0.781 |
| 4ay0A | 2 | 0.9099 | 100 | 0.228 | Contact Map | 0.765 |
| 2xg5A | 1 | 0.8498 | 100 | 0.231 | Contact Map | 0.798 |
| 3gfuC | 2 | 0.8326 | 100 | 0.239 | Contact Map | 0.706 |
| 3q48A | 2 | 0.9785 | 100 | 0.262 | Contact Map | 0.816 |
| 1mspA | 2 | 0.485 | 34.3 | 0.955 | Contact Map | 0.553 |
| 2ys4A | 1 | 0.4936 | 12.2 | 0.963 | Contact Map | 0.453 |
Sequence Conservation (Image Generated using WebLogo v3)