| UniProt: | P77249 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13882 | ||
| Length: | 230 (208) | ||
| Sequences: | 1362 | ||
| Seq/Len: | 6.55 |
| SFMC
Paralog alert: 0.90 [within 20: 0.52] - ratio of genomes with paralogs Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 99_L | 107_F | 2.919 | 1.00 | |
| 29_L | 136_M | 2.827 | 1.00 | |
| 176_T | 191_M | 2.817 | 1.00 | |
| 174_Y | 193_A | 2.769 | 1.00 | |
| 106_L | 191_M | 2.713 | 1.00 | |
| 193_A | 196_V | 2.592 | 1.00 | |
| 139_F | 191_M | 2.496 | 1.00 | |
| 37_P | 40_A | 2.452 | 1.00 | |
| 103_R | 195_R | 2.44 | 1.00 | |
| 168_H | 197_N | 2.376 | 1.00 | |
| 157_K | 168_H | 2.215 | 1.00 | |
| 34_I | 109_M | 2.127 | 1.00 | |
| 61_W | 110_N | 2.124 | 1.00 | |
| 62_I | 138_L | 2.123 | 1.00 | |
| 34_I | 43_T | 2.112 | 1.00 | |
| 56_F | 113_T | 2.111 | 1.00 | |
| 34_I | 92_I | 2.036 | 1.00 | |
| 63_E | 135_R | 2.035 | 1.00 | |
| 167_V | 200_I | 2.028 | 1.00 | |
| 38_A | 101_A | 2.016 | 1.00 | |
| 100_A | 105_S | 2.014 | 1.00 | |
| 55_R | 83_E | 1.988 | 1.00 | |
| 55_R | 81_V | 1.971 | 1.00 | |
| 110_N | 135_R | 1.877 | 1.00 | |
| 145_L | 173_F | 1.717 | 1.00 | |
| 112_K | 133_L | 1.689 | 1.00 | |
| 100_A | 103_R | 1.672 | 1.00 | |
| 39_D | 143_I | 1.651 | 1.00 | |
| 73_F | 92_I | 1.641 | 1.00 | |
| 63_E | 110_N | 1.641 | 1.00 | |
| 158_F | 167_V | 1.618 | 1.00 | |
| 151_E | 154_D | 1.597 | 1.00 | |
| 149_P | 152_A | 1.596 | 1.00 | |
| 83_E | 86_S | 1.585 | 1.00 | |
| 106_L | 176_T | 1.568 | 0.99 | |
| 155_T | 171_S | 1.52 | 0.99 | |
| 216_N | 222_T | 1.499 | 0.99 | |
| 92_I | 138_L | 1.494 | 0.99 | |
| 216_N | 220_S | 1.48 | 0.99 | |
| 27_I | 82_S | 1.47 | 0.99 | |
| 166_N | 199_Q | 1.468 | 0.99 | |
| 192_A | 198_S | 1.466 | 0.99 | |
| 156_L | 167_V | 1.459 | 0.99 | |
| 175_V | 214_T | 1.453 | 0.99 | |
| 37_P | 43_T | 1.445 | 0.99 | |
| 152_A | 175_V | 1.441 | 0.99 | |
| 161_S | 166_N | 1.428 | 0.99 | |
| 52_T | 85_K | 1.423 | 0.99 | |
| 94_Y | 97_P | 1.402 | 0.99 | |
| 75_I | 90_L | 1.378 | 0.98 | |
| 29_L | 111_V | 1.364 | 0.98 | |
| 46_W | 87_E | 1.361 | 0.98 | |
| 159_S | 166_N | 1.352 | 0.98 | |
| 166_N | 197_N | 1.349 | 0.98 | |
| 47_I | 58_V | 1.338 | 0.98 | |
| 139_F | 174_Y | 1.325 | 0.98 | |
| 34_I | 136_M | 1.316 | 0.98 | |
| 176_T | 214_T | 1.303 | 0.97 | |
| 106_L | 139_F | 1.283 | 0.97 | |
| 28_A | 31_A | 1.271 | 0.97 | |
| 158_F | 180_L | 1.268 | 0.97 | |
| 55_R | 116_S | 1.267 | 0.97 | |
| 210_L | 214_T | 1.262 | 0.97 | |
| 63_E | 108_W | 1.239 | 0.96 | |
| 36_Y | 43_T | 1.229 | 0.96 | |
| 29_L | 45_V | 1.221 | 0.96 | |
| 161_S | 164_Y | 1.211 | 0.95 | |
| 75_I | 92_I | 1.205 | 0.95 | |
| 58_V | 80_F | 1.204 | 0.95 | |
| 88_N | 112_K | 1.195 | 0.95 | |
| 90_L | 109_M | 1.189 | 0.95 | |
| 159_S | 168_H | 1.178 | 0.95 | |
| 94_Y | 140_L | 1.17 | 0.94 | |
| 114_I | 132_I | 1.157 | 0.94 | |
| 164_Y | 199_Q | 1.154 | 0.94 | |
| 90_L | 111_V | 1.153 | 0.94 | |
| 26_G | 113_T | 1.151 | 0.94 | |
| 192_A | 196_V | 1.147 | 0.93 | |
| 60_S | 90_L | 1.14 | 0.93 | |
| 75_I | 109_M | 1.131 | 0.93 | |
| 108_W | 112_K | 1.13 | 0.93 | |
| 94_Y | 98_P | 1.122 | 0.92 | |
| 60_S | 111_V | 1.117 | 0.92 | |
| 147_E | 151_E | 1.106 | 0.92 | |
| 153_P | 212_F | 1.097 | 0.91 | |
| 156_L | 177_L | 1.089 | 0.91 | |
| 89_T | 133_L | 1.07 | 0.90 | |
| 152_A | 214_T | 1.069 | 0.90 | |
| 167_V | 177_L | 1.063 | 0.90 | |
| 82_S | 87_E | 1.056 | 0.89 | |
| 177_L | 192_A | 1.043 | 0.88 | |
| 88_N | 113_T | 1.039 | 0.88 | |
| 47_I | 82_S | 1.037 | 0.88 | |
| 104_E | 141_R | 1.035 | 0.88 | |
| 56_F | 112_K | 1.034 | 0.88 | |
| 126_N | 135_R | 1.031 | 0.88 | |
| 158_F | 191_M | 1.028 | 0.87 | |
| 51_H | 113_T | 1.005 | 0.86 | |
| 179_N | 213_Q | 1.004 | 0.86 | |
| 149_P | 153_P | 1.003 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1klfA | 8 | 0.887 | 100 | 0.158 | Contact Map | 0.79 |
| 4djmA | 8 | 0.9739 | 100 | 0.163 | Contact Map | 0.804 |
| 1l4iA | 2 | 0.8826 | 100 | 0.169 | Contact Map | 0.778 |
| 2co7B | 1 | 0.9348 | 100 | 0.173 | Contact Map | 0.732 |
| 4ay0A | 2 | 0.9261 | 100 | 0.186 | Contact Map | 0.762 |
| 2xg5A | 1 | 0.8609 | 100 | 0.205 | Contact Map | 0.792 |
| 3gfuC | 2 | 0.8435 | 100 | 0.209 | Contact Map | 0.702 |
| 3q48A | 2 | 0.9696 | 100 | 0.224 | Contact Map | 0.803 |
| 1mspA | 2 | 0.4957 | 35.3 | 0.953 | Contact Map | 0.577 |
| 1z9lA | 1 | 0.5043 | 12.9 | 0.961 | Contact Map | 0.695 |
Sequence Conservation (Image Generated using WebLogo v3)