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OPENSEQ.org
FIMC - Chaperone protein FimC
UniProt: P31697 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10310
Length: 241 (210)
Sequences: 1345
Seq/Len: 6.40
FIMC
Paralog alert: 0.90 [within 20: 0.51] - ratio of genomes with paralogs
Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
40_L 147_I 2.959 1.00
187_T 202_L 2.9 1.00
111_L 119_F 2.88 1.00
185_Y 204_P 2.793 1.00
118_L 202_L 2.766 1.00
204_P 207_G 2.643 1.00
48_P 51_Q 2.472 1.00
150_Y 202_L 2.417 1.00
115_R 206_M 2.412 1.00
179_I 208_E 2.368 1.00
45_V 54_E 2.198 1.00
168_R 179_I 2.196 1.00
73_V 149_L 2.177 1.00
45_V 103_I 2.144 1.00
72_W 122_N 2.144 1.00
45_V 121_M 2.135 1.00
67_Y 125_A 2.126 1.00
74_E 146_R 2.076 1.00
178_L 211_V 2.071 1.00
66_T 94_K 2.016 1.00
66_T 92_A 2.004 1.00
49_A 113_Q 1.94 1.00
112_P 117_S 1.903 1.00
122_N 146_R 1.864 1.00
156_L 184_Y 1.754 1.00
124_K 144_I 1.725 1.00
50_G 154_A 1.711 1.00
160_P 163_A 1.686 1.00
94_K 97_K 1.685 1.00
74_E 122_N 1.662 1.00
112_P 115_R 1.661 1.00
84_F 103_I 1.635 1.00
169_F 178_L 1.633 1.00
118_L 187_T 1.606 1.00
103_I 149_L 1.533 0.99
166_K 182_T 1.525 0.99
177_T 210_T 1.521 0.99
227_N 231_A 1.479 0.99
203_V 209_S 1.479 0.99
38_V 93_M 1.466 0.99
162_Q 165_E 1.457 0.99
167_L 178_L 1.453 0.99
86_V 101_L 1.448 0.99
163_A 186_L 1.44 0.99
40_L 123_V 1.426 0.99
227_N 233_T 1.402 0.98
48_P 54_E 1.401 0.98
172_S 177_T 1.392 0.98
63_E 96_K 1.386 0.98
40_L 56_L 1.373 0.98
105_D 108_N 1.366 0.98
186_L 225_T 1.363 0.98
57_A 98_E 1.326 0.98
177_T 208_E 1.325 0.98
45_V 147_I 1.316 0.97
170_R 177_T 1.315 0.97
187_T 225_T 1.31 0.97
150_Y 185_Y 1.288 0.97
58_V 69_I 1.275 0.97
74_E 120_W 1.273 0.97
69_I 91_F 1.269 0.97
39_A 42_A 1.268 0.97
163_A 225_T 1.259 0.96
169_F 191_L 1.246 0.96
101_L 121_M 1.241 0.96
86_V 121_M 1.225 0.96
118_L 150_Y 1.222 0.96
99_N 124_K 1.194 0.95
170_R 179_I 1.192 0.95
86_V 103_I 1.183 0.94
37_G 125_A 1.182 0.94
164_A 223_Y 1.181 0.94
175_S 210_T 1.18 0.94
47_Y 54_E 1.176 0.94
75_N 79_V 1.175 0.94
105_D 109_N 1.161 0.94
172_S 175_S 1.155 0.93
203_V 207_G 1.152 0.93
105_D 151_Y 1.141 0.93
120_W 124_K 1.135 0.93
66_T 128_S 1.124 0.92
71_S 101_L 1.122 0.92
123_V 147_I 1.112 0.92
126_I 143_I 1.111 0.92
71_S 123_V 1.092 0.91
188_V 203_V 1.091 0.91
100_T 144_I 1.089 0.91
101_L 123_V 1.075 0.90
164_A 186_L 1.061 0.89
169_F 223_Y 1.058 0.89
58_V 93_M 1.051 0.88
67_Y 124_K 1.05 0.88
99_N 125_A 1.044 0.88
116_E 152_R 1.038 0.88
93_M 98_E 1.038 0.88
68_L 184_Y 1.018 0.86
167_L 188_V 1.012 0.86
62_D 125_A 1.011 0.86
169_F 202_L 1.009 0.86
188_V 225_T 1.007 0.85
190_E 224_R 1.007 0.85
72_W 146_R 1.001 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1klfA80.84231000.21Contact Map0.787
4djmA80.92531000.211Contact Map0.807
1l4iA20.84231000.22Contact Map0.773
2co7B10.89211000.222Contact Map0.732
4ay0A20.88381000.231Contact Map0.768
2xg5A10.82161000.254Contact Map0.796
3gfuC20.8051000.26Contact Map0.708
3q48A20.94191000.275Contact Map0.802
1mspA20.47339.10.954Contact Map0.569
1z9lA10.481317.50.962Contact Map0.69
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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