| UniProt: | P76290 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14033 | ||
| Length: | 247 (226) | ||
| Sequences: | 2773 | ||
| Seq/Len: | 12.27 |
| CMOA
Paralog alert: 0.53 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: BIOC CMOA SMTA TAM TEHB UBIE UBIG YAFE YJHP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 151_Y | 223_F | 3.248 | 1.00 | |
| 144_Q | 220_N | 3.083 | 1.00 | |
| 149_K | 152_Q | 3.014 | 1.00 | |
| 61_Y | 126_A | 2.836 | 1.00 | |
| 150_I | 160_L | 2.807 | 1.00 | |
| 59_Q | 84_K | 2.793 | 1.00 | |
| 92_P | 96_E | 2.768 | 1.00 | |
| 95_I | 115_E | 2.751 | 1.00 | |
| 29_P | 67_L | 2.697 | 1.00 | |
| 92_P | 115_E | 2.644 | 1.00 | |
| 127_S | 155_N | 2.617 | 1.00 | |
| 215_K | 219_H | 2.614 | 1.00 | |
| 86_I | 126_A | 2.554 | 1.00 | |
| 65_C | 87_A | 2.509 | 1.00 | |
| 64_G | 134_T | 2.501 | 1.00 | |
| 95_I | 113_V | 2.45 | 1.00 | |
| 119_R | 142_E | 2.275 | 1.00 | |
| 210_S | 213_T | 2.228 | 1.00 | |
| 84_K | 112_D | 2.166 | 1.00 | |
| 144_Q | 217_R | 2.128 | 1.00 | |
| 144_Q | 148_D | 2.097 | 1.00 | |
| 102_I | 113_V | 2.093 | 1.00 | |
| 29_P | 101_H | 2.059 | 1.00 | |
| 97_R | 100_R | 2.011 | 1.00 | |
| 93_A | 96_E | 1.996 | 1.00 | |
| 154_L | 158_G | 1.909 | 1.00 | |
| 154_L | 160_L | 1.882 | 1.00 | |
| 149_K | 153_G | 1.873 | 1.00 | |
| 88_I | 116_G | 1.864 | 1.00 | |
| 151_Y | 242_K | 1.825 | 1.00 | |
| 64_G | 131_L | 1.816 | 1.00 | |
| 87_A | 113_V | 1.772 | 1.00 | |
| 69_A | 101_H | 1.752 | 1.00 | |
| 86_I | 114_I | 1.737 | 1.00 | |
| 72_L | 102_I | 1.733 | 1.00 | |
| 138_L | 146_L | 1.729 | 1.00 | |
| 129_V | 150_I | 1.71 | 1.00 | |
| 71_T | 85_I | 1.695 | 1.00 | |
| 216_A | 220_N | 1.657 | 1.00 | |
| 50_A | 128_M | 1.643 | 1.00 | |
| 22_E | 93_A | 1.638 | 1.00 | |
| 117_D | 120_D | 1.613 | 1.00 | |
| 59_Q | 86_I | 1.584 | 1.00 | |
| 129_V | 153_G | 1.555 | 1.00 | |
| 65_C | 71_T | 1.555 | 1.00 | |
| 121_I | 153_G | 1.534 | 1.00 | |
| 76_R | 105_Y | 1.517 | 1.00 | |
| 144_Q | 221_A | 1.517 | 1.00 | |
| 123_I | 126_A | 1.506 | 1.00 | |
| 122_A | 149_K | 1.493 | 1.00 | |
| 88_I | 121_I | 1.48 | 1.00 | |
| 118_I | 134_T | 1.47 | 1.00 | |
| 218_L | 240_A | 1.462 | 1.00 | |
| 71_T | 111_V | 1.45 | 1.00 | |
| 71_T | 87_A | 1.433 | 1.00 | |
| 129_V | 154_L | 1.427 | 1.00 | |
| 99_R | 103_D | 1.418 | 1.00 | |
| 148_D | 220_N | 1.379 | 0.99 | |
| 216_A | 219_H | 1.37 | 0.99 | |
| 116_G | 122_A | 1.368 | 0.99 | |
| 86_I | 112_D | 1.362 | 0.99 | |
| 135_L | 147_L | 1.358 | 0.99 | |
| 154_L | 223_F | 1.329 | 0.99 | |
| 63_L | 118_I | 1.322 | 0.99 | |
| 63_L | 150_I | 1.292 | 0.99 | |
| 145_A | 148_D | 1.269 | 0.99 | |
| 160_L | 223_F | 1.264 | 0.99 | |
| 141_S | 213_T | 1.256 | 0.99 | |
| 121_I | 149_K | 1.243 | 0.98 | |
| 40_S | 73_S | 1.232 | 0.98 | |
| 60_V | 128_M | 1.229 | 0.98 | |
| 67_L | 97_R | 1.207 | 0.98 | |
| 211_V | 228_L | 1.197 | 0.98 | |
| 160_L | 218_L | 1.186 | 0.98 | |
| 96_E | 99_R | 1.173 | 0.98 | |
| 60_V | 74_V | 1.171 | 0.98 | |
| 218_L | 223_F | 1.167 | 0.97 | |
| 136_Q | 164_E | 1.162 | 0.97 | |
| 224_E | 243_A | 1.16 | 0.97 | |
| 98_C | 113_V | 1.143 | 0.97 | |
| 131_L | 160_L | 1.141 | 0.97 | |
| 67_L | 101_H | 1.134 | 0.97 | |
| 132_N | 163_S | 1.118 | 0.96 | |
| 59_Q | 155_N | 1.112 | 0.96 | |
| 147_L | 160_L | 1.108 | 0.96 | |
| 211_V | 215_K | 1.104 | 0.96 | |
| 126_A | 153_G | 1.095 | 0.96 | |
| 151_Y | 154_L | 1.091 | 0.96 | |
| 89_D | 95_I | 1.086 | 0.96 | |
| 26_E | 97_R | 1.086 | 0.96 | |
| 123_I | 153_G | 1.082 | 0.96 | |
| 133_F | 137_F | 1.08 | 0.95 | |
| 26_E | 100_R | 1.07 | 0.95 | |
| 87_A | 98_C | 1.066 | 0.95 | |
| 68_G | 98_C | 1.059 | 0.95 | |
| 46_I | 132_N | 1.054 | 0.95 | |
| 47_G | 77_N | 1.053 | 0.95 | |
| 69_A | 73_S | 1.045 | 0.94 | |
| 137_F | 206_M | 1.024 | 0.93 | |
| 22_E | 91_S | 1.021 | 0.93 | |
| 136_Q | 206_M | 1.02 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4gekA | 2 | 1 | 100 | 0.325 | Contact Map | 0.781 |
| 3dtnA | 2 | 0.9271 | 100 | 0.429 | Contact Map | 0.807 |
| 3bxoA | 2 | 0.8745 | 100 | 0.46 | Contact Map | 0.797 |
| 1y8cA | 1 | 0.8826 | 100 | 0.47 | Contact Map | 0.766 |
| 3pfgA | 1 | 0.9312 | 100 | 0.48 | Contact Map | 0.82 |
| 1wznA | 3 | 0.8745 | 100 | 0.492 | Contact Map | 0.824 |
| 4htfA | 1 | 0.9312 | 99.9 | 0.497 | Contact Map | 0.723 |
| 4hgzA | 6 | 0.9636 | 99.9 | 0.497 | Contact Map | 0.835 |
| 3hnrA | 1 | 0.8664 | 99.9 | 0.499 | Contact Map | 0.736 |
| 2o57A | 4 | 0.8907 | 99.9 | 0.5 | Contact Map | 0.793 |
Sequence Conservation (Image Generated using WebLogo v3)