| UniProt: | P17993 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11143 | ||
| Length: | 240 (229) | ||
| Sequences: | 4313 | ||
| Seq/Len: | 18.83 |
| UBIG
Paralog alert: 0.71 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: BIOC CMOA SMTA TAM TEHB UBIE UBIG YAFE YJHP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 59_K | 80_T | 3.125 | 1.00 | |
| 84_L | 110_E | 3.005 | 1.00 | |
| 88_F | 109_Q | 2.912 | 1.00 | |
| 21_E | 87_G | 2.9 | 1.00 | |
| 146_A | 206_L | 2.824 | 1.00 | |
| 193_K | 196_E | 2.785 | 1.00 | |
| 139_Q | 203_Q | 2.736 | 1.00 | |
| 117_A | 123_Y | 2.583 | 1.00 | |
| 64_G | 131_M | 2.579 | 1.00 | |
| 93_V | 96_L | 2.543 | 1.00 | |
| 144_A | 147_Q | 2.512 | 1.00 | |
| 63_V | 145_C | 2.436 | 1.00 | |
| 21_E | 89_E | 2.417 | 1.00 | |
| 88_F | 92_Q | 2.355 | 1.00 | |
| 61_L | 123_Y | 2.34 | 1.00 | |
| 138_P | 200_W | 2.314 | 1.00 | |
| 82_T | 123_Y | 2.307 | 1.00 | |
| 80_T | 106_D | 2.245 | 1.00 | |
| 124_D | 150_K | 2.238 | 1.00 | |
| 194_P | 213_G | 2.21 | 1.00 | |
| 149_V | 155_V | 2.141 | 1.00 | |
| 65_C | 83_G | 2.095 | 1.00 | |
| 137_D | 140_S | 2.091 | 1.00 | |
| 111_T | 114_E | 2.066 | 1.00 | |
| 198_L | 202_D | 2.053 | 1.00 | |
| 91_L | 109_Q | 1.997 | 1.00 | |
| 92_Q | 95_K | 1.915 | 1.00 | |
| 84_L | 108_V | 1.894 | 1.00 | |
| 60_V | 74_M | 1.885 | 1.00 | |
| 149_V | 153_G | 1.881 | 1.00 | |
| 145_C | 155_V | 1.824 | 1.00 | |
| 126_V | 145_C | 1.817 | 1.00 | |
| 126_V | 149_V | 1.808 | 1.00 | |
| 139_Q | 143_R | 1.744 | 1.00 | |
| 135_V | 141_V | 1.743 | 1.00 | |
| 144_A | 148_L | 1.67 | 1.00 | |
| 65_C | 71_A | 1.635 | 1.00 | |
| 110_E | 116_A | 1.635 | 1.00 | |
| 149_V | 206_L | 1.631 | 1.00 | |
| 140_S | 143_R | 1.624 | 1.00 | |
| 155_V | 201_V | 1.61 | 1.00 | |
| 71_A | 81_V | 1.608 | 1.00 | |
| 49_A | 77_E | 1.608 | 1.00 | |
| 60_V | 81_V | 1.594 | 1.00 | |
| 59_K | 82_T | 1.564 | 1.00 | |
| 120_A | 147_Q | 1.552 | 1.00 | |
| 82_T | 108_V | 1.549 | 1.00 | |
| 199_G | 202_D | 1.523 | 1.00 | |
| 86_M | 111_T | 1.512 | 1.00 | |
| 83_G | 107_Y | 1.471 | 1.00 | |
| 139_Q | 200_W | 1.43 | 1.00 | |
| 59_K | 123_Y | 1.404 | 0.99 | |
| 132_L | 197_L | 1.391 | 0.99 | |
| 60_V | 125_V | 1.384 | 0.99 | |
| 67_G | 97_H | 1.358 | 0.99 | |
| 55_L | 58_K | 1.346 | 0.99 | |
| 143_R | 203_Q | 1.342 | 0.99 | |
| 71_A | 83_G | 1.322 | 0.99 | |
| 68_G | 94_A | 1.316 | 0.99 | |
| 59_K | 150_K | 1.31 | 0.99 | |
| 72_E | 97_H | 1.295 | 0.99 | |
| 196_E | 199_G | 1.293 | 0.99 | |
| 63_V | 112_V | 1.287 | 0.99 | |
| 201_V | 237_T | 1.271 | 0.99 | |
| 94_A | 107_Y | 1.26 | 0.99 | |
| 128_C | 135_V | 1.254 | 0.99 | |
| 133_E | 159_T | 1.244 | 0.98 | |
| 108_V | 118_K | 1.216 | 0.98 | |
| 115_H | 148_L | 1.215 | 0.98 | |
| 61_L | 148_L | 1.208 | 0.98 | |
| 199_G | 203_Q | 1.194 | 0.98 | |
| 118_K | 122_Q | 1.191 | 0.98 | |
| 154_D | 236_H | 1.181 | 0.98 | |
| 198_L | 211_I | 1.181 | 0.98 | |
| 98_A | 107_Y | 1.179 | 0.98 | |
| 139_Q | 204_T | 1.172 | 0.98 | |
| 26_R | 30_L | 1.166 | 0.97 | |
| 51_R | 212_T | 1.164 | 0.97 | |
| 82_T | 106_D | 1.156 | 0.97 | |
| 96_L | 100_E | 1.14 | 0.97 | |
| 61_L | 126_V | 1.14 | 0.97 | |
| 217_N | 220_T | 1.138 | 0.97 | |
| 64_G | 135_V | 1.128 | 0.97 | |
| 175_E | 179_R | 1.123 | 0.97 | |
| 52_A | 125_V | 1.12 | 0.96 | |
| 128_C | 131_M | 1.119 | 0.96 | |
| 64_G | 128_C | 1.116 | 0.96 | |
| 114_E | 140_S | 1.116 | 0.96 | |
| 91_L | 94_A | 1.113 | 0.96 | |
| 29_D | 97_H | 1.111 | 0.96 | |
| 117_A | 148_L | 1.102 | 0.96 | |
| 72_E | 98_A | 1.076 | 0.95 | |
| 91_L | 107_Y | 1.076 | 0.95 | |
| 68_G | 107_Y | 1.065 | 0.95 | |
| 130_E | 134_H | 1.057 | 0.95 | |
| 214_L | 234_M | 1.057 | 0.95 | |
| 67_G | 90_P | 1.05 | 0.94 | |
| 117_A | 147_Q | 1.039 | 0.94 | |
| 63_V | 84_L | 1.038 | 0.94 | |
| 143_R | 204_T | 1.035 | 0.94 | |
| 12_V | 17_I | 1.035 | 0.94 | |
| 46_G | 50_E | 1.024 | 0.93 | |
| 59_K | 122_Q | 1.017 | 0.93 | |
| 83_G | 94_A | 1.016 | 0.93 | |
| 130_E | 133_E | 1.009 | 0.93 | |
| 117_A | 144_A | 1.005 | 0.93 | |
| 21_E | 88_F | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3bkwA | 2 | 0.9208 | 100 | 0.469 | Contact Map | 0.825 |
| 2p7iA | 2 | 0.9083 | 100 | 0.472 | Contact Map | 0.776 |
| 3l8dA | 1 | 0.9167 | 100 | 0.476 | Contact Map | 0.782 |
| 3g5lA | 2 | 0.9292 | 100 | 0.476 | Contact Map | 0.85 |
| 1vl5A | 4 | 0.8958 | 100 | 0.483 | Contact Map | 0.818 |
| 2yqzA | 2 | 0.9083 | 100 | 0.484 | Contact Map | 0.717 |
| 3e8sA | 1 | 0.9167 | 100 | 0.487 | Contact Map | 0.743 |
| 1y8cA | 1 | 0.8708 | 100 | 0.487 | Contact Map | 0.741 |
| 4htfA | 1 | 0.9792 | 100 | 0.489 | Contact Map | 0.731 |
| 2o57A | 4 | 0.9625 | 100 | 0.491 | Contact Map | 0.785 |
Sequence Conservation (Image Generated using WebLogo v3)