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YJHP - Uncharacterized protein YjhP
UniProt: P39367 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12558
Length: 248 (235)
Sequences: 2259
Seq/Len: 9.61

YJHP
Paralog alert: 0.20 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: BIOC CMOA SMTA TAM TEHB UBIE UBIG YAFE YJHP
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
181_V 246_I 4.973 1.00
171_V 175_D 3.41 1.00
40_I 54_W 3.236 1.00
120_A 176_D 2.971 1.00
127_A 179_Y 2.859 1.00
126_L 136_M 2.744 1.00
172_G 176_D 2.539 1.00
174_F 245_L 2.5 1.00
39_R 61_T 2.494 1.00
61_T 89_H 2.491 1.00
125_L 128_Q 2.442 1.00
43_L 95_A 2.408 1.00
51_L 62_G 2.385 1.00
109_C 122_A 2.261 1.00
99_V 104_C 2.247 1.00
101_N 128_Q 2.24 1.00
183_E 244_A 2.124 1.00
172_G 175_D 2.115 1.00
65_I 95_A 2.102 1.00
130_L 136_M 2.102 1.00
180_D 246_I 2.023 1.00
123_E 138_I 2.018 1.00
55_A 88_V 2.01 1.00
171_V 184_M 1.992 1.00
116_A 122_A 1.937 1.00
213_D 217_A 1.931 1.00
208_E 216_A 1.917 1.00
95_A 116_A 1.903 1.00
105_D 131_K 1.876 1.00
56_R 82_L 1.857 1.00
64_G 75_A 1.826 1.00
109_C 112_A 1.759 1.00
65_I 93_N 1.759 1.00
130_L 134_G 1.753 1.00
121_G 125_L 1.742 1.00
38_T 59_G 1.722 1.00
120_A 173_A 1.707 1.00
125_L 129_S 1.699 1.00
42_D 46_G 1.675 1.00
100_A 103_K 1.647 1.00
135_I 246_I 1.642 1.00
22_E 26_A 1.642 1.00
45_S 51_L 1.629 1.00
41_L 104_C 1.616 1.00
117_G 162_S 1.604 1.00
118_G 121_G 1.59 1.00
229_R 232_T 1.587 1.00
155_A 222_E 1.574 1.00
138_I 174_F 1.55 1.00
107_A 130_L 1.548 1.00
120_A 124_E 1.518 1.00
63_T 91_I 1.507 1.00
107_A 129_S 1.501 1.00
146_L 235_R 1.495 1.00
184_M 241_G 1.49 1.00
204_R 217_A 1.482 1.00
64_G 90_F 1.458 1.00
130_L 179_Y 1.425 1.00
226_A 229_R 1.421 0.99
140_E 170_L 1.367 0.99
69_S 92_H 1.362 0.99
91_I 99_V 1.354 0.99
44_G 109_C 1.349 0.99
120_A 177_L 1.344 0.99
79_A 90_F 1.343 0.99
135_I 181_V 1.34 0.99
126_L 130_L 1.318 0.99
39_R 103_K 1.314 0.99
218_E 221_A 1.304 0.99
103_K 129_S 1.266 0.99
136_M 174_F 1.251 0.98
48_G 90_F 1.21 0.98
44_G 48_G 1.204 0.98
38_T 131_K 1.203 0.98
47_S 70_L 1.198 0.98
103_K 128_Q 1.197 0.98
142_Y 241_G 1.188 0.98
20_F 25_Y 1.186 0.98
44_G 112_A 1.167 0.97
52_C 79_A 1.166 0.97
212_D 215_F 1.156 0.97
72_T 92_H 1.135 0.97
68_S 71_F 1.13 0.96
109_C 138_I 1.129 0.96
65_I 91_I 1.122 0.96
211_P 219_V 1.116 0.96
202_T 205_R 1.109 0.96
123_E 170_L 1.1 0.96
207_L 220_R 1.084 0.95
218_E 222_E 1.083 0.95
63_T 104_C 1.07 0.95
175_D 182_V 1.066 0.95
245_L 248_R 1.061 0.94
174_F 243_F 1.056 0.94
222_E 225_I 1.043 0.94
75_A 90_F 1.042 0.94
69_S 73_A 1.035 0.93
218_E 224_N 1.034 0.93
109_C 136_M 1.014 0.93
112_A 116_A 1.01 0.92
55_A 62_G 1.006 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1nkvA311000.323Contact Map0.561
3f4kA10.98791000.328Contact Map0.596
3kkzA20.98391000.36Contact Map0.64
2o57A40.97981000.399Contact Map0.657
4kriA30.97581000.412Contact Map0.707
3ujcA10.96771000.413Contact Map0.679
3busA20.96771000.428Contact Map0.665
3vc1A120.91941000.46Contact Map0.73
2yqzA20.97581000.464Contact Map0.613
1xxlA20.89521000.475Contact Map0.673

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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