| UniProt: | P76145 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13812 | ||
| Length: | 252 (247) | ||
| Sequences: | 4220 | ||
| Seq/Len: | 17.09 |
| TAM
Paralog alert: 0.61 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: BIOC CMOA SMTA TAM TEHB UBIE UBIG YAFE YJHP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 175_E | 249_R | 4.005 | 1.00 | |
| 34_Y | 57_R | 3.518 | 1.00 | |
| 90_P | 94_L | 3.024 | 1.00 | |
| 95_D | 121_N | 2.895 | 1.00 | |
| 116_L | 126_L | 2.798 | 1.00 | |
| 57_R | 79_Q | 2.781 | 1.00 | |
| 166_Y | 170_S | 2.61 | 1.00 | |
| 36_A | 94_L | 2.57 | 1.00 | |
| 115_H | 118_S | 2.568 | 1.00 | |
| 110_Y | 171_E | 2.439 | 1.00 | |
| 120_L | 126_L | 2.397 | 1.00 | |
| 68_I | 82_E | 2.363 | 1.00 | |
| 108_D | 111_E | 2.353 | 1.00 | |
| 210_T | 213_E | 2.237 | 1.00 | |
| 40_C | 60_G | 2.217 | 1.00 | |
| 120_L | 124_G | 2.199 | 1.00 | |
| 117_V | 174_C | 2.104 | 1.00 | |
| 169_L | 248_A | 2.057 | 1.00 | |
| 35_V | 49_L | 2.05 | 1.00 | |
| 85_I | 106_L | 1.994 | 1.00 | |
| 97_I | 116_L | 1.97 | 1.00 | |
| 125_V | 249_R | 1.949 | 1.00 | |
| 115_H | 119_L | 1.916 | 1.00 | |
| 117_V | 250_R | 1.916 | 1.00 | |
| 38_L | 85_I | 1.905 | 1.00 | |
| 59_T | 94_L | 1.873 | 1.00 | |
| 50_Q | 78_C | 1.866 | 1.00 | |
| 203_R | 207_Q | 1.824 | 1.00 | |
| 97_I | 120_L | 1.802 | 1.00 | |
| 65_P | 82_E | 1.762 | 1.00 | |
| 46_T | 58_I | 1.757 | 1.00 | |
| 106_L | 112_L | 1.754 | 1.00 | |
| 99_A | 102_S | 1.747 | 1.00 | |
| 34_Y | 59_T | 1.703 | 1.00 | |
| 167_D | 170_S | 1.701 | 1.00 | |
| 65_P | 69_A | 1.676 | 1.00 | |
| 60_G | 80_F | 1.642 | 1.00 | |
| 53_W | 56_A | 1.631 | 1.00 | |
| 167_D | 171_E | 1.628 | 1.00 | |
| 110_Y | 168_I | 1.617 | 1.00 | |
| 61_I | 83_A | 1.614 | 1.00 | |
| 10_L | 42_P | 1.6 | 1.00 | |
| 177_D | 247_V | 1.595 | 1.00 | |
| 91_V | 118_S | 1.524 | 1.00 | |
| 37_D | 60_G | 1.511 | 1.00 | |
| 71_A | 80_F | 1.497 | 1.00 | |
| 39_G | 102_S | 1.49 | 1.00 | |
| 25_A | 52_R | 1.481 | 1.00 | |
| 39_G | 99_A | 1.475 | 1.00 | |
| 35_V | 96_L | 1.473 | 1.00 | |
| 40_C | 46_T | 1.448 | 1.00 | |
| 113_F | 128_V | 1.423 | 1.00 | |
| 116_L | 120_L | 1.402 | 0.99 | |
| 60_G | 71_A | 1.401 | 0.99 | |
| 101_A | 131_P | 1.392 | 0.99 | |
| 132_D | 244_L | 1.392 | 0.99 | |
| 191_Q | 222_H | 1.39 | 0.99 | |
| 128_V | 246_I | 1.386 | 0.99 | |
| 120_L | 174_C | 1.373 | 0.99 | |
| 62_D | 68_I | 1.373 | 0.99 | |
| 100_N | 129_Q | 1.364 | 0.99 | |
| 68_I | 80_F | 1.358 | 0.99 | |
| 126_L | 248_A | 1.356 | 0.99 | |
| 34_Y | 93_A | 1.343 | 0.99 | |
| 220_R | 223_Q | 1.342 | 0.99 | |
| 111_E | 115_H | 1.331 | 0.99 | |
| 37_D | 41_G | 1.318 | 0.99 | |
| 22_E | 25_A | 1.288 | 0.99 | |
| 189_S | 192_A | 1.278 | 0.99 | |
| 88_W | 119_L | 1.275 | 0.99 | |
| 110_Y | 114_P | 1.273 | 0.99 | |
| 83_A | 89_Q | 1.258 | 0.99 | |
| 40_C | 71_A | 1.253 | 0.99 | |
| 166_Y | 178_I | 1.244 | 0.98 | |
| 211_E | 215_Q | 1.24 | 0.98 | |
| 32_V | 35_V | 1.239 | 0.98 | |
| 219_K | 223_Q | 1.235 | 0.98 | |
| 93_A | 119_L | 1.233 | 0.98 | |
| 126_L | 169_L | 1.229 | 0.98 | |
| 93_A | 121_N | 1.227 | 0.98 | |
| 86_R | 107_P | 1.209 | 0.98 | |
| 97_I | 119_L | 1.205 | 0.98 | |
| 88_W | 115_H | 1.2 | 0.98 | |
| 89_Q | 115_H | 1.195 | 0.98 | |
| 70_E | 73_S | 1.193 | 0.98 | |
| 37_D | 40_C | 1.191 | 0.98 | |
| 218_L | 222_H | 1.184 | 0.98 | |
| 34_Y | 121_N | 1.181 | 0.98 | |
| 34_Y | 94_L | 1.177 | 0.98 | |
| 37_D | 43_G | 1.169 | 0.97 | |
| 33_E | 125_V | 1.165 | 0.97 | |
| 99_A | 112_L | 1.165 | 0.97 | |
| 99_A | 128_V | 1.164 | 0.97 | |
| 59_T | 81_V | 1.155 | 0.97 | |
| 216_L | 219_K | 1.155 | 0.97 | |
| 19_P | 100_N | 1.151 | 0.97 | |
| 61_I | 85_I | 1.133 | 0.97 | |
| 180_R | 242_P | 1.13 | 0.97 | |
| 216_L | 220_R | 1.127 | 0.97 | |
| 22_E | 26_R | 1.113 | 0.96 | |
| 102_S | 106_L | 1.108 | 0.96 | |
| 38_L | 116_L | 1.092 | 0.96 | |
| 182_T | 242_P | 1.092 | 0.96 | |
| 180_R | 244_L | 1.09 | 0.96 | |
| 181_T | 245_F | 1.085 | 0.96 | |
| 129_Q | 243_R | 1.08 | 0.95 | |
| 209_L | 217_F | 1.076 | 0.95 | |
| 213_E | 216_L | 1.069 | 0.95 | |
| 206_L | 214_Q | 1.06 | 0.95 | |
| 20_A | 45_S | 1.06 | 0.95 | |
| 81_V | 90_P | 1.059 | 0.95 | |
| 18_R | 22_E | 1.056 | 0.95 | |
| 45_S | 98_F | 1.051 | 0.94 | |
| 33_E | 56_A | 1.048 | 0.94 | |
| 137_P | 140_V | 1.047 | 0.94 | |
| 127_A | 247_V | 1.044 | 0.94 | |
| 16_R | 19_P | 1.042 | 0.94 | |
| 46_T | 60_G | 1.041 | 0.94 | |
| 33_E | 121_N | 1.036 | 0.94 | |
| 10_L | 74_A | 1.034 | 0.94 | |
| 61_I | 81_V | 1.034 | 0.94 | |
| 47_A | 74_A | 1.024 | 0.93 | |
| 178_I | 244_L | 1.023 | 0.93 | |
| 215_Q | 219_K | 1.022 | 0.93 | |
| 94_L | 97_I | 1.02 | 0.93 | |
| 13_S | 16_R | 1.016 | 0.93 | |
| 101_A | 243_R | 1.011 | 0.93 | |
| 110_Y | 172_A | 1.009 | 0.93 | |
| 33_E | 55_A | 1.009 | 0.93 | |
| 12_F | 199_A | 1.007 | 0.93 | |
| 92_Q | 250_R | 1.004 | 0.93 | |
| 10_L | 44_N | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2p35A | 2 | 0.996 | 100 | 0.27 | Contact Map | 0.643 |
| 3ccfA | 2 | 0.9762 | 100 | 0.337 | Contact Map | 0.697 |
| 2yqzA | 2 | 0.9683 | 100 | 0.395 | Contact Map | 0.715 |
| 4hg2A | 2 | 0.9405 | 100 | 0.434 | Contact Map | 0.597 |
| 3egeA | 1 | 0.9563 | 100 | 0.434 | Contact Map | 0.704 |
| 1vl5A | 4 | 0.9444 | 100 | 0.438 | Contact Map | 0.792 |
| 3b5iA | 2 | 0.9762 | 100 | 0.439 | Contact Map | 0.606 |
| 1m6eX | 1 | 0.9762 | 100 | 0.44 | Contact Map | 0.575 |
| 3g5tA | 1 | 0.9484 | 100 | 0.444 | Contact Map | 0.673 |
| 1xxlA | 2 | 0.9087 | 100 | 0.463 | Contact Map | 0.742 |
Sequence Conservation (Image Generated using WebLogo v3)