| UniProt: | P25397 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11884 | ||
| Length: | 197 (187) | ||
| Sequences: | 3398 | ||
| Seq/Len: | 18.17 |
| TEHB
Paralog alert: 0.63 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: BIOC CMOA SMTA TAM TEHB UBIE UBIG YAFE YJHP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 65_I | 84_V | 3.443 | 1.00 | |
| 119_N | 122_R | 3.356 | 1.00 | |
| 33_K | 54_D | 3.232 | 1.00 | |
| 97_D | 125_K | 3.087 | 1.00 | |
| 124_T | 128_G | 2.976 | 1.00 | |
| 68_V | 82_T | 2.885 | 1.00 | |
| 121_Q | 163_W | 2.741 | 1.00 | |
| 65_I | 82_T | 2.712 | 1.00 | |
| 56_D | 96_Y | 2.692 | 1.00 | |
| 62_A | 84_V | 2.578 | 1.00 | |
| 50_A | 75_E | 2.515 | 1.00 | |
| 120_M | 130_N | 2.503 | 1.00 | |
| 35_L | 96_Y | 2.462 | 1.00 | |
| 62_A | 66_A | 2.262 | 1.00 | |
| 34_T | 98_F | 2.257 | 1.00 | |
| 39_C | 57_A | 2.252 | 1.00 | |
| 33_K | 97_D | 2.133 | 1.00 | |
| 56_D | 83_R | 2.124 | 1.00 | |
| 86_D | 89_N | 2.124 | 1.00 | |
| 45_S | 57_A | 2.047 | 1.00 | |
| 119_N | 123_C | 1.925 | 1.00 | |
| 63_M | 66_A | 1.889 | 1.00 | |
| 37_L | 87_L | 1.869 | 1.00 | |
| 37_L | 120_M | 1.823 | 1.00 | |
| 61_N | 64_S | 1.788 | 1.00 | |
| 124_T | 130_N | 1.779 | 1.00 | |
| 57_A | 68_V | 1.752 | 1.00 | |
| 54_D | 81_H | 1.724 | 1.00 | |
| 92_F | 96_Y | 1.695 | 1.00 | |
| 46_L | 71_I | 1.691 | 1.00 | |
| 99_I | 123_C | 1.591 | 1.00 | |
| 35_L | 99_I | 1.55 | 1.00 | |
| 45_S | 55_V | 1.545 | 1.00 | |
| 41_N | 71_I | 1.498 | 1.00 | |
| 56_D | 81_H | 1.495 | 1.00 | |
| 36_D | 57_A | 1.486 | 1.00 | |
| 153_E | 157_R | 1.46 | 1.00 | |
| 124_T | 163_W | 1.429 | 1.00 | |
| 33_K | 95_Q | 1.423 | 1.00 | |
| 66_A | 69_E | 1.422 | 1.00 | |
| 72_K | 82_T | 1.366 | 0.99 | |
| 157_R | 161_E | 1.344 | 0.99 | |
| 10_T | 63_M | 1.343 | 0.99 | |
| 85_V | 90_L | 1.341 | 0.99 | |
| 99_I | 124_T | 1.336 | 0.99 | |
| 39_C | 59_D | 1.332 | 0.99 | |
| 38_G | 104_V | 1.323 | 0.99 | |
| 90_L | 96_Y | 1.318 | 0.99 | |
| 33_K | 125_K | 1.289 | 0.99 | |
| 129_Y | 166_V | 1.278 | 0.99 | |
| 117_I | 160_Y | 1.267 | 0.99 | |
| 60_K | 86_D | 1.256 | 0.99 | |
| 46_L | 72_K | 1.254 | 0.99 | |
| 164_E | 195_R | 1.253 | 0.99 | |
| 103_V | 106_M | 1.252 | 0.99 | |
| 41_N | 64_S | 1.247 | 0.99 | |
| 39_C | 68_V | 1.233 | 0.98 | |
| 38_G | 108_L | 1.225 | 0.98 | |
| 46_L | 77_L | 1.185 | 0.98 | |
| 153_E | 170_E | 1.181 | 0.98 | |
| 41_N | 67_N | 1.179 | 0.98 | |
| 45_S | 80_L | 1.171 | 0.98 | |
| 118_A | 122_R | 1.151 | 0.97 | |
| 65_I | 69_E | 1.136 | 0.97 | |
| 33_K | 56_D | 1.131 | 0.97 | |
| 59_D | 65_I | 1.13 | 0.97 | |
| 91_T | 119_N | 1.123 | 0.97 | |
| 165_R | 168_Y | 1.123 | 0.97 | |
| 113_I | 159_Y | 1.105 | 0.96 | |
| 58_W | 85_V | 1.103 | 0.96 | |
| 47_Y | 51_N | 1.092 | 0.96 | |
| 101_S | 106_M | 1.084 | 0.96 | |
| 90_L | 123_C | 1.084 | 0.96 | |
| 38_G | 101_S | 1.079 | 0.95 | |
| 9_F | 12_K | 1.072 | 0.95 | |
| 47_Y | 50_A | 1.066 | 0.95 | |
| 58_W | 83_R | 1.062 | 0.95 | |
| 67_N | 70_R | 1.043 | 0.94 | |
| 70_R | 73_S | 1.042 | 0.94 | |
| 83_R | 93_D | 1.042 | 0.94 | |
| 103_V | 135_A | 1.042 | 0.94 | |
| 121_Q | 196_K | 1.04 | 0.94 | |
| 157_R | 168_Y | 1.033 | 0.94 | |
| 7_N | 12_K | 1.033 | 0.94 | |
| 32_G | 98_F | 1.025 | 0.93 | |
| 36_D | 39_C | 1.005 | 0.93 | |
| 27_K | 51_N | 1.002 | 0.92 | |
| 69_E | 81_H | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2xvmA | 2 | 1 | 100 | 0.274 | Contact Map | 0.8 |
| 3m70A | 1 | 0.9949 | 100 | 0.308 | Contact Map | 0.766 |
| 2kw5A | 1 | 0.9188 | 99.9 | 0.373 | Contact Map | 0.545 |
| 2gb4A | 2 | 0.9848 | 99.9 | 0.383 | Contact Map | 0.779 |
| 3sm3A | 1 | 0.9543 | 99.9 | 0.384 | Contact Map | 0.746 |
| 3lccA | 1 | 0.9391 | 99.9 | 0.394 | Contact Map | 0.774 |
| 1y8cA | 1 | 0.934 | 99.9 | 0.407 | Contact Map | 0.753 |
| 1wznA | 3 | 0.9594 | 99.9 | 0.408 | Contact Map | 0.794 |
| 3ggdA | 1 | 0.9797 | 99.9 | 0.41 | Contact Map | 0.665 |
| 3e23A | 1 | 0.9391 | 99.9 | 0.412 | Contact Map | 0.759 |
Sequence Conservation (Image Generated using WebLogo v3)