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OPENSEQ.org
YNJB - Protein YnjB
UniProt: P76223 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14004
Length: 388 (353)
Sequences: 2724
Seq/Len: 7.72
YNJB
Paralog alert: 0.69 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: CYSP MALE MODA POTD POTF SUBI THIB UGPB YCJN YDCS YNJB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
174_E 178_A 5.654 1.00
159_R 286_Y 3.857 1.00
114_Q 310_S 3.772 1.00
160_D 284_S 3.72 1.00
55_G 59_T 3.604 1.00
61_Y 315_V 3.518 1.00
56_E 319_F 3.315 1.00
58_K 64_N 3.065 1.00
36_W 66_K 3.006 1.00
63_I 312_A 2.971 1.00
229_Q 233_V 2.9 1.00
319_F 325_A 2.594 1.00
60_H 322_S 2.561 1.00
348_D 351_R 2.56 1.00
34_T 66_K 2.553 1.00
34_T 64_N 2.394 1.00
58_K 61_Y 2.39 1.00
56_E 328_R 2.377 1.00
116_G 143_G 2.307 1.00
322_S 325_A 2.272 1.00
96_L 317_A 2.231 1.00
57_M 63_I 2.215 1.00
167_Q 291_R 2.21 1.00
316_V 320_L 2.197 1.00
323_P 327_L 2.186 1.00
51_D 55_G 2.163 1.00
57_M 315_V 2.162 1.00
56_E 59_T 2.147 1.00
170_Q 174_E 2.127 1.00
310_S 314_K 2.104 1.00
107_L 113_L 2.1 1.00
380_E 384_R 2.074 1.00
158_R 161_V 2.07 1.00
63_I 315_V 2.013 1.00
348_D 352_E 2.005 1.00
311_A 315_V 2.002 1.00
55_G 58_K 2.001 1.00
37_F 96_L 1.963 1.00
154_T 287_S 1.96 1.00
358_M 361_D 1.959 1.00
157_A 286_Y 1.959 1.00
328_R 331_D 1.954 1.00
225_A 229_Q 1.953 1.00
373_W 376_A 1.909 1.00
52_W 55_G 1.881 1.00
111_N 305_A 1.877 1.00
315_V 318_N 1.866 1.00
307_A 310_S 1.845 1.00
173_L 233_V 1.842 1.00
145_E 300_F 1.81 1.00
35_V 312_A 1.772 1.00
113_L 302_T 1.766 1.00
168_T 292_E 1.761 1.00
228_W 380_E 1.729 1.00
301_V 317_A 1.7 1.00
309_A 312_A 1.692 1.00
226_P 229_Q 1.688 1.00
182_T 262_R 1.621 1.00
171_A 174_E 1.62 1.00
312_A 315_V 1.616 1.00
120_T 311_A 1.6 1.00
230_Y 233_V 1.595 1.00
232_D 236_P 1.589 1.00
159_R 284_S 1.588 1.00
379_Q 383_H 1.544 1.00
60_H 324_D 1.538 1.00
225_A 380_E 1.524 1.00
81_Q 110_A 1.514 1.00
301_V 320_L 1.501 0.99
56_E 60_H 1.481 0.99
35_V 316_V 1.481 0.99
116_G 144_A 1.481 0.99
229_Q 232_D 1.479 0.99
151_A 297_N 1.474 0.99
54_S 65_L 1.474 0.99
230_Y 234_L 1.46 0.99
184_T 261_L 1.455 0.99
33_Q 312_A 1.443 0.99
168_T 171_A 1.437 0.99
303_I 314_K 1.434 0.99
57_M 316_V 1.427 0.99
54_S 58_K 1.411 0.99
303_I 310_S 1.389 0.99
327_L 331_D 1.388 0.99
33_Q 309_A 1.386 0.99
77_V 107_L 1.375 0.99
122_P 318_N 1.362 0.99
233_V 236_P 1.359 0.99
324_D 328_R 1.351 0.99
114_Q 307_A 1.317 0.98
116_G 142_Q 1.315 0.98
108_K 144_A 1.307 0.98
114_Q 305_A 1.303 0.98
126_Y 343_P 1.299 0.98
71_A 75_D 1.29 0.98
123_N 126_Y 1.288 0.98
161_V 262_R 1.279 0.98
117_W 121_L 1.276 0.98
162_T 263_L 1.269 0.98
269_P 337_D 1.265 0.98
52_W 56_E 1.26 0.98
57_M 61_Y 1.256 0.98
59_T 163_P 1.244 0.97
370_H 373_W 1.242 0.97
65_L 316_V 1.241 0.97
149_G 299_H 1.233 0.97
166_P 171_A 1.231 0.97
35_V 65_L 1.229 0.97
376_A 380_E 1.227 0.97
303_I 317_A 1.225 0.97
369_P 372_G 1.223 0.97
216_D 219_T 1.222 0.97
157_A 165_P 1.216 0.97
167_Q 171_A 1.208 0.97
369_P 373_W 1.204 0.97
120_T 314_K 1.2 0.96
349_G 352_E 1.199 0.96
122_P 125_R 1.167 0.96
72_D 75_D 1.166 0.96
32_G 64_N 1.163 0.96
95_D 309_A 1.159 0.95
79_R 83_E 1.159 0.95
123_N 318_N 1.154 0.95
38_N 94_V 1.149 0.95
204_L 230_Y 1.148 0.95
207_D 210_A 1.147 0.95
176_A 237_Y 1.145 0.95
146_S 317_A 1.141 0.95
104_F 145_E 1.14 0.95
303_I 313_A 1.129 0.95
91_G 308_N 1.121 0.94
166_P 263_L 1.119 0.94
379_Q 382_L 1.117 0.94
326_Q 339_S 1.108 0.94
158_R 284_S 1.108 0.94
38_N 83_E 1.1 0.94
157_A 288_F 1.093 0.93
256_L 285_S 1.085 0.93
219_T 226_P 1.084 0.93
232_D 384_R 1.083 0.93
96_L 313_A 1.081 0.93
177_K 237_Y 1.077 0.93
360_Q 363_P 1.075 0.93
54_S 316_V 1.074 0.92
95_D 307_A 1.074 0.92
366_L 369_P 1.067 0.92
375_N 379_Q 1.063 0.92
56_E 324_D 1.061 0.92
54_S 64_N 1.056 0.92
311_A 314_K 1.055 0.92
114_Q 314_K 1.052 0.91
168_T 291_R 1.04 0.91
159_R 163_P 1.031 0.90
156_I 256_L 1.026 0.90
58_K 62_A 1.025 0.90
206_P 219_T 1.024 0.90
359_P 363_P 1.023 0.90
173_L 234_L 1.023 0.90
62_A 315_V 1.023 0.90
174_E 177_K 1.02 0.90
359_P 362_L 1.016 0.89
380_E 383_H 1.002 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4edpA20.87891000.416Contact Map0.744
3uorA20.92011000.422Contact Map0.706
3rpwA10.8661000.426Contact Map0.707
4eqbA20.82991000.43Contact Map0.787
3pu5A10.82471000.43Contact Map0.677
4i1dA40.80931000.437Contact Map0.692
4gl0A10.83511000.439Contact Map0.783
4euoA10.80151000.441Contact Map0.723
2xd3A10.92011000.446Contact Map0.681
1potA10.8171000.451Contact Map0.774
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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