| UniProt: | P0AFK9 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10752 | ||
| Length: | 348 (321) | ||
| Sequences: | 10063 | ||
| Seq/Len: | 31.35 |
| POTD
Paralog alert: 0.84 [within 20: 0.19] - ratio of genomes with paralogs Cluster includes: CYSP MALE MODA POTD POTF SUBI THIB UGPB YCJN YDCS YNJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 97_Q | 268_K | 3.93 | 1.00 | |
| 140_G | 244_D | 3.816 | 1.00 | |
| 30_Y | 55_I | 3.447 | 1.00 | |
| 197_N | 201_K | 3.375 | 1.00 | |
| 28_T | 55_I | 3.284 | 1.00 | |
| 52_I | 270_G | 3.223 | 1.00 | |
| 141_D | 242_P | 3.129 | 1.00 | |
| 40_P | 44_E | 3.089 | 1.00 | |
| 50_T | 273_K | 3.071 | 1.00 | |
| 28_T | 53_K | 3.027 | 1.00 | |
| 45_Q | 277_F | 3.01 | 1.00 | |
| 47_T | 53_K | 2.969 | 1.00 | |
| 200_K | 204_P | 2.862 | 1.00 | |
| 109_N | 299_A | 2.851 | 1.00 | |
| 280_R | 283_V | 2.841 | 1.00 | |
| 138_V | 244_D | 2.781 | 1.00 | |
| 45_Q | 48_K | 2.65 | 1.00 | |
| 98_K | 123_N | 2.608 | 1.00 | |
| 155_W | 201_K | 2.586 | 1.00 | |
| 44_E | 48_K | 2.583 | 1.00 | |
| 41_G | 44_E | 2.537 | 1.00 | |
| 45_Q | 286_Q | 2.491 | 1.00 | |
| 46_F | 273_K | 2.482 | 1.00 | |
| 273_K | 276_N | 2.472 | 1.00 | |
| 190_K | 194_A | 2.344 | 1.00 | |
| 150_S | 153_D | 2.277 | 1.00 | |
| 267_N | 270_G | 2.264 | 1.00 | |
| 78_D | 267_N | 2.208 | 1.00 | |
| 143_V | 225_L | 2.133 | 1.00 | |
| 43_L | 274_L | 2.117 | 1.00 | |
| 96_I | 260_A | 2.09 | 1.00 | |
| 285_K | 289_E | 2.079 | 1.00 | |
| 49_E | 280_R | 2.058 | 1.00 | |
| 45_Q | 49_E | 2.041 | 1.00 | |
| 153_D | 156_K | 2.036 | 1.00 | |
| 194_A | 197_N | 2.019 | 1.00 | |
| 112_P | 116_N | 2.002 | 1.00 | |
| 126_S | 258_S | 1.992 | 1.00 | |
| 119_F | 124_D | 1.985 | 1.00 | |
| 46_F | 52_I | 1.981 | 1.00 | |
| 80_V | 262_P | 1.976 | 1.00 | |
| 47_T | 50_T | 1.929 | 1.00 | |
| 43_L | 47_T | 1.906 | 1.00 | |
| 140_G | 144_D | 1.896 | 1.00 | |
| 141_D | 145_P | 1.878 | 1.00 | |
| 44_E | 47_T | 1.863 | 1.00 | |
| 60_E | 64_T | 1.844 | 1.00 | |
| 142_A | 224_N | 1.817 | 1.00 | |
| 198_E | 201_K | 1.788 | 1.00 | |
| 269_E | 273_K | 1.763 | 1.00 | |
| 268_K | 272_L | 1.761 | 1.00 | |
| 201_K | 205_N | 1.749 | 1.00 | |
| 265_A | 268_K | 1.722 | 1.00 | |
| 97_Q | 263_A | 1.717 | 1.00 | |
| 79_L | 275_I | 1.703 | 1.00 | |
| 270_G | 273_K | 1.701 | 1.00 | |
| 100_D | 123_N | 1.681 | 1.00 | |
| 52_I | 273_K | 1.668 | 1.00 | |
| 306_P | 309_A | 1.661 | 1.00 | |
| 98_K | 124_D | 1.659 | 1.00 | |
| 261_I | 275_I | 1.657 | 1.00 | |
| 46_F | 277_F | 1.637 | 1.00 | |
| 193_E | 197_N | 1.625 | 1.00 | |
| 152_A | 155_W | 1.624 | 1.00 | |
| 277_F | 283_V | 1.614 | 1.00 | |
| 155_W | 202_L | 1.608 | 1.00 | |
| 306_P | 310_N | 1.602 | 1.00 | |
| 281_P | 285_K | 1.585 | 1.00 | |
| 94_G | 263_A | 1.579 | 1.00 | |
| 149_T | 153_D | 1.572 | 1.00 | |
| 43_L | 56_Y | 1.564 | 1.00 | |
| 148_V | 153_D | 1.556 | 1.00 | |
| 139_N | 142_A | 1.51 | 1.00 | |
| 32_Y | 72_Y | 1.508 | 1.00 | |
| 43_L | 54_V | 1.492 | 1.00 | |
| 68_K | 72_Y | 1.47 | 1.00 | |
| 41_G | 45_Q | 1.457 | 1.00 | |
| 79_L | 271_A | 1.457 | 1.00 | |
| 281_P | 297_N | 1.448 | 1.00 | |
| 46_F | 50_T | 1.446 | 1.00 | |
| 286_Q | 289_E | 1.424 | 1.00 | |
| 29_L | 270_G | 1.422 | 1.00 | |
| 118_P | 258_S | 1.417 | 1.00 | |
| 149_T | 249_K | 1.417 | 1.00 | |
| 138_V | 246_V | 1.413 | 1.00 | |
| 198_E | 202_L | 1.411 | 1.00 | |
| 146_K | 149_T | 1.411 | 1.00 | |
| 109_N | 297_N | 1.406 | 0.99 | |
| 286_Q | 290_T | 1.398 | 0.99 | |
| 46_F | 274_L | 1.398 | 0.99 | |
| 197_N | 200_K | 1.394 | 0.99 | |
| 54_V | 274_L | 1.386 | 0.99 | |
| 217_P | 222_E | 1.385 | 0.99 | |
| 274_L | 278_L | 1.364 | 0.99 | |
| 140_G | 242_P | 1.363 | 0.99 | |
| 91_R | 125_Y | 1.354 | 0.99 | |
| 155_W | 198_E | 1.352 | 0.99 | |
| 152_A | 156_K | 1.349 | 0.99 | |
| 116_N | 119_F | 1.348 | 0.99 | |
| 191_E | 194_A | 1.345 | 0.99 | |
| 102_S | 272_L | 1.344 | 0.99 | |
| 30_Y | 57_S | 1.337 | 0.99 | |
| 261_I | 272_L | 1.321 | 0.99 | |
| 33_N | 56_Y | 1.295 | 0.99 | |
| 201_K | 204_P | 1.291 | 0.99 | |
| 259_L | 275_I | 1.285 | 0.99 | |
| 269_E | 272_L | 1.285 | 0.99 | |
| 46_F | 270_G | 1.28 | 0.99 | |
| 70_K | 93_E | 1.275 | 0.99 | |
| 210_N | 213_N | 1.275 | 0.99 | |
| 261_I | 271_A | 1.269 | 0.99 | |
| 106_N | 276_N | 1.267 | 0.99 | |
| 78_D | 265_A | 1.26 | 0.99 | |
| 135_A | 245_V | 1.259 | 0.99 | |
| 111_D | 298_L | 1.252 | 0.99 | |
| 27_N | 270_G | 1.252 | 0.99 | |
| 112_P | 115_L | 1.249 | 0.99 | |
| 142_A | 145_P | 1.243 | 0.98 | |
| 112_P | 298_L | 1.227 | 0.98 | |
| 136_I | 225_L | 1.219 | 0.98 | |
| 136_I | 246_V | 1.214 | 0.98 | |
| 41_G | 286_Q | 1.214 | 0.98 | |
| 283_V | 286_Q | 1.212 | 0.98 | |
| 45_Q | 282_D | 1.21 | 0.98 | |
| 80_V | 260_A | 1.205 | 0.98 | |
| 261_I | 265_A | 1.199 | 0.98 | |
| 97_Q | 265_A | 1.196 | 0.98 | |
| 285_K | 300_A | 1.191 | 0.98 | |
| 281_P | 299_A | 1.182 | 0.98 | |
| 297_N | 300_A | 1.179 | 0.98 | |
| 98_K | 125_Y | 1.152 | 0.97 | |
| 32_Y | 77_Y | 1.151 | 0.97 | |
| 69_L | 80_V | 1.151 | 0.97 | |
| 47_T | 51_G | 1.141 | 0.97 | |
| 82_P | 260_A | 1.135 | 0.97 | |
| 317_D | 320_T | 1.133 | 0.97 | |
| 164_L | 223_V | 1.133 | 0.97 | |
| 42_L | 283_V | 1.128 | 0.97 | |
| 216_N | 220_E | 1.128 | 0.97 | |
| 218_Y | 243_I | 1.119 | 0.96 | |
| 282_D | 286_Q | 1.119 | 0.96 | |
| 190_K | 193_E | 1.119 | 0.96 | |
| 159_Y | 224_N | 1.11 | 0.96 | |
| 27_N | 267_N | 1.089 | 0.96 | |
| 272_L | 276_N | 1.088 | 0.96 | |
| 262_P | 265_A | 1.081 | 0.95 | |
| 162_S | 224_N | 1.079 | 0.95 | |
| 103_K | 272_L | 1.075 | 0.95 | |
| 45_Q | 283_V | 1.063 | 0.95 | |
| 213_N | 216_N | 1.062 | 0.95 | |
| 49_E | 282_D | 1.061 | 0.95 | |
| 126_S | 260_A | 1.056 | 0.95 | |
| 79_L | 274_L | 1.056 | 0.95 | |
| 217_P | 223_V | 1.056 | 0.95 | |
| 129_Y | 259_L | 1.056 | 0.95 | |
| 180_L | 198_E | 1.056 | 0.95 | |
| 143_V | 159_Y | 1.05 | 0.94 | |
| 138_V | 147_S | 1.049 | 0.94 | |
| 64_T | 67_A | 1.043 | 0.94 | |
| 157_P | 225_L | 1.04 | 0.94 | |
| 31_F | 79_L | 1.036 | 0.94 | |
| 98_K | 101_K | 1.024 | 0.93 | |
| 29_L | 274_L | 1.02 | 0.93 | |
| 132_G | 255_W | 1.017 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3uorA | 2 | 0.9914 | 100 | 0.224 | Contact Map | 0.787 |
| 4gl0A | 1 | 0.9511 | 100 | 0.228 | Contact Map | 0.734 |
| 4eqbA | 2 | 0.9425 | 100 | 0.229 | Contact Map | 0.781 |
| 1potA | 1 | 0.9339 | 100 | 0.246 | Contact Map | 0.721 |
| 4jdfA | 1 | 0.9339 | 100 | 0.255 | Contact Map | 0.66 |
| 2v84A | 1 | 0.9425 | 100 | 0.261 | Contact Map | 0.717 |
| 3ttmA | 2 | 0.9397 | 100 | 0.267 | Contact Map | 0.745 |
| 2xd3A | 1 | 0.9799 | 100 | 0.275 | Contact Map | 0.703 |
| 3ttnA | 2 | 0.9253 | 100 | 0.285 | Contact Map | 0.696 |
| 2zyoA | 1 | 0.9339 | 100 | 0.287 | Contact Map | 0.696 |
Sequence Conservation (Image Generated using WebLogo v3)