| UniProt: | P31133 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11629 | ||
| Length: | 370 (339) | ||
| Sequences: | 6676 | ||
| Seq/Len: | 19.69 |
| POTF
Paralog alert: 0.78 [within 20: 0.12] - ratio of genomes with paralogs Cluster includes: CYSP MALE MODA POTD POTF SUBI THIB UGPB YCJN YDCS YNJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 144_V | 265_S | 4.09 | 1.00 | |
| 99_Q | 289_K | 4.048 | 1.00 | |
| 145_D | 263_N | 3.636 | 1.00 | |
| 212_D | 216_K | 3.576 | 1.00 | |
| 53_T | 294_Q | 3.402 | 1.00 | |
| 33_H | 58_V | 3.381 | 1.00 | |
| 31_T | 56_K | 3.338 | 1.00 | |
| 48_N | 298_Y | 3.291 | 1.00 | |
| 55_I | 291_E | 3.207 | 1.00 | |
| 43_P | 47_A | 3.124 | 1.00 | |
| 111_N | 320_A | 3.112 | 1.00 | |
| 50_E | 56_K | 2.937 | 1.00 | |
| 215_L | 219_P | 2.861 | 1.00 | |
| 49_F | 294_Q | 2.819 | 1.00 | |
| 31_T | 58_V | 2.763 | 1.00 | |
| 142_Y | 265_S | 2.707 | 1.00 | |
| 47_A | 51_K | 2.672 | 1.00 | |
| 294_Q | 297_N | 2.63 | 1.00 | |
| 301_R | 304_V | 2.6 | 1.00 | |
| 48_N | 307_H | 2.579 | 1.00 | |
| 44_D | 47_A | 2.55 | 1.00 | |
| 48_N | 51_K | 2.523 | 1.00 | |
| 100_P | 127_N | 2.443 | 1.00 | |
| 100_P | 128_K | 2.365 | 1.00 | |
| 164_L | 216_K | 2.32 | 1.00 | |
| 63_D | 67_V | 2.21 | 1.00 | |
| 52_E | 301_R | 2.202 | 1.00 | |
| 166_P | 220_N | 2.154 | 1.00 | |
| 147_V | 240_V | 2.147 | 1.00 | |
| 298_Y | 304_V | 2.146 | 1.00 | |
| 288_N | 291_E | 2.142 | 1.00 | |
| 204_D | 208_G | 2.12 | 1.00 | |
| 114_P | 118_K | 2.059 | 1.00 | |
| 81_L | 296_L | 2.035 | 1.00 | |
| 47_A | 50_E | 2.029 | 1.00 | |
| 48_N | 52_E | 2.017 | 1.00 | |
| 82_V | 283_P | 1.989 | 1.00 | |
| 46_V | 295_F | 1.977 | 1.00 | |
| 158_D | 270_K | 1.956 | 1.00 | |
| 49_F | 55_I | 1.932 | 1.00 | |
| 327_A | 331_E | 1.927 | 1.00 | |
| 159_S | 162_L | 1.923 | 1.00 | |
| 286_A | 289_K | 1.892 | 1.00 | |
| 50_E | 53_T | 1.875 | 1.00 | |
| 46_V | 50_E | 1.872 | 1.00 | |
| 290_D | 294_Q | 1.868 | 1.00 | |
| 144_V | 148_K | 1.867 | 1.00 | |
| 98_F | 281_A | 1.864 | 1.00 | |
| 306_A | 310_D | 1.856 | 1.00 | |
| 80_D | 288_N | 1.824 | 1.00 | |
| 157_V | 162_L | 1.816 | 1.00 | |
| 327_A | 330_R | 1.799 | 1.00 | |
| 122_K | 128_K | 1.781 | 1.00 | |
| 130_A | 279_V | 1.772 | 1.00 | |
| 46_V | 57_V | 1.764 | 1.00 | |
| 158_D | 162_L | 1.715 | 1.00 | |
| 162_L | 165_K | 1.699 | 1.00 | |
| 178_S | 238_I | 1.687 | 1.00 | |
| 161_D | 165_K | 1.686 | 1.00 | |
| 146_K | 239_C | 1.672 | 1.00 | |
| 207_T | 212_D | 1.661 | 1.00 | |
| 102_D | 127_N | 1.648 | 1.00 | |
| 208_G | 212_D | 1.644 | 1.00 | |
| 282_M | 293_Y | 1.612 | 1.00 | |
| 99_Q | 284_A | 1.608 | 1.00 | |
| 55_I | 294_Q | 1.602 | 1.00 | |
| 155_A | 158_D | 1.594 | 1.00 | |
| 96_G | 284_A | 1.592 | 1.00 | |
| 143_N | 146_K | 1.586 | 1.00 | |
| 233_L | 264_V | 1.58 | 1.00 | |
| 145_D | 149_A | 1.572 | 1.00 | |
| 213_L | 216_K | 1.562 | 1.00 | |
| 169_L | 176_G | 1.523 | 1.00 | |
| 216_K | 220_N | 1.523 | 1.00 | |
| 295_F | 299_L | 1.522 | 1.00 | |
| 289_K | 293_Y | 1.504 | 1.00 | |
| 338_P | 341_V | 1.502 | 1.00 | |
| 44_D | 48_N | 1.496 | 1.00 | |
| 46_V | 59_Y | 1.482 | 1.00 | |
| 49_F | 295_F | 1.475 | 1.00 | |
| 212_D | 215_L | 1.469 | 1.00 | |
| 57_V | 295_F | 1.462 | 1.00 | |
| 108_E | 297_N | 1.449 | 1.00 | |
| 113_D | 319_K | 1.444 | 1.00 | |
| 81_L | 292_A | 1.427 | 1.00 | |
| 139_G | 266_F | 1.426 | 1.00 | |
| 44_D | 307_H | 1.418 | 1.00 | |
| 80_D | 286_A | 1.417 | 1.00 | |
| 291_E | 294_Q | 1.393 | 0.99 | |
| 205_D | 208_G | 1.378 | 0.99 | |
| 282_M | 286_A | 1.371 | 0.99 | |
| 144_V | 263_N | 1.36 | 0.99 | |
| 161_D | 164_L | 1.349 | 0.99 | |
| 282_M | 296_L | 1.348 | 0.99 | |
| 93_L | 129_F | 1.337 | 0.99 | |
| 130_A | 281_A | 1.321 | 0.99 | |
| 136_A | 276_F | 1.317 | 0.99 | |
| 49_F | 298_Y | 1.314 | 0.99 | |
| 302_P | 306_A | 1.313 | 0.99 | |
| 146_K | 149_A | 1.299 | 0.99 | |
| 159_S | 271_E | 1.288 | 0.99 | |
| 307_H | 310_D | 1.283 | 0.99 | |
| 105_K | 293_Y | 1.28 | 0.99 | |
| 164_L | 217_L | 1.28 | 0.99 | |
| 339_A | 343_A | 1.268 | 0.99 | |
| 111_N | 318_N | 1.264 | 0.99 | |
| 191_L | 196_K | 1.259 | 0.99 | |
| 147_V | 168_N | 1.253 | 0.99 | |
| 34_I | 81_L | 1.251 | 0.99 | |
| 232_D | 237_D | 1.251 | 0.99 | |
| 318_N | 321_A | 1.244 | 0.98 | |
| 282_M | 292_A | 1.243 | 0.98 | |
| 114_P | 319_K | 1.24 | 0.98 | |
| 204_D | 207_T | 1.229 | 0.98 | |
| 33_H | 60_D | 1.224 | 0.98 | |
| 303_D | 307_H | 1.222 | 0.98 | |
| 49_F | 291_E | 1.218 | 0.98 | |
| 280_F | 296_L | 1.212 | 0.98 | |
| 164_L | 213_L | 1.201 | 0.98 | |
| 104_S | 293_Y | 1.196 | 0.98 | |
| 32_L | 291_E | 1.193 | 0.98 | |
| 143_N | 262_V | 1.192 | 0.98 | |
| 150_V | 153_E | 1.189 | 0.98 | |
| 48_N | 303_D | 1.184 | 0.98 | |
| 196_K | 205_D | 1.183 | 0.98 | |
| 149_A | 174_S | 1.178 | 0.98 | |
| 216_K | 219_P | 1.177 | 0.98 | |
| 30_K | 288_N | 1.17 | 0.97 | |
| 280_F | 299_L | 1.164 | 0.97 | |
| 306_A | 321_A | 1.163 | 0.97 | |
| 304_V | 307_H | 1.162 | 0.97 | |
| 82_V | 281_A | 1.161 | 0.97 | |
| 210_A | 365_K | 1.161 | 0.97 | |
| 194_L | 208_G | 1.159 | 0.97 | |
| 352_D | 355_I | 1.158 | 0.97 | |
| 213_L | 217_L | 1.153 | 0.97 | |
| 99_Q | 286_A | 1.151 | 0.97 | |
| 48_N | 304_V | 1.15 | 0.97 | |
| 307_H | 311_H | 1.147 | 0.97 | |
| 105_K | 290_D | 1.146 | 0.97 | |
| 45_T | 304_V | 1.137 | 0.97 | |
| 114_P | 117_L | 1.13 | 0.97 | |
| 49_F | 53_T | 1.13 | 0.97 | |
| 283_P | 286_A | 1.128 | 0.97 | |
| 225_H | 228_Q | 1.123 | 0.97 | |
| 210_A | 362_A | 1.113 | 0.96 | |
| 166_P | 170_E | 1.108 | 0.96 | |
| 326_S | 329_V | 1.106 | 0.96 | |
| 118_K | 122_K | 1.104 | 0.96 | |
| 302_P | 320_A | 1.103 | 0.96 | |
| 163_I | 177_V | 1.099 | 0.96 | |
| 35_Y | 79_F | 1.093 | 0.96 | |
| 147_V | 153_E | 1.085 | 0.96 | |
| 340_D | 343_A | 1.082 | 0.96 | |
| 202_K | 205_D | 1.081 | 0.95 | |
| 246_G | 314_Y | 1.08 | 0.95 | |
| 67_V | 70_G | 1.065 | 0.95 | |
| 30_K | 291_E | 1.062 | 0.95 | |
| 50_E | 54_G | 1.059 | 0.95 | |
| 342_R | 345_L | 1.058 | 0.95 | |
| 286_A | 292_A | 1.054 | 0.95 | |
| 167_E | 171_K | 1.051 | 0.94 | |
| 164_L | 220_N | 1.051 | 0.94 | |
| 36_N | 59_Y | 1.042 | 0.94 | |
| 232_D | 238_I | 1.037 | 0.94 | |
| 355_I | 358_V | 1.018 | 0.93 | |
| 168_N | 239_C | 1.014 | 0.93 | |
| 72_L | 82_V | 1.013 | 0.93 | |
| 293_Y | 297_N | 1.011 | 0.93 | |
| 284_A | 289_K | 1.01 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3uorA | 2 | 0.9649 | 100 | 0.27 | Contact Map | 0.753 |
| 3ttmA | 2 | 0.9324 | 100 | 0.277 | Contact Map | 0.752 |
| 4jdfA | 1 | 0.9243 | 100 | 0.281 | Contact Map | 0.663 |
| 4eqbA | 2 | 0.8892 | 100 | 0.292 | Contact Map | 0.786 |
| 3ttnA | 2 | 0.9162 | 100 | 0.298 | Contact Map | 0.712 |
| 4gl0A | 1 | 0.8973 | 100 | 0.3 | Contact Map | 0.745 |
| 1potA | 1 | 0.8757 | 100 | 0.32 | Contact Map | 0.73 |
| 3vxbA | 1 | 0.9676 | 100 | 0.332 | Contact Map | 0.68 |
| 2v84A | 1 | 0.9135 | 100 | 0.336 | Contact Map | 0.716 |
| 4c1uA | 1 | 0.9324 | 100 | 0.344 | Contact Map | 0.709 |
Sequence Conservation (Image Generated using WebLogo v3)