| UniProt: | P31550 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11574 | ||
| Length: | 327 (302) | ||
| Sequences: | 10548 | ||
| Seq/Len: | 34.93 |
| THIB
Paralog alert: 0.87 [within 20: 0.21] - ratio of genomes with paralogs Cluster includes: CYSP MALE MODA POTD POTF SUBI THIB UGPB YCJN YDCS YNJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 97_A | 256_P | 3.905 | 1.00 | |
| 131_K | 232_A | 3.634 | 1.00 | |
| 48_C | 261_K | 3.601 | 1.00 | |
| 43_A | 265_F | 3.575 | 1.00 | |
| 23_T | 53_K | 3.481 | 1.00 | |
| 21_V | 53_K | 3.385 | 1.00 | |
| 181_Q | 185_K | 3.36 | 1.00 | |
| 38_P | 42_K | 3.252 | 1.00 | |
| 50_C | 258_L | 3.236 | 1.00 | |
| 21_V | 51_E | 3.155 | 1.00 | |
| 132_N | 230_N | 3.145 | 1.00 | |
| 45_E | 51_E | 3.042 | 1.00 | |
| 184_Q | 188_K | 2.802 | 1.00 | |
| 43_A | 274_A | 2.764 | 1.00 | |
| 268_S | 271_F | 2.75 | 1.00 | |
| 43_A | 46_A | 2.646 | 1.00 | |
| 42_K | 46_A | 2.594 | 1.00 | |
| 261_K | 264_Q | 2.533 | 1.00 | |
| 129_Y | 232_A | 2.503 | 1.00 | |
| 39_V | 42_K | 2.477 | 1.00 | |
| 145_V | 185_K | 2.437 | 1.00 | |
| 255_Q | 258_L | 2.43 | 1.00 | |
| 44_F | 261_K | 2.363 | 1.00 | |
| 98_K | 114_N | 2.262 | 1.00 | |
| 96_F | 248_A | 2.247 | 1.00 | |
| 140_S | 143_E | 2.241 | 1.00 | |
| 143_E | 146_E | 2.208 | 1.00 | |
| 41_K | 262_F | 2.202 | 1.00 | |
| 273_N | 277_T | 2.2 | 1.00 | |
| 147_S | 189_K | 2.187 | 1.00 | |
| 44_F | 50_C | 2.182 | 1.00 | |
| 43_A | 47_D | 2.093 | 1.00 | |
| 256_P | 260_Q | 2.085 | 1.00 | |
| 42_K | 45_E | 2.059 | 1.00 | |
| 47_D | 268_S | 2.01 | 1.00 | |
| 133_K | 210_D | 1.994 | 1.00 | |
| 77_D | 255_Q | 1.988 | 1.00 | |
| 134_L | 211_L | 1.968 | 1.00 | |
| 58_E | 62_S | 1.967 | 1.00 | |
| 41_K | 45_E | 1.966 | 1.00 | |
| 79_V | 250_T | 1.943 | 1.00 | |
| 269_P | 273_N | 1.934 | 1.00 | |
| 45_E | 48_C | 1.929 | 1.00 | |
| 257_E | 261_K | 1.917 | 1.00 | |
| 253_S | 256_P | 1.863 | 1.00 | |
| 50_C | 261_K | 1.834 | 1.00 | |
| 98_K | 115_D | 1.832 | 1.00 | |
| 97_A | 251_A | 1.821 | 1.00 | |
| 139_Q | 143_E | 1.813 | 1.00 | |
| 130_D | 133_K | 1.811 | 1.00 | |
| 249_R | 263_L | 1.779 | 1.00 | |
| 185_K | 189_K | 1.778 | 1.00 | |
| 117_F | 246_V | 1.75 | 1.00 | |
| 139_Q | 237_S | 1.723 | 1.00 | |
| 41_K | 52_L | 1.715 | 1.00 | |
| 258_L | 261_K | 1.706 | 1.00 | |
| 181_Q | 184_Q | 1.698 | 1.00 | |
| 182_A | 185_K | 1.695 | 1.00 | |
| 313_Q | 316_A | 1.667 | 1.00 | |
| 138_P | 143_E | 1.642 | 1.00 | |
| 25_Y | 70_E | 1.637 | 1.00 | |
| 247_A | 263_L | 1.635 | 1.00 | |
| 68_R | 93_T | 1.632 | 1.00 | |
| 249_R | 259_A | 1.63 | 1.00 | |
| 78_V | 263_L | 1.616 | 1.00 | |
| 94_G | 251_A | 1.592 | 1.00 | |
| 185_K | 188_K | 1.586 | 1.00 | |
| 39_V | 43_A | 1.584 | 1.00 | |
| 22_L | 258_L | 1.579 | 1.00 | |
| 265_F | 271_F | 1.578 | 1.00 | |
| 102_A | 260_Q | 1.571 | 1.00 | |
| 47_D | 270_A | 1.558 | 1.00 | |
| 249_R | 260_Q | 1.552 | 1.00 | |
| 203_L | 208_E | 1.548 | 1.00 | |
| 62_S | 65_N | 1.547 | 1.00 | |
| 131_K | 230_N | 1.541 | 1.00 | |
| 126_A | 233_A | 1.537 | 1.00 | |
| 41_K | 54_L | 1.527 | 1.00 | |
| 44_F | 262_F | 1.522 | 1.00 | |
| 182_A | 186_L | 1.494 | 1.00 | |
| 131_K | 135_K | 1.479 | 1.00 | |
| 77_D | 253_S | 1.478 | 1.00 | |
| 257_E | 260_Q | 1.477 | 1.00 | |
| 44_F | 265_F | 1.467 | 1.00 | |
| 152_R | 210_D | 1.465 | 1.00 | |
| 142_K | 146_E | 1.456 | 1.00 | |
| 39_V | 274_A | 1.455 | 1.00 | |
| 271_F | 274_A | 1.45 | 1.00 | |
| 274_A | 277_T | 1.431 | 1.00 | |
| 20_P | 258_L | 1.429 | 1.00 | |
| 178_D | 181_Q | 1.415 | 1.00 | |
| 154_I | 209_S | 1.407 | 0.99 | |
| 91_S | 116_T | 1.399 | 0.99 | |
| 196_G | 199_E | 1.389 | 0.99 | |
| 97_A | 253_S | 1.385 | 0.99 | |
| 140_S | 238_E | 1.368 | 0.99 | |
| 44_F | 48_C | 1.364 | 0.99 | |
| 270_A | 273_N | 1.358 | 0.99 | |
| 145_V | 186_L | 1.343 | 0.99 | |
| 134_L | 149_Q | 1.342 | 0.99 | |
| 262_F | 266_M | 1.335 | 0.99 | |
| 142_K | 145_V | 1.329 | 0.99 | |
| 43_A | 270_A | 1.314 | 0.99 | |
| 98_K | 116_T | 1.313 | 0.99 | |
| 202_G | 206_K | 1.304 | 0.99 | |
| 23_T | 55_V | 1.299 | 0.99 | |
| 129_Y | 137_P | 1.296 | 0.99 | |
| 269_P | 285_A | 1.288 | 0.99 | |
| 26_T | 54_L | 1.281 | 0.99 | |
| 145_V | 189_K | 1.28 | 0.99 | |
| 260_Q | 264_Q | 1.275 | 0.99 | |
| 100_G | 114_N | 1.271 | 0.99 | |
| 52_L | 262_F | 1.27 | 0.99 | |
| 66_R | 70_E | 1.268 | 0.99 | |
| 274_A | 278_G | 1.267 | 0.99 | |
| 249_R | 253_S | 1.266 | 0.99 | |
| 145_V | 182_A | 1.24 | 0.98 | |
| 78_V | 259_A | 1.232 | 0.98 | |
| 117_F | 248_A | 1.219 | 0.98 | |
| 64_L | 90_A | 1.212 | 0.98 | |
| 291_A | 294_E | 1.208 | 0.98 | |
| 44_F | 258_L | 1.202 | 0.98 | |
| 45_E | 49_N | 1.202 | 0.98 | |
| 20_P | 255_Q | 1.19 | 0.98 | |
| 127_F | 211_L | 1.18 | 0.98 | |
| 247_A | 266_M | 1.171 | 0.98 | |
| 149_Q | 210_D | 1.164 | 0.97 | |
| 149_Q | 211_L | 1.16 | 0.97 | |
| 79_V | 248_A | 1.156 | 0.97 | |
| 40_V | 271_F | 1.134 | 0.97 | |
| 22_L | 262_F | 1.122 | 0.97 | |
| 203_L | 209_S | 1.12 | 0.96 | |
| 204_F | 231_Y | 1.116 | 0.96 | |
| 43_A | 271_F | 1.114 | 0.96 | |
| 250_T | 253_S | 1.11 | 0.96 | |
| 90_A | 96_F | 1.108 | 0.96 | |
| 102_A | 257_E | 1.098 | 0.96 | |
| 105_A | 264_Q | 1.084 | 0.96 | |
| 270_A | 274_A | 1.072 | 0.95 | |
| 97_A | 260_Q | 1.068 | 0.95 | |
| 309_E | 312_A | 1.063 | 0.95 | |
| 128_V | 214_S | 1.052 | 0.95 | |
| 78_V | 262_F | 1.043 | 0.94 | |
| 269_P | 286_N | 1.033 | 0.94 | |
| 273_N | 287_V | 1.029 | 0.94 | |
| 67_L | 79_V | 1.029 | 0.94 | |
| 35_G | 38_P | 1.025 | 0.93 | |
| 45_E | 52_L | 1.022 | 0.93 | |
| 89_A | 93_T | 1.018 | 0.93 | |
| 81_G | 248_A | 1.016 | 0.93 | |
| 24_V | 78_V | 1.013 | 0.93 | |
| 96_F | 116_T | 1.011 | 0.93 | |
| 309_E | 313_Q | 1.008 | 0.93 | |
| 47_D | 265_F | 1.005 | 0.93 | |
| 120_F | 247_A | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4edpA | 2 | 0.9694 | 100 | 0.253 | Contact Map | 0.769 |
| 2qryA | 4 | 0.9908 | 100 | 0.271 | Contact Map | 0.738 |
| 3pu5A | 1 | 0.9388 | 100 | 0.272 | Contact Map | 0.688 |
| 3rpwA | 1 | 0.9694 | 100 | 0.274 | Contact Map | 0.737 |
| 3c9hA | 2 | 0.9725 | 100 | 0.279 | Contact Map | 0.795 |
| 4i1dA | 4 | 0.9205 | 100 | 0.305 | Contact Map | 0.719 |
| 4elqA | 2 | 0.9572 | 100 | 0.309 | Contact Map | 0.769 |
| 2vozA | 2 | 0.9511 | 100 | 0.313 | Contact Map | 0.664 |
| 3uorA | 2 | 0.9817 | 100 | 0.319 | Contact Map | 0.782 |
| 4euoA | 1 | 0.9052 | 100 | 0.322 | Contact Map | 0.753 |
Sequence Conservation (Image Generated using WebLogo v3)