| UniProt: | P37329 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12427 | ||
| Length: | 257 (232) | ||
| Sequences: | 6565 | ||
| Seq/Len: | 28.30 |
| MODA
Paralog alert: 0.78 [within 20: 0.14] - ratio of genomes with paralogs Cluster includes: CYSP MALE MODA POTD POTF SUBI THIB UGPB YCJN YDCS YNJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 47_Q | 239_Y | 3.775 | 1.00 | |
| 140_A | 188_A | 2.996 | 1.00 | |
| 115_K | 207_V | 2.92 | 1.00 | |
| 30_T | 57_V | 2.85 | 1.00 | |
| 54_V | 232_T | 2.746 | 1.00 | |
| 28_K | 57_V | 2.724 | 1.00 | |
| 222_V | 237_Y | 2.709 | 1.00 | |
| 71_E | 93_K | 2.695 | 1.00 | |
| 49_K | 55_D | 2.675 | 1.00 | |
| 230_N | 234_K | 2.605 | 1.00 | |
| 28_K | 55_D | 2.367 | 1.00 | |
| 97_D | 230_N | 2.357 | 1.00 | |
| 42_Q | 46_T | 2.283 | 1.00 | |
| 52_K | 235_A | 2.198 | 1.00 | |
| 51_E | 244_Q | 2.18 | 1.00 | |
| 51_E | 242_G | 2.154 | 1.00 | |
| 242_G | 245_A | 2.152 | 1.00 | |
| 116_A | 205_K | 2.098 | 1.00 | |
| 47_Q | 248_I | 2.089 | 1.00 | |
| 229_N | 232_T | 2.032 | 1.00 | |
| 47_Q | 50_K | 2.028 | 1.00 | |
| 231_A | 235_A | 2.005 | 1.00 | |
| 46_T | 50_K | 1.998 | 1.00 | |
| 234_K | 238_D | 1.98 | 1.00 | |
| 243_P | 247_E | 1.978 | 1.00 | |
| 45_A | 236_F | 1.95 | 1.00 | |
| 222_V | 240_L | 1.921 | 1.00 | |
| 126_S | 213_D | 1.878 | 1.00 | |
| 46_T | 49_K | 1.844 | 1.00 | |
| 96_I | 223_A | 1.833 | 1.00 | |
| 43_D | 251_R | 1.829 | 1.00 | |
| 48_F | 54_V | 1.821 | 1.00 | |
| 43_D | 46_T | 1.79 | 1.00 | |
| 61_A | 65_T | 1.788 | 1.00 | |
| 247_E | 251_R | 1.762 | 1.00 | |
| 88_D | 92_D | 1.749 | 1.00 | |
| 224_V | 234_K | 1.703 | 1.00 | |
| 125_D | 212_E | 1.682 | 1.00 | |
| 29_I | 232_T | 1.676 | 1.00 | |
| 47_Q | 244_Q | 1.674 | 1.00 | |
| 38_T | 42_Q | 1.672 | 1.00 | |
| 138_R | 189_P | 1.637 | 1.00 | |
| 45_A | 58_S | 1.607 | 1.00 | |
| 115_K | 205_K | 1.601 | 1.00 | |
| 45_A | 49_K | 1.592 | 1.00 | |
| 90_A | 96_I | 1.585 | 1.00 | |
| 232_T | 235_A | 1.581 | 1.00 | |
| 67_A | 90_A | 1.565 | 1.00 | |
| 244_Q | 247_E | 1.562 | 1.00 | |
| 125_D | 129_N | 1.559 | 1.00 | |
| 114_P | 117_S | 1.551 | 1.00 | |
| 45_A | 56_V | 1.55 | 1.00 | |
| 117_S | 189_P | 1.543 | 1.00 | |
| 94_K | 226_E | 1.526 | 1.00 | |
| 179_A | 191_G | 1.509 | 1.00 | |
| 47_Q | 51_E | 1.5 | 1.00 | |
| 235_A | 238_D | 1.483 | 1.00 | |
| 44_I | 245_A | 1.482 | 1.00 | |
| 70_I | 79_F | 1.445 | 1.00 | |
| 113_A | 207_V | 1.442 | 1.00 | |
| 225_V | 228_H | 1.442 | 1.00 | |
| 231_A | 234_K | 1.432 | 1.00 | |
| 239_Y | 245_A | 1.426 | 1.00 | |
| 224_V | 237_Y | 1.415 | 1.00 | |
| 32_F | 76_A | 1.403 | 0.99 | |
| 78_L | 237_Y | 1.388 | 0.99 | |
| 110_V | 208_A | 1.383 | 0.99 | |
| 49_K | 52_K | 1.381 | 0.99 | |
| 68_R | 72_A | 1.364 | 0.99 | |
| 182_L | 187_E | 1.351 | 0.99 | |
| 80_I | 222_V | 1.348 | 0.99 | |
| 97_D | 226_E | 1.347 | 0.99 | |
| 91_V | 96_I | 1.344 | 0.99 | |
| 48_F | 235_A | 1.336 | 0.99 | |
| 129_N | 132_S | 1.331 | 0.99 | |
| 107_N | 218_V | 1.33 | 0.99 | |
| 131_T | 166_L | 1.32 | 0.99 | |
| 43_D | 252_Y | 1.299 | 0.99 | |
| 47_Q | 245_A | 1.298 | 0.99 | |
| 45_A | 55_D | 1.294 | 0.99 | |
| 67_A | 71_E | 1.263 | 0.99 | |
| 224_V | 233_V | 1.232 | 0.98 | |
| 44_I | 239_Y | 1.23 | 0.98 | |
| 162_A | 165_T | 1.226 | 0.98 | |
| 29_I | 236_F | 1.218 | 0.98 | |
| 112_V | 198_A | 1.21 | 0.98 | |
| 122_F | 134_L | 1.201 | 0.98 | |
| 128_T | 132_S | 1.191 | 0.98 | |
| 126_S | 212_E | 1.189 | 0.98 | |
| 248_I | 251_R | 1.184 | 0.98 | |
| 31_V | 236_F | 1.176 | 0.98 | |
| 48_F | 239_Y | 1.175 | 0.98 | |
| 89_Y | 93_K | 1.174 | 0.98 | |
| 54_V | 235_A | 1.164 | 0.97 | |
| 165_T | 168_P | 1.163 | 0.97 | |
| 224_V | 230_N | 1.159 | 0.97 | |
| 112_V | 183_V | 1.155 | 0.97 | |
| 43_D | 47_Q | 1.148 | 0.97 | |
| 70_I | 225_V | 1.144 | 0.97 | |
| 77_D | 229_N | 1.141 | 0.97 | |
| 135_N | 190_L | 1.131 | 0.97 | |
| 31_V | 58_S | 1.121 | 0.97 | |
| 131_T | 165_T | 1.121 | 0.97 | |
| 155_E | 216_K | 1.119 | 0.96 | |
| 48_F | 232_T | 1.112 | 0.96 | |
| 102_Q | 241_K | 1.091 | 0.96 | |
| 246_A | 256_I | 1.074 | 0.95 | |
| 244_Q | 248_I | 1.074 | 0.95 | |
| 193_V | 198_A | 1.06 | 0.95 | |
| 79_F | 223_A | 1.054 | 0.95 | |
| 133_L | 136_G | 1.05 | 0.94 | |
| 245_A | 248_I | 1.05 | 0.94 | |
| 71_E | 95_A | 1.044 | 0.94 | |
| 78_L | 233_V | 1.035 | 0.94 | |
| 80_I | 104_L | 1.034 | 0.94 | |
| 31_V | 78_L | 1.033 | 0.94 | |
| 63_S | 81_S | 1.029 | 0.94 | |
| 175_D | 178_G | 1.011 | 0.93 | |
| 67_A | 86_W | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3rpwA | 1 | 0.9767 | 100 | 0.373 | Contact Map | 0.738 |
| 3c9hA | 2 | 0.9883 | 100 | 0.38 | Contact Map | 0.821 |
| 4elqA | 2 | 0.9689 | 100 | 0.384 | Contact Map | 0.797 |
| 2qryA | 4 | 0.9689 | 100 | 0.394 | Contact Map | 0.751 |
| 3gzgA | 3 | 0.9767 | 100 | 0.397 | Contact Map | 0.666 |
| 1atgA | 1 | 0.8716 | 100 | 0.399 | Contact Map | 0.653 |
| 4edpA | 2 | 0.9805 | 100 | 0.409 | Contact Map | 0.79 |
| 2vozA | 2 | 0.9689 | 100 | 0.412 | Contact Map | 0.718 |
| 3cg1A | 2 | 0.8988 | 100 | 0.414 | Contact Map | 0.704 |
| 4kd5C | 4 | 0.8949 | 100 | 0.416 | Contact Map | 0.805 |
Sequence Conservation (Image Generated using WebLogo v3)