| UniProt: | P75895 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13856 | ||
| Length: | 266 (254) | ||
| Sequences: | 23186 | ||
| Seq/Len: | 91.28 |
| RUTD
Paralog alert: 0.81 [within 20: 0.26] - ratio of genomes with paralogs Cluster includes: BIOH DLHH MENH MHPC PLDB RUTD YBFF YCJY YFHR YGHX YJFP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 83_A | 107_V | 4.296 | 1.00 | |
| 48_R | 69_E | 3.9 | 1.00 | |
| 32_Q | 248_N | 3.15 | 1.00 | |
| 207_S | 233_P | 3.07 | 1.00 | |
| 243_D | 246_T | 2.895 | 1.00 | |
| 202_Q | 254_G | 2.894 | 1.00 | |
| 81_H | 106_T | 2.758 | 1.00 | |
| 230_M | 250_L | 2.695 | 1.00 | |
| 71_H | 97_L | 2.687 | 1.00 | |
| 111_V | 247_F | 2.591 | 1.00 | |
| 83_A | 106_T | 2.528 | 1.00 | |
| 75_V | 104_S | 2.375 | 1.00 | |
| 5_L | 41_Q | 2.293 | 1.00 | |
| 39_E | 252_L | 2.288 | 1.00 | |
| 232_M | 250_L | 2.264 | 1.00 | |
| 74_L | 82_Y | 2.222 | 1.00 | |
| 71_H | 101_Y | 2.171 | 1.00 | |
| 221_H | 227_S | 2.142 | 1.00 | |
| 112_N | 209_D | 2.13 | 1.00 | |
| 207_S | 231_V | 2.101 | 1.00 | |
| 228_Q | 257_S | 2.047 | 1.00 | |
| 68_A | 100_D | 2.041 | 1.00 | |
| 97_L | 101_Y | 2.026 | 1.00 | |
| 235_G | 243_D | 1.964 | 1.00 | |
| 84_V | 94_G | 1.937 | 1.00 | |
| 91_A | 113_G | 1.937 | 1.00 | |
| 71_H | 75_V | 1.898 | 1.00 | |
| 71_H | 104_S | 1.889 | 1.00 | |
| 98_A | 108_L | 1.888 | 1.00 | |
| 201_V | 224_L | 1.881 | 1.00 | |
| 109_I | 251_L | 1.844 | 1.00 | |
| 96_Q | 100_D | 1.825 | 1.00 | |
| 35_V | 248_N | 1.824 | 1.00 | |
| 83_A | 109_I | 1.807 | 1.00 | |
| 214_T | 231_V | 1.795 | 1.00 | |
| 83_A | 255_L | 1.791 | 1.00 | |
| 94_G | 108_L | 1.78 | 1.00 | |
| 15_V | 41_Q | 1.762 | 1.00 | |
| 15_V | 43_V | 1.721 | 1.00 | |
| 19_I | 47_Q | 1.713 | 1.00 | |
| 45_Y | 70_L | 1.69 | 1.00 | |
| 249_A | 253_N | 1.673 | 1.00 | |
| 250_L | 253_N | 1.624 | 1.00 | |
| 33_L | 44_C | 1.605 | 1.00 | |
| 19_I | 70_L | 1.6 | 1.00 | |
| 219_E | 223_A | 1.595 | 1.00 | |
| 26_G | 52_N | 1.541 | 1.00 | |
| 101_Y | 104_S | 1.536 | 1.00 | |
| 47_Q | 93_V | 1.53 | 1.00 | |
| 43_V | 73_A | 1.529 | 1.00 | |
| 110_S | 113_G | 1.528 | 1.00 | |
| 18_L | 85_V | 1.524 | 1.00 | |
| 19_I | 94_G | 1.513 | 1.00 | |
| 67_A | 96_Q | 1.51 | 1.00 | |
| 70_L | 97_L | 1.502 | 1.00 | |
| 232_M | 235_G | 1.497 | 1.00 | |
| 24_G | 28_Y | 1.496 | 1.00 | |
| 64_A | 100_D | 1.495 | 1.00 | |
| 246_T | 250_L | 1.494 | 1.00 | |
| 193_H | 196_R | 1.493 | 1.00 | |
| 14_P | 83_A | 1.443 | 1.00 | |
| 97_L | 105_V | 1.424 | 1.00 | |
| 35_V | 252_L | 1.418 | 1.00 | |
| 18_L | 42_V | 1.392 | 0.99 | |
| 20_S | 50_T | 1.387 | 0.99 | |
| 26_G | 46_D | 1.381 | 0.99 | |
| 202_Q | 230_M | 1.378 | 0.99 | |
| 17_V | 74_L | 1.355 | 0.99 | |
| 62_S | 65_Q | 1.35 | 0.99 | |
| 23_G | 88_A | 1.348 | 0.99 | |
| 75_V | 101_Y | 1.34 | 0.99 | |
| 96_Q | 99_L | 1.332 | 0.99 | |
| 79_I | 82_Y | 1.33 | 0.99 | |
| 246_T | 249_A | 1.327 | 0.99 | |
| 109_I | 202_Q | 1.326 | 0.99 | |
| 74_L | 79_I | 1.324 | 0.99 | |
| 15_V | 79_I | 1.324 | 0.99 | |
| 108_L | 201_V | 1.324 | 0.99 | |
| 40_Y | 83_A | 1.311 | 0.99 | |
| 224_L | 227_S | 1.308 | 0.99 | |
| 218_S | 222_A | 1.307 | 0.99 | |
| 107_V | 258_L | 1.3 | 0.99 | |
| 87_H | 240_N | 1.294 | 0.99 | |
| 204_I | 250_L | 1.285 | 0.99 | |
| 247_F | 251_L | 1.28 | 0.99 | |
| 26_G | 44_C | 1.263 | 0.99 | |
| 20_S | 47_Q | 1.263 | 0.99 | |
| 195_D | 223_A | 1.258 | 0.99 | |
| 35_V | 38_Q | 1.255 | 0.99 | |
| 14_P | 106_T | 1.254 | 0.99 | |
| 45_Y | 73_A | 1.254 | 0.99 | |
| 205_C | 217_S | 1.249 | 0.99 | |
| 73_A | 77_A | 1.245 | 0.98 | |
| 35_V | 245_E | 1.238 | 0.98 | |
| 46_D | 51_G | 1.233 | 0.98 | |
| 235_G | 242_T | 1.218 | 0.98 | |
| 235_G | 239_C | 1.215 | 0.98 | |
| 207_S | 234_Y | 1.215 | 0.98 | |
| 67_A | 93_V | 1.208 | 0.98 | |
| 214_T | 218_S | 1.206 | 0.98 | |
| 97_L | 104_S | 1.201 | 0.98 | |
| 218_S | 229_K | 1.198 | 0.98 | |
| 85_V | 111_V | 1.176 | 0.98 | |
| 95_M | 110_S | 1.163 | 0.97 | |
| 40_Y | 256_A | 1.162 | 0.97 | |
| 85_V | 251_L | 1.161 | 0.97 | |
| 16_V | 85_V | 1.144 | 0.97 | |
| 17_V | 82_Y | 1.137 | 0.97 | |
| 82_Y | 105_V | 1.121 | 0.97 | |
| 71_H | 100_D | 1.118 | 0.96 | |
| 16_V | 40_Y | 1.113 | 0.96 | |
| 17_V | 70_L | 1.11 | 0.96 | |
| 99_L | 193_H | 1.106 | 0.96 | |
| 245_E | 249_A | 1.097 | 0.96 | |
| 204_I | 232_M | 1.096 | 0.96 | |
| 228_Q | 250_L | 1.094 | 0.96 | |
| 236_G | 242_T | 1.094 | 0.96 | |
| 21_G | 88_A | 1.093 | 0.96 | |
| 40_Y | 255_L | 1.09 | 0.96 | |
| 13_A | 41_Q | 1.08 | 0.95 | |
| 221_H | 229_K | 1.076 | 0.95 | |
| 109_I | 255_L | 1.064 | 0.95 | |
| 23_G | 50_T | 1.063 | 0.95 | |
| 84_V | 97_L | 1.061 | 0.95 | |
| 43_V | 77_A | 1.047 | 0.94 | |
| 205_C | 214_T | 1.044 | 0.94 | |
| 28_Y | 240_N | 1.043 | 0.94 | |
| 232_M | 246_T | 1.032 | 0.94 | |
| 85_V | 109_I | 1.031 | 0.94 | |
| 202_Q | 228_Q | 1.026 | 0.94 | |
| 232_M | 243_D | 1.025 | 0.93 | |
| 205_C | 231_V | 1.024 | 0.93 | |
| 107_V | 254_G | 1.022 | 0.93 | |
| 218_S | 221_H | 1.012 | 0.93 | |
| 219_E | 222_A | 1.011 | 0.93 | |
| 107_V | 200_P | 1.011 | 0.93 | |
| 37_E | 42_V | 1.009 | 0.93 | |
| 230_M | 246_T | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3v48A | 2 | 1 | 100 | 0.066 | Contact Map | 0.782 |
| 3om8A | 2 | 0.9361 | 100 | 0.13 | Contact Map | 0.781 |
| 2xuaA | 2 | 0.9511 | 100 | 0.136 | Contact Map | 0.855 |
| 2pujA | 1 | 0.9436 | 100 | 0.15 | Contact Map | 0.841 |
| 1ehyA | 4 | 0.9323 | 100 | 0.151 | Contact Map | 0.8 |
| 3oosA | 1 | 0.9323 | 100 | 0.152 | Contact Map | 0.728 |
| 1iupA | 1 | 0.9586 | 100 | 0.156 | Contact Map | 0.833 |
| 2xmzA | 1 | 0.9511 | 100 | 0.164 | Contact Map | 0.769 |
| 2wueA | 2 | 0.9398 | 100 | 0.167 | Contact Map | 0.84 |
| 3bf7A | 2 | 0.9248 | 100 | 0.167 | Contact Map | 0.776 |
Sequence Conservation (Image Generated using WebLogo v3)