| UniProt: | P39298 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12490 | ||
| Length: | 249 (238) | ||
| Sequences: | 27322 | ||
| Seq/Len: | 114.80 |
| YJFP
Paralog alert: 0.88 [within 20: 0.39] - ratio of genomes with paralogs Cluster includes: BIOH DLHH MENH MHPC PLDB RUTD YBFF YCJY YFHR YGHX YJFP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 110_A | 133_C | 4.604 | 1.00 | |
| 63_P | 90_E | 4.267 | 1.00 | |
| 195_L | 227_P | 3.348 | 1.00 | |
| 224_S | 240_A | 2.661 | 1.00 | |
| 53_A | 242_V | 2.614 | 1.00 | |
| 209_Q | 221_L | 2.558 | 1.00 | |
| 46_F | 238_L | 2.557 | 1.00 | |
| 190_L | 244_F | 2.509 | 1.00 | |
| 92_T | 124_I | 2.473 | 1.00 | |
| 125_T | 134_T | 2.448 | 1.00 | |
| 184_L | 187_R | 2.396 | 1.00 | |
| 226_Q | 240_A | 2.306 | 1.00 | |
| 108_R | 132_R | 2.26 | 1.00 | |
| 202_A | 225_W | 2.239 | 1.00 | |
| 95_R | 109_L | 2.166 | 1.00 | |
| 110_A | 245_F | 2.124 | 1.00 | |
| 137_M | 237_A | 2.106 | 1.00 | |
| 195_L | 225_W | 2.098 | 1.00 | |
| 92_T | 128_H | 2.077 | 1.00 | |
| 222_T | 247_Q | 2.057 | 1.00 | |
| 121_A | 134_T | 2.055 | 1.00 | |
| 111_V | 121_A | 2.044 | 1.00 | |
| 118_A | 139_G | 2.025 | 1.00 | |
| 110_A | 132_R | 2.021 | 1.00 | |
| 189_L | 212_L | 2.019 | 1.00 | |
| 136_S | 139_G | 1.953 | 1.00 | |
| 138_M | 197_D | 1.927 | 1.00 | |
| 89_Q | 127_R | 1.833 | 1.00 | |
| 92_T | 96_A | 1.781 | 1.00 | |
| 33_Y | 91_F | 1.775 | 1.00 | |
| 110_A | 135_A | 1.772 | 1.00 | |
| 180_H | 183_Q | 1.771 | 1.00 | |
| 135_A | 241_A | 1.762 | 1.00 | |
| 29_C | 56_R | 1.747 | 1.00 | |
| 124_I | 128_H | 1.744 | 1.00 | |
| 58_I | 94_L | 1.721 | 1.00 | |
| 239_D | 243_T | 1.687 | 1.00 | |
| 29_C | 58_I | 1.652 | 1.00 | |
| 226_Q | 229_V | 1.612 | 1.00 | |
| 123_G | 127_R | 1.604 | 1.00 | |
| 207_R | 211_A | 1.6 | 1.00 | |
| 40_S | 67_S | 1.598 | 1.00 | |
| 222_T | 240_A | 1.597 | 1.00 | |
| 33_Y | 62_A | 1.584 | 1.00 | |
| 49_A | 238_L | 1.555 | 1.00 | |
| 91_F | 124_I | 1.546 | 1.00 | |
| 240_A | 243_T | 1.529 | 1.00 | |
| 55_L | 246_R | 1.522 | 1.00 | |
| 190_L | 224_S | 1.517 | 1.00 | |
| 206_L | 210_Q | 1.512 | 1.00 | |
| 60_P | 91_F | 1.508 | 1.00 | |
| 193_H | 205_S | 1.502 | 1.00 | |
| 53_A | 246_R | 1.498 | 1.00 | |
| 47_A | 59_M | 1.495 | 1.00 | |
| 206_L | 225_W | 1.491 | 1.00 | |
| 33_Y | 121_A | 1.464 | 1.00 | |
| 135_A | 245_F | 1.45 | 1.00 | |
| 193_H | 202_A | 1.435 | 1.00 | |
| 34_H | 65_H | 1.429 | 1.00 | |
| 135_A | 190_L | 1.395 | 0.99 | |
| 88_M | 123_G | 1.385 | 0.99 | |
| 92_T | 127_R | 1.376 | 0.99 | |
| 195_L | 228_G | 1.351 | 0.99 | |
| 134_T | 189_L | 1.35 | 0.99 | |
| 40_S | 61_D | 1.339 | 0.99 | |
| 202_A | 206_L | 1.333 | 0.99 | |
| 182_E | 211_A | 1.33 | 0.99 | |
| 49_A | 242_V | 1.327 | 0.99 | |
| 105_L | 108_R | 1.303 | 0.99 | |
| 123_G | 126_A | 1.302 | 0.99 | |
| 237_A | 241_A | 1.294 | 0.99 | |
| 49_A | 52_Q | 1.283 | 0.99 | |
| 122_L | 136_S | 1.283 | 0.99 | |
| 27_L | 56_R | 1.283 | 0.99 | |
| 192_W | 226_Q | 1.265 | 0.99 | |
| 62_A | 120_T | 1.264 | 0.99 | |
| 55_L | 110_A | 1.261 | 0.99 | |
| 35_G | 115_S | 1.261 | 0.99 | |
| 32_F | 112_G | 1.251 | 0.99 | |
| 126_A | 180_H | 1.245 | 0.98 | |
| 60_P | 94_L | 1.241 | 0.98 | |
| 212_L | 221_L | 1.235 | 0.98 | |
| 95_R | 100_E | 1.23 | 0.98 | |
| 51_A | 57_V | 1.223 | 0.98 | |
| 38_S | 42_V | 1.216 | 0.98 | |
| 37_T | 115_S | 1.207 | 0.98 | |
| 196_D | 228_G | 1.199 | 0.98 | |
| 61_D | 66_G | 1.199 | 0.98 | |
| 209_Q | 223_C | 1.197 | 0.98 | |
| 100_E | 109_L | 1.194 | 0.98 | |
| 136_S | 191_L | 1.193 | 0.98 | |
| 94_L | 98_I | 1.187 | 0.98 | |
| 206_L | 223_C | 1.185 | 0.98 | |
| 32_F | 57_V | 1.175 | 0.98 | |
| 28_P | 110_A | 1.157 | 0.97 | |
| 30_V | 55_L | 1.149 | 0.97 | |
| 124_I | 131_V | 1.145 | 0.97 | |
| 100_E | 108_R | 1.144 | 0.97 | |
| 31_I | 95_R | 1.142 | 0.97 | |
| 85_L | 127_R | 1.138 | 0.97 | |
| 229_V | 233_I | 1.134 | 0.97 | |
| 114_A | 234_T | 1.12 | 0.96 | |
| 207_R | 210_Q | 1.1 | 0.96 | |
| 40_S | 59_M | 1.091 | 0.96 | |
| 214_E | 221_L | 1.085 | 0.96 | |
| 19_P | 56_R | 1.085 | 0.96 | |
| 33_Y | 60_P | 1.078 | 0.95 | |
| 96_A | 128_H | 1.078 | 0.95 | |
| 36_F | 116_M | 1.078 | 0.95 | |
| 191_L | 205_S | 1.07 | 0.95 | |
| 34_H | 62_A | 1.068 | 0.95 | |
| 112_G | 137_M | 1.065 | 0.95 | |
| 37_T | 65_H | 1.057 | 0.95 | |
| 83_I | 86_Q | 1.055 | 0.95 | |
| 30_V | 57_V | 1.042 | 0.94 | |
| 95_R | 124_I | 1.041 | 0.94 | |
| 205_S | 223_C | 1.03 | 0.94 | |
| 114_A | 138_M | 1.029 | 0.94 | |
| 28_P | 55_L | 1.025 | 0.93 | |
| 123_G | 180_H | 1.024 | 0.93 | |
| 109_L | 131_V | 1.023 | 0.93 | |
| 32_F | 43_Y | 1.017 | 0.93 | |
| 133_C | 188_P | 1.016 | 0.93 | |
| 97_A | 101_E | 1.016 | 0.93 | |
| 111_V | 124_I | 1.013 | 0.93 | |
| 49_A | 53_A | 1.013 | 0.93 | |
| 236_E | 240_A | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pe6A | 1 | 0.9357 | 100 | 0.225 | Contact Map | 0.812 |
| 1zoiA | 3 | 0.8916 | 100 | 0.227 | Contact Map | 0.845 |
| 2ecfA | 1 | 0.9438 | 100 | 0.23 | Contact Map | 0.645 |
| 2wtmA | 4 | 0.9277 | 100 | 0.23 | Contact Map | 0.798 |
| 2y6uA | 1 | 0.9639 | 100 | 0.232 | Contact Map | 0.752 |
| 2z3zA | 1 | 0.9478 | 100 | 0.238 | Contact Map | 0.686 |
| 1q0rA | 1 | 0.9116 | 100 | 0.243 | Contact Map | 0.79 |
| 3o4hA | 4 | 0.9277 | 100 | 0.244 | Contact Map | 0.715 |
| 3om8A | 2 | 0.8835 | 100 | 0.25 | Contact Map | 0.774 |
| 1mtzA | 1 | 0.9036 | 100 | 0.251 | Contact Map | 0.807 |
Sequence Conservation (Image Generated using WebLogo v3)