| UniProt: | Q7DFU6 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13008 | ||
| Length: | 278 (229) | ||
| Sequences: | 5162 | ||
| Seq/Len: | 22.54 |
| YGHX
Paralog alert: 0.72 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: BIOH DLHH MENH MHPC PLDB RUTD YBFF YCJY YFHR YGHX YJFP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 57_T | 66_E | 3.424 | 1.00 | |
| 179_A | 188_A | 2.911 | 1.00 | |
| 59_P | 66_E | 2.844 | 1.00 | |
| 175_S | 188_A | 2.842 | 1.00 | |
| 107_A | 270_L | 2.8 | 1.00 | |
| 238_E | 268_R | 2.552 | 1.00 | |
| 242_Y | 264_L | 2.496 | 1.00 | |
| 164_G | 277_L | 2.487 | 1.00 | |
| 214_E | 243_P | 2.428 | 1.00 | |
| 152_F | 156_Y | 2.379 | 1.00 | |
| 109_Y | 274_D | 2.338 | 1.00 | |
| 164_G | 273_F | 2.307 | 1.00 | |
| 189_V | 273_F | 2.282 | 1.00 | |
| 61_P | 148_A | 2.199 | 1.00 | |
| 54_E | 73_K | 2.198 | 1.00 | |
| 58_Y | 149_A | 2.141 | 1.00 | |
| 164_G | 187_C | 2.108 | 1.00 | |
| 259_K | 263_D | 2.024 | 1.00 | |
| 58_Y | 69_G | 2.005 | 1.00 | |
| 74_P | 110_I | 1.999 | 1.00 | |
| 56_I | 69_G | 1.966 | 1.00 | |
| 107_A | 274_D | 1.961 | 1.00 | |
| 228_A | 232_A | 1.926 | 1.00 | |
| 267_Q | 271_K | 1.907 | 1.00 | |
| 264_L | 268_R | 1.897 | 1.00 | |
| 83_A | 159_A | 1.882 | 1.00 | |
| 165_I | 175_S | 1.864 | 1.00 | |
| 69_G | 112_L | 1.856 | 1.00 | |
| 215_L | 244_G | 1.854 | 1.00 | |
| 238_E | 275_K | 1.842 | 1.00 | |
| 83_A | 153_M | 1.838 | 1.00 | |
| 71_L | 112_L | 1.81 | 1.00 | |
| 200_D | 203_K | 1.752 | 1.00 | |
| 189_V | 269_T | 1.752 | 1.00 | |
| 150_I | 163_V | 1.716 | 1.00 | |
| 152_F | 155_R | 1.694 | 1.00 | |
| 242_Y | 268_R | 1.686 | 1.00 | |
| 162_K | 186_A | 1.665 | 1.00 | |
| 165_I | 178_A | 1.662 | 1.00 | |
| 236_V | 276_Y | 1.639 | 1.00 | |
| 84_V | 104_V | 1.625 | 1.00 | |
| 227_E | 239_A | 1.606 | 1.00 | |
| 240_Y | 268_R | 1.59 | 1.00 | |
| 81_T | 110_I | 1.579 | 1.00 | |
| 272_W | 276_Y | 1.579 | 1.00 | |
| 87_V | 146_F | 1.551 | 1.00 | |
| 71_L | 110_I | 1.545 | 1.00 | |
| 189_V | 209_L | 1.543 | 1.00 | |
| 112_L | 149_A | 1.536 | 1.00 | |
| 103_R | 107_A | 1.524 | 1.00 | |
| 187_C | 276_Y | 1.522 | 1.00 | |
| 227_E | 231_K | 1.504 | 1.00 | |
| 87_V | 165_I | 1.478 | 1.00 | |
| 271_K | 275_K | 1.467 | 1.00 | |
| 151_E | 155_R | 1.466 | 1.00 | |
| 54_E | 156_Y | 1.45 | 1.00 | |
| 55_Y | 68_R | 1.448 | 1.00 | |
| 190_P | 193_G | 1.414 | 1.00 | |
| 231_K | 237_Y | 1.392 | 0.99 | |
| 224_P | 228_A | 1.37 | 0.99 | |
| 89_E | 169_C | 1.322 | 0.99 | |
| 85_V | 146_F | 1.302 | 0.99 | |
| 147_F | 151_E | 1.297 | 0.99 | |
| 151_E | 184_E | 1.276 | 0.99 | |
| 84_V | 109_Y | 1.274 | 0.99 | |
| 189_V | 211_H | 1.274 | 0.99 | |
| 83_A | 110_I | 1.263 | 0.99 | |
| 268_R | 271_K | 1.257 | 0.99 | |
| 214_E | 241_I | 1.244 | 0.98 | |
| 147_F | 182_Y | 1.243 | 0.98 | |
| 187_C | 272_W | 1.229 | 0.98 | |
| 211_H | 240_Y | 1.228 | 0.98 | |
| 86_V | 111_A | 1.221 | 0.98 | |
| 110_I | 158_Q | 1.218 | 0.98 | |
| 72_V | 113_A | 1.216 | 0.98 | |
| 224_P | 241_I | 1.21 | 0.98 | |
| 61_P | 144_N | 1.209 | 0.98 | |
| 57_T | 68_R | 1.203 | 0.98 | |
| 211_H | 265_A | 1.194 | 0.98 | |
| 263_D | 267_Q | 1.19 | 0.98 | |
| 103_R | 270_L | 1.186 | 0.98 | |
| 227_E | 237_Y | 1.186 | 0.98 | |
| 109_Y | 273_F | 1.167 | 0.97 | |
| 56_I | 152_F | 1.164 | 0.97 | |
| 230_L | 237_Y | 1.159 | 0.97 | |
| 179_A | 206_A | 1.157 | 0.97 | |
| 245_V | 261_A | 1.157 | 0.97 | |
| 230_L | 235_K | 1.154 | 0.97 | |
| 84_V | 111_A | 1.145 | 0.97 | |
| 117_L | 145_D | 1.133 | 0.97 | |
| 84_V | 273_F | 1.127 | 0.97 | |
| 161_G | 186_A | 1.123 | 0.97 | |
| 69_G | 149_A | 1.119 | 0.96 | |
| 270_L | 274_D | 1.118 | 0.96 | |
| 77_M | 81_T | 1.118 | 0.96 | |
| 72_V | 105_A | 1.109 | 0.96 | |
| 146_F | 178_A | 1.109 | 0.96 | |
| 86_V | 101_A | 1.105 | 0.96 | |
| 53_A | 72_V | 1.097 | 0.96 | |
| 104_V | 166_T | 1.076 | 0.95 | |
| 180_V | 204_I | 1.076 | 0.95 | |
| 112_L | 153_M | 1.072 | 0.95 | |
| 74_P | 81_T | 1.058 | 0.95 | |
| 87_V | 174_V | 1.055 | 0.95 | |
| 211_H | 269_T | 1.051 | 0.94 | |
| 188_A | 208_L | 1.05 | 0.94 | |
| 165_I | 188_A | 1.042 | 0.94 | |
| 202_A | 233_N | 1.04 | 0.94 | |
| 190_P | 210_L | 1.035 | 0.94 | |
| 62_N | 65_G | 1.031 | 0.94 | |
| 177_A | 181_A | 1.027 | 0.94 | |
| 207_P | 276_Y | 1.026 | 0.94 | |
| 148_A | 151_E | 1.026 | 0.94 | |
| 258_D | 261_A | 1.023 | 0.93 | |
| 154_Q | 157_P | 1.02 | 0.93 | |
| 240_Y | 264_L | 1.017 | 0.93 | |
| 187_C | 273_F | 1.015 | 0.93 | |
| 56_I | 112_L | 1.014 | 0.93 | |
| 214_E | 244_G | 1.012 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1zi8A | 1 | 0.7986 | 100 | 0.428 | Contact Map | 0.652 |
| 3f67A | 1 | 0.8094 | 100 | 0.436 | Contact Map | 0.743 |
| 1xfdA | 4 | 0.946 | 100 | 0.446 | Contact Map | 0.703 |
| 2ecfA | 1 | 0.9424 | 100 | 0.45 | Contact Map | 0.744 |
| 2hdwA | 2 | 0.9137 | 100 | 0.456 | Contact Map | 0.785 |
| 2z3zA | 1 | 0.8993 | 100 | 0.458 | Contact Map | 0.787 |
| 4hvtA | 1 | 0.9388 | 100 | 0.461 | Contact Map | 0.647 |
| 4a5sA | 2 | 0.9388 | 100 | 0.469 | Contact Map | 0.739 |
| 3azoA | 2 | 0.9568 | 100 | 0.471 | Contact Map | 0.702 |
| 3o4hA | 4 | 0.9209 | 100 | 0.473 | Contact Map | 0.832 |
Sequence Conservation (Image Generated using WebLogo v3)