| UniProt: | P77538 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13453 | ||
| Length: | 284 (233) | ||
| Sequences: | 6358 | ||
| Seq/Len: | 27.29 |
| YFHR
Paralog alert: 0.71 [within 20: 0.06] - ratio of genomes with paralogs Cluster includes: BIOH DLHH MENH MHPC PLDB RUTD YBFF YCJY YFHR YGHX YJFP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 151_V | 176_A | 3.614 | 1.00 | |
| 114_R | 131_D | 3.525 | 1.00 | |
| 53_E | 61_R | 3.242 | 1.00 | |
| 225_K | 252_P | 2.964 | 1.00 | |
| 104_R | 273_V | 2.825 | 1.00 | |
| 239_Y | 246_K | 2.544 | 1.00 | |
| 84_A | 132_T | 2.496 | 1.00 | |
| 55_T | 61_R | 2.458 | 1.00 | |
| 80_T | 107_N | 2.33 | 1.00 | |
| 247_R | 278_S | 2.293 | 1.00 | |
| 179_L | 182_T | 2.241 | 1.00 | |
| 249_I | 271_Q | 2.237 | 1.00 | |
| 106_F | 277_L | 2.196 | 1.00 | |
| 151_V | 276_I | 2.178 | 1.00 | |
| 251_I | 271_Q | 2.118 | 1.00 | |
| 247_R | 271_Q | 2.074 | 1.00 | |
| 54_F | 135_A | 2.072 | 1.00 | |
| 61_R | 120_K | 2.044 | 1.00 | |
| 58_D | 114_R | 2 | 1.00 | |
| 178_I | 276_I | 1.997 | 1.00 | |
| 109_F | 135_A | 1.948 | 1.00 | |
| 232_W | 250_L | 1.947 | 1.00 | |
| 57_K | 134_S | 1.941 | 1.00 | |
| 178_I | 272_M | 1.929 | 1.00 | |
| 152_L | 162_I | 1.914 | 1.00 | |
| 52_V | 64_G | 1.884 | 1.00 | |
| 166_I | 177_V | 1.878 | 1.00 | |
| 222_I | 251_I | 1.866 | 1.00 | |
| 236_E | 250_L | 1.858 | 1.00 | |
| 236_E | 240_S | 1.853 | 1.00 | |
| 162_I | 177_V | 1.843 | 1.00 | |
| 225_K | 250_L | 1.841 | 1.00 | |
| 60_T | 120_K | 1.797 | 1.00 | |
| 223_H | 232_W | 1.733 | 1.00 | |
| 111_F | 135_A | 1.716 | 1.00 | |
| 219_L | 242_A | 1.696 | 1.00 | |
| 151_V | 280_L | 1.655 | 1.00 | |
| 232_W | 236_E | 1.645 | 1.00 | |
| 65_W | 91_M | 1.644 | 1.00 | |
| 146_N | 149_R | 1.643 | 1.00 | |
| 251_I | 254_G | 1.63 | 1.00 | |
| 221_L | 235_S | 1.63 | 1.00 | |
| 51_S | 63_Q | 1.605 | 1.00 | |
| 138_V | 142_R | 1.581 | 1.00 | |
| 140_R | 173_G | 1.578 | 1.00 | |
| 50_E | 142_R | 1.576 | 1.00 | |
| 99_S | 103_E | 1.551 | 1.00 | |
| 267_V | 271_Q | 1.543 | 1.00 | |
| 109_F | 139_V | 1.508 | 1.00 | |
| 225_K | 253_D | 1.499 | 1.00 | |
| 245_P | 279_A | 1.496 | 1.00 | |
| 137_N | 173_G | 1.477 | 1.00 | |
| 223_H | 235_S | 1.476 | 1.00 | |
| 163_L | 179_L | 1.457 | 1.00 | |
| 236_E | 248_L | 1.451 | 1.00 | |
| 226_A | 253_D | 1.448 | 1.00 | |
| 98_V | 110_M | 1.428 | 1.00 | |
| 84_A | 113_Y | 1.407 | 0.99 | |
| 64_G | 109_F | 1.405 | 0.99 | |
| 136_I | 174_I | 1.397 | 0.99 | |
| 133_Q | 137_N | 1.392 | 0.99 | |
| 239_Y | 248_L | 1.386 | 0.99 | |
| 53_E | 63_Q | 1.386 | 0.99 | |
| 112_D | 117_G | 1.384 | 0.99 | |
| 176_A | 279_A | 1.379 | 0.99 | |
| 86_G | 156_S | 1.369 | 0.99 | |
| 133_Q | 170_D | 1.364 | 0.99 | |
| 52_V | 138_V | 1.359 | 0.99 | |
| 68_P | 107_N | 1.352 | 0.99 | |
| 178_I | 220_L | 1.342 | 0.99 | |
| 220_L | 249_I | 1.332 | 0.99 | |
| 221_L | 238_L | 1.315 | 0.99 | |
| 222_I | 268_Y | 1.306 | 0.99 | |
| 101_L | 153_F | 1.293 | 0.99 | |
| 54_F | 64_G | 1.284 | 0.99 | |
| 220_L | 275_F | 1.281 | 0.99 | |
| 57_K | 130_D | 1.275 | 0.99 | |
| 153_F | 180_D | 1.262 | 0.99 | |
| 221_L | 239_Y | 1.26 | 0.99 | |
| 81_I | 106_F | 1.258 | 0.99 | |
| 100_W | 104_R | 1.24 | 0.98 | |
| 149_R | 175_R | 1.224 | 0.98 | |
| 84_A | 162_I | 1.224 | 0.98 | |
| 79_A | 149_R | 1.218 | 0.98 | |
| 137_N | 141_H | 1.218 | 0.98 | |
| 155_Q | 181_S | 1.218 | 0.98 | |
| 81_I | 101_L | 1.212 | 0.98 | |
| 136_I | 150_L | 1.205 | 0.98 | |
| 208_E | 241_L | 1.197 | 0.98 | |
| 100_W | 273_V | 1.197 | 0.98 | |
| 84_A | 111_F | 1.196 | 0.98 | |
| 63_Q | 118_K | 1.176 | 0.98 | |
| 225_K | 232_W | 1.176 | 0.98 | |
| 66_F | 109_F | 1.175 | 0.98 | |
| 78_I | 107_N | 1.165 | 0.97 | |
| 138_V | 141_H | 1.164 | 0.97 | |
| 270_E | 274_D | 1.161 | 0.97 | |
| 79_A | 106_F | 1.155 | 0.97 | |
| 104_R | 277_L | 1.142 | 0.97 | |
| 177_V | 219_L | 1.129 | 0.97 | |
| 222_I | 249_I | 1.11 | 0.96 | |
| 212_A | 241_L | 1.107 | 0.96 | |
| 210_Y | 213_S | 1.101 | 0.96 | |
| 179_L | 221_L | 1.1 | 0.96 | |
| 80_T | 145_V | 1.098 | 0.96 | |
| 69_S | 107_N | 1.096 | 0.96 | |
| 60_T | 114_R | 1.092 | 0.96 | |
| 64_G | 135_A | 1.089 | 0.96 | |
| 82_I | 136_I | 1.087 | 0.96 | |
| 80_T | 139_V | 1.086 | 0.96 | |
| 152_L | 174_I | 1.079 | 0.95 | |
| 264_H | 267_V | 1.071 | 0.95 | |
| 273_V | 277_L | 1.065 | 0.95 | |
| 235_S | 248_L | 1.053 | 0.95 | |
| 83_H | 153_F | 1.05 | 0.94 | |
| 56_A | 60_T | 1.046 | 0.94 | |
| 87_N | 157_I | 1.04 | 0.94 | |
| 91_M | 110_M | 1.016 | 0.93 | |
| 176_A | 276_I | 1.014 | 0.93 | |
| 266_D | 270_E | 1.01 | 0.93 | |
| 66_F | 107_N | 1.008 | 0.93 | |
| 51_S | 118_K | 1.005 | 0.93 | |
| 98_V | 108_V | 1.004 | 0.93 | |
| 83_H | 98_V | 1.003 | 0.93 | |
| 181_S | 257_I | 1.001 | 0.92 | |
| 156_S | 256_H | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pe6A | 1 | 0.8521 | 100 | 0.472 | Contact Map | 0.765 |
| 2wtmA | 4 | 0.7817 | 100 | 0.478 | Contact Map | 0.842 |
| 2ecfA | 1 | 0.9754 | 100 | 0.489 | Contact Map | 0.706 |
| 2hdwA | 2 | 0.9542 | 100 | 0.495 | Contact Map | 0.785 |
| 1k8qA | 2 | 0.8662 | 100 | 0.502 | Contact Map | 0.747 |
| 3ksrA | 1 | 0.8063 | 100 | 0.505 | Contact Map | 0.626 |
| 1zoiA | 3 | 0.743 | 100 | 0.509 | Contact Map | 0.797 |
| 3hjuA | 2 | 0.9085 | 100 | 0.51 | Contact Map | 0.806 |
| 3o4hA | 4 | 0.9437 | 100 | 0.514 | Contact Map | 0.81 |
| 2z3zA | 1 | 0.9331 | 100 | 0.516 | Contact Map | 0.742 |
Sequence Conservation (Image Generated using WebLogo v3)