| UniProt: | P07000 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10739 | ||
| Length: | 340 (291) | ||
| Sequences: | 9705 | ||
| Seq/Len: | 33.35 |
| PLDB
Paralog alert: 0.70 [within 20: 0.10] - ratio of genomes with paralogs Cluster includes: BIOH DLHH MENH MHPC PLDB RUTD YBFF YCJY YFHR YGHX YJFP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 134_Y | 158_A | 4.387 | 1.00 | |
| 90_R | 116_D | 4.189 | 1.00 | |
| 47_R | 83_D | 4.159 | 1.00 | |
| 268_E | 301_K | 3.887 | 1.00 | |
| 73_L | 319_L | 2.948 | 1.00 | |
| 298_L | 321_A | 2.893 | 1.00 | |
| 132_K | 157_D | 2.883 | 1.00 | |
| 42_P | 96_G | 2.865 | 1.00 | |
| 296_R | 328_R | 2.822 | 1.00 | |
| 300_I | 321_A | 2.808 | 1.00 | |
| 122_Q | 155_V | 2.786 | 1.00 | |
| 263_L | 325_F | 2.583 | 1.00 | |
| 118_A | 148_F | 2.496 | 1.00 | |
| 46_V | 67_Y | 2.412 | 1.00 | |
| 121_W | 133_R | 2.362 | 1.00 | |
| 311_K | 317_V | 2.347 | 1.00 | |
| 162_T | 318_A | 2.345 | 1.00 | |
| 134_Y | 157_D | 2.258 | 1.00 | |
| 160_A | 322_I | 2.235 | 1.00 | |
| 149_L | 159_I | 2.195 | 1.00 | |
| 268_E | 299_V | 2.191 | 1.00 | |
| 115_D | 151_R | 2.185 | 1.00 | |
| 45_F | 120_F | 2.168 | 1.00 | |
| 44_R | 94_R | 2.152 | 1.00 | |
| 320_H | 324_D | 2.141 | 1.00 | |
| 80_L | 323_V | 2.074 | 1.00 | |
| 43_V | 95_S | 2.055 | 1.00 | |
| 60_C | 117_L | 2.025 | 1.00 | |
| 275_N | 299_V | 2.014 | 1.00 | |
| 87_I | 117_L | 2.014 | 1.00 | |
| 81_G | 323_V | 1.991 | 1.00 | |
| 145_S | 159_I | 1.98 | 1.00 | |
| 134_Y | 160_A | 1.957 | 1.00 | |
| 118_A | 152_H | 1.956 | 1.00 | |
| 135_I | 145_S | 1.937 | 1.00 | |
| 142_G | 164_P | 1.933 | 1.00 | |
| 118_A | 122_Q | 1.922 | 1.00 | |
| 159_I | 262_T | 1.869 | 1.00 | |
| 60_C | 145_S | 1.825 | 1.00 | |
| 254_G | 257_D | 1.816 | 1.00 | |
| 47_R | 85_L | 1.784 | 1.00 | |
| 321_A | 324_D | 1.783 | 1.00 | |
| 134_Y | 326_F | 1.758 | 1.00 | |
| 76_D | 319_L | 1.741 | 1.00 | |
| 148_F | 152_H | 1.736 | 1.00 | |
| 303_A | 311_K | 1.723 | 1.00 | |
| 56_V | 85_L | 1.723 | 1.00 | |
| 300_I | 303_A | 1.712 | 1.00 | |
| 163_A | 270_E | 1.688 | 1.00 | |
| 262_T | 285_R | 1.686 | 1.00 | |
| 111_N | 151_R | 1.603 | 1.00 | |
| 279_D | 283_E | 1.592 | 1.00 | |
| 44_R | 67_Y | 1.577 | 1.00 | |
| 118_A | 155_V | 1.571 | 1.00 | |
| 282_C | 288_A | 1.558 | 1.00 | |
| 48_F | 86_I | 1.542 | 1.00 | |
| 87_I | 120_F | 1.539 | 1.00 | |
| 55_R | 82_F | 1.511 | 1.00 | |
| 161_L | 164_P | 1.508 | 1.00 | |
| 74_A | 86_I | 1.507 | 1.00 | |
| 117_L | 148_F | 1.505 | 1.00 | |
| 38_V | 119_A | 1.496 | 1.00 | |
| 121_W | 126_Q | 1.492 | 1.00 | |
| 61_P | 92_Q | 1.469 | 1.00 | |
| 89_H | 144_I | 1.464 | 1.00 | |
| 160_A | 263_L | 1.462 | 1.00 | |
| 76_D | 323_V | 1.46 | 1.00 | |
| 59_I | 84_V | 1.46 | 1.00 | |
| 58_V | 121_W | 1.446 | 1.00 | |
| 82_F | 327_N | 1.435 | 1.00 | |
| 56_V | 83_D | 1.423 | 1.00 | |
| 41_I | 90_R | 1.407 | 0.99 | |
| 49_R | 83_D | 1.389 | 0.99 | |
| 39_D | 119_A | 1.365 | 0.99 | |
| 57_V | 136_L | 1.356 | 0.99 | |
| 50_A | 53_H | 1.355 | 0.99 | |
| 158_A | 329_H | 1.354 | 0.99 | |
| 64_I | 139_S | 1.351 | 0.99 | |
| 263_L | 298_L | 1.344 | 0.99 | |
| 58_V | 117_L | 1.338 | 0.99 | |
| 60_C | 89_H | 1.33 | 0.99 | |
| 317_V | 321_A | 1.328 | 0.99 | |
| 136_L | 160_A | 1.323 | 0.99 | |
| 317_V | 320_H | 1.321 | 0.99 | |
| 37_G | 42_P | 1.319 | 0.99 | |
| 316_S | 320_H | 1.313 | 0.99 | |
| 67_Y | 86_I | 1.312 | 0.99 | |
| 59_I | 136_L | 1.306 | 0.99 | |
| 280_R | 284_L | 1.305 | 0.99 | |
| 303_A | 307_I | 1.304 | 0.99 | |
| 148_F | 156_C | 1.303 | 0.99 | |
| 76_D | 79_H | 1.303 | 0.99 | |
| 147_L | 151_R | 1.298 | 0.99 | |
| 82_F | 326_F | 1.293 | 0.99 | |
| 265_L | 318_A | 1.281 | 0.99 | |
| 88_D | 93_G | 1.278 | 0.99 | |
| 76_D | 316_S | 1.271 | 0.99 | |
| 85_L | 120_F | 1.267 | 0.99 | |
| 298_L | 317_V | 1.256 | 0.99 | |
| 59_I | 77_L | 1.247 | 0.99 | |
| 136_L | 322_I | 1.243 | 0.98 | |
| 152_H | 155_V | 1.241 | 0.98 | |
| 268_E | 302_G | 1.237 | 0.98 | |
| 109_R | 112_D | 1.229 | 0.98 | |
| 43_V | 116_D | 1.227 | 0.98 | |
| 256_G | 284_L | 1.226 | 0.98 | |
| 318_A | 322_I | 1.214 | 0.98 | |
| 48_F | 74_A | 1.213 | 0.98 | |
| 296_R | 321_A | 1.207 | 0.98 | |
| 58_V | 133_R | 1.203 | 0.98 | |
| 55_R | 134_Y | 1.201 | 0.98 | |
| 82_F | 134_Y | 1.196 | 0.98 | |
| 148_F | 155_V | 1.195 | 0.98 | |
| 78_F | 84_V | 1.19 | 0.98 | |
| 265_L | 321_A | 1.179 | 0.98 | |
| 85_L | 124_E | 1.177 | 0.98 | |
| 44_R | 88_D | 1.172 | 0.98 | |
| 135_I | 148_F | 1.154 | 0.97 | |
| 65_E | 69_K | 1.152 | 0.97 | |
| 57_V | 77_L | 1.149 | 0.97 | |
| 133_R | 156_C | 1.138 | 0.97 | |
| 121_W | 148_F | 1.134 | 0.97 | |
| 276_R | 279_D | 1.128 | 0.97 | |
| 278_H | 297_P | 1.123 | 0.97 | |
| 296_R | 324_D | 1.118 | 0.96 | |
| 114_V | 144_I | 1.112 | 0.96 | |
| 158_A | 325_F | 1.107 | 0.96 | |
| 279_D | 299_V | 1.105 | 0.96 | |
| 282_C | 297_P | 1.1 | 0.96 | |
| 279_D | 282_C | 1.093 | 0.96 | |
| 266_Q | 278_H | 1.075 | 0.95 | |
| 121_W | 155_V | 1.074 | 0.95 | |
| 285_R | 288_A | 1.072 | 0.95 | |
| 137_A | 145_S | 1.058 | 0.95 | |
| 269_E | 302_G | 1.053 | 0.95 | |
| 89_H | 140_M | 1.053 | 0.95 | |
| 135_I | 156_C | 1.052 | 0.95 | |
| 265_L | 300_I | 1.048 | 0.94 | |
| 39_D | 112_D | 1.043 | 0.94 | |
| 301_K | 317_V | 1.041 | 0.94 | |
| 61_P | 89_H | 1.036 | 0.94 | |
| 266_Q | 275_N | 1.036 | 0.94 | |
| 279_D | 297_P | 1.033 | 0.94 | |
| 160_A | 326_F | 1.02 | 0.93 | |
| 300_I | 311_K | 1.019 | 0.93 | |
| 115_D | 118_A | 1.016 | 0.93 | |
| 33_A | 45_F | 1.009 | 0.93 | |
| 57_V | 84_V | 1.007 | 0.93 | |
| 57_V | 82_F | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3om8A | 2 | 0.7794 | 100 | 0.4 | Contact Map | 0.764 |
| 3oosA | 1 | 0.7882 | 100 | 0.4 | Contact Map | 0.736 |
| 3bwxA | 1 | 0.8147 | 100 | 0.402 | Contact Map | 0.699 |
| 1ehyA | 4 | 0.8147 | 100 | 0.403 | Contact Map | 0.8 |
| 2pujA | 1 | 0.8029 | 100 | 0.403 | Contact Map | 0.834 |
| 1iupA | 1 | 0.8059 | 100 | 0.407 | Contact Map | 0.821 |
| 3pe6A | 1 | 0.8794 | 100 | 0.409 | Contact Map | 0.737 |
| 1q0rA | 1 | 0.8206 | 100 | 0.411 | Contact Map | 0.824 |
| 2xuaA | 2 | 0.7794 | 100 | 0.411 | Contact Map | 0.846 |
| 1zoiA | 3 | 0.7824 | 100 | 0.415 | Contact Map | 0.773 |
Sequence Conservation (Image Generated using WebLogo v3)