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YCBU - Uncharacterized fimbrial-like protein YcbU
UniProt: P75859 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13713
Length: 180 (153)
Sequences: 1472
Seq/Len: 9.62
YCBU
Paralog alert: 0.95 [within 20: 0.78] - ratio of genomes with paralogs
Cluster includes: ELFA FIMA1 FIMF FIMG FIMI SFMA SFMF YADN YBGD YCBU YCBV YDER YDES YFCP YFCV YGIL YRAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
122_V 155_L 3.444 1.00
89_A 177_L 2.98 1.00
118_T 165_T 2.858 1.00
65_A 68_T 2.806 1.00
123_Q 158_K 2.698 1.00
123_Q 156_R 2.665 1.00
76_N 150_T 2.441 1.00
157_Y 169_A 2.418 1.00
45_A 80_T 2.273 1.00
125_L 156_R 2.267 1.00
119_G 164_A 2.261 1.00
45_A 78_D 2.235 1.00
43_D 81_G 2.195 1.00
122_V 171_A 2.159 1.00
104_L 121_A 2.126 1.00
45_A 48_S 2.036 1.00
126_D 129_S 1.904 1.00
126_D 131_Q 1.835 1.00
107_L 169_A 1.814 1.00
64_Q 68_T 1.693 1.00
105_L 173_L 1.682 1.00
105_L 135_L 1.67 1.00
55_I 169_A 1.634 1.00
58_F 70_S 1.634 1.00
91_V 151_L 1.514 1.00
39_D 60_I 1.495 1.00
123_Q 132_E 1.487 1.00
78_D 150_T 1.475 1.00
97_A 103_T 1.45 1.00
69_V 156_R 1.436 1.00
63_F 159_S 1.427 1.00
69_V 123_Q 1.414 0.99
120_I 157_Y 1.414 0.99
76_N 152_K 1.409 0.99
98_D 160_T 1.381 0.99
74_D 154_Q 1.366 0.99
130_Q 154_Q 1.329 0.99
48_S 78_D 1.328 0.99
55_I 122_V 1.312 0.99
95_G 105_L 1.303 0.99
51_Q 77_I 1.301 0.99
104_L 158_K 1.298 0.99
105_L 171_A 1.282 0.99
117_A 120_I 1.274 0.99
56_G 71_T 1.272 0.99
56_G 169_A 1.257 0.98
48_S 51_Q 1.242 0.98
43_D 80_T 1.235 0.98
144_L 149_N 1.227 0.98
36_N 57_D 1.214 0.98
98_D 121_A 1.201 0.98
159_S 164_A 1.192 0.98
111_G 116_M 1.19 0.98
63_F 160_T 1.178 0.97
51_Q 175_F 1.171 0.97
32_H 172_V 1.128 0.96
63_F 120_I 1.126 0.96
55_I 157_Y 1.115 0.96
96_E 106_K 1.111 0.96
134_P 137_Q 1.108 0.96
75_L 124_I 1.098 0.96
41_G 149_N 1.087 0.95
58_F 157_Y 1.079 0.95
105_L 122_V 1.077 0.95
72_A 156_R 1.074 0.95
92_L 178_V 1.068 0.95
74_D 152_K 1.056 0.94
35_G 93_F 1.054 0.94
63_F 164_A 1.052 0.94
69_V 158_K 1.047 0.94
29_V 33_I 1.042 0.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jmrA10.83891000.277Contact Map0.657
2xg5B10.91111000.298Contact Map0.704
2jtyA10.86111000.303Contact Map0.724
2uy6B20.83331000.317Contact Map0.825
1pdkB10.81111000.323Contact Map0.703
3bwuF10.766799.90.358Contact Map0.802
4dwhB20.772299.90.374Contact Map0.769
2w07B10.772299.90.39Contact Map0.697
3bfqG10.722299.90.397Contact Map0.723
3jwnH20.888999.90.44Contact Map0.729
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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