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OPENSEQ.org
SFMA - Sfm fimbrial protein, A chain
UniProt: P0ABW5 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13881
Length: 180 (180)
Sequences: 1517
Seq/Len: 8.43
SFMA
Paralog alert: 0.95 [within 20: 0.80] - ratio of genomes with paralogs
Cluster includes: ELFA FIMA1 FIMF FIMG FIMI SFMA SFMF YADN YBGD YCBU YCBV YDER YDES YFCP YFCV YGIL YRAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
121_I 155_A 3.139 1.00
89_A 177_M 2.824 1.00
122_E 156_R 2.778 1.00
117_T 165_S 2.772 1.00
122_E 158_K 2.53 1.00
64_A 67_N 2.528 1.00
75_T 150_V 2.431 1.00
104_L 120_G 2.379 1.00
157_Y 169_A 2.28 1.00
124_L 156_R 2.264 1.00
118_G 164_A 2.121 1.00
107_I 169_A 2.118 1.00
42_S 80_D 2.084 1.00
44_N 79_N 2.078 1.00
121_I 171_A 2.049 1.00
105_L 133_P 2.014 1.00
105_L 173_A 1.976 1.00
44_N 77_Q 1.941 1.00
44_N 47_S 1.878 1.00
125_D 129_A 1.81 1.00
54_L 169_A 1.678 1.00
63_N 67_N 1.677 1.00
57_Y 69_S 1.583 1.00
122_E 130_I 1.553 1.00
38_N 59_T 1.523 1.00
95_G 105_L 1.493 1.00
62_F 159_G 1.446 0.99
91_V 151_L 1.425 0.99
144_L 149_N 1.385 0.99
75_T 152_H 1.365 0.99
97_A 103_N 1.344 0.99
73_P 154_S 1.328 0.99
3_L 6_I 1.327 0.99
116_A 119_V 1.317 0.99
42_S 79_N 1.291 0.98
54_L 121_I 1.28 0.98
55_G 169_A 1.279 0.98
47_S 50_Q 1.278 0.98
119_V 157_Y 1.259 0.98
50_Q 76_I 1.249 0.98
77_Q 150_V 1.248 0.98
47_S 77_Q 1.237 0.98
65_V 118_G 1.233 0.98
98_D 160_T 1.217 0.97
105_L 171_A 1.214 0.97
28_G 175_F 1.212 0.97
55_G 70_A 1.205 0.97
68_T 122_E 1.186 0.97
24_V 27_G 1.186 0.97
104_L 158_K 1.184 0.97
128_S 154_S 1.169 0.96
14_L 17_A 1.161 0.96
54_L 157_Y 1.155 0.96
8_S 15_F 1.145 0.96
8_S 11_A 1.137 0.96
3_L 7_S 1.124 0.95
9_A 12_A 1.122 0.95
50_Q 175_F 1.115 0.95
12_A 18_T 1.11 0.95
68_T 156_R 1.108 0.95
62_F 119_V 1.106 0.95
62_F 164_A 1.096 0.94
35_E 56_Q 1.094 0.94
105_L 121_I 1.091 0.94
71_L 156_R 1.09 0.94
159_G 164_A 1.086 0.94
2_K 6_I 1.083 0.94
98_D 120_G 1.081 0.94
40_A 149_N 1.081 0.94
11_A 16_A 1.08 0.94
132_K 135_G 1.067 0.93
61_I 69_S 1.06 0.93
96_Q 99_A 1.05 0.93
92_A 178_R 1.047 0.92
115_T 168_Q 1.046 0.92
6_I 9_A 1.042 0.92
62_F 160_T 1.04 0.92
74_F 123_I 1.034 0.92
5_F 8_S 1.031 0.92
94_S 134_D 1.025 0.91
8_S 12_A 1.023 0.91
57_Y 157_Y 1.023 0.91
96_Q 106_A 1.023 0.91
7_S 15_F 1.006 0.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jmrA10.851000.242Contact Map0.672
2jtyA10.87781000.243Contact Map0.731
2xg5B10.92221000.255Contact Map0.725
2uy6B20.83891000.264Contact Map0.833
1pdkB10.82781000.281Contact Map0.673
4dwhB20.78891000.33Contact Map0.748
3bwuF10.777899.90.339Contact Map0.796
2w07B10.777899.90.363Contact Map0.708
3bfqG10.722299.90.369Contact Map0.705
3jwnH20.883399.90.418Contact Map0.744
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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