| UniProt: | P76056 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13358 | ||
| Length: | 411 (375) | ||
| Sequences: | 4903 | ||
| Seq/Len: | 13.07 |
| INTR
Paralog alert: 0.65 [within 20: 0.06] - ratio of genomes with paralogs Cluster includes: FIMB FIME INTA INTB INTD INTE INTF INTQ INTR INTS INTZ XERC XERD |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 120_S | 130_D | 4.144 | 1.00 | |
| 362_A | 379_M | 3.539 | 1.00 | |
| 244_D | 247_K | 3.239 | 1.00 | |
| 240_W | 288_Y | 3.145 | 1.00 | |
| 353_N | 356_H | 3.128 | 1.00 | |
| 240_W | 317_V | 2.722 | 1.00 | |
| 46_L | 49_L | 2.655 | 1.00 | |
| 18_W | 25_R | 2.64 | 1.00 | |
| 239_A | 315_H | 2.609 | 1.00 | |
| 87_C | 171_L | 2.552 | 1.00 | |
| 272_R | 380_G | 2.526 | 1.00 | |
| 84_G | 88_D | 2.471 | 1.00 | |
| 361_F | 378_Q | 2.458 | 1.00 | |
| 248_G | 281_L | 2.446 | 1.00 | |
| 88_D | 114_R | 2.231 | 1.00 | |
| 86_L | 123_I | 2.214 | 1.00 | |
| 126_I | 172_L | 2.204 | 1.00 | |
| 359_H | 393_M | 2.18 | 1.00 | |
| 248_G | 278_Q | 2.18 | 1.00 | |
| 87_C | 110_L | 2.172 | 1.00 | |
| 366_L | 375_I | 2.171 | 1.00 | |
| 220_N | 287_Q | 2.142 | 1.00 | |
| 229_G | 361_F | 2.14 | 1.00 | |
| 138_L | 164_Y | 2.137 | 1.00 | |
| 86_L | 175_A | 2.119 | 1.00 | |
| 102_T | 106_T | 2.118 | 1.00 | |
| 127_R | 130_D | 2.112 | 1.00 | |
| 276_L | 280_A | 2.061 | 1.00 | |
| 361_F | 365_L | 2.054 | 1.00 | |
| 225_A | 354_P | 1.998 | 1.00 | |
| 99_T | 264_P | 1.981 | 1.00 | |
| 84_G | 119_E | 1.974 | 1.00 | |
| 245_L | 281_L | 1.917 | 1.00 | |
| 251_N | 273_T | 1.91 | 1.00 | |
| 131_I | 186_F | 1.899 | 1.00 | |
| 84_G | 114_R | 1.896 | 1.00 | |
| 249_I | 273_T | 1.868 | 1.00 | |
| 238_L | 243_V | 1.853 | 1.00 | |
| 225_A | 235_L | 1.845 | 1.00 | |
| 49_L | 53_E | 1.804 | 1.00 | |
| 232_H | 355_Y | 1.773 | 1.00 | |
| 240_W | 284_L | 1.749 | 1.00 | |
| 372_P | 388_Y | 1.746 | 1.00 | |
| 18_W | 27_R | 1.736 | 1.00 | |
| 242_D | 253_R | 1.681 | 1.00 | |
| 135_R | 165_I | 1.678 | 1.00 | |
| 116_I | 137_E | 1.677 | 1.00 | |
| 371_N | 374_F | 1.672 | 1.00 | |
| 221_L | 235_L | 1.654 | 1.00 | |
| 159_R | 163_N | 1.653 | 1.00 | |
| 224_F | 280_A | 1.653 | 1.00 | |
| 177_Q | 190_K | 1.653 | 1.00 | |
| 366_L | 392_G | 1.646 | 1.00 | |
| 117_I | 134_Y | 1.636 | 1.00 | |
| 83_F | 168_L | 1.628 | 1.00 | |
| 203_S | 206_E | 1.608 | 1.00 | |
| 381_H | 387_V | 1.583 | 1.00 | |
| 20_M | 25_R | 1.583 | 1.00 | |
| 230_L | 235_L | 1.574 | 1.00 | |
| 267_T | 270_G | 1.574 | 1.00 | |
| 86_L | 174_F | 1.574 | 1.00 | |
| 383_T | 389_E | 1.57 | 1.00 | |
| 244_D | 249_I | 1.569 | 1.00 | |
| 109_Q | 167_L | 1.554 | 1.00 | |
| 219_Q | 223_K | 1.548 | 1.00 | |
| 373_A | 376_A | 1.547 | 1.00 | |
| 362_A | 375_I | 1.54 | 1.00 | |
| 176_Y | 181_I | 1.539 | 1.00 | |
| 230_L | 252_V | 1.528 | 1.00 | |
| 202_L | 210_L | 1.522 | 1.00 | |
| 275_T | 378_Q | 1.517 | 1.00 | |
| 238_L | 250_V | 1.51 | 1.00 | |
| 172_L | 186_F | 1.507 | 1.00 | |
| 173_R | 187_E | 1.502 | 1.00 | |
| 281_L | 285_K | 1.488 | 1.00 | |
| 206_E | 209_A | 1.487 | 1.00 | |
| 91_T | 103_M | 1.481 | 1.00 | |
| 120_S | 125_H | 1.481 | 1.00 | |
| 172_L | 185_P | 1.468 | 1.00 | |
| 121_T | 125_H | 1.458 | 1.00 | |
| 82_T | 85_E | 1.45 | 1.00 | |
| 227_Y | 277_L | 1.443 | 1.00 | |
| 110_L | 114_R | 1.435 | 1.00 | |
| 174_F | 178_S | 1.435 | 1.00 | |
| 206_E | 350_R | 1.418 | 1.00 | |
| 200_D | 206_E | 1.416 | 1.00 | |
| 386_M | 390_I | 1.406 | 0.99 | |
| 226_V | 357_T | 1.399 | 0.99 | |
| 83_F | 171_L | 1.385 | 0.99 | |
| 99_T | 263_G | 1.379 | 0.99 | |
| 220_N | 283_A | 1.376 | 0.99 | |
| 9_E | 16_R | 1.375 | 0.99 | |
| 362_A | 366_L | 1.374 | 0.99 | |
| 365_L | 375_I | 1.357 | 0.99 | |
| 36_T | 42_K | 1.355 | 0.99 | |
| 132_L | 136_N | 1.353 | 0.99 | |
| 383_T | 386_M | 1.352 | 0.99 | |
| 99_T | 102_T | 1.343 | 0.99 | |
| 363_C | 394_W | 1.343 | 0.99 | |
| 83_F | 126_I | 1.336 | 0.99 | |
| 91_T | 107_K | 1.335 | 0.99 | |
| 30_L | 46_L | 1.325 | 0.99 | |
| 232_H | 236_A | 1.325 | 0.99 | |
| 230_L | 250_V | 1.311 | 0.99 | |
| 250_V | 276_L | 1.309 | 0.99 | |
| 277_L | 280_A | 1.304 | 0.99 | |
| 242_D | 254_R | 1.304 | 0.99 | |
| 238_L | 317_V | 1.3 | 0.99 | |
| 245_L | 276_L | 1.3 | 0.99 | |
| 241_E | 315_H | 1.297 | 0.99 | |
| 276_L | 281_L | 1.296 | 0.99 | |
| 179_G | 183_T | 1.291 | 0.99 | |
| 127_R | 182_S | 1.29 | 0.99 | |
| 202_L | 352_R | 1.281 | 0.99 | |
| 47_R | 51_V | 1.272 | 0.99 | |
| 173_R | 184_K | 1.272 | 0.99 | |
| 245_L | 285_K | 1.269 | 0.99 | |
| 221_L | 318_F | 1.261 | 0.99 | |
| 169_C | 173_R | 1.261 | 0.99 | |
| 340_W | 344_V | 1.259 | 0.99 | |
| 223_K | 279_P | 1.25 | 0.99 | |
| 84_G | 118_C | 1.25 | 0.99 | |
| 52_H | 56_S | 1.248 | 0.99 | |
| 106_T | 167_L | 1.248 | 0.99 | |
| 207_F | 226_V | 1.238 | 0.98 | |
| 45_N | 49_L | 1.232 | 0.98 | |
| 46_L | 50_I | 1.226 | 0.98 | |
| 239_A | 316_F | 1.225 | 0.98 | |
| 92_K | 95_E | 1.219 | 0.98 | |
| 385_Q | 389_E | 1.218 | 0.98 | |
| 239_A | 242_D | 1.217 | 0.98 | |
| 278_Q | 282_E | 1.217 | 0.98 | |
| 245_L | 248_G | 1.215 | 0.98 | |
| 154_K | 157_T | 1.213 | 0.98 | |
| 120_S | 126_I | 1.21 | 0.98 | |
| 53_E | 58_E | 1.208 | 0.98 | |
| 123_I | 172_L | 1.207 | 0.98 | |
| 95_E | 103_M | 1.207 | 0.98 | |
| 48_A | 55_N | 1.205 | 0.98 | |
| 88_D | 92_K | 1.202 | 0.98 | |
| 108_S | 111_K | 1.2 | 0.98 | |
| 49_L | 52_H | 1.2 | 0.98 | |
| 243_V | 250_V | 1.197 | 0.98 | |
| 234_E | 272_R | 1.191 | 0.98 | |
| 94_K | 98_L | 1.189 | 0.98 | |
| 83_F | 87_C | 1.185 | 0.98 | |
| 45_N | 52_H | 1.174 | 0.98 | |
| 221_L | 336_L | 1.174 | 0.98 | |
| 113_L | 168_L | 1.169 | 0.97 | |
| 95_E | 107_K | 1.163 | 0.97 | |
| 224_F | 318_F | 1.161 | 0.97 | |
| 209_A | 213_S | 1.157 | 0.97 | |
| 376_A | 387_V | 1.156 | 0.97 | |
| 373_A | 388_Y | 1.147 | 0.97 | |
| 121_T | 124_S | 1.145 | 0.97 | |
| 131_I | 168_L | 1.139 | 0.97 | |
| 165_I | 169_C | 1.137 | 0.97 | |
| 337_G | 354_P | 1.135 | 0.97 | |
| 266_K | 270_G | 1.134 | 0.97 | |
| 285_K | 288_Y | 1.132 | 0.97 | |
| 110_L | 171_L | 1.128 | 0.97 | |
| 37_N | 44_G | 1.125 | 0.97 | |
| 88_D | 107_K | 1.122 | 0.97 | |
| 379_M | 387_V | 1.118 | 0.96 | |
| 220_N | 286_E | 1.117 | 0.96 | |
| 374_F | 402_Q | 1.111 | 0.96 | |
| 227_Y | 280_A | 1.11 | 0.96 | |
| 132_L | 178_S | 1.105 | 0.96 | |
| 210_L | 340_W | 1.098 | 0.96 | |
| 112_T | 154_K | 1.097 | 0.96 | |
| 181_I | 185_P | 1.077 | 0.95 | |
| 363_C | 392_G | 1.072 | 0.95 | |
| 236_A | 333_V | 1.072 | 0.95 | |
| 246_E | 285_K | 1.07 | 0.95 | |
| 230_L | 238_L | 1.069 | 0.95 | |
| 112_T | 115_I | 1.068 | 0.95 | |
| 98_L | 102_T | 1.061 | 0.95 | |
| 202_L | 360_T | 1.059 | 0.95 | |
| 83_F | 117_I | 1.051 | 0.94 | |
| 352_R | 356_H | 1.05 | 0.94 | |
| 232_H | 354_P | 1.044 | 0.94 | |
| 359_H | 390_I | 1.04 | 0.94 | |
| 110_L | 113_L | 1.038 | 0.94 | |
| 370_A | 374_F | 1.035 | 0.94 | |
| 48_A | 52_H | 1.027 | 0.94 | |
| 134_Y | 164_Y | 1.027 | 0.94 | |
| 320_P | 329_P | 1.022 | 0.93 | |
| 365_L | 370_A | 1.021 | 0.93 | |
| 269_A | 382_E | 1.02 | 0.93 | |
| 214_E | 223_K | 1.019 | 0.93 | |
| 86_L | 178_S | 1.015 | 0.93 | |
| 171_L | 175_A | 1.013 | 0.93 | |
| 126_I | 131_I | 1.013 | 0.93 | |
| 239_A | 254_R | 1.011 | 0.93 | |
| 105_K | 108_S | 1.009 | 0.93 | |
| 362_A | 387_V | 1.008 | 0.93 | |
| 373_A | 377_S | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1z1bA | 2 | 0.8175 | 100 | 0.36 | Contact Map | 0.617 |
| 1a0pA | 1 | 0.6764 | 100 | 0.413 | Contact Map | 0.573 |
| 2a3vA | 4 | 0.7275 | 100 | 0.421 | Contact Map | 0.739 |
| 1z19A | 2 | 0.6691 | 100 | 0.427 | Contact Map | 0.622 |
| 4a8eA | 1 | 0.6715 | 100 | 0.461 | Contact Map | 0.67 |
| 1xo0A | 2 | 0.6934 | 100 | 0.461 | Contact Map | 0.507 |
| 4e0gA | 1 | 0.8273 | 100 | 0.53 | Contact Map | 0.385 |
| 3nkhA | 2 | 0.5353 | 100 | 0.542 | Contact Map | 0.797 |
| 1ae9A | 2 | 0.4112 | 100 | 0.617 | Contact Map | 0.613 |
| 1aihA | 4 | 0.3869 | 99.9 | 0.66 | Contact Map | 0.759 |
Sequence Conservation (Image Generated using WebLogo v3)